메뉴 건너뛰기




Volumn 35, Issue 3, 2014, Pages 113-118

Therapeutic potential of NaV1.1 activators

Author keywords

cognition; connectivity; epilepsy; interneurons; oscillations; schizophrenia; SCN1A mutations

Indexed keywords

BETA POMPILIDOTOXIN; PYRETHROID; SODIUM CHANNEL NAV1.1; SODIUM CHANNEL STIMULATING AGENT; UNCLASSIFIED DRUG; VERATRIDINE; VOLTAGE GATED SODIUM CHANNEL;

EID: 84896715240     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2013.12.007     Document Type: Review
Times cited : (42)

References (55)
  • 1
    • 11144354817 scopus 로고    scopus 로고
    • Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture
    • C. Chen et al. Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture J. Neurosci. 24 2004 4030 4042
    • (2004) J. Neurosci. , vol.24 , pp. 4030-4042
    • Chen, C.1
  • 2
    • 84887553241 scopus 로고    scopus 로고
    • Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome
    • I. Ogiwara et al. Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome Hum. Mol. Genet. 22 2013 4784 4804
    • (2013) Hum. Mol. Genet. , vol.22 , pp. 4784-4804
    • Ogiwara, I.1
  • 3
    • 0032066007 scopus 로고    scopus 로고
    • Taking the 'idio' out of 'idiosyncratic': Predicting torsades de pointes
    • D.M. Roden Taking the 'idio' out of 'idiosyncratic': predicting torsades de pointes Pacing Clin. Electrophysiol. 21 1998 1029 1034
    • (1998) Pacing Clin. Electrophysiol. , vol.21 , pp. 1029-1034
    • Roden, D.M.1
  • 4
    • 33748115786 scopus 로고    scopus 로고
    • Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy
    • F.H. Yu et al. Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy Nat. Neurosci. 9 2006 1142 1149
    • (2006) Nat. Neurosci. , vol.9 , pp. 1142-1149
    • Yu, F.H.1
  • 5
    • 29844438166 scopus 로고    scopus 로고
    • International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels
    • W.A. Catterall et al. International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels Pharmacol. Rev. 57 2005 397 409
    • (2005) Pharmacol. Rev. , vol.57 , pp. 397-409
    • Catterall, W.A.1
  • 6
    • 84856949002 scopus 로고    scopus 로고
    • Molecular mechanisms of pyrethroid insecticide neurotoxicity: Recent advances
    • D.M. Soderlund Molecular mechanisms of pyrethroid insecticide neurotoxicity: recent advances Arch. Toxicol. 86 2012 165 181
    • (2012) Arch. Toxicol. , vol.86 , pp. 165-181
    • Soderlund, D.M.1
  • 7
    • 79953677853 scopus 로고    scopus 로고
    • Insights into pathophysiology and therapy from a mouse model of Dravet syndrome
    • J.C. Oakley et al. Insights into pathophysiology and therapy from a mouse model of Dravet syndrome Epilepsia 52 Suppl. 2 2011 59 61
    • (2011) Epilepsia , vol.52 , Issue.SUPPL. 2 , pp. 59-61
    • Oakley, J.C.1
  • 8
    • 73349084982 scopus 로고    scopus 로고
    • The SCN1A variant database: A novel research and diagnostic tool
    • L.R. Claes et al. The SCN1A variant database: a novel research and diagnostic tool Hum. Mutat. 30 2009 E904 E920
    • (2009) Hum. Mutat. , vol.30
    • Claes, L.R.1
  • 9
    • 58249130592 scopus 로고    scopus 로고
    • A catalog of SCN1A variants
    • C. Lossin A catalog of SCN1A variants Brain Dev. 31 2009 114 130
    • (2009) Brain Dev. , vol.31 , pp. 114-130
    • Lossin, C.1
  • 10
    • 77954529023 scopus 로고    scopus 로고
    • v1.1 channels and epilepsy
    • v1.1 channels and epilepsy J. Physiol. 588 2010 1849 1859
    • (2010) J. Physiol. , vol.588 , pp. 1849-1859
    • Catterall, W.A.1
  • 11
    • 84865478346 scopus 로고    scopus 로고
