NAD+ depletion by APO866 in combination with radiation in a prostate cancer model, results from an in vitro and in vivo study

Radiotherapy and Oncology

Volumn 110, Issue 2, 2014, Pages 348-354

  Zerp, Shuraila F ^a   Vens, Conchita ^a   Floot, Ben ^a   Verheij, Marcel ^a   Van Triest, Baukelien ^a  

^a ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

Author keywords

APO866; Clonogenic survival; Preclinical; Radiation

Indexed keywords

DAPORINAD; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINATE PHOSPHORIBOSYLTRANSFERASE; ACRYLAMIDE DERIVATIVE; N-(4-(1-BENZOYLPIPERIDIN-4-YL)BUTYL)-3-(PYRIDIN-3-YL)ACRYLAMIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PIPERIDINE DERIVATIVE; RADIOSENSITIZING AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER MODEL; CANCER RADIOTHERAPY; CANCER SURVIVAL; CELL STRAIN LNCAP; CELL SURVIVAL; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE TUMOR; PROTEIN DEPLETION; RADIATION RESPONSE; TUMOR GROWTH; TUMOR XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; CELL GROWTH; CHEMORADIOTHERAPY; DEFICIENCY; DRUG EFFECTS; DRUG SCREENING; FEMALE; HUMAN; METABOLISM; PATHOLOGY; PROSTATIC NEOPLASMS; TUMOR CELL LINE;

ACRYLAMIDES; ANIMALS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CELL SURVIVAL; CHEMORADIOTHERAPY; FEMALE; HUMANS; MALE; MICE; MICE, INBRED BALB C; NAD; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PIPERIDINES; PROSTATIC NEOPLASMS; RADIATION-SENSITIZING AGENTS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84896395555     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2013.10.039     Document Type: Article

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