Salmonella flagellin-dependent proinflammatory responses are localized to the conserved amino and carboxyl regions of the protein

Journal of Immunology

Volumn 167, Issue 12, 2001, Pages 7009-7016

  Eaves Pyles, T D ^a   Wong, H R ^a   Odoms, K ^a   Pyles, R B ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLAGELLIN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 8; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

AMINO TERMINAL SEQUENCE; ANTIGEN RECOGNITION; ARTICLE; BACTERIAL GENE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN CACO 2; CONTROLLED STUDY; ESCHERICHIA COLI; FLAGELLUM; HUMAN; HUMAN CELL; IMMUNOGENICITY; INFLAMMATION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; SALMONELLA DUBLIN;

EID: 0035892911     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.12.7009     Document Type: Article

References (26)

1. Bacterial modulins: A novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis
2. Release of cytokines induced by Salmonella typhimurium porins
3. Bacterial induction of inducible nitric oxide synthase in cultured human intestinal epithelial cells
4. Bacterial DNA and lipopolysaccharide induce synergistic production of TNF-α through a post-transcriptional mechanism
5. Nitric oxide in the gut
6. Apoptosis: One of the mechanisms that maintains unresponsiveness of the intestinal mucosal immune system
7. Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: IκBα degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunction
8. Role of flagella in pathogenesis of Pseudomonas aeruginosapulmonary infection
9. Salmonella typhi flagella are potent inducers of proinflammatory cytokine secretion by human monocytes
10. High-affinity interaction between Gram-negative flagellin and a cell surface polypeptide results in human monocytes activation
11. Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response
12. The NF-κB and IκB proteins: New discoveries and insights
13. Bacterial invasion is not required for activation of NF-κB in enterocytes
14. Construction of a flagellum -negative mutant of Proteus mirabilis: Effect on internalization by human renal epithelial cells and virulence in a mouse model of ascending urinary tract infection
15. Flagellin gene diversity among Helicobacter pylori strains and IL-8 secretion from gastric epithelial cells
16. Structure of the core and central channel of bacterial flagella
17. Role of the outermost subdomain of Salmonella flagellin in the filament structure revealed by electron microscopy
18. Hypervariable region IV of Salmonella gene fliCd encodes a dominant surface epitope and a stabilizing factor for function flagella
19. Segment IV of a Salmonella flagellin gene specifies flagellar antigen epitopes
20. The symmetrical structure of structural maintenance of chromosome and MukB proteins: Long, antiparallel coiled coils, folded at a flexible hinge
21. Method for the isolation of highly purified Salmonella flagellin
22. Induction and activity of nitric oxide synthase in cultured human intestinal epithelial monolayers
23. The bacterial flagellar cap as the rotary promoter of flagellin self-assembly
24. Flagellin domain that affects H antigenicity of E. coli K-12
25. Immune response to cholera toxin epitope inserted in Salmonella flagella
26. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5