    • Dravet syndrome: The main issues
    • R. Guerrini Dravet syndrome: the main issues Eur. J. Paediatr. Neurol. 16 Suppl. 1 2012 S1 S4
    • (2012) Eur. J. Paediatr. Neurol. , vol.16 , Issue.SUPPL. 1
    • Guerrini, R.1
  • 12
    • 84861716984 scopus 로고    scopus 로고
    • Voltage-gated sodium channels at 60: Structure, function and pathophysiology
    • W.A. Catterall Voltage-gated sodium channels at 60: structure, function and pathophysiology J. Physiol. 590 2012 2577 2589
    • (2012) J. Physiol. , vol.590 , pp. 2577-2589
    • Catterall, W.A.1
  • 13
    • 0023784649 scopus 로고
    • Identification of an intracellular peptide segment involved in sodium channel inactivation
    • P.M. Vassilev et al. Identification of an intracellular peptide segment involved in sodium channel inactivation Science 241 1988 1658 1661
    • (1988) Science , vol.241 , pp. 1658-1661
    • Vassilev, P.M.1
  • 14
    • 0022499391 scopus 로고
    • Expression of functional sodium channels from cloned cDNA
    • M. Noda et al. Expression of functional sodium channels from cloned cDNA Nature 322 1986 826 828
    • (1986) Nature , vol.322 , pp. 826-828
    • Noda, M.1
  • 15
    • 0022442442 scopus 로고
    • Messenger RNA coding for only the alpha subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes
    • A.L. Goldin et al. Messenger RNA coding for only the alpha subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes Proc. Natl. Acad. Sci. U.S.A. 83 1986 7503 7507
    • (1986) Proc. Natl. Acad. Sci. U.S.A. , vol.83 , pp. 7503-7507
    • Goldin, A.L.1
  • 16
    • 0026551357 scopus 로고
    • Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel
    • L.L. Isom et al. Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel Science 256 1992 839 842
    • (1992) Science , vol.256 , pp. 839-842
    • Isom, L.L.1
  • 17
    • 0028972374 scopus 로고
    • Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif
    • L.L. Isom et al. Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif Cell 83 1995 433 442
    • (1995) Cell , vol.83 , pp. 433-442
    • Isom, L.L.1
  • 18
    • 77949300922 scopus 로고    scopus 로고
    • Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders
    • M. Mantegazza et al. Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders Lancet Neurol. 9 2010 413 424
    • (2010) Lancet Neurol. , vol.9 , pp. 413-424
    • Mantegazza, M.1
  • 19
    • 48649086182 scopus 로고    scopus 로고
    • + overload and enhanced cell death
    • + overload and enhanced cell death J. Gen. Physiol. 132 2008 199 208
    • (2008) J. Gen. Physiol. , vol.132 , pp. 199-208
    • Hirn, C.1
  • 20
    • 0031978985 scopus 로고    scopus 로고
    • The molecular genetics of the long QT syndrome: Genes causing fainting and sudden death
    • G.M. Vincent The molecular genetics of the long QT syndrome: genes causing fainting and sudden death Annu. Rev. Med. 49 1998 263 274
    • (1998) Annu. Rev. Med. , vol.49 , pp. 263-274
    • Vincent, G.M.1
  • 21
    • 0030608445 scopus 로고    scopus 로고
    • Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs
    • J.A. Black et al. Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs Brain Res. Mol. Brain Res. 43 1996 117 131
    • (1996) Brain Res. Mol. Brain Res. , vol.43 , pp. 117-131
    • Black, J.A.1
  • 22
    • 0030041548 scopus 로고    scopus 로고
    • A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons
    • A.N. Akopian et al. A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons Nature 379 1996 257 262
