-
3
-
-
0037290876
-
Mammalian Toll-like receptors
-
Akira, S. 2003. Mammalian Toll-like receptors. Curr. Opin. Immunol. 15: 5-11.
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 5-11
-
-
Akira, S.1
-
4
-
-
0035881675
-
Cutting edge: Bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
-
Gewirtz, A., T. Navas, S. Lyons, P. Godowski, and J. Madara. 2001. Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J. Immunol. 167: 1882-1885.
-
(2001)
J. Immunol.
, vol.167
, pp. 1882-1885
-
-
Gewirtz, A.1
Navas, T.2
Lyons, S.3
Godowski, P.4
Madara, J.5
-
5
-
-
0035868953
-
Structure of the bacterial flagellar protofilament and implications for a switch for supercoiling
-
Samatey, F. A., K. Imada, S. Nagashima, F. Vonderviszt, T. Kumasaka, M. Yamamoto, and K. Namba. 2001. Structure of the bacterial flagellar protofilament and implications for a switch for supercoiling. Nature 410: 331-337.
-
(2001)
Nature
, vol.410
, pp. 331-337
-
-
Samatey, F.A.1
Imada, K.2
Nagashima, S.3
Vonderviszt, F.4
Kumasaka, T.5
Yamamoto, M.6
Namba, K.7
-
6
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
Hayashi, F., K. D. Smith, A. Ozinsky, T. R. Hawn, E. C. Yi, D. R. Goodlett, J. K. Eng, S. Akira, D. M. Underhill, and A. Aderem. 2001. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 410: 1099-1103.
-
(2001)
Nature
, vol.410
, pp. 1099-1103
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
Hawn, T.R.4
Yi, E.C.5
Goodlett, D.R.6
Eng, J.K.7
Akira, S.8
Underhill, D.M.9
Aderem, A.10
-
7
-
-
22144452520
-
The evolution of vertebrate Toll-like receptors
-
Roach, J. C., G. Glusman, L. Rowen, A. Kaur, M. K. Purcell, K. D. Smith, L. E. Hood, and A. Aderem. 2005. The evolution of vertebrate Toll-like receptors. Proc. Natl. Acad. Sci. USA 102: 9577-9582.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9577-9582
-
-
Roach, J.C.1
Glusman, G.2
Rowen, L.3
Kaur, A.4
Purcell, M.K.5
Smith, K.D.6
Hood, L.E.7
Aderem, A.8
-
8
-
-
0242693166
-
How bacteria assemble flagella
-
Macnab, R. M. 2003. How bacteria assemble flagella. Annu. Rev. Microbiol. 57: 77-100.
-
(2003)
Annu. Rev. Microbiol.
, vol.57
, pp. 77-100
-
-
Macnab, R.M.1
-
9
-
-
31844436647
-
Flagellin is an effective adjuvant for immunization against lethal respiratory challenge with Yersinia pestis
-
Honko, A. N., N. Sriranganathan, C. J. Lees, and S. B. Mizel. 2006. Flagellin is an effective adjuvant for immunization against lethal respiratory challenge with Yersinia pestis. Infect. Immun. 74: 1113-1120.
-
(2006)
Infect. Immun.
, vol.74
, pp. 1113-1120
-
-
Honko, A.N.1
Sriranganathan, N.2
Lees, C.J.3
Mizel, S.B.4
-
10
-
-
41249100259
-
Mucosal adjuvant activity of flagellin in aged mice
-
Bates, J. T., A. N. Honko, A. H. Graff, N. D. Kock, and S. B. Mizel. 2008. Mucosal adjuvant activity of flagellin in aged mice. Mech. Ageing Dev. 129: 271-281.
-
(2008)
Mech. Ageing Dev.
, vol.129
, pp. 271-281
-
-
Bates, J.T.1
Honko, A.N.2
Graff, A.H.3
Kock, N.D.4
Mizel, S.B.5
-
11
-
-
58149392737
-
Flagellin-F1-V fusion protein is an effective plague vaccine in mice and two species of nonhuman primates
-
Mizel, S. B., A. H. Graff, N. Sriranganathan, S. Ervin, C. J. Lees, M. O. Lively, R. R. Hantgan, M. J. Thomas, J. Wood, and B. Bell. 2009. Flagellin-F1-V fusion protein is an effective plague vaccine in mice and two species of nonhuman primates. Clin. Vaccine Immunol. 16: 21-28.
-
(2009)
Clin. Vaccine Immunol.
, vol.16
, pp. 21-28
-
-
Mizel, S.B.1
Graff, A.H.2
Sriranganathan, N.3
Ervin, S.4
Lees, C.J.5
Lively, M.O.6
Hantgan, R.R.7
Thomas, M.J.8
Wood, J.9
Bell, B.10
-
12
-
-
84855954988
-
+ T cells
-
+ T cells. Nat. Immunol. 13: 162-169.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 162-169
-
-
Kupz, A.1
Guarda, G.2
Gebhardt, T.3
Sander, L.E.4
Short, K.R.5
Diavatopoulos, D.A.6
Wijburg, O.L.7
Cao, H.8
Waithman, J.C.9
Chen, W.10
-
13
-
-
0036784636
-
Bacterial flagellin is an effective adjuvant for CD4+ T cells in vivo
-
McSorley, S., B. Ehst, Y. Yu, and A. Gewirtz. 2002. Bacterial flagellin is an effective adjuvant for CD4+ T cells in vivo. J. Immunol. 169: 3914-3923.
-
(2002)
J. Immunol.
, vol.169
, pp. 3914-3923
-
-
McSorley, S.1
Ehst, B.2
Yu, Y.3
Gewirtz, A.4
-
14
-
-
33747791726
-
Humoral immune response to flagellin requires T cells and activation of innate immunity
-
Sanders, C., Y. Yu, D. A. Moore, 3rd, I. R. Williams, and A. T. Gewirtz. 2006. Humoral immune response to flagellin requires T cells and activation of innate immunity. J. Immunol. 177: 2810-2818.
-
(2006)
J. Immunol.
, vol.177
, pp. 2810-2818
-
-
Sanders, C.1
Yu, Y.2
Moore III, D.A.3
Williams, I.R.4
Gewirtz, A.T.5
-
15
-
-
60749119489
-
Induction of adaptive immunity by flagellin does not require robust activation of innate immunity
-
Sanders, C. J., L. Franchi, F. Yarovinsky, S. Uematsu, S. Akira, G. Núñez, and A. T. Gewirtz. 2009. Induction of adaptive immunity by flagellin does not require robust activation of innate immunity. Eur. J. Immunol. 39: 359-371.
