Pannexin-1-dependent caspase-1 activation and secretion of IL-1β is regulated by zinc

European Journal of Immunology

Volumn 39, Issue 2, 2009, Pages 352-358

  Brough, David ^a   Pelegrin, Pablo ^a   Rothwell, Nancy J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Caspase 1; IL 1; Inflammation; Macrophage; Zinc

Indexed keywords

ADENOSINE TRIPHOSPHATE; CELL PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; N,N,N',N' TETRAKIS(2 PYRIDYLMETHYL)ETHYLENEDIAMINE; NIGERICIN; PANNEXIN 1; PURINERGIC P2X7 RECEPTOR; UNCLASSIFIED DRUG; ZINC; ETHYLENEDIAMINE DERIVATIVE; GAP JUNCTION PROTEIN; N,N,N',N'-TETRAKIS(2-PYRIDYLMETHYL)ETHYLENEDIAMINE; NERVE PROTEIN; PANX1 PROTEIN, MOUSE; PURINERGIC P2 RECEPTOR;

ANIMAL CELL; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INFLAMMATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; ZINC METABOLISM; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; DRUG EFFECT; IMMUNOLOGY; METABOLISM;

ANIMALS; CASPASE 1; CELLS, CULTURED; CONNEXINS; ENZYME ACTIVATION; ETHYLENEDIAMINES; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; RECEPTORS, PURINERGIC P2; ZINC;

EID: 60749110379     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838843     Document Type: Article

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