The human apoptosis inhibitor NAIP induces pyroptosis in macrophages infected with Legionella pneumophila

Microbes and Infection

Volumn 14, Issue 13, 2012, Pages 1123-1132

  Katagiri, Nanako ^a   Shobuike, Takeo ^a   Chang, Bin ^b   Kukita, Akiko ^a   Miyamoto, Hiroshi ^a  

^a SAGA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Caspases; Cell death; Cellular response; Legionella pneumophila; Macrophage

Indexed keywords

CAMPTOTHECIN; FLAGELLIN; INTERLEUKIN 1BETA CONVERTING ENZYME; NEURONAL APOPTOSIS INHIBITORY PROTEIN;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CYTOTOXICITY; GENOME; HUMAN; HUMAN CELL; LEGIONELLA PNEUMOPHILA; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL;

ANIMALS; APOPTOSIS; CAMPTOTHECIN; CASPASE 1; CASPASE INHIBITORS; CELL DEATH; CELL LINE; CELL SURVIVAL; DNA DAMAGE; ENZYME ACTIVATION; FLAGELLIN; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERLEUKIN-1BETA; LEGIONELLA PNEUMOPHILA; MACROPHAGES; MICE; MICE, INBRED C57BL; NEURONAL APOPTOSIS-INHIBITORY PROTEIN; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS); LEGIONELLA PNEUMOPHILA; MURINAE;

EID: 84868090804     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2012.03.006     Document Type: Article

References (38)