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 359-371
-
-
Sanders, C.J.1
Franchi, L.2
Yarovinsky, F.3
Uematsu, S.4
Akira, S.5
Núñez, G.6
Gewirtz, A.T.7
-
16
-
-
78649605448
-
TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin
-
Vijay-Kumar, M., F. A. Carvalho, J. D. Aitken, N. H. Fifadara, and A. T. Gewirtz. 2010. TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin. Eur. J. Immunol. 40: 3528-3534.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 3528-3534
-
-
Vijay-Kumar, M.1
Carvalho, F.A.2
Aitken, J.D.3
Fifadara, N.H.4
Gewirtz, A.T.5
-
17
-
-
29644433083
-
A bacterial flagellin, Vibrio vulnificus FlaB, has a strong mucosal adjuvant activity to induce protective immunity
-
Lee, S. E., S. Y. Kim, B. C. Jeong, Y. R. Kim, S. J. Bae, O. S. Ahn, J.-J. Lee, H.-C. Song, J. M. Kim, H. E. Choy, et al. 2006. A bacterial flagellin, Vibrio vulnificus FlaB, has a strong mucosal adjuvant activity to induce protective immunity. Infect. Immun. 74: 694-702.
-
(2006)
Infect. Immun.
, vol.74
, pp. 694-702
-
-
Lee, S.E.1
Kim, S.Y.2
Jeong, B.C.3
Kim, Y.R.4
Bae, S.J.5
Ahn, O.S.6
Lee, J.-J.7
Song, H.-C.8
Kim, J.M.9
Choy, H.E.10
-
18
-
-
0347776208
-
Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility
-
Smith, K. D., E. Andersen-Nissen, F. Hayashi, K. Strobe, M. A. Bergman, S. L. Barrett, B. T. Cookson, and A. Aderem. 2003. Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility. Nat. Immunol. 4: 1247-1253.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1247-1253
-
-
Smith, K.D.1
Andersen-Nissen, E.2
Hayashi, F.3
Strobe, K.4
Bergman, M.A.5
Barrett, S.L.6
Cookson, B.T.7
Aderem, A.8
-
19
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
-
Miao, E. A., C. M. Alpuche-Aranda, M. Dors, A. E. Clark, M. W. Bader, S. I. Miller, and A. Aderem. 2006. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat. Immunol. 7: 569-575.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 569-575
-
-
Miao, E.A.1
Alpuche-Aranda, C.M.2
Dors, M.3
Clark, A.E.4
Bader, M.W.5
Miller, S.I.6
Aderem, A.7
-
20
-
-
34548679608
-
TLR5 and Ipaf: Dual sensors of bacterial flagellin in the innate immune system
-
Miao, E. A., E. Andersen-Nissen, S. E. Warren, and A. Aderem. 2007. TLR5 and Ipaf: dual sensors of bacterial flagellin in the innate immune system. Semin. Immunopathol. 29: 275-288.
-
(2007)
Semin. Immunopathol.
, vol.29
, pp. 275-288
-
-
Miao, E.A.1
Andersen-Nissen, E.2
Warren, S.E.3
Aderem, A.4
-
21
-
-
80053349020
-
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
-
Zhao, Y., J. Yang, J. Shi, Y.-N. Gong, Q. Lu, H. Xu, L. Liu, and F. Shao. 2011. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 477: 596-600.
-
(2011)
Nature
, vol.477
, pp. 596-600
-
-
Zhao, Y.1
Yang, J.2
Shi, J.3
Gong, Y.-N.4
Lu, Q.5
Xu, H.6
Liu, L.7
Shao, F.8
-
22
-
-
80053379974
-
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
-
Kofoed, E. M., and R. E. Vance. 2011. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 477: 592-595.
-
(2011)
Nature
, vol.477
, pp. 592-595
-
-
Kofoed, E.M.1
Vance, R.E.2
-
23
-
-
0042238051
-
Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy
-
Yonekura, K., S. Maki-Yonekura, and K. Namba. 2003. Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy. Nature 424: 643-650.
-
(2003)
Nature
, vol.424
, pp. 643-650
-
-
Yonekura, K.1
Maki-Yonekura, S.2
Namba, K.3
-
24
-
-
0035892911
-
Salmonella flagellin-dependent proinflammatory responses are localized to the conserved amino and carboxyl regions of the protein
-
Eaves-Pyles, T. D., H. R. Wong, K. Odoms, and R. B. Pyles. 2001. Salmonella flagellin-dependent proinflammatory responses are localized to the conserved amino and carboxyl regions of the protein. J. Immunol. 167: 7009-7025.
-
(2001)
J. Immunol.
, vol.167
, pp. 7009-7025
-
-
Eaves-Pyles, T.D.1
Wong, H.R.2
Odoms, K.3
Pyles, R.B.4
-
25
-
-
78650647731
-
TLR-activated dendritic cells enhance the response of aged naive CD4 T cells via an IL-6-dependent mechanism
-
Jones, S. C., V. Brahmakshatriya, G. Huston, J. Dibble, and S. L. Swain. 2010. TLR-activated dendritic cells enhance the response of aged naive CD4 T cells via an IL-6-dependent mechanism. J. Immunol. 185: 6783-6894.
-
(2010)
J. Immunol.
, vol.185
, pp. 6783-6894
-
-
Jones, S.C.1
Brahmakshatriya, V.2
Huston, G.3
Dibble, J.4
Swain, S.L.5
-
27
-
-
24644442139
-
Effects of flagellin on innate and adaptive immunity
-
Honko, A. N., and S. B. Mizel. 2005. Effects of flagellin on innate and adaptive immunity. Immunol. Res. 33: 83-101.
-
(2005)
Immunol. Res.
, vol.33
, pp. 83-101
-
-
Honko, A.N.1
Mizel, S.B.2
-
28
-
-
84857858368
-
Dendritic cell-associated lectin 2 (DCAL2) defines a distinct CD8α-dendritic cell subset
-
Kasahara, S., and E. A. Clark. 2012. Dendritic cell-associated lectin 2 (DCAL2) defines a distinct CD8α-dendritic cell subset. J. Leukoc. Biol. 91: 437-448.
