Caspase-1 has both proinflammatory and regulatory properties in helicobacter infections, which are differentially mediated by its substrates IL-1β and IL-18

Journal of Immunology

Volumn 188, Issue 8, 2012, Pages 3594-3602

  Hitzler, Iris ^a   Sayi, Ayca ^a   Kohler, Esther ^a   Engler, Daniela B ^a   Koch, Katrin N ^a   Hardt, Wolf Dietrich ^b   Müller, Anne ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

HELICOBACTER PYLORI VACCINE; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME SUBSTRATE; EXPERIMENTAL INFECTION; GASTRITIS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; IMMUNITY; IMMUNOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFECTION CONTROL; INFLAMMATION; MOUSE; NONHUMAN; PRECANCER; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STOMACH CANCER; STOMACH DISEASE; TH1 CELL; TH17 CELL;

ADAPTIVE IMMUNITY; ANIMALS; BACTERIAL VACCINES; CASPASE 1; DISEASE MODELS, ANIMAL; GASTRITIS; GENE EXPRESSION REGULATION; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; INTERLEUKIN-18; INTERLEUKIN-1BETA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, INTERLEUKIN-1; SIGNAL TRANSDUCTION; STOMACH; STOMACH NEOPLASMS; TH1 CELLS; TH17 CELLS; VACCINATION;

EID: 84860342710     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1103212     Document Type: Article

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