HCV genomic RNA activates the NLRP3 inflammasome in human myeloid cells

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Chen, Wei ^a   Xu, Yongfen ^a   Li, Hua ^a   Tao, Wanyin ^a   Xiang, Yu ^a   Huang, Bing ^a   Niu, Junqi ^b   Zhong, Jin ^a   Meng, Guangxun ^a  

^a INSTITUTE PASTEUR OF SHANGHAI   (China)

^b THE FIRST HOSPITAL OF JILIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; APOPTOSIS ASSOCIATED SPECKLIKE PROTEIN CONTAINING A CARD; CRYOPYRIN; GENOMIC RNA; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; UNCLASSIFIED DRUG;

ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOKINE RELEASE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; NONHUMAN; OLIGOMERIZATION; PROTEIN CLEAVAGE;

CARRIER PROTEINS; CELL LINE; DEAD-BOX RNA HELICASES; GENOME, VIRAL; HEPACIVIRUS; HEPATITIS C; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; MACROPHAGES; MONOCYTES; MYELOID CELLS; REACTIVE OXYGEN SPECIES; RNA, VIRAL;

EID: 84896456128     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0084953     Document Type: Article

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