-
(2012)
J. Leukoc. Biol.
, vol.91
, pp. 437-448
-
-
Kasahara, S.1
Clark, E.A.2
-
29
-
-
9244249138
-
Responses to the soluble flagellar protein FliC are Th2, while those to FliC on Salmonella are Th1
-
Cunningham, A. F., M. Khan, J. Ball, K.-M. Toellner, K. Serre, E. Mohr, and I. C. MacLennan. 2004. Responses to the soluble flagellar protein FliC are Th2, while those to FliC on Salmonella are Th1. Eur. J. Immunol. 34: 2986-2995.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 2986-2995
-
-
Cunningham, A.F.1
Khan, M.2
Ball, J.3
Toellner, K.-M.4
Serre, K.5
Mohr, E.6
MacLennan, I.C.7
-
30
-
-
79957536264
-
Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-betregulated Th1 clearance of Salmonella typhimurium infection
-
Bobat, S., A. Flores-Langarica, J. Hitchcock, J. L. Marshall, R. A. Kingsley, M. Goodall, C. Gil-Cruz, K. Serre, D. L. Leyton, S. E. Letran, et al. 2011. Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-betregulated Th1 clearance of Salmonella typhimurium infection. Eur. J. Immunol. 41: 1606-1618.
-
(2011)
Eur. J. Immunol.
, vol.41
, pp. 1606-1618
-
-
Bobat, S.1
Flores-Langarica, A.2
Hitchcock, J.3
Marshall, J.L.4
Kingsley, R.A.5
Goodall, M.6
Gil-Cruz, C.7
Serre, K.8
Leyton, D.L.9
Letran, S.E.10
-
31
-
-
0034650406
-
Characterization of CD4 + T cell responses during natural infection with Salmonella typhimurium
-
McSorley, S., B. T. Cookson, and M. K. Jenkins. 2000. Characterization of CD4 + T cell responses during natural infection with Salmonella typhimurium. J. Immunol. 164: 986-993.
-
(2000)
J. Immunol.
, vol.164
, pp. 986-993
-
-
McSorley, S.1
Cookson, B.T.2
Jenkins, M.K.3
-
32
-
-
27744434894
-
CD4+-T-cell responses generated during murine Salmonella enterica serovar Typhimurium infection are directed towards multiple epitopes within the natural antigen FliC
-
Bergman, M. A., L. A. Cummings, R. C. Alaniz, L. Mayeda, I. Fellnerova, and B. T. Cookson. 2005. CD4+-T-cell responses generated during murine Salmonella enterica serovar Typhimurium infection are directed towards multiple epitopes within the natural antigen FliC. Infect. Immun. 73: 7226-7235.
-
(2005)
Infect. Immun.
, vol.73
, pp. 7226-7235
-
-
Bergman, M.A.1
Cummings, L.A.2
Alaniz, R.C.3
Mayeda, L.4
Fellnerova, I.5
Cookson, B.T.6
-
33
-
-
84890933681
-
CD103-CD11b+ dendritic cells regulate the sensitivity of CD4 T-cell responses to bacterial flagellin
-
Atif, S. M., S. Uematsu, S. Akira, and S. J. McSorley. 2014. CD103-CD11b+ dendritic cells regulate the sensitivity of CD4 T-cell responses to bacterial flagellin. Mucosal Immunol. 7: 68-77.
-
(2014)
Mucosal Immunol
, vol.7
, pp. 68-77
-
-
Atif, S.M.1
Uematsu, S.2
Akira, S.3
McSorley, S.J.4
-
34
-
-
2442652766
-
Flagellin promotes myeloid differentiation factor 88-dependent development of Th2-type response
-
Didierlaurent, A., I. Ferrero, L. A. Otten, B. Dubois, M. Reinhardt, H. Carlsen, R. Blomhoff, S. Akira, J. P. Kraehenbuhl, and J. C. Sirard. 2004. Flagellin promotes myeloid differentiation factor 88-dependent development of Th2-type response. J. Immunol. 172: 6922-6930.
-
(2004)
J. Immunol.
, vol.172
, pp. 6922-6930
-
-
Didierlaurent, A.1
Ferrero, I.2
Otten, L.A.3
Dubois, B.4
Reinhardt, M.5
Carlsen, H.6
Blomhoff, R.7
Akira, S.8
Kraehenbuhl, J.P.9
Sirard, J.C.10
-
35
-
-
84865974136
-
Construction and immunological evaluation of dual cell surface display of HIV-1 gag and Salmonella enterica serovar Typhimurium FliC in Lactobacillus acidophilus for vaccine delivery
-
Kajikawa, A., L. Zhang, J. Long, S. Nordone, L. Stoeker, A. LaVoy, S. Bumgardner, T. Klaenhammer, and G. Dean. 2012. Construction and immunological evaluation of dual cell surface display of HIV-1 gag and Salmonella enterica serovar Typhimurium FliC in Lactobacillus acidophilus for vaccine delivery. Clin. Vaccine Immunol. 19: 1374-1381.
-
(2012)
Clin. Vaccine Immunol.
, vol.19
, pp. 1374-1381
-
-
Kajikawa, A.1
Zhang, L.2
Long, J.3
Nordone, S.4
Stoeker, L.5
Lavoy, A.6
Bumgardner, S.7
Klaenhammer, T.8
Dean, G.9
-
36
-
-
79955098392
-
Enhanced mucosal immune responses to HIV viruslike particles containing a membrane-anchored adjuvant
-
Vassilieva, E. V., B.-Z. Wang, A. N. Vzorov, L. Wang, Y.-C. Wang, J. Bozja, R. Xu, and R. Compans. 2011. Enhanced mucosal immune responses to HIV viruslike particles containing a membrane-anchored adjuvant. MBio 2: e00328-10.
-
(2011)
MBio
, vol.2
-
-
Vassilieva, E.V.1
Wang, B.-Z.2
Vzorov, A.N.3
Wang, L.4
Wang, Y.-C.5
Bozja, J.6
Xu, R.7
Compans, R.8
-
37
-
-
84864546404
-
Enhanced influenza virus-like particle vaccines containing the extracellular domain of matrix protein 2 and a Toll-like receptor ligand
-
Wang, B.-Z., H. S. Gill, S.-M. Kang, L. Wang, Y.-C. Wang, E. V. Vassilieva, and R. W. Compans. 2012. Enhanced influenza virus-like particle vaccines containing the extracellular domain of matrix protein 2 and a Toll-like receptor ligand. Clin. Vaccine Immunol. 19: 1119-1125.
-
(2012)
Clin. Vaccine Immunol.
