메뉴 건너뛰기




Volumn 30, Issue 40, 2012, Pages 5856-5863

Chimeric flagellin as the self-adjuvanting antigen for the activation of immune response against Helicobacter pylori

Author keywords

Adjuvant; Chimeric protein; Flagellin; Helicobacter pylori; Innate immunity; Toll like receptor 5

Indexed keywords

CHIMERIC FLAGELLIN; CHIMERIC PROTEIN; FLAGELLIN; HELICOBACTER PYLORI VACCINE; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; TOLL LIKE RECEPTOR 5; UNCLASSIFIED DRUG;

EID: 84864822911     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2012.07.011     Document Type: Article
Times cited : (32)

References (40)
  • 1
    • 0025891454 scopus 로고
    • Helicobacter pylori and peptic ulcer disease
    • April (15)
    • Peterson W.L. Helicobacter pylori and peptic ulcer disease. N Engl J Med 1991, 324(April (15)):1043-1048.
    • (1991) N Engl J Med , vol.324 , pp. 1043-1048
    • Peterson, W.L.1
  • 4
    • 0031714446 scopus 로고    scopus 로고
    • Helicobacter pylori infection induces gastric cancer in mongolian gerbils
    • September (3)
    • Watanabe T., Tada M., Nagai H., Sasaki S., Nakao M. Helicobacter pylori infection induces gastric cancer in mongolian gerbils. Gastroenterology 1998, 115(September (3)):642-648.
    • (1998) Gastroenterology , vol.115 , pp. 642-648
    • Watanabe, T.1    Tada, M.2    Nagai, H.3    Sasaki, S.4    Nakao, M.5
  • 5
    • 0027521101 scopus 로고
    • Treatment strategies for Helicobacter pylori infection
    • March (1)
    • Marshall B.J. Treatment strategies for Helicobacter pylori infection. Gastroenterol Clin North Am 1993, 22(March (1)):183-198.
    • (1993) Gastroenterol Clin North Am , vol.22 , pp. 183-198
    • Marshall, B.J.1
  • 6
    • 0344234277 scopus 로고    scopus 로고
    • Helicobacter pylori flagellins have very low intrinsic activity to stimulate human gastric epithelial cells via TLR5
    • December (15)
    • Lee S.K., Stack A., Katzowitsch E., Aizawa S.I., Suerbaum S., Josenhans C. Helicobacter pylori flagellins have very low intrinsic activity to stimulate human gastric epithelial cells via TLR5. Microbes Infect 2003, 5(December (15)):1345-1356.
    • (2003) Microbes Infect , vol.5 , pp. 1345-1356
    • Lee, S.K.1    Stack, A.2    Katzowitsch, E.3    Aizawa, S.I.4    Suerbaum, S.5    Josenhans, C.6
  • 7
    • 2442678870 scopus 로고    scopus 로고
    • Helicobacter pylori flagellin evades toll-like receptor 5-mediated innate immunity
    • May (10)
    • Gewirtz A.T., Yu Y., Krishna U.S., Israel D.A., Lyons S.L., Peek R.M. Helicobacter pylori flagellin evades toll-like receptor 5-mediated innate immunity. J Infect Dis 2004, 189(May (10)):1914-1920.
    • (2004) J Infect Dis , vol.189 , pp. 1914-1920
    • Gewirtz, A.T.1    Yu, Y.2    Krishna, U.S.3    Israel, D.A.4    Lyons, S.L.5    Peek, R.M.6
  • 9
    • 33646014793 scopus 로고    scopus 로고
    • Variation in bacterial flagellins: from sequence to structure
    • April (4)
    • Beatson S.A., Minamino T., Pallen M.J. Variation in bacterial flagellins: from sequence to structure. Trends Microbiol 2006, 14(April (4)):151-155.
    • (2006) Trends Microbiol , vol.14 , pp. 151-155
    • Beatson, S.A.1    Minamino, T.2    Pallen, M.J.3
  • 10
    • 0042238051 scopus 로고    scopus 로고
    • Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy
    • August (6949)
    • Yonekura K., Maki-Yonekura S., Namba K. Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy. Nature 2003, 424(August (6949)):643-650.
    • (2003) Nature , vol.424 , pp. 643-650
    • Yonekura, K.1    Maki-Yonekura, S.2    Namba, K.3
  • 11
    • 42349084254 scopus 로고    scopus 로고
    • Divergence of quaternary structures among bacterial flagellar filaments
    • April (5874)
    • Galkin V.E., Yu X., Bielnicki J., Heuser J., Ewing C.P., Guerry P., et al. Divergence of quaternary structures among bacterial flagellar filaments. Science 2008, 320(April (5874)):382-385.
