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Volumn 16, Issue 3, 2010, Pages 898-911

Efficacy of combining GMX1777 with radiation therapy for human head and neck carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; FLUORODEOXYGLUCOSE F 18; GLUCOSE; GMX 1777; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; UNCLASSIFIED DRUG;

EID: 76049091888     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-09-1945     Document Type: Article
Times cited : (36)

References (41)
  • 1
    • 53449101276 scopus 로고    scopus 로고
    • Optimizing approaches to head and neck cancer: Strengths and weaknesses in multidisciplinary treatments of locally advanced disease
    • vii195-9
    • Giralt J, Benavente S, Arguis M. Optimizing approaches to head and neck cancer: strengths and weaknesses in multidisciplinary treatments of locally advanced disease. Ann Oncol 2008;19 Suppl 7: vii195-9.
    • (2008) Ann Oncol , vol.19 , Issue.SUPPL. 7
    • Giralt, J.1    Benavente, S.2    Arguis, M.3
  • 2
    • 42149129398 scopus 로고    scopus 로고
    • Head and neck cancer: Changing epidemiology, diagnosis, and treatment
    • Marur S, Forastiere AA. Head and neck cancer: changing epidemiology, diagnosis, and treatment. Mayo Clin Proc 2008;83:489-501.
    • (2008) Mayo Clin Proc , vol.83 , pp. 489-501
    • Marur, S.1    Forastiere, A.A.2
  • 3
    • 43049170497 scopus 로고    scopus 로고
    • A dose escalation study of hyperfractionated accelerated radiation delivered with integrated neck surgery (HARDWINS) for the management of advanced head and neck cancer
    • Waldron J, Warde P, Irish J, et al. A dose escalation study of hyperfractionated accelerated radiation delivered with integrated neck surgery (HARDWINS) for the management of advanced head and neck cancer. Radiother Oncol 2008;87:173-80.
    • (2008) Radiother Oncol , vol.87 , pp. 173-180
    • Waldron, J.1    Warde, P.2    Irish, J.3
  • 4
    • 39749114978 scopus 로고    scopus 로고
    • Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability
    • Bristow RG, Hill RP. Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability. Nat Rev Cancer 2008;8:180-92.
    • (2008) Nat Rev Cancer , vol.8 , pp. 180-192
    • Bristow, R.G.1    Hill, R.P.2
  • 5
    • 44449147036 scopus 로고    scopus 로고
    • Tumor cell metabolism: Cancer's Achilles' heel
    • Kroemer G, Pouyssegur J. Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 2008;13:472-82.
    • (2008) Cancer Cell , vol.13 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 6
    • 33750445309 scopus 로고    scopus 로고
    • NAD metabolism and sirtuins: Metabolic regulation of protein deacetylation in stress and toxicity
    • Yang T, Sauve AA. NAD metabolism and sirtuins: metabolic regulation of protein deacetylation in stress and toxicity. AAPS J 2006;8: E632-43.
    • AAPS , vol.J 2006 , Issue.8
    • Yang, T.1    Sauve, A.A.2
  • 7
    • 62449178216 scopus 로고    scopus 로고
    • The critical role of the class III histone deacetylase SIRT1 in cancer
    • Liu T, Liu PY, Marshall GM. The critical role of the class III histone deacetylase SIRT1 in cancer. Cancer Res 2009;69:1702-5.
    • (2009) Cancer Res , vol.69 , pp. 1702-1705
    • Liu, T.1    Liu, P.Y.2    Marshall, G.M.3
  • 9
    • 0037056219 scopus 로고    scopus 로고
    • Target validation for genomics using peptide-specific phage antibodies: A study of five gene products overexpressed in colorectal cancer
    • Van Beijnum JR, Moerkerk PT, Gerbers AJ, et al. Target validation for genomics using peptide-specific phage antibodies: a study of five gene products overexpressed in colorectal cancer. Int J Cancer 2002;101:118-27.
    • (2002) Int J Cancer , vol.101 , pp. 118-127
    • Van Beijnum, J.R.1    Moerkerk, P.T.2    Gerbers, A.J.3
  • 10
    • 0242526050 scopus 로고    scopus 로고
    • FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis
    • Hasmann M, Schemainda I. FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. Cancer Res 2003;63:7436-42.