, vol.19
, pp. 1119-1125
-
-
Wang, B.-Z.1
Gill, H.S.2
Kang, S.-M.3
Wang, L.4
Wang, Y.-C.5
Vassilieva, E.V.6
Compans, R.W.7
-
38
-
-
78649741148
-
Safety and immunogenicity of a recombinant hemagglutinin influenza-flagellin fusion vaccine (VAX125) in healthy young adults
-
Treanor, J. J., D. N. Taylor, L. Tussey, C. Hay, C. Nolan, T. Fitzgerald, G. Liu, U. Kavita, L. Song, I. Dark, and A. Shaw. 2010. Safety and immunogenicity of a recombinant hemagglutinin influenza-flagellin fusion vaccine (VAX125) in healthy young adults. Vaccine 28: 8268-8274.
-
(2010)
Vaccine
, vol.28
, pp. 8268-8274
-
-
Treanor, J.J.1
Taylor, D.N.2
Tussey, L.3
Hay, C.4
Nolan, C.5
Fitzgerald, T.6
Liu, G.7
Kavita, U.8
Song, L.9
Dark, I.10
Shaw, A.11
-
39
-
-
79959736816
-
Induction of a potent immune response in the elderly using the TLR-5 agonist, flagellin, with a recombinant hemagglutinin influenza-flagellin fusion vaccine (VAX125, STF2.HA1 SI)
-
Taylor, D. N., J. J. Treanor, C. Strout, C. Johnson, T. Fitzgerald, U. Kavita, K. Ozer, L. Tussey, and A. Shaw. 2011. Induction of a potent immune response in the elderly using the TLR-5 agonist, flagellin, with a recombinant hemagglutinin influenza-flagellin fusion vaccine (VAX125, STF2.HA1 SI). Vaccine 29: 4897-4902.
-
(2011)
Vaccine
, vol.29
, pp. 4897-4902
-
-
Taylor, D.N.1
Treanor, J.J.2
Strout, C.3
Johnson, C.4
Fitzgerald, T.5
Kavita, U.6
Ozer, K.7
Tussey, L.8
Shaw, A.9
-
40
-
-
84864945063
-
Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response
-
Taylor, D. N., J. J. Treanor, E. A. Sheldon, C. Johnson, S. Umlauf, L. Song, U. Kavita, G. Liu, L. Tussey, K. Ozer, et al. 2012. Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response. Vaccine 30: 5761-5769.
-
(2012)
Vaccine
, vol.30
, pp. 5761-5769
-
-
Taylor, D.N.1
Treanor, J.J.2
Sheldon, E.A.3
Johnson, C.4
Umlauf, S.5
Song, L.6
Kavita, U.7
Liu, G.8
Tussey, L.9
Ozer, K.10
-
41
-
-
84864822911
-
Chimeric flagellin as the self-adjuvanting antigen for the activation of immune response against Helicobacter pylori
-
Mori, J., T. Vranac, B. Smrekar, M. Cernilec, V. Č. Serbec, S. Horvat, A. Ihan, M. Benčina, and R. Jerala. 2012. Chimeric flagellin as the self-adjuvanting antigen for the activation of immune response against Helicobacter pylori. Vaccine 30: 5856-5863.
-
(2012)
Vaccine
, vol.30
, pp. 5856-5863
-
-
Mori, J.1
Vranac, T.2
Smrekar, B.3
Cernilec, M.4
Serbec, V.C.5
Horvat, S.6
Ihan, A.7
Bencina, M.8
Jerala, R.9
-
42
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
Iwasaki, A., and R. Medzhitov. 2010. Regulation of adaptive immunity by the innate immune system. Science 327: 291-295.
-
(2010)
Science
, vol.327
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
43
-
-
79956079190
-
Immunological mechanisms of vaccination
-
Pulendran, B., and R. Ahmed. 2011. Immunological mechanisms of vaccination. Nat. Immunol. 12: 509-517.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 509-517
-
-
Pulendran, B.1
Ahmed, R.2
-
44
-
-
82255175484
-
Vaccines for the twenty-first century society
-
Rappuoli, R., C. W. Mandl, S. Black, and E. De Gregorio. 2011. Vaccines for the twenty-first century society. Nat. Rev. Immunol. 11: 865-872.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 865-872
-
-
Rappuoli, R.1
Mandl, C.W.2
Black, S.3
De Gregorio, E.4
-
45
-
-
79958026772
-
Enhanced antigen processing of flagellin fusion proteins promotes the antigenspecific CD8+ T cell response independently of TLR5 and MyD88
-
Bates, J. T., A. H. Graff, J. P. Phipps, J. M. Grayson, and S. B. Mizel. 2011. Enhanced antigen processing of flagellin fusion proteins promotes the antigenspecific CD8+ T cell response independently of TLR5 and MyD88. J. Immunol. 186: 6255-6262.
-
(2011)
J. Immunol.
, vol.186
, pp. 6255-6262
-
-
Bates, J.T.1
Graff, A.H.2
Phipps, J.P.3
Grayson, J.M.4
Mizel, S.B.5
-
46
-
-
84858677223
-
Sensing and reacting to microbes through the inflammasomes
-
Franchi, L., R. Muñoz-Planillo, and G. Núñez. 2012. Sensing and reacting to microbes through the inflammasomes. Nat. Immunol. 13: 325-332.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 325-332
-
-
Franchi, L.1
Muñoz-Planillo, R.2
Núñez, G.3
-
47
-
-
79953046719
-
The inflammasome NLRs in immunity, inflammation, and associated diseases
-
Davis, B. K., H. Wen, and J. P. Ting. 2011. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu. Rev. Immunol. 29: 707-735.
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 707-735
-
-
Davis, B.K.1
Wen, H.2
Ting, J.P.3
-
48
-
-
63149126030
-
Towards an understanding of the adjuvant action of aluminium
-
Marrack, P., A. S. McKee, and M. W. Munks. 2009. Towards an understanding of the adjuvant action of aluminium. Nat. Rev. Immunol. 9: 287-293.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 287-293
-
-
Marrack, P.1
McKee, A.S.2
Munks, M.W.3
-
49
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
Eisenbarth, S. C., O. R. Colegio, W. O'Connor, F. S. Sutterwala, and R. A. Flavell. 2008. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 453: 1122-1126.
-
(2008)
Nature
, vol.453
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor, W.3
Sutterwala, F.S.4
Flavell, R.A.5
-
50
-
-
47849087075
-
Cutting edge: Inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3
-
Li, H., S. B. Willingham, J. P. Ting, and F. Re. 2008. Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J. Immunol. 181: 17-21.