    • (2008) Science , vol.320 , pp. 382-385
    • Galkin, V.E.1    Yu, X.2    Bielnicki, J.3    Heuser, J.4    Ewing, C.P.5    Guerry, P.6
  • 12
    • 0035868953 scopus 로고    scopus 로고
    • Structure of the bacterial flagellar protofilament and implications for a switch for supercoiling
    • March (6826)
    • Samatey F.A., Imada K., Nagashima S., Vonderviszt F., Kumasaka T., Yamamoto M., et al. Structure of the bacterial flagellar protofilament and implications for a switch for supercoiling. Nature 2001, 410(March (6826)):331-337.
    • (2001) Nature , vol.410 , pp. 331-337
    • Samatey, F.A.1    Imada, K.2    Nagashima, S.3    Vonderviszt, F.4    Kumasaka, T.5    Yamamoto, M.6
  • 13
    • 0033945681 scopus 로고    scopus 로고
    • Enteroaggregative Escherichia coli expresses a novel flagellin that causes IL-8 release from intestinal epithelial cells
    • June (12)
    • Steiner T.S., Nataro J.P., Poteet-Smith C.E., Smith J.A., Guerrant R.L. Enteroaggregative Escherichia coli expresses a novel flagellin that causes IL-8 release from intestinal epithelial cells. J Clin Invest 2000, 105(June (12)):1769-1777.
    • (2000) J Clin Invest , vol.105 , pp. 1769-1777
    • Steiner, T.S.1    Nataro, J.P.2    Poteet-Smith, C.E.3    Smith, J.A.4    Guerrant, R.L.5
  • 14
    • 49649129943 scopus 로고    scopus 로고
    • Deletion of flagellin's hypervariable region abrogates antibody-mediated neutralization and systemic activation of TLR5-dependent immunity
    • August (3)
    • Nempont C., Cayet D., Rumbo M., Bompard C., Villeret V., Sirard J.C. Deletion of flagellin's hypervariable region abrogates antibody-mediated neutralization and systemic activation of TLR5-dependent immunity. J Immunol 2008, 181(August (3)):2036-2043.
    • (2008) J Immunol , vol.181 , pp. 2036-2043
    • Nempont, C.1    Cayet, D.2    Rumbo, M.3    Bompard, C.4    Villeret, V.5    Sirard, J.C.6
  • 15
    • 37449031125 scopus 로고    scopus 로고
    • Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin
    • January (2)
    • Huleatt J.W., Nakaar V., Desai P., Huang Y., Hewitt D., Jacobs A., et al. Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin. Vaccine 2008, 26(January (2)):201-214.
    • (2008) Vaccine , vol.26 , pp. 201-214
    • Huleatt, J.W.1    Nakaar, V.2    Desai, P.3    Huang, Y.4    Hewitt, D.5    Jacobs, A.6
  • 16
    • 33747791726 scopus 로고    scopus 로고
    • Humoral immune response to flagellin requires T cells and activation of innate immunity
    • September (5)
    • Sanders C.J., Yu Y., Moore D.A., Williams I.R., Gewirtz A.T. Humoral immune response to flagellin requires T cells and activation of innate immunity. J Immunol 2006, 177(September (5)):2810-2818.
    • (2006) J Immunol , vol.177 , pp. 2810-2818
    • Sanders, C.J.1    Yu, Y.2    Moore, D.A.3    Williams, I.R.4    Gewirtz, A.T.5
  • 17
    • 77951233298 scopus 로고    scopus 로고
    • Reconstitution of a functional Toll-like receptor 5 binding site in Campylobacter jejuni flagellin
    • April (16)
    • de Zoete M.R., Keestra A.M., Wagenaar J.A., van Putten J.P. Reconstitution of a functional Toll-like receptor 5 binding site in Campylobacter jejuni flagellin. J Biol Chem 2010, 285(April (16)):12149-12158.
    • (2010) J Biol Chem , vol.285 , pp. 12149-12158
    • de Zoete, M.R.1    Keestra, A.M.2    Wagenaar, J.A.3    van Putten, J.P.4
  • 18
    • 33845224163 scopus 로고    scopus 로고
    • Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity
    • January (4)
    • Huleatt J.W., Jacobs A.R., Tang J., Desai P., Kopp E.B., Huang Y., et al. Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity. Vaccine 2007, 25(January (4)):763-775.