    • (2003) Cancer Res , vol.63 , pp. 7436-7442
    • Hasmann, M.1    Schemainda, I.2
  • 11
    • 0033571407 scopus 로고    scopus 로고
    • CHS 828, a novel pyridyl cyanoguanidine with potent antitumor activity in vitro and in vivo
    • Hjarnaa PJ, Jonsson E, Latini S, et al. CHS 828, a novel pyridyl cyanoguanidine with potent antitumor activity in vitro and in vivo. Cancer Res 1999;59:5751-7.
    • (1999) Cancer Res , vol.59 , pp. 5751-5757
    • Hjarnaa, P.J.1    Jonsson, E.2    Latini, S.3
  • 13
    • 70350538957 scopus 로고    scopus 로고
    • + biosynthesis: Strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors
    • + biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors. Mol Cell Biol 2009;29:5872-88.
    • (2009) Mol Cell Biol , vol.29 , pp. 5872-5888
    • Watson, M.1    Roulston, A.2    Belec, L.3
  • 15
    • 67650318141 scopus 로고    scopus 로고
    • Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777
    • Beauparlant P, Bedard D, Bernier C, et al. Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777. Anticancer Drugs 2009;20:346-54.
    • (2009) Anticancer Drugs , vol.20 , pp. 346-354
    • Beauparlant, P.1    Bedard, D.2    Bernier, C.3
  • 16
    • 0032822527 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus
    • Cheung ST, Huang DP, Hui AB, et al. Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus. Int J Cancer 1999;83:121-6.
    • (1999) Int J Cancer , vol.83 , pp. 121-126
    • Cheung, S.T.1    Huang, D.P.2    Hui, A.B.3
  • 17
    • 0036144266 scopus 로고    scopus 로고
    • Tumor-targeted gene therapy for nasopharyngeal carcinoma
    • Li JH, Chia M, Shi W, et al. Tumor-targeted gene therapy for nasopharyngeal carcinoma. Cancer Res 2002;62:171-8.
    • (2002) Cancer Res , vol.62 , pp. 171-178
    • Li, J.H.1    Chia, M.2    Shi, W.3
  • 18
    • 70350462567 scopus 로고    scopus 로고
    • Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer
    • Ito E, Yip KW, Katz D, et al. Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer. Mol Pharmacol 2009;76:969-83.
    • (2009) Mol Pharmacol , vol.76 , pp. 969-983
    • Ito, E.1    Yip, K.W.2    Katz, D.3
  • 19
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔC(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔC(T)) method. Methods 2001;25:402-8.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 20
    • 33749319699 scopus 로고    scopus 로고
    • Benzethonium chloride: A novel anticancer agent identified by using a cell-based small-molecule screen
    • Yip KW, Mao X, Au PY, et al. Benzethonium chloride: a novel anticancer agent identified by using a cell-based small-molecule screen. Clin Cancer Res 2006;12:5557-69.
    • (2006) Clin Cancer Res , vol.12 , pp. 5557-5569
    • Yip, K.W.1    Mao, X.2    Au, P.Y.3
  • 21
    • 58149490629 scopus 로고    scopus 로고
    • Targeting homologous recombination using imatinib results in enhanced tumor cell chemosensitivity and radiosensitivity
    • Choudhury A, Zhao H, Jalali F, et al. Targeting homologous recombination using imatinib results in enhanced tumor cell chemosensitivity and radiosensitivity. Mol Cancer Ther 2009;8:203-13.
    • (2009) Mol Cancer Ther , vol.8 , pp. 203-213
    • Choudhury, A.1    Zhao, H.2    Jalali, F.3
  • 22
    • 66849095262 scopus 로고    scopus 로고
    • 18F]fluorodeoxyglucose positron emission tomography correlates with Akt pathway activity but is not predictive of clinical outcome during mTOR inhibitor therapy
    • 18F]fluorodeoxyglucose positron emission tomography correlates with Akt pathway activity but is not predictive of clinical outcome during mTOR inhibitor therapy. J Clin Oncol 2009;27:2697-704.