    • (1996) Nature , vol.379 , pp. 257-262
    • Akopian, A.N.1
  • 23
    • 0032555278 scopus 로고    scopus 로고
    • NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy
    • S.D. Dib-Hajj et al. NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy Proc. Natl. Acad. Sci. U.S.A. 95 1998 8963 8968
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 8963-8968
    • Dib-Hajj, S.D.1
  • 24
    • 0032879716 scopus 로고    scopus 로고
    • Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation
    • G.X. Yan, and C. Antzelevitch Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation Circulation 100 1999 1660 1666
    • (1999) Circulation , vol.100 , pp. 1660-1666
    • Yan, G.X.1    Antzelevitch, C.2
  • 25
    • 33845901486 scopus 로고    scopus 로고
    • An SCN9A channelopathy causes congenital inability to experience pain
    • J.J. Cox et al. An SCN9A channelopathy causes congenital inability to experience pain Nature 444 2006 894 898
    • (2006) Nature , vol.444 , pp. 894-898
    • Cox, J.J.1
  • 26
    • 0037222315 scopus 로고    scopus 로고
    • Sodium channels SCN1A, SCN2A and SCN3A in familial autism
    • L.A. Weiss et al. Sodium channels SCN1A, SCN2A and SCN3A in familial autism Mol. Psychiatry 8 2003 186 194
    • (2003) Mol. Psychiatry , vol.8 , pp. 186-194
    • Weiss, L.A.1
  • 27
    • 23044459961 scopus 로고    scopus 로고
    • Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine
    • M. Dichgans et al. Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine Lancet 366 2005 371 377
    • (2005) Lancet , vol.366 , pp. 371-377
    • Dichgans, M.1
  • 28
    • 79957589237 scopus 로고    scopus 로고
    • Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations
    • B.J. O'Roak et al. Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations Nat. Genet. 43 2011 585 589
    • (2011) Nat. Genet. , vol.43 , pp. 585-589
    • O'Roak, B.J.1
  • 29
    • 84875828570 scopus 로고    scopus 로고
    • Sudden unexpected death in a mouse model of Dravet syndrome
    • F. Kalume et al. Sudden unexpected death in a mouse model of Dravet syndrome J. Clin. Invest. 123 2013 1798 1808
    • (2013) J. Clin. Invest. , vol.123 , pp. 1798-1808
    • Kalume, F.1
  • 30
    • 84866500624 scopus 로고    scopus 로고
    • +/- mice and rescue by enhanced GABA-mediated neurotransmission
    • +/- mice and rescue by enhanced GABA-mediated neurotransmission Nature 489 2012 385 390
    • (2012) Nature , vol.489 , pp. 385-390
    • Han, S.1
  • 31
    • 35348904490 scopus 로고    scopus 로고
    • v1.1 mutant mice: Implications for ataxia in severe myoclonic epilepsy in infancy
    • v1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy J. Neurosci. 27 2007 11065 11074
    • (2007) J. Neurosci. , vol.27 , pp. 11065-11074
    • Kalume, F.1
  • 32
    • 34748912382 scopus 로고    scopus 로고
    • Quantitative analysis of parvalbumin-immunoreactive cells in the human epileptic hippocampus
    • A. Andrioli et al. Quantitative analysis of parvalbumin-immunoreactive cells in the human epileptic hippocampus Neuroscience 149 2007 131 143
    • (2007) Neuroscience , vol.149 , pp. 131-143
    • Andrioli, A.1
  • 33
    • 84883302304 scopus 로고    scopus 로고
    • Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism
    • Y. Liu et al. Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism Ann. Neurol. 74 2013 128 139
    • (2013) Ann. Neurol. , vol.74 , pp. 128-139
    • Liu, Y.1
  • 34
    • 84885724899 scopus 로고    scopus 로고
    • Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons
    • J. Jiao et al. Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons Hum. Mol. Genet. 22 2013 4241 4252
    • (2013) Hum. Mol. Genet. , vol.22 , pp. 4241-4252
    • Jiao, J.1
  • 35
    • 84864704934 scopus 로고    scopus 로고
    • Prognostic, clinical and demographic features in SCN1A mutation-positive Dravet syndrome
    • A. Brunklaus et al. Prognostic, clinical and demographic features in SCN1A mutation-positive Dravet syndrome Brain 135 2012 2329 2336
    • (2012) Brain , vol.135 , pp. 2329-2336
    • Brunklaus, A.1
  • 36
    • 84876317530 scopus 로고    scopus 로고
    • Focal Scn1a knockdown induces cognitive impairment without seizures
    • A.C. Bender et al. Focal Scn1a knockdown induces cognitive impairment without seizures Neurobiol. Dis. 54 2013 297 307
    • (2013) Neurobiol. Dis. , vol.54 , pp. 297-307
    • Bender, A.C.1
  • 37
    • 79151482325 scopus 로고    scopus 로고
    • A genome-wide survey of human short-term memory
    • A. Papassotiropoulos et al. A genome-wide survey of human short-term memory Mol. Psychiatry 16 2011 184 192
    • (2011) Mol. Psychiatry , vol.16 , pp. 184-192
    • Papassotiropoulos, A.1
  • 38
    • 84860334015 scopus 로고    scopus 로고
    • Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model
    • L. Verret et al. Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model Cell 149 2012 708 721
    • (2012) Cell , vol.149 , pp. 708-721
    • Verret, L.1
  • 39
    • 79953129279 scopus 로고    scopus 로고
    • v1.1 levels in BACE1-null mice
    • v1.1 levels in BACE1-null mice J. Biol. Chem. 286 2011 8106 8116
    • (2011) J. Biol. Chem. , vol.286 , pp. 8106-8116
    • Kim, D.Y.1
  • 40
    • 34347394695 scopus 로고    scopus 로고
    • BACE1 regulates voltage-gated sodium channels and neuronal activity
    • D.Y. Kim et al. BACE1 regulates voltage-gated sodium channels and neuronal activity Nat. Cell Biol. 9 2007 755 764
    • (2007) Nat. Cell Biol. , vol.9 , pp. 755-764
    • Kim, D.Y.1
  • 41
    • 84860122481 scopus 로고    scopus 로고
    • A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior
    • M. Carlen et al. A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior Mol. Psychiatry 17 2012 537 548
    • (2012) Mol. Psychiatry , vol.17 , pp. 537-548
    • Carlen, M.1
  • 42
    • 33846849432 scopus 로고    scopus 로고
    • Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior
    • E.C. Fuchs et al. Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior Neuron 53 2007 591 604
    • (2007) Neuron , vol.53 , pp. 591-604
    • Fuchs, E.C.1
  • 43
    • 0037705995 scopus 로고    scopus 로고
    • Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia
    • T. Hashimoto et al. Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia J. Neurosci. 23 2003 6315 6326
    • (2003) J. Neurosci. , vol.23 , pp. 6315-6326
    • Hashimoto, T.1
  • 44
    • 40349106017 scopus 로고    scopus 로고
    • Modelling prefrontal cortex deficits in schizophrenia: Implications for treatment
    • J.A. Pratt et al. Modelling prefrontal cortex deficits in schizophrenia: implications for treatment Br. J. Pharmacol. 153 Suppl. 1 2008 S465 S470
    • (2008) Br. J. Pharmacol. , vol.153 , Issue.SUPPL. 1
    • Pratt, J.A.1
  • 45
    • 0032744393 scopus 로고    scopus 로고
    • Alterations in chandelier neuron axon terminals in the prefrontal cortex of schizophrenic subjects
    • J.N. Pierri et al. Alterations in chandelier neuron axon terminals in the prefrontal cortex of schizophrenic subjects Am. J. Psychiatry 156 1999 1709 1719
    • (1999) Am. J. Psychiatry , vol.156 , pp. 1709-1719
