메뉴 건너뛰기




Volumn 192, Issue 5, 2014, Pages 2305-2314

Upregulation of grail is associated with impaired CD4 T cell proliferation in sepsis

Author keywords

[No Author keywords available]

Indexed keywords

GENE RELATED TO ANERGY IN LYMPHOCYTE PROTEIN; INTERLEUKIN 12; RECOMBINANT PROTEIN; RING FINGER PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84896535128     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1302160     Document Type: Article
Times cited : (30)

References (50)
  • 1
    • 84874509753 scopus 로고    scopus 로고
    • Current trends in inflammatory and immunomodulatory mediators in sepsis
    • Aziz, M., A. Jacob, W. L. Yang, A. Matsuda, and P. Wang. 2013. Current trends in inflammatory and immunomodulatory mediators in sepsis. J. Leukoc. Biol. 93: 329-342.
    • (2013) J. Leukoc. Biol , Issue.93 , pp. 329-342
    • Aziz, M.1    Jacob, A.2    Yang, W.L.3    Matsuda, A.4    Wang, P.5
  • 2
    • 84874256945 scopus 로고    scopus 로고
    • Immunosuppression in sepsis: A novel understanding of the disorder and a new therapeutic approach
    • Hotchkiss, R. S., G. Monneret, and D. Payen. 2013. Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach. Lancet Infect. Dis. 13: 260-268.
    • (2013) Lancet Infect. Dis , Issue.13 , pp. 260-268
    • Hotchkiss, R.S.1    Monneret, G.2    Payen, D.3
  • 6
    • 77951084017 scopus 로고    scopus 로고
    • Impaired cd4+ t-cell proliferation and effector function correlates with repressive histone methylation events in a mouse model of severe sepsis
    • Carson, W. F., IV, K. A. Cavassani, T. Ito, M. Schaller, M. Ishii, Y. Dou, and S. L. Kunkel. 2010. Impaired CD4+ T-cell proliferation and effector function correlates with repressive histone methylation events in a mouse model of severe sepsis. Eur. J. Immunol. 40: 998-1010.
    • (2010) Eur J. Immunol , Issue.40 , pp. 998-1010
    • Carson, W.F.1    Cavassani IV, K.A.2    Ito, T.3    Schaller, M.4    Ishii, M.5    Dou, Y.6    Kunkel, S.L.7
  • 8
    • 34547222902 scopus 로고    scopus 로고
    • Molecular mechanisms of cd4+ t-cell anergy
    • Fathman, C. G., and N. B. Lineberry. 2007. Molecular mechanisms of CD4+ T-cell anergy. Nat. Rev. Immunol. 7: 599-609.
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 599-609
    • Fathman, C.G.1    Lineberry, N.B.2
  • 9
    • 74049160009 scopus 로고    scopus 로고
    • Mechanisms maintaining peripheral tolerance
    • Mueller, D. L. 2010. Mechanisms maintaining peripheral tolerance. Nat. Immunol. 11: 21-27.
    • (2010) Nat. Immunol , Issue.11 , pp. 21-27
    • Mueller, D.L.1
  • 11
    • 0347756795 scopus 로고    scopus 로고
    • T-cell anergy: From phenotype to genotype and back
    • Seroogy, C. M., and C. G. Fathman. 2003. T-cell anergy: from phenotype to genotype and back. Immunol. Res. 28: 255-264.
    • (2003) Immunol. Res , vol.28 , pp. 255-264
    • Seroogy, C.M.1    Fathman, C.G.2
  • 12
    • 4644285392 scopus 로고    scopus 로고
    • E3 ubiquitin ligases as t cell anergy factors
    • Mueller, D. L. 2004. E3 ubiquitin ligases as T cell anergy factors. Nat. Immunol. 5: 883-890.
    • (2004) Nat. Immunol , vol.5 , pp. 883-890
    • Mueller, D.L.1
  • 14
    • 2942707976 scopus 로고    scopus 로고
    • The gene related to anergy in lymphocytes, an e3 ubiquitin ligase, is necessary for anergy induction in cd4 t cells
    • Seroogy, C. M., L. Soares, E. A. Ranheim, L. Su, C. Holness, D. Bloom, and C. G. Fathman. 2004. The gene related to anergy in lymphocytes, an E3 ubiquitin ligase, is necessary for anergy induction in CD4 T cells. J. Immunol. 173: 79-85.