    • (2009) J Clin Oncol , vol.27 , pp. 2697-2704
    • Ma, W.W.1    Jacene, H.2    Song, D.3
  • 23
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou TC, Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 1984;22:27-55.
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 24
    • 0345835371 scopus 로고    scopus 로고
    • Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks
    • Banath JP, Olive PL. Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks. Cancer Res 2003;63:4347-50.
    • (2003) Cancer Res , vol.63 , pp. 4347-4350
    • Banath, J.P.1    Olive, P.L.2
  • 25
    • 0034326837 scopus 로고    scopus 로고
    • Celecoxib prevents tumor growth in vivo without toxicity to normal gut: Lack of correlation between in vitro and in vivo models
    • Williams CS, Watson AJ, Sheng H, Helou R, Shao J, DuBois RN. Celecoxib prevents tumor growth in vivo without toxicity to normal gut: lack of correlation between in vitro and in vivo models. Cancer Res 2000;60:6045-51.
    • (2000) Cancer Res , vol.60 , pp. 6045-6051
    • Williams, C.S.1    Watson, A.J.2    Sheng, H.3    Helou, R.4    Shao, J.5    DuBois, R.N.6
  • 26
    • 46749127817 scopus 로고    scopus 로고
    • Tumor cell metabolism imaging
    • Plathow C, Weber WA. Tumor cell metabolism imaging. J Nucl Med 2008;49 Suppl 2:43-63S.
    • (2008) J Nucl Med , vol.49 , Issue.SUPPL. 2
    • Plathow, C.1    Weber, W.A.2
  • 27
    • 0027235843 scopus 로고
    • Factors affecting myocardial 2-[F-18]fluoro-2-deoxy-D-glucose uptake in positron emission tomography studies of normal humans
    • Choi Y, Brunken RC, Hawkins RA, et al. Factors affecting myocardial 2-[F-18]fluoro-2-deoxy-D-glucose uptake in positron emission tomography studies of normal humans. Eur J Nucl Med 1993;20: 308-18.
    • (1993) Eur J Nucl Med , vol.20 , pp. 308-318
    • Choi, Y.1    Brunken, R.C.2    Hawkins, R.A.3
  • 28
    • 51349100760 scopus 로고    scopus 로고
    • 18F-FDG uptake over time
    • author reply 1571
    • 18F-FDG uptake over time. J Nucl Med 2008;49:1570; author reply 1571.
    • (2008) J Nucl Med , vol.49 , pp. 1570
    • Zophel, K.1    Kotzerke, J.2
  • 29
    • 12444346765 scopus 로고    scopus 로고
    • Influence of blood glucose level, age and fasting period on non-pathological FDG uptake in heart and gut
    • de Groot M, Meeuwis AP, Kok PJ, Corstens FH, Oyen WJ. Influence of blood glucose level, age and fasting period on non-pathological FDG uptake in heart and gut. Eur J Nucl Med Mol Imaging 2005;32:98-101.
    • (2005) Eur J Nucl Med Mol Imaging , vol.32 , pp. 98-101
    • de Groot, M.1    Meeuwis, A.P.2    Kok, P.J.3    Corstens, F.H.4    Oyen, W.J.5
  • 30
    • 11444255268 scopus 로고
    • On respiratory impairment in cancer cells
    • Warburg O. On respiratory impairment in cancer cells. Science 1956; 124:269-70.
    • (1956) Science , vol.124 , pp. 269-270
    • Warburg, O.1
  • 31
    • 33846693322 scopus 로고    scopus 로고
    • The regulation of nicotinamide adenine dinucleotide biosynthesis by Nampt/PBEF/visfatin in mammals
    • Revollo JR, Grimm AA, Imai S. The regulation of nicotinamide adenine dinucleotide biosynthesis by Nampt/PBEF/visfatin in mammals. Curr Opin Gastroenterol 2007;23:164-70.