-
(2008)
J. Immunol.
, vol.181
, pp. 17-21
-
-
Li, H.1
Willingham, S.B.2
Ting, J.P.3
Re, F.4
-
51
-
-
79954597670
-
An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma
-
[Published erratum appears in 2011 Immunity 34: 627.]
-
Kool, M., M. A. Willart, M. van Nimwegen, I. Bergen, P. Pouliot, J. C. Virchow, N. Rogers, F. Osorio, C. Reis e Sousa, H. Hammad, and B. N. Lambrecht. 2011. An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma. [Published erratum appears in 2011 Immunity 34: 627.] Immunity 34: 527-540.
-
(2011)
Immunity
, vol.34
, pp. 527-540
-
-
Kool, M.1
Willart, M.A.2
Van Nimwegen, M.3
Bergen, I.4
Pouliot, P.5
Virchow, J.C.6
Rogers, N.7
Osorio, F.8
Reis Sousa E, C.9
Hammad, H.10
Lambrecht, B.N.11
-
52
-
-
79954587515
-
Silica crystals and aluminum salts regulate the production of prostaglandin in macrophages via NALP3 inflammasomeindependent mechanisms
-
Kuroda, E., K. J. Ishii, S. Uematsu, K. Ohata, C. Coban, S. Akira, K. Aritake, Y. Urade, and Y. Morimoto. 2011. Silica crystals and aluminum salts regulate the production of prostaglandin in macrophages via NALP3 inflammasomeindependent mechanisms. Immunity 34: 514-526.
-
(2011)
Immunity
, vol.34
, pp. 514-526
-
-
Kuroda, E.1
Ishii, K.J.2
Uematsu, S.3
Ohata, K.4
Coban, C.5
Akira, S.6
Aritake, K.7
Urade, Y.8
Morimoto, Y.9
-
53
-
-
84868090804
-
The human apoptosis inhibitor NAIP induces pyroptosis in macrophages infected with Legionella pneumophila
-
Katagiri, N., T. Shobuike, B. Chang, A. Kukita, and H. Miyamoto. 2012. The human apoptosis inhibitor NAIP induces pyroptosis in macrophages infected with Legionella pneumophila. Microbes Infect. 14: 1123-1132.
-
(2012)
Microbes Infect
, vol.14
, pp. 1123-1132
-
-
Katagiri, N.1
Shobuike, T.2
Chang, B.3
Kukita, A.4
Miyamoto, H.5
-
54
-
-
84869044838
-
Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin
-
Halff, E. F., C. A. Diebolder, M. Versteeg, A. Schouten, T. H. Brondijk, and E. G. Huizinga. 2012. Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin. J. Biol. Chem. 287: 38460-38472.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 38460-38472
-
-
Halff, E.F.1
Diebolder, C.A.2
Versteeg, M.3
Schouten, A.4
Brondijk, T.H.5
Huizinga, E.G.6
-
55
-
-
84862339477
-
NAIPs: Building an innate immune barrier against bacterial pathogens: NAIPs function as sensors that initiate innate immunity by detection of bacterial proteins in the host cell cytosol
-
Kofoed, E. M., and R. E. Vance. 2012. NAIPs: building an innate immune barrier against bacterial pathogens: NAIPs function as sensors that initiate innate immunity by detection of bacterial proteins in the host cell cytosol. BioEssays 34: 589-598.
-
(2012)
BioEssays
, vol.34
, pp. 589-598
-
-
Kofoed, E.M.1
Vance, R.E.2
-
56
-
-
84867121105
-
PRAT4A-dependent expression of cell surface TLR5 on neutrophils, classical monocytes and dendritic cells
-
Shibata, T., N. Takemura, Y. Motoi, Y. Goto, T. Karuppuchamy, K. Izawa, X. Li, S. Akashi-Takamura, N. Tanimura, J. Kunisawa, et al. 2012. PRAT4A-dependent expression of cell surface TLR5 on neutrophils, classical monocytes and dendritic cells. Int. Immunol. 24: 613-623.
-
(2012)
Int. Immunol.
, vol.24
, pp. 613-623
-
-
Shibata, T.1
Takemura, N.2
Motoi, Y.3
Goto, Y.4
Karuppuchamy, T.5
Izawa, K.6
Li, X.7
Akashi-Takamura, S.8
Tanimura, N.9
Kunisawa, J.10
-
57
-
-
78650648694
-
Flagellin as an adjuvant: Cellular mechanisms and potential
-
Mizel, S. B., and J. T. Bates. 2010. Flagellin as an adjuvant: cellular mechanisms and potential. J. Immunol. 185: 5677-5782.
-
(2010)
J. Immunol.
, vol.185
, pp. 5677-5782
-
-
Mizel, S.B.1
Bates, J.T.2
-
58
-
-
84857335818
-
Structural basis of TLR5-flagellin recognition and signaling
-
Yoon, S. I., O. Kurnasov, V. Natarajan, M. Hong, A. V. Gudkov, A. L. Osterman, and I. A. Wilson. 2012. Structural basis of TLR5-flagellin recognition and signaling. Science 335: 859-864.
-
(2012)
Science
, vol.335
, pp. 859-864
-
-
Yoon, S.I.1
Kurnasov, O.2
Natarajan, V.3
Hong, M.4
Gudkov, A.V.5
Osterman, A.L.6
Wilson, I.A.7
-
59
-
-
84874028928
-
Integrative inflammasome activity in the regulation of intestinal mucosal immune responses
-
Elinav, E., J. Henao-Mejia, and R. A. Flavell. 2013. Integrative inflammasome activity in the regulation of intestinal mucosal immune responses. Mucosal Immunol. 6: 4-13.
-
(2013)
Mucosal Immunol
, vol.6
, pp. 4-13
-
-
Elinav, E.1
Henao-Mejia, J.2
Flavell, R.A.3
-
60
-
-
78650368903
-
TLR5 functions as an endocytic receptor to enhance flagellin-specific adaptive immunity
-
Letran, S. E., S.-J. Lee, S. M. Atif, S. Uematsu, S. Akira, and S. J. McSorley. 2011. TLR5 functions as an endocytic receptor to enhance flagellin-specific adaptive immunity. Eur. J. Immunol. 41: 29-38.
-
(2011)
Eur. J. Immunol.
, vol.41
, pp. 29-38
-
-
Letran, S.E.1
Lee, S.-J.2
Atif, S.M.3
Uematsu, S.4
Akira, S.5
McSorley, S.J.6
-
61
-
-
84867063450
-
Rapid induction of inflammatory lipid mediators by the inflammasome in vivo
-
von Moltke, J., N. J. Trinidad, M. Moayeri, A. F. Kintzer, S. B. Wang, N. van Rooijen, C. R. Brown, B. A. Krantz, S. H. Leppla, K. Gronert, and R. E. Vance. 2012. Rapid induction of inflammatory lipid mediators by the inflammasome in vivo. Nature 490: 107-111.