    • (2007) Vaccine , vol.25 , pp. 763-775
    • Huleatt, J.W.1    Jacobs, A.R.2    Tang, J.3    Desai, P.4    Kopp, E.B.5    Huang, Y.6
  • 19
    • 0034661646 scopus 로고    scopus 로고
    • Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFN-gamma, gene-deficient mice
    • July (2)
    • Smythies L.E., Waites K.B., Lindsey J.R., Harris P.R., Ghiara P., Smith P.D. Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFN-gamma, gene-deficient mice. J Immunol 2000, 165(July (2)):1022-1029.
    • (2000) J Immunol , vol.165 , pp. 1022-1029
    • Smythies, L.E.1    Waites, K.B.2    Lindsey, J.R.3    Harris, P.R.4    Ghiara, P.5    Smith, P.D.6
  • 20
    • 77953948201 scopus 로고    scopus 로고
    • A recombinant flagellin-poxvirus fusion protein vaccine elicits complement-dependent protection against respiratory challenge with vaccinia virus in mice
    • April (2)
    • Delaney K.N., Phipps J.P., Johnson J.B., Mizel S.B. A recombinant flagellin-poxvirus fusion protein vaccine elicits complement-dependent protection against respiratory challenge with vaccinia virus in mice. Viral Immunol 2010, 23(April (2)):201-210.
    • (2010) Viral Immunol , vol.23 , pp. 201-210
    • Delaney, K.N.1    Phipps, J.P.2    Johnson, J.B.3    Mizel, S.B.4
  • 21
    • 58149392737 scopus 로고    scopus 로고
    • Flagellin-F1-V fusion protein is an effective plague vaccine in mice and two species of nonhuman primates
    • January (1)
    • Mizel S.B., Graff A.H., Sriranganathan N., Ervin S., Lees C.J., Lively M.O., et al. Flagellin-F1-V fusion protein is an effective plague vaccine in mice and two species of nonhuman primates. Clin Vaccine Immunol 2009, 16(January (1)):21-28.
    • (2009) Clin Vaccine Immunol , vol.16 , pp. 21-28
    • Mizel, S.B.1    Graff, A.H.2    Sriranganathan, N.3    Ervin, S.4    Lees, C.J.5    Lively, M.O.6
  • 22
    • 78650648694 scopus 로고    scopus 로고
    • Flagellin as an adjuvant: cellular mechanisms and potential
    • November (10)
    • Mizel S.B., Bates J.T. Flagellin as an adjuvant: cellular mechanisms and potential. J Immunol 2010, 185(November (10)):5677-5682.
    • (2010) J Immunol , vol.185 , pp. 5677-5682
    • Mizel, S.B.1    Bates, J.T.2
  • 23
    • 69949114443 scopus 로고    scopus 로고
    • Superior efficacy of a recombinant flagellin:H5N1 HA globular head vaccine is determined by the placement of the globular head within flagellin
    • Song L., Zhang Y., Yun N.E., Poussard A.L., Smith J.N., Smith J.K., et al. Superior efficacy of a recombinant flagellin:H5N1 HA globular head vaccine is determined by the placement of the globular head within flagellin. Vaccine 2009, 27(42):5875-5884.
    • (2009) Vaccine , vol.27 , Issue.42 , pp. 5875-5884
    • Song, L.1    Zhang, Y.2    Yun, N.E.3    Poussard, A.L.4    Smith, J.N.5    Smith, J.K.6
  • 24
    • 79961167250 scopus 로고    scopus 로고
    • DNA released from dying host cells mediates aluminum adjuvant activity
    • Marichal T., Ohata K., Bedoret D., Mesnil C., Sabatel C., Kobiyama K., et al. DNA released from dying host cells mediates aluminum adjuvant activity. Nat Med 2011, 17(8):996-1002.
    • (2011) Nat Med , vol.17 , Issue.8 , pp. 996-1002
    • Marichal, T.1    Ohata, K.2    Bedoret, D.3    Mesnil, C.4    Sabatel, C.5    Kobiyama, K.6
  • 25
    • 0029047540 scopus 로고
    • Immunologic adjuvants for modern vaccine formulations
    • May
    • Vogel F.R. Immunologic adjuvants for modern vaccine formulations. Ann N Y Acad Sci 1995, 754(May):153-160.
    • (1995) Ann N Y Acad Sci , vol.754 , pp. 153-160
    • Vogel, F.R.1
  • 26
    • 0029021348 scopus 로고
    • Vaccine strategies: targeting helper T cell responses
    • May
    • Golding B., Scott D.E. Vaccine strategies: targeting helper T cell responses. Ann N Y Acad Sci 1995, 754(May):126-137.