    • Pierri, J.N.1
  • 46
    • 84886952151 scopus 로고    scopus 로고
    • A review of gamma oscillations in healthy subjects and in cognitive impairment
    • E. Basar A review of gamma oscillations in healthy subjects and in cognitive impairment Int. J. Psychophysiol. 90 2013 11 117
    • (2013) Int. J. Psychophysiol. , vol.90 , pp. 11-117
    • Basar, E.1
  • 47
    • 33846513431 scopus 로고    scopus 로고
    • Voltage-gated ion channels and gating modifier toxins
    • W.A. Catterall et al. Voltage-gated ion channels and gating modifier toxins Toxicon 49 2007 124 141
    • (2007) Toxicon , vol.49 , pp. 124-141
    • Catterall, W.A.1
  • 48
    • 0032489951 scopus 로고    scopus 로고
    • Veratridine-treated brain slices: A cellular model for epileptiform activity
    • S. Otoom et al. Veratridine-treated brain slices: a cellular model for epileptiform activity Brain Res. 789 1998 150 156
    • (1998) Brain Res. , vol.789 , pp. 150-156
    • Otoom, S.1
  • 49
    • 0037008382 scopus 로고    scopus 로고
    • Differential effects of novel wasp toxin on rat hippocampal interneurons
    • T. Miyawaki et al. Differential effects of novel wasp toxin on rat hippocampal interneurons Neurosci. Lett. 328 2002 25 28
    • (2002) Neurosci. Lett. , vol.328 , pp. 25-28
    • Miyawaki, T.1
  • 50
    • 84866754503 scopus 로고    scopus 로고
    • Advances in targeting voltage-gated sodium channels with small molecules
    • A. Nardi et al. Advances in targeting voltage-gated sodium channels with small molecules ChemMedChem 7 2012 1712 1740
    • (2012) ChemMedChem , vol.7 , pp. 1712-1740
    • Nardi, A.1
  • 51
    • 70350547576 scopus 로고    scopus 로고
    • Subtype-selective targeting of voltage-gated sodium channels
    • S. England, and M.J. de Groot Subtype-selective targeting of voltage-gated sodium channels Br. J. Pharmacol. 158 2009 1413 1425
    • (2009) Br. J. Pharmacol. , vol.158 , pp. 1413-1425
    • England, S.1    De Groot, M.J.2
  • 52
    • 0018349527 scopus 로고
    • The steady state TTX-sensitive ('window') sodium current in cardiac Purkinje fibres
    • D. Attwell et al. The steady state TTX-sensitive ('window') sodium current in cardiac Purkinje fibres Pflugers Arch. 379 1979 137 142
    • (1979) Pflugers Arch. , vol.379 , pp. 137-142
    • Attwell, D.1
  • 53
    • 34249791771 scopus 로고    scopus 로고
    • v1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: A circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation
    • v1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation J. Neurosci. 27 2007 5903 5914
    • (2007) J. Neurosci. , vol.27 , pp. 5903-5914
    • Ogiwara, I.1
  • 54
    • 66649086927 scopus 로고    scopus 로고
    • Driving fast-spiking cells induces gamma rhythm and controls sensory responses
    • J.A. Cardin et al. Driving fast-spiking cells induces gamma rhythm and controls sensory responses Nature 459 2009 663 667
    • (2009) Nature , vol.459 , pp. 663-667
    • Cardin, J.A.1
  • 55
    • 0343362706 scopus 로고    scopus 로고
    • Total number and ratio of excitatory and inhibitory synapses converging onto single interneurons of different types in the CA1 area of the rat hippocampus
    • A.I. Gulyas et al. Total number and ratio of excitatory and inhibitory synapses converging onto single interneurons of different types in the CA1 area of the rat hippocampus J. Neurosci. 19 1999 10082 10097
    • (1999) J. Neurosci. , vol.19 , pp. 10082-10097
    • Gulyas, A.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.