-
(2012)
Nature
, vol.490
, pp. 107-111
-
-
Von Moltke, J.1
Trinidad, N.J.2
Moayeri, M.3
Kintzer, A.F.4
Wang, S.B.5
Van Rooijen, N.6
Brown, C.R.7
Krantz, B.A.8
Leppla, S.H.9
Gronert, K.10
Vance, R.E.11
-
62
-
-
21544448078
-
Evasion of Toll-like receptor 5 by flagellated bacteria
-
Andersen-Nissen, E., K. D. Smith, K. L. Strobe, S. L. Barrett, B. T. Cookson, S. M. Logan, and A. Aderem. 2005. Evasion of Toll-like receptor 5 by flagellated bacteria. Proc. Natl. Acad. Sci. USA 102: 9247-9252.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9247-9252
-
-
Andersen-Nissen, E.1
Smith, K.D.2
Strobe, K.L.3
Barrett, S.L.4
Cookson, B.T.5
Logan, S.M.6
Aderem, A.7
-
63
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
Mariathasan, S., K. Newton, D. M. Monack, D. Vucic, D. M. French, W. P. Lee, M. Roose-Girma, S. Erickson, and V. M. Dixit. 2004. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 430: 213-218.
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
Roose-Girma, M.7
Erickson, S.8
Dixit, V.M.9
-
64
-
-
38449115675
-
Altered inflammatory responses in TLR5-deficient mice infected with Legionella pneumophila
-
Hawn, T. R, W. R. Berrington, I. A. Smith, S. Uematsu, S. Akira, A. Aderem, K. D. Smith, and S. J. Skerrett. 2007. Altered inflammatory responses in TLR5-deficient mice infected with Legionella pneumophila. J. Immunol. 179: 6981-6987.
-
(2007)
J. Immunol.
, vol.179
, pp. 6981-6987
-
-
Hawn, T.R.1
Berrington, W.R.2
Smith, I.A.3
Uematsu, S.4
Akira, S.5
Aderem, A.6
Smith, K.D.7
Skerrett, S.J.8
-
65
-
-
77649241461
-
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
-
Miao, E. A., D. P. Mao, N. Yudkovsky, R. Bonneau, C. G. Lorang, S. E. Warren, I. A. Leaf, and A. Aderem. 2010. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc. Natl. Acad. Sci. USA 107: 3076-3080.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 3076-3080
-
-
Miao, E.A.1
Mao, D.P.2
Yudkovsky, N.3
Bonneau, R.4
Lorang, C.G.5
Warren, S.E.6
Leaf, I.A.7
Aderem, A.8
-
66
-
-
52549099416
-
Critical function for Naip5 in inflammasome activation by a conserved carboxyterminal domain of flagellin
-
Lightfield, K. L., J. Persson, S. W. Brubaker, C. E. Witte, J. von Moltke, E. A. Dunipace, T. Henry, Y.-H. Sun, D. Cado, W. F. Dietrich, et al. 2008. Critical function for Naip5 in inflammasome activation by a conserved carboxyterminal domain of flagellin. Nat. Immunol. 9: 1171-1178.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1171-1178
-
-
Lightfield, K.L.1
Persson, J.2
Brubaker, S.W.3
Witte, C.E.4
Von Moltke, J.5
Dunipace, E.A.6
Henry, T.7
Sun, Y.-H.8
Cado, D.9
Dietrich, W.F.10
-
67
-
-
0028920863
-
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme
-
Kuida, K., J. A. Lippke, G. Ku, M. W. Harding, D. J. Livingston, M. S. Su, and R. A. Flavell. 1995. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 267: 2000-2003.
-
(1995)
Science
, vol.267
, pp. 2000-2003
-
-
Kuida, K.1
Lippke, J.A.2
Ku, G.3
Harding, M.W.4
Livingston, D.J.5
Su, M.S.6
Flavell, R.A.7
-
68
-
-
0032127279
-
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function
-
Adachi, O., T. Kawai, K. Takeda, M. Matsumoto, H. Tsutsui, M. Sakagami, K. Nakanishi, and S. Akira. 1998. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity 9: 143-150.
-
(1998)
Immunity
, vol.9
, pp. 143-150
-
-
Adachi, O.1
Kawai, T.2
Takeda, K.3
Matsumoto, M.4
Tsutsui, H.5
Sakagami, M.6
Nakanishi, K.7
Akira, S.8
-
69
-
-
33746161021
-
Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells
-
Uematsu, S., M. H. Jang, N. Chevrier, Z. Guo, Y. Kumagai, M. Yamamoto, H. Kato, N. Sougawa, H. Matsui, H. Kuwata, et al. 2006. Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells. Nat. Immunol. 7: 868-874.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 868-874
-
-
Uematsu, S.1
Jang, M.H.2
Chevrier, N.3
Guo, Z.4
Kumagai, Y.5
Yamamoto, M.6
Kato, H.7
Sougawa, N.8
Matsui, H.9
Kuwata, H.10
-
70
-
-
47249095741
-
Both radioresistant and hemopoietic cells promote innate and adaptive immune responses to flagellin
-
Sanders, C. J., D. A. Moore, I. R. Williams, 3rd, and A. T. Gewirtz. 2008. Both radioresistant and hemopoietic cells promote innate and adaptive immune responses to flagellin. J. Immunol. 180: 7184-7192.
-
(2008)
J. Immunol.
, vol.180
, pp. 7184-7192
-
-
Sanders, C.J.1
Moore, D.A.2
Williams III, I.R.3
Gewirtz, A.T.4
-
71
-
-
84868089513
-
Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica
-
Hajjar, A. M., R. K. Ernst, E. S. Fortuno, III, A. S. Brasfield, C. S. Yam, L. A. Newlon, T. R. Kollmann, S. I. Miller, and C. B. Wilson. 2012. Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica. PLoS Pathog. 8: e1002963.
-
(2012)
PLoS Pathog
, vol.8
-
-
Hajjar, A.M.1
Ernst, R.K.2
Fortuno III, E.S.3
Brasfield, A.S.4
Yam, C.S.5
Newlon, L.A.6
Kollmann, T.R.7
Miller, S.I.8
Wilson, C.B.9
-
72
-
-
84871150034
-
+ regulatory T cell and IgA responses in the mesenteric lymph node
-
+ regulatory T cell and IgA responses in the mesenteric lymph node. J. Immunol. 189: 5745-5754.