    • (1995) Ann N Y Acad Sci , vol.754 , pp. 126-137
    • Golding, B.1    Scott, D.E.2
  • 27
    • 25444533307 scopus 로고    scopus 로고
    • Cellular mechanisms of the adjuvant activity of the flagellin component FljB of Salmonella enterica Serovar typhimurium to potentiate mucosal and systemic responses
    • October (10)
    • Pino O., Martin M., Michalek S.M. Cellular mechanisms of the adjuvant activity of the flagellin component FljB of Salmonella enterica Serovar typhimurium to potentiate mucosal and systemic responses. Infect Immun 2005, 73(October (10)):6763-6770.
    • (2005) Infect Immun , vol.73 , pp. 6763-6770
    • Pino, O.1    Martin, M.2    Michalek, S.M.3
  • 28
    • 9244249138 scopus 로고    scopus 로고
    • Responses to the soluble flagellar protein FliC are Th2, while those to FliC on Salmonella are Th1
    • November (11)
    • Cunningham A.F., Khan M., Ball J., Toellner K.M., Serre K., Mohr E., et al. Responses to the soluble flagellar protein FliC are Th2, while those to FliC on Salmonella are Th1. Eur J Immunol 2004, 34(November (11)):2986-2995.
    • (2004) Eur J Immunol , vol.34 , pp. 2986-2995
    • Cunningham, A.F.1    Khan, M.2    Ball, J.3    Toellner, K.M.4    Serre, K.5    Mohr, E.6
  • 29
    • 0242580118 scopus 로고    scopus 로고
    • Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos
    • November (10)
    • Agrawal S., Agrawal A., Doughty B., Gerwitz A., Blenis J., Van Dyke T., et al. Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. J Immunol 2003, 171(November (10)):4984-4989.
    • (2003) J Immunol , vol.171 , pp. 4984-4989
    • Agrawal, S.1    Agrawal, A.2    Doughty, B.3    Gerwitz, A.4    Blenis, J.5    Van Dyke, T.6
  • 30
    • 0034775153 scopus 로고    scopus 로고
    • Toll-like receptors control activation of adaptive immune responses
    • October (10)
    • Schnare M., Barton G.M., Holt A.C., Takeda K., Akira S., Medzhitov R. Toll-like receptors control activation of adaptive immune responses. Nat Immunol 2001, 2(October (10)):947-950.
    • (2001) Nat Immunol , vol.2 , pp. 947-950
    • Schnare, M.1    Barton, G.M.2    Holt, A.C.3    Takeda, K.4    Akira, S.5    Medzhitov, R.6
  • 31
    • 45749111446 scopus 로고    scopus 로고
    • Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
    • June (7198)
    • Eisenbarth S.C., Colegio O.R., O'Connor W., Sutterwala F.S., Flavell R.A. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 2008, 453(June (7198)):1122-1126.
    • (2008) Nature , vol.453 , pp. 1122-1126
    • Eisenbarth, S.C.1    Colegio, O.R.2    O'Connor, W.3    Sutterwala, F.S.4    Flavell, R.A.5
  • 32
    • 56149119563 scopus 로고    scopus 로고
    • Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome
    • September (6)
    • Kool M., Pétrilli V., De Smedt T., Rolaz A., Hammad H., van Nimwegen M., et al. Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome. J Immunol 2008, 181(September (6)):3755-3759.
    • (2008) J Immunol , vol.181 , pp. 3755-3759
    • Kool, M.1    Pétrilli, V.2    De Smedt, T.3    Rolaz, A.4    Hammad, H.5    van Nimwegen, M.6
  • 33
    • 47849087075 scopus 로고    scopus 로고
    • Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3
    • July (1)
    • Li H., Willingham S.B., Ting J.P., Re F. Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J Immunol 2008, 181(July (1)):17-21.
    • (2008) J Immunol , vol.181 , pp. 17-21
    • Li, H.1    Willingham, S.B.2    Ting, J.P.3    Re, F.4
  • 34
    • 79954587515 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts regulate the production of prostaglandin in macrophages via NALP3 inflammasome-independent mechanisms
    • April (4)
    • Kuroda E., Ishii K.J., Uematsu S., Ohata K., Coban C., Akira S., et al. Silica crystals and aluminum salts regulate the production of prostaglandin in macrophages via NALP3 inflammasome-independent mechanisms. Immunity 2011, 34(April (4)):514-526.