    • (2007) Curr Opin Gastroenterol , vol.23 , pp. 164-170
    • Revollo, J.R.1    Grimm, A.A.2    Imai, S.3
  • 32
    • 0035853385 scopus 로고    scopus 로고
    • Cell death with atypical features induced by the novel antitumoral drug CHS 828, in human U-937 GTB cells
    • Martinsson P, de la Torre M, Binderup L, Nygren P, Larsson R. Cell death with atypical features induced by the novel antitumoral drug CHS 828, in human U-937 GTB cells. Eur J Pharmacol 2001;417:181-7.
    • (2001) Eur J Pharmacol , vol.417 , pp. 181-187
    • Martinsson, P.1    de la Torre, M.2    Binderup, L.3    Nygren, P.4    Larsson, R.5
  • 33
    • 0037091007 scopus 로고    scopus 로고
    • Modulation of pyridyl cyanoguanidine (CHS 828) induced cytotoxicity by 3-aminobenzamide in U-937 GTB cells
    • Lovborg H, Martinsson P, Gullbo J, Ekelund S, Nygren P, Larsson R. Modulation of pyridyl cyanoguanidine (CHS 828) induced cytotoxicity by 3-aminobenzamide in U-937 GTB cells. Biochem Pharmacol 2002; 63:1491-8.
    • (2002) Biochem Pharmacol , vol.63 , pp. 1491-1498
    • Lovborg, H.1    Martinsson, P.2    Gullbo, J.3    Ekelund, S.4    Nygren, P.5    Larsson, R.6
  • 34
    • 14844291424 scopus 로고    scopus 로고
    • Phase I study and pharmacokinetic of CHS-828, a guanidino-containing compound, administered orally as a single dose every 3 weeks in solid tumours: An ECSG/EORTC study
    • Ravaud A, Cerny T, Terret C, et al. Phase I study and pharmacokinetic of CHS-828, a guanidino-containing compound, administered orally as a single dose every 3 weeks in solid tumours: an ECSG/EORTC study. Eur J Cancer 2005;41:702-7.
    • (2005) Eur J Cancer , vol.41 , pp. 702-707
    • Ravaud, A.1    Cerny, T.2    Terret, C.3
  • 35
    • 0036800697 scopus 로고    scopus 로고
    • The combination of the antitumoural pyridyl cyanoguanidine CHS 828 and etoposide in vitro - from cytotoxic synergy to complete inhibition of apoptosis
    • Martinsson P, Ekelund S, Nygren P, Larsson R. The combination of the antitumoural pyridyl cyanoguanidine CHS 828 and etoposide in vitro - from cytotoxic synergy to complete inhibition of apoptosis. Br J Pharmacol 2002;137:568-73.
    • (2002) Br J Pharmacol , vol.137 , pp. 568-573
    • Martinsson, P.1    Ekelund, S.2    Nygren, P.3    Larsson, R.4
  • 37
    • 38149105811 scopus 로고    scopus 로고
    • The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor
    • Holen K, Saltz LB, Hollywood E, Burk K, Hanauske AR. The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor. Invest New Drugs 2008; 26:45-51.
    • (2008) Invest New Drugs , vol.26 , pp. 45-51
    • Holen, K.1    Saltz, L.B.2    Hollywood, E.3    Burk, K.4    Hanauske, A.R.5
  • 40
    • 42349084337 scopus 로고    scopus 로고
    • Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: Novel insights into visfatin-induced angiogenesis
    • Adya R, Tan BK, Punn A, Chen J, Randeva HS. Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: novel insights into visfatin-induced angiogenesis. Cardiovasc Res 2008;78:356-65.
    • (2008) Cardiovasc Res , vol.78 , pp. 356-365
    • Adya, R.1    Tan, B.K.2    Punn, A.3    Chen, J.4    Randeva, H.S.5
  • 41
    • 34147118466 scopus 로고    scopus 로고
    • Visfatin promotes angiogenesis by activation of extracellular signal-regulated kinase 1/2
    • Kim SR, Bae SK, Choi KS, et al. Visfatin promotes angiogenesis by activation of extracellular signal-regulated kinase 1/2. Biochem Biophys Res Commun 2007;357:150-6.
    • (2007) Biochem Biophys Res Commun , vol.357 , pp. 150-156
    • Kim, S.R.1    Bae, S.K.2    Choi, K.S.3


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