-
(2012)
J. Immunol.
, vol.189
, pp. 5745-5754
-
-
Flores-Langarica, A.1
Marshall, J.L.2
Hitchcock, J.3
Cook, C.4
Jobanputra, J.5
Bobat, S.6
Ross, E.A.7
Coughlan, R.E.8
Henderson, I.R.9
Uematsu, S.10
Akira, S.11
Cunningham, A.F.12
-
73
-
-
45549099429
-
Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5
-
Uematsu, S., K. Fujimoto, M. H. Jang, B.-G. Yang, Y.-J. Jung, M. Nishiyama, S. Sato, T. Tsujimura, M. Yamamoto, Y. Yokota, et al. 2008. Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5. Nat. Immunol. 9: 769-776.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 769-776
-
-
Uematsu, S.1
Fujimoto, K.2
Jang, M.H.3
Yang, B.-G.4
Jung, Y.-J.5
Nishiyama, M.6
Sato, S.7
Tsujimura, T.8
Yamamoto, M.9
Yokota, Y.10
-
74
-
-
0037228017
-
Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila
-
Diez, E., S.-H. Lee, S. Gauthier, Z. Yaraghi, M. Tremblay, S. Vidal, and P. Gros. 2003. Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila. Nat. Genet. 33: 55-60.
-
(2003)
Nat. Genet.
, vol.33
, pp. 55-60
-
-
Diez, E.1
Lee, S.-H.2
Gauthier, S.3
Yaraghi, Z.4
Tremblay, M.5
Vidal, S.6
Gros, P.7
-
75
-
-
84856988610
-
Simultaneous targeting of toll- and nod-like receptors induces effective tumor-specific immune responses
-
Garaude, J., A. Kent, N. van Rooijen, and J. M. Blander. 2012. Simultaneous targeting of toll- and nod-like receptors induces effective tumor-specific immune responses. Sci. Transl. Med. 4: 20ra16.
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Garaude, J.1
Kent, A.2
Van Rooijen, N.3
Blander, J.M.4
-
76
-
-
48549085489
-
Flagellin treatment protects against chemicals, bacteria, viruses, and radiation
-
Vijay-Kumar, M., J. Aitken, C. Sanders, A. Frias, V. Sloane, J. Xu, A. Neish, M. Rojas, and A. Gewirtz. 2008. Flagellin treatment protects against chemicals, bacteria, viruses, and radiation. J. Immunol. 180: 8280-8285.
-
(2008)
J. Immunol.
, vol.180
, pp. 8280-8285
-
-
Vijay-Kumar, M.1
Aitken, J.2
Sanders, C.3
Frias, A.4
Sloane, V.5
Xu, J.6
Neish, A.7
Rojas, M.8
Gewirtz, A.9
-
77
-
-
81455141945
-
Flagellin, a TLR5 agonist, reduces graft-versus-host disease in allogeneic hematopoietic stem cell transplantation recipients while enhancing antiviral immunity
-
Hossain, M. S., D. L. Jaye, B. P. Pollack, A. B. Farris, M. L. Tselanyane, E. David, J. D. Roback, A. T. Gewirtz, and E. K. Waller. 2011. Flagellin, a TLR5 agonist, reduces graft-versus-host disease in allogeneic hematopoietic stem cell transplantation recipients while enhancing antiviral immunity. J. Immunol. 187: 5130-5140.
-
(2011)
J. Immunol.
, vol.187
, pp. 5130-5140
-
-
Hossain, M.S.1
Jaye, D.L.2
Pollack, B.P.3
Farris, A.B.4
Tselanyane, M.L.5
David, E.6
Roback, J.D.7
Gewirtz, A.T.8
Waller, E.K.9
-
78
-
-
0037138841
-
Functional human NAIP promoter transcription regulatory elements for the NAIP and PsiNAIP genes
-
Xu, M., T. Okada, H. Sakai, N. Miyamoto, Y. Yanagisawa, A. E. MacKenzie, S. Hadano, and J. E. Ikeda. 2002. Functional human NAIP promoter transcription regulatory elements for the NAIP and PsiNAIP genes. Biochim. Biophys. Acta 1574: 35-50.
-
(2002)
Biochim. Biophys. Acta
, vol.1574
, pp. 35-50
-
-
Xu, M.1
Okada, T.2
Sakai, H.3
Miyamoto, N.4
Yanagisawa, Y.5
MacKenzie, A.E.6
Hadano, S.7
Ikeda, J.E.8
-
79
-
-
66849142132
-
A novel protein isoform of the multicopy human NAIP gene derives from intragenic Alu SINE promoters
-
Romanish, M. T., H. Nakamura, C. B. Lai, Y. Wang, and D. L. Mager. 2009. A novel protein isoform of the multicopy human NAIP gene derives from intragenic Alu SINE promoters. PLoS ONE 4: e5761.
-
(2009)
PLoS ONE
, vol.4
-
-
Romanish, M.T.1
Nakamura, H.2
Lai, C.B.3
Wang, Y.4
Mager, D.L.5
-
80
-
-
45549092412
-
NAIP and Ipaf control Legionella pneumophila replication in human cells
-
Vinzing, M., J. Eitel, J. Lippmann, A. Hocke, J. Zahlten, H. Slevogt, P. N'Guessan, S. Günther, B. Schmeck, S. Hippenstiel, et al. 2008. NAIP and Ipaf control Legionella pneumophila replication in human cells. J. Immunol. 180: 6808-6815.
-
(2008)
J. Immunol.
, vol.180
, pp. 6808-6815
-
-
Vinzing, M.1
Eitel, J.2
Lippmann, J.3
Hocke, A.4
Zahlten, J.5
Slevogt, H.6
N'Guessan, P.7
Günther, S.8
Schmeck, B.9
Hippenstiel, S.10
-
81
-
-
84856331769
-
Population variation in NAIP functional copy number confers increased cell death upon Legionella pneumophila infection
-
Boniotto, M., L. Tailleux, M. Lomma, B. Gicquel, C. Buchrieser, S. Garcia, and L. Quintana-Murci. 2012. Population variation in NAIP functional copy number confers increased cell death upon Legionella pneumophila infection. Hum. Immunol. 73: 196-200.
-
(2012)
Hum. Immunol.