    • (2004) J. Immunol , vol.173 , pp. 79-85
    • Seroogy, C.M.1    Soares, L.2    Ranheim, E.A.3    Su, L.4    Holness, C.5    Bloom, D.6    Fathman, C.G.7
  • 15
    • 70349741085 scopus 로고    scopus 로고
    • E3 ubiquitin ligase grail controls primary t cell activation and oral tolerance
    • Kriegel, M. A., C. Rathinam, and R. A. Flavell. 2009. E3 ubiquitin ligase GRAIL controls primary T cell activation and oral tolerance. Proc. Natl. Acad. Sci. USA 106: 16770-16775.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 16770-16775
    • Kriegel, M.A.1    Rathinam, C.2    Flavell, R.A.3
  • 16
    • 70350559218 scopus 로고    scopus 로고
    • Naive cd4 t cell proliferation is controlled by mammalian target of rapamycin regulation of grail expression
    • Lin, J. T., N. B. Lineberry, M. G. Kattah, L. L. Su, P. J. Utz, C. G. Fathman, and L. Wu. 2009. Naive CD4 T cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression. J. Immunol. 182: 5919-5928.
    • (2009) J. Immunol , vol.182 , pp. 5919-5928
    • Lin, J.T.1    Lineberry, N.B.2    Kattah, M.G.3    Su, L.L.4    Utz, P.J.5    Fathman, C.G.6    Wu, L.7
  • 17
    • 77953289183 scopus 로고    scopus 로고
    • The e3 ubiquitin ligase grail regulates t cell tolerance and regulatory t cell function by mediating t cell receptor-cd3 degradation
    • Nurieva, R. I., S. Zheng, W. Jin, Y. Chung, Y. Zhang, G. J. Martinez, J. M. Reynolds, S. L. Wang, X. Lin, S. C. Sun, et al. 2010. The E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation. Immunity 32: 670-680.
    • (2010) Immunity , vol.32 , pp. 670-680
    • Nurieva, R.I.1    Zheng, S.2    Jin, W.3    Chung, Y.4    Zhang, Y.5    Martinez, G.J.6    Reynolds, J.M.7    Wang, S.L.8    Lin, X.9    Sun, S.C.10
  • 18
    • 78650436475 scopus 로고    scopus 로고
    • Grail: A unique mediator of cd4 t-lymphocyte unresponsiveness
    • Whiting, C. C., L. L. Su, J. T. Lin, and C. G. Fathman. 2011. GRAIL: a unique mediator of CD4 T-lymphocyte unresponsiveness. FEBS J. 278: 47-58.
    • (2011) FEBS J , Issue.278 , pp. 47-58
    • Whiting, C.C.1    Su, L.L.2    Lin, J.T.3    Fathman, C.G.4
  • 19
    • 68949110141 scopus 로고    scopus 로고
    • The transmembrane e3 ligase grail ubiquitinates and degrades cd83 on cd4 t cells
    • Su, L. L., H. Iwai, J. T. Lin, and C. G. Fathman. 2009. The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells. J. Immunol. 183: 438-444.
    • (2009) J. Immunol , vol.183 , pp. 438-444
    • Su, L.L.1    Iwai, H.2    Lin, J.T.3    Fathman, C.G.4
  • 20
    • 49649126399 scopus 로고    scopus 로고
    • Cutting edge: The transmembrane e3 ligase grail ubiquitinates the costimulatory molecule cd40 ligand during the induction of t cell anergy
    • Lineberry, N. B., L. L. Su, J. T. Lin, G. P. Coffey, C. M. Seroogy, and C. G. Fathman. 2008. Cutting edge: the transmembrane E3 ligase GRAIL ubiquitinates the costimulatory molecule CD40 ligand during the induction of T cell anergy. J. Immunol. 181: 1622-1626.
    • (2008) J. Immunol , vol.181 , pp. 1622-1626
    • Lineberry, N.B.1    Su, L.L.2    Lin, J.T.3    Coffey, G.P.4    Seroogy, C.M.5    Fathman, C.G.6
  • 21
    • 83355163383 scopus 로고    scopus 로고
    • Grail (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of arp2/3 subunit 5 and coronin 1a
    • Ichikawa, D., M. Mizuno, T. Yamamura, and S. Miyake. 2011. GRAIL (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3 subunit 5 and coronin 1A. J. Biol. Chem. 286: 43465-43474.