1. Srinivasula S.M., Ashwell J.D. IAPs: what's in a name?. Mol. Cell 2008, 30:123-135.
2. Liston P., Roy N., Tamai K., Lefebvre C., Baird S., Cherton-Horvat G., Farahani R., McLean M., Ikeda J.E., MacKenzie A., Korneluk R.G. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. Nature 1996, 379:349-353.
3. Xu D.G., Crocker S.J., Doucet J.P., St-Jean M., Tamai K., Hakim A.M., Ikeda J.E., Liston P., Thompson C.S., Korneluk R.G., MacKenzie A., Robertson G.S. Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus. Nat. Med. 1997, 3:997-1004.
4. Lamkanfi M., Kanneganti T.D. Caspase-7: a protease involved in apoptosis and inflammation. Int. J. Biochem. Cell Biol. 2010, 42:21-24.
5. Davoodi J., Ghahremani M.H., Es-Haghi A., Mohammad-Gholi A., Mackenzie A. Neuronal apoptosis inhibitory protein, NAIP, is an inhibitor of procaspase-9. Int. J. Biochem. Cell Biol. 2010, 42:958-964.
6. Maier J.K., Lahoua Z., Gendron N.H., Fetni R., Johnston A., Davoodi J., Rasper D., Roy S., Slack R.S., Nicholson D.W., MacKenzie A.E. The neuronal apoptosis inhibitory protein is a direct inhibitor of caspases 3 and 7. J. Neurosci. 2002, 22:2035-2043.
7. Davoodi J., Lin L., Kelly J., Liston P., MacKenzie A.E. Neuronal apoptosis-inhibitory protein does not interact with Smac and requires ATP to bind caspase-9. J. Biol. Chem. 2004, 279:40622-40628.
8. Schroder K., Tschopp J. The inflammasomes. Cell 2010, 140:821-832.
9. Diez E., Lee S.H., Gauthier S., Yaraghi Z., Tremblay M., Vidal S., Gros P. Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila. Nat. Genet. 2003, 33:55-60.
10. Wright E.K., Goodart S.A., Growney J.D., Hadinoto V., Endrizzi M.G., Long E.M., Sadigh K., Abney A.L., Bernstein-Hanley I., Dietrich W.F. Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila. Curr. Biol. 2003, 13:27-36.
11. Diederen B.M. Legionella spp. and legionnaires' disease. J. Infect. 2008, 56:1-12.
12. Nash T.W., Libby D.M., Horwitz M.A. Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines and hydrocortisone. J. Clin. Invest. 1984, 74:771-782.
13. Shin S., Roy C.R. Host cell processes that influence the intracellular survival of Legionella pneumophila. Cell Microbiol. 2008, 10:1209-1220.
14. Ensminger A.W., Isberg R.R. Legionella pneumophila Dot/Icm translocated substrates: a sum of parts. Curr. Opin. Microbiol. 2009, 12:67-73.
15. Zamboni D.S., Kobayashi K.S., Kohlsdorf T., Ogura Y., Long E.M., Vance R.E., Kuida K., Mariathasan S., Dixit V.M., Flavell R.A., Dietrich W.F., Roy C.R. The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nat. Immunol. 2006, 7:318-325.
16. Molofsky A.B., Byrne B.G., Whitfield N.N., Madigan C.A., Fuse E.T., Tateda K., Swanson M.S. Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection. J. Exp. Med. 2006, 203:1093-1104.
17. Ren T., Zamboni D.S., Roy C.R., Dietrich W.F., Vance R.E. Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity. PLoS Pathog. 2006, 2:e18.
18. Lightfield K.L., Persson J., Brubaker S.W., Witte C.E., von Moltke J., Dunipace E.A., Henry T., Sun Y.H., Cado D., Dietrich W.F., Monack D.M., Tsolis R.M., Vance R.E. Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin. Nat. Immunol. 2008, 9:1171-1178.
19. Lightfield K.L., Persson J., Trinidad N.J., Brubaker S.W., Kofoed E.M., Sauer J.D., Dunipace E.A., Warren S.E., Miao E.A., Vance R.E. Differential requirements for NAIP5 in activation of the NLRC4 inflammasome. Infect. Immun. 2011, 79:1606-1614.
20. Labbé K., Saleh M. Cell death in the host response to infection. Cell Death Differ. 2008, 15:1339-1349.
21. Bergsbaken T., Fink S.L., Cookson B.T. Pyroptosis: host cell death and inflammation. Nat. Rev. Microbiol. 2009, 7:99-109.
22. Kofoed E.M., Vance R.E. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 2011, 477:592-595.
23. Zhao Y., Yang J., Shi J., Gong Y.N., Lu Q., Xu H., Liu L., Shao F. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 2011, 477:596-600.
24. Silveira T.N., Zamboni D.S. Pore formation triggered by Legionella spp. is an Nlrc4 inflammasome-dependent host cell response that precedes pyroptosis. Infect. Immun. 2010, 78:1403-1413.
25. Endrizzi M.G., Hadinoto V., Growney J.D., Miller W., Dietrich W.F. Genomic sequence analysis of the mouse Naip gene array. Genome Res. 2000, 10:1095-1102.
26. Götz R., Karch C., Digby M.R., Troppmair J., Rapp U.R., Sendtner M. The neuronal apoptosis inhibitory protein suppresses neuronal differentiation and apoptosis in PC12 cells. Hum. Mol. Genet. 2000, 9:2479-2489.
27. Vinzing M., Eitel J., Lippmann J., Hocke A.C., Zahlten J., Slevogt H., N'guessan P.D., Günther S., Schmeck B., Hippenstiel S., Flieger A., Suttorp N., Opitz B. NAIP and Ipaf control Legionella pneumophila replication in human cells. J. Immunol. 2008, 180:6808-6815.
28. Pearlman E., Jiwa A.H., Engleberg N.C., Eisenstein B.I. Growth of Legionella pneumophila in a human macrophage-like (U937) cell line. Microb. Pathog. 1988, 5:87-95.
29. Abdelaziz D.H., Gavrilin M.A., Akhter A., Caution K., Kotrange S., Khweek A.A., Abdulrahman B.A., Grandhi J., Hassan Z.A., Marsh C., Wewers M.D., Amer A.O. Apoptosis-associated speck-like protein (ASC) controls Legionella pneumophila infection in human monocytes. J. Biol. Chem. 2011, 286:3203-3208.
30. Maier J.K., Balabanian S., Coffill C.R., Stewart A., Pelletier L., Franks D.J., Gendron N.H., MacKenzie A.E. Distribution of neuronal apoptosis inhibitory protein in human tissues. J. Histochem. Cytochem. 2007, 55:911-923.
31. Miyamoto H., Yoshida S., Taniguchi H., Shuman H.A. Virulence conversion of Legionella pneumophila by conjugal transfer of chromosomal DNA. J. Bacteriol. 2003, 185:6712-6718.
32. Chang B., Kura F., Amemura-Maekawa J., Koizumi N., Watanabe H. Identification of a novel adhesion molecule involved in the virulence of Legionella pneumophila. Infect. Immun. 2005, 73:4272-4280.
33. Pizzolato J.F., Saltz L.B. The camptothecins. Lancet 2003, 361:2235-2242.
34. Means T.K., Hayashi F., Smith K.D., Aderem A., Luster A.D. The Toll-like receptor 5 stimulus bacterial flagellin induces maturation and chemokine production in human dendritic cells. J. Immunol. 2003, 170:5165-5175.
35. Albers U., Reus K., Shuman H.A., Hilbi H. The amoebae plate test implicates a paralogue of lpxB in the interaction of Legionella pneumophila with Acanthamoeba castellanii. Microbiology 2005, 151:167-182.
36. Losick V.P., Stephan K., Smirnova I.I., Isberg R.R., Poltorak A. A hemidominant Naip5 allele in mouse strain MOLF/Ei-derived macrophages restricts Legionella pneumophila intracellular growth. Infect. Immun. 2009, 77:196-204.
37. Poyet J.L., Srinivasula S.M., Tnani M., Razmara M., Fernandes-Alnemri T., Alnemri E.S. Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. J. Biol. Chem. 2001, 276:28309-28313.
38. Boniotto M., Tailleux L., Lomma M., Gicquel B., Buchrieser C., Garcia S., Quintana-Murci L. Population variation in NAIP functional copy number confers increased cell death upon Legionella pneumophila infection. Hum. Immunol. 2012, 73:196-200.