Inhibition of endothelial ERK signalling by Smad1/5 is essential for haematopoietic stem cell emergence

Nature Communications

Volumn 5, Issue , 2014, Pages

  Zhang, Chunxia ^a   Lv, Junhua ^a   He, Qiuping ^a   Wang, Sifeng ^a   Gao, Ya ^a   Meng, Anming ^b   Yang, Xiao ^c   Liu, Feng ^a  

^a INSTITUTE OF ZOOLOGY   (China)

^b Peking University   (China)

^c BEIJING INSTITUTE OF BIOTECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 [4 METHYL 2 (2 OXO 3 INDOLINYLMETHYLIDENYL) 