, vol.73
, pp. 196-200
-
-
Boniotto, M.1
Tailleux, L.2
Lomma, M.3
Gicquel, B.4
Buchrieser, C.5
Garcia, S.6
Quintana-Murci, L.7
-
82
-
-
10744226016
-
A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease
-
Hawn, T. R., A. Verbon, K. D. Lettinga, L. P. Zhao, S. S. Li, R. J. Laws, S. J. Skerrett, B. Beutler, L. Schroeder, A. Nachman, et al. 2003. A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease. J. Exp. Med. 198: 1563-1572.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1563-1572
-
-
Hawn, T.R.1
Verbon, A.2
Lettinga, K.D.3
Zhao, L.P.4
Li, S.S.5
Laws, R.J.6
Skerrett, S.J.7
Beutler, B.8
Schroeder, L.9
Nachman, A.10
-
83
-
-
84868028801
-
A mouse model of Salmonella typhi infection
-
Mathur, R., H. Oh, D. Zhang, S.-G. Park, J. Seo, A. Koblansky, M. S. Hayden, and S. Ghosh. 2012. A mouse model of Salmonella typhi infection. Cell 151: 590-602.
-
(2012)
Cell
, vol.151
, pp. 590-602
-
-
Mathur, R.1
Oh, H.2
Zhang, D.3
Park, S.-G.4
Seo, J.5
Koblansky, A.6
Hayden, M.S.7
Ghosh, S.8
-
84
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi, O., and S. Akira. 2010. Pattern recognition receptors and inflammation. Cell 140: 805-820.
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
85
-
-
34247566510
-
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
-
O'Neill, L. A., and A. G. Bowie. 2007. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat. Rev. Immunol. 7: 353-364.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 353-364
-
-
O'Neill, L.A.1
Bowie, A.G.2
-
86
-
-
80051765668
-
Innate responses to Toxoplasma gondii in mice and humans
-
Pifer, R., and F. Yarovinsky. 2011. Innate responses to Toxoplasma gondii in mice and humans. Trends Parasitol. 27: 388-393.
-
(2011)
Trends Parasitol
, vol.27
, pp. 388-393
-
-
Pifer, R.1
Yarovinsky, F.2
-
87
-
-
0015094677
-
The relationship between antigenic structure and the requirement for thymus-derived cells in the immune response
-
Feldmann, M., and A. Easten. 1971. The relationship between antigenic structure and the requirement for thymus-derived cells in the immune response. J. Exp. Med. 134: 103-119.
-
(1971)
J. Exp. Med.
, vol.134
, pp. 103-119
-
-
Feldmann, M.1
Easten, A.2
-
88
-
-
0015323509
-
Induction of immunity and tolerance in vitro by hapten protein conjugates. I. The relationship between the degree of hapten conjugation and the immunogenicity of dinitrophenylated polymerized flagellin
-
Feldmann, M. 1972. Induction of immunity and tolerance in vitro by hapten protein conjugates. I. The relationship between the degree of hapten conjugation and the immunogenicity of dinitrophenylated polymerized flagellin. J. Exp. Med. 135: 735-753.
-
(1972)
J. Exp. Med.
, vol.135
, pp. 735-753
-
-
Feldmann, M.1
-
89
-
-
0014957255
-
Induction of immunity and tolerance in vitro in the absence of phagocytic cells
-
Diener, E., K. Shortman, and P. Russell. 1970. Induction of immunity and tolerance in vitro in the absence of phagocytic cells. Nature 225: 731-732.
-
(1970)
Nature
, vol.225
, pp. 731-732
-
-
Diener, E.1
Shortman, K.2
Russell, P.3
-
90
-
-
0037604765
-
Induction of macrophage nitric oxide production by Gram-negative flagellin involves signaling via heteromeric Toll-like receptor 5/Toll-like receptor 4 complexes
-
Mizel, S. B., A. N. Honko, M. A. Moors, P. S. Smith, and A. P. West. 2003. Induction of macrophage nitric oxide production by Gram-negative flagellin involves signaling via heteromeric Toll-like receptor 5/Toll-like receptor 4 complexes. J. Immunol. 170: 6217-6223.
-
(2003)
J. Immunol.
, vol.170
, pp. 6217-6223
-
-
Mizel, S.B.1
Honko, A.N.2
Moors, M.A.3
Smith, P.S.4
West, A.P.5
-
91
-
-
11144355933
-
Gangliosides act as coreceptors for Salmonella enteritidis FliC and promote FliC induction of human beta-defensin-2 expression in Caco-2 cells
-
Ogushi, K.-i., A. Wada, T. Niidome, T. Okuda, R. Llanes, M. Nakayama, Y. Nishi, H. Kurazono, K. D. Smith, A. Aderem, et al. 2004. Gangliosides act as coreceptors for Salmonella enteritidis FliC and promote FliC induction of human beta-defensin-2 expression in Caco-2 cells. J. Biol. Chem. 279: 12213-12219.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 12213-12219
-
-
Ogushi, K.-I.1
Wada, A.2
Niidome, T.3
Okuda, T.4
Llanes, R.5
Nakayama, M.6
Nishi, Y.7
Kurazono, H.8
Smith, K.D.9
Aderem, A.10
-
92
-
-
84864823652
-
Role of lipid rafts and flagellin in invasion of colonic epithelial cells by Shiga-toxigenic Escherichia coli O113:H21
-
Rogers, T. J., C. M. Thorpe, A. W. Paton, and J. C. Paton. 2012. Role of lipid rafts and flagellin in invasion of colonic epithelial cells by Shiga-toxigenic Escherichia coli O113:H21. Infect. Immun. 80: 2858-2867.
-
(2012)
Infect. Immun.
, vol.80
, pp. 2858-2867
-
-
Rogers, T.J.1
Thorpe, C.M.2
Paton, A.W.3
Paton, J.C.4
-
93
-
-
55349123588
-
Receptorindependent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells
-
Ng, G., K. Sharma, S. M. Ward, M. D. Desrosiers, L. A. Stephens, W. M. Schoel, T. Li, C. A. Lowell, C.-C. Ling, M. W. Amrein, and Y. Shi. 2008. Receptorindependent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells. Immunity 29: 807-818.
-
(2008)
Immunity
, vol.29
, pp. 807-818
-
-
Ng, G.1
Sharma, K.2
Ward, S.M.3
Desrosiers, M.D.4
Stephens, L.A.5
Schoel, W.M.6
Li, T.7
Lowell, C.A.8
Ling, C.-C.9
Amrein, M.W.10
Shi, Y.11
|