    • (2011) Immunity , vol.34 , pp. 514-526
    • Kuroda, E.1    Ishii, K.J.2    Uematsu, S.3    Ohata, K.4    Coban, C.5    Akira, S.6
  • 35
    • 79953747554 scopus 로고    scopus 로고
    • Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity
    • April (4)
    • Flach T.L., Ng G., Hari A., Desrosiers M.D., Zhang P., Ward S.M., et al. Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity. Nat Med 2011, 17(April (4)):479-487.
    • (2011) Nat Med , vol.17 , pp. 479-487
    • Flach, T.L.1    Ng, G.2    Hari, A.3    Desrosiers, M.D.4    Zhang, P.5    Ward, S.M.6
  • 36
    • 0030965889 scopus 로고    scopus 로고
    • Novel intranasal immunization techniques for antibody induction and protection of mice against gastric Helicobacter felis infection
    • March (4)
    • Weltzin R., Kleanthous H., Guirakhoo F., Monath T.P., Lee C.K. Novel intranasal immunization techniques for antibody induction and protection of mice against gastric Helicobacter felis infection. Vaccine 1997, 15(March (4)):370-376.
    • (1997) Vaccine , vol.15 , pp. 370-376
    • Weltzin, R.1    Kleanthous, H.2    Guirakhoo, F.3    Monath, T.P.4    Lee, C.K.5
  • 37
    • 0033981934 scopus 로고    scopus 로고
    • In vivo characterization of the murine intranasal model for assessing the immunogenicity of attenuated Salmonella enterica serovar Typhi strains as live mucosal vaccines and as live vectors
    • January (1)
    • Pickett T.E., Pasetti M.F., Galen J.E., Sztein M.B., Levine M.M. In vivo characterization of the murine intranasal model for assessing the immunogenicity of attenuated Salmonella enterica serovar Typhi strains as live mucosal vaccines and as live vectors. Infect Immun 2000, 68(January (1)):205-213.
    • (2000) Infect Immun , vol.68 , pp. 205-213
    • Pickett, T.E.1    Pasetti, M.F.2    Galen, J.E.3    Sztein, M.B.4    Levine, M.M.5
  • 38
    • 0036720237 scopus 로고    scopus 로고
    • Attenuated Salmonella enterica serovar Typhi expressing urease effectively immunizes mice against Helicobacter pylori challenge as part of a heterologous mucosal priming-parenteral boosting vaccination regimen
    • September (9)
    • Londoño-Arcila P., Freeman D., Kleanthous H., O'Dowd A.M., Lewis S., Turner A.K., et al. Attenuated Salmonella enterica serovar Typhi expressing urease effectively immunizes mice against Helicobacter pylori challenge as part of a heterologous mucosal priming-parenteral boosting vaccination regimen. Infect Immun 2002, 70(September (9)):5096-5106.
    • (2002) Infect Immun , vol.70 , pp. 5096-5106
    • Londoño-Arcila, P.1    Freeman, D.2    Kleanthous, H.3    O'Dowd, A.M.4    Lewis, S.5    Turner, A.K.6
  • 39
    • 0033529607 scopus 로고    scopus 로고
    • Immunization of rhesus monkeys with a mucosal prime, parenteral boost strategy protects against infection with Helicobacter pylori
    • August
    • Lee C.K., Soike K., Giannasca P., Hill J., Weltzin R., Kleanthous H., et al. Immunization of rhesus monkeys with a mucosal prime, parenteral boost strategy protects against infection with Helicobacter pylori. Vaccine 1999, 17(August (23-24)):3072-3082.
    • (1999) Vaccine , vol.17 , Issue.23-24 , pp. 3072-3082
    • Lee, C.K.1    Soike, K.2    Giannasca, P.3    Hill, J.4    Weltzin, R.5    Kleanthous, H.6
  • 40
    • 43049166945 scopus 로고    scopus 로고
    • Dynamics of acute and memory mucosal and systemic immune responses against HIV-1 envelope following immunizations through single or combinations of mucosal and systemic routes
    • May (22)
    • Srivastava I., Goodsell A., Zhou F., Sun Y., Burke B., Barnett S., et al. Dynamics of acute and memory mucosal and systemic immune responses against HIV-1 envelope following immunizations through single or combinations of mucosal and systemic routes. Vaccine 2008, 26(May (22)):2796-2806.
    • (2008) Vaccine , vol.26 , pp. 2796-2806
    • Srivastava, I.1    Goodsell, A.2    Zhou, F.3    Sun, Y.4    Burke, B.5    Barnett, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.