    • (2011) J. Biol. Chem , Issue.286 , pp. 43465-43474
    • Ichikawa, D.1    Mizuno, M.2    Yamamura, T.3    Miyake, S.4
  • 22
    • 71749086535 scopus 로고    scopus 로고
    • Gene related to anergy in lymphocytes (grail) expression in cd4+ t cells impairs actin cytoskeletal organization during t cell/antigen-presenting cell interactions
    • Schartner, J. M., W. T. Simonson, S. A. Wernimont, L. M. Nettenstrom, A. Huttenlocher, and C. M. Seroogy. 2009. Gene related to anergy in lymphocytes (GRAIL) expression in CD4+ T cells impairs actin cytoskeletal organization during T cell/antigen-presenting cell interactions. J. Biol. Chem. 284: 34674-34681.
    • (2009) J. Biol. Chem , vol.284 , pp. 34674-34681
    • Schartner, J.M.1    Simonson, W.T.2    Wernimont, S.A.3    Nettenstrom, L.M.4    Huttenlocher, A.5    Seroogy, C.M.6
  • 23
    • 77952094971 scopus 로고    scopus 로고
    • Immature dendritic cellderived exosomes rescue septic animals via milk fat globule epidermal growth factor-factor viii [corrected]
    • Miksa, M., R. Wu, W. Dong, H. Komura, D. Amin, Y. Ji, Z. Wang, H. Wang, T. S. Ravikumar, K. J. Tracey, and P. Wang. 2009. Immature dendritic cellderived exosomes rescue septic animals via milk fat globule epidermal growth factor-factor VIII [corrected]. J. Immunol. 183: 5983-5990.
    • (2009) J. Immunol , vol.183 , pp. 5983-5990
    • Miksa, M.1    Wu, R.2    Dong, W.3    Komura, H.4    Amin, D.5    Ji, Y.6    Wang, Z.7    Wang, H.8    Ravikumar, T.S.9    Tracey, K.J.10    Wang, P.11
  • 24
    • 84867841791 scopus 로고    scopus 로고
    • Ampk inhibitor compound c suppresses cell proliferation by induction of apoptosis and autophagy in human colorectal cancer cells
    • Yang, W.-L., W. Perillo, D. Liou, P. Marambaud, and P. Wang. 2012. AMPK inhibitor compound C suppresses cell proliferation by induction of apoptosis and autophagy in human colorectal cancer cells. J. Surg. Oncol. 106: 680-688.
    • (2012) J. Surg. Oncol , Issue.106 , pp. 680-688
    • Yang, W.-L.1    Perillo, W.2    Liou, D.3    Marambaud, P.4    Wang, P.5
  • 25
    • 36749041328 scopus 로고    scopus 로고
    • Interleukin 2: From immunostimulation to immunoregulation and back again
    • Bachmann, M. F., and A. Oxenius. 2007. Interleukin 2: from immunostimulation to immunoregulation and back again. EMBO Rep. 8: 1142-1148.
    • (2007) EMBO Rep , vol.8 , pp. 1142-1148
    • Bachmann, M.F.1    Oxenius, A.2
  • 26
    • 0038106475 scopus 로고    scopus 로고
    • Sepsis induces apoptosis and profound depletion of splenic interdigitating and follicular dendritic cells
    • Tinsley, K. W., M. H. Grayson, P. E. Swanson, A. M. Drewry, K. C. Chang, I. E. Karl, and R. S. Hotchkiss. 2003. Sepsis induces apoptosis and profound depletion of splenic interdigitating and follicular dendritic cells. J. Immunol. 171: 909-914.
    • (2003) J. Immunol , vol.171 , pp. 909-914
    • Tinsley, K.W.1    Grayson, M.H.2    Swanson, P.E.3    Drewry, A.M.4    Chang, K.C.5    Karl, I.E.6    Hotchkiss, R.S.7
  • 27
    • 33847011663 scopus 로고    scopus 로고
    • The contribution of cd4+ cd25+ t-regulatory-cells to immune suppression in sepsis
    • Wisnoski, N., C. S. Chung, Y. Chen, X. Huang, and A. Ayala. 2007. The contribution of CD4+ CD25+ T-regulatory-cells to immune suppression in sepsis. Shock 27: 251-257.
    • (2007) Shock , vol.27 , pp. 251-257
    • Wisnoski, N.1    Chung, C.S.2    Chen, Y.3    Huang, X.4    Ayala, A.5
  • 28
    • 34250890817 scopus 로고    scopus 로고
    • Pathophysiology of sepsis
    • Remick, D. G. 2007. Pathophysiology of sepsis. Am. J. Pathol. 170: 1435-1444.
    • (2007) Am. J. Pathol , vol.170 , pp. 1435-1444
    • Remick, D.G.1
  • 29
    • 84864140315 scopus 로고    scopus 로고
    • The early phase of human sepsis is characterized by a combination of apoptosis and proliferation of t cells
    • Roger, P. M., H. Hyvernat, M. Ticchioni, G. Kumar, J. Dellamonica, and G. Bernardin. 2012. The early phase of human sepsis is characterized by a combination of apoptosis and proliferation of T cells. J. Crit. Care 27: 384-393.
    • (2012) J. Crit. Care , vol.27 , pp. 384-393
    • Roger, P.M.1    Hyvernat, H.2    Ticchioni, M.3    Kumar, G.4    Dellamonica, J.5    Bernardin, G.6
  • 30
    • 33746364004 scopus 로고    scopus 로고
    • How to identify systemic sepsis-induced immunoparalysis
    • Monneret, G. 2005. How to identify systemic sepsis-induced immunoparalysis. Adv. Sepsis 4: 42-49.
    • (2005) Adv. Sepsis , vol.4 , pp. 42-49
    • Monneret, G.1
  • 31
    • 0030004108 scopus 로고    scopus 로고
    • Mechanism of hepatocellular dysfunction during hyperdynamic sepsis
    • Wang, P., and I. H. Chaudry. 1996. Mechanism of hepatocellular dysfunction during hyperdynamic sepsis. Am. J. Physiol. 270: R927-R938.
    • (1996) Am. J. Physiol , vol.270
    • Wang, P.1    Chaudry, I.H.2
  • 33
    • 33751231090 scopus 로고    scopus 로고
    • Pneumonia after cecal ligation and puncture: A clinically relevant "two-hit" model of sepsis
    • Muenzer, J. T., C. G. Davis, B. S. Dunne, J. Unsinger, W. M. Dunne, and R. S. Hotchkiss. 2006. Pneumonia after cecal ligation and puncture: a clinically relevant "two-hit" model of sepsis. Shock 26: 565-570.
    • (2006) Shock , vol.26 , pp. 565-570
    • Muenzer, J.T.1    Davis, C.G.2    Dunne, B.S.3    Unsinger, J.4    Dunne, W.M.5    Hotchkiss, R.S.6
  • 34
    • 34548662180 scopus 로고    scopus 로고
    • Thermal injury-plus-sepsis contributes to a substantial deletion of intestinal mesenteric lymph node cd4 t cell via apoptosis
    • Fazal, N., and W. M. Al-Ghoul. 2007. Thermal injury-plus-sepsis contributes to a substantial deletion of intestinal mesenteric lymph node CD4 T cell via apoptosis. Int. J. Biol. Sci. 3: 393-401.
    • (2007) Int. J. Biol. Sci , vol.3 , pp. 393-401
    • Fazal, N.1    Al-Ghoul, W.M.2
  • 35
    • 84888325490 scopus 로고    scopus 로고
    • Sepsis-induced immunosuppression: From cellular dysfunctions to immunotherapy
    • Hotchkiss, R. S., G. Monneret, and D. Payen. 2013. Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy. Nat. Rev. Immunol. 13: 862-874.
    • (2013) Nat. Rev. Immunol , Issue.13 , pp. 862-874
    • Hotchkiss, R.S.1    Monneret, G.2    Payen, D.3
  • 37
    • 8544236263 scopus 로고    scopus 로고
    • Increased percentage of cd4+cd25+ regulatory t cells during septic shock is due to the decrease of cd4+cd252 lymphocytes
    • Venet, F., A. Pachot, A. L. Debard, J. Bohé, J. Bienvenu, A. Lepape, and G. Monneret. 2004. Increased percentage of CD4+CD25+ regulatory T cells during septic shock is due to the decrease of CD4+CD252 lymphocytes. Crit. Care Med. 32: 2329-2331.
    • (2004) Crit. Care Med , vol.32 , pp. 2329-2331
    • Venet, F.1    Pachot, A.2    Debard, A.L.3    Bohé, J.4    Bienvenu, J.5    Lepape, A.6    Monneret, G.7
  • 38
    • 0031928035 scopus 로고    scopus 로고
    • Sepsis induces increased apoptosis in lamina propria mononuclear cells which is associated with altered cytokine gene expression
    • Chung, C. S., Y. X. Xu, I. H. Chaudry, and A. Ayala. 1998. Sepsis induces increased apoptosis in lamina propria mononuclear cells which is associated with altered cytokine gene expression. J. Surg. Res. 77: 63-70.
    • (1998) J. Surg. Res , vol.77 , pp. 63-70
    • Chung, C.S.1    Xu, Y.X.2    Chaudry, I.H.3    Ayala, A.4
  • 39
    • 0034659411 scopus 로고    scopus 로고
    • Immune suppression in polymicrobial sepsis: Differential regulation of th1 and th2 responses by p38 mapk
    • Song, G. Y., C. S. Chung, I. H. Chaudry, and A. Ayala. 2000. Immune suppression in polymicrobial sepsis: differential regulation of Th1 and Th2 responses by p38 MAPK. J. Surg. Res. 91: 141-146.
    • (2000) J. Surg. Res , vol.91 , pp. 141-146
    • Song, G.Y.1    Chung, C.S.2    Chaudry, I.H.3    Ayala, A.4
  • 40
    • 0033838948 scopus 로고    scopus 로고
    • Immune depression in polymicrobial sepsis: The role of necrotic (injured) tissue and endotoxin
    • Ayala, A., G. Y. Song, C. S. Chung, K. M. Redmond, and I. H. Chaudry. 2000. Immune depression in polymicrobial sepsis: the role of necrotic (injured) tissue and endotoxin. Crit. Care Med. 28: 2949-2955.
    • (2000) Crit. Care Med , vol.28 , pp. 2949-2955
    • Ayala, A.1    Song, G.Y.2    Chung, C.S.3    Redmond, K.M.4    Chaudry, I.H.5
  • 41
    • 33745736420 scopus 로고    scopus 로고
    • T-cell tolerance or function is determined by combinatorial costimulatory signals
    • Nurieva, R., S. Thomas, T. Nguyen, N. Martin-Orozco, Y. Wang, M. K. Kaja, X. Z. Yu, and C. Dong. 2006. T-cell tolerance or function is determined by combinatorial costimulatory signals. EMBO J. 25: 2623-2633.
    • (2006) EMBO J , vol.25 , pp. 2623-2633
    • Nurieva, R.1    Thomas, S.2    Nguyen, T.3    Suciu-Foca, N.4    Wang, Y.5    Kaja, M.K.6    Yu, X.Z.7    Dong, C.8
  • 44
    • 65549083493 scopus 로고    scopus 로고
    • Transcriptional complexes formed by nfat dimers regulate the induction of t cell tolerance
    • Soto-Nieves, N., I. Puga, B. T. Abe, S. Bandyopadhyay, I. Baine, A. Rao, and F. Macian. 2009. Transcriptional complexes formed by NFAT dimers regulate the induction of T cell tolerance. J. Exp. Med. 206: 867-876.
    • (2009) J. Exp. Med , vol.206 , pp. 867-876
    • Soto-Nieves, N.1    Puga, I.2    Abe, B.T.3    Bandyopadhyay, S.4    Baine, I.5    Rao, A.6    Macian, F.7
  • 49
    • 34248151591 scopus 로고    scopus 로고
    • Grail is up-regulated in cd4+ cd25+ t regulatory cells and is sufficient for conversion of t cells to a regulatory phenotype
    • MacKenzie, D. A., J. Schartner, J. Lin, A. Timmel, M. Jennens-Clough, C. G. Fathman, and C. M. Seroogy. 2007. GRAIL is up-regulated in CD4+ CD25+ T regulatory cells and is sufficient for conversion of T cells to a regulatory phenotype. J. Biol. Chem. 282: 9696-9702.
    • (2007) J. Biol. Chem , vol.282 , pp. 9696-9702
    • MacKenzie, D.A.1    Schartner, J.2    Lin, J.3    Timmel, A.4    Huber-Lang, M.5    Fathman, C.G.6    Seroogy, C.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.