Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons

Human Molecular Genetics

Volumn 22, Issue 21, 2013, Pages 4241-4252

  Jiao, Jiao ^b,c   Yang, Yuanyuan ^a,b   Shi, Yiwu ^a   Chen, Jiayu ^b   Gao, Rui ^b   Fan, Yong ^a   Yao, Hui ^b,d   Liao, Weiping ^a   Sun, Xiao Fang ^a   Gao, Shaorong ^b  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

^c BEIJING NORMAL UNIVERSITY   (China)

^d CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; GLUTAMATE DECARBOXYLASE 67; PHENYTOIN; SODIUM CHANNEL; SODIUM CHANNEL NAV1.1;

ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG RESPONSE; ELECTROPHYSIOLOGY; EPILEPTIC DISCHARGE; EVOKED RESPONSE; FEBRILE CONVULSION; FIBROBLAST CULTURE; GLUTAMATERGIC NERVE CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; KARYOTYPING; MEMBRANE STEADY POTENTIAL; MICROARRAY ANALYSIS; MUTATIONAL ANALYSIS; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE CELL EXCITABILITY; NERVE POTENTIAL; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SEVERE MYOCLONIC EPILEPSY IN INFANCY; SKIN FIBROBLAST; SODIUM CURRENT; TERATOMA;

ACTION POTENTIALS; ANTICONVULSANTS; CELL DIFFERENTIATION; CELL LINE; EPILEPSIES, MYOCLONIC; GENE EXPRESSION PROFILING; GENETIC VARIATION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; KARYOTYPE; MUTATION, MISSENSE; NAV1.1 VOLTAGE-GATED SODIUM CHANNEL; NEUROGENESIS; NEURONS; PHENYTOIN; SEIZURES, FEBRILE;

EID: 84885724899     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt275     Document Type: Article

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