GRAIL: A unique mediator of CD4 T-lymphocyte unresponsiveness

FEBS Journal

Volumn 278, Issue 1, 2011, Pages 47-58

  Whiting, Chan C ^a   Su, Leon L ^a   Lin, Jack T ^a   Fathman, C Garrison ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

anergy; cell cycle; de ubiquitinating enzymes (DUBs); E3; GRAIL; RNF128; T cell unresponsiveness; tolerance; ubiquitin protein ligase; ubiquitination

Indexed keywords

CD151 ANTIGEN; CD28 ANTIGEN; CD40 LIGAND; CD81 ANTIGEN; CD83 ANTIGEN; COMPLEMENTARY DNA; EARLY GROWTH RESPONSE FACTOR 2; EARLY GROWTH RESPONSE FACTOR 3; GAMMA INTERFERON; GENE RELATED TO ANERGY IN LYMPHOCYTE; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; ISOPROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; OTUBAIN 1; PROTEIN USP8; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SHORT HAIRPIN RNA; STAPHYLOCOCCUS ENTEROTOXIN B; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR NFAT; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL CYCLE REGULATION; CLONAL ANERGY; CYTOKINE PRODUCTION; ENZYMATIC DEGRADATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HELPER CELL; HUMAN; IMMUNOREGULATION; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; RECEPTOR BLOCKING; REGULATORY T LYMPHOCYTE; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION; UBIQUITINATION;

ANIMALS; AUTOIMMUNE DISEASES; CD4-POSITIVE T-LYMPHOCYTES; CELL CYCLE; HUMANS; MICE; UBIQUITIN-PROTEIN LIGASES;

PYRONIA TITHONUS;

EID: 78650436475     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2010.07922.x     Document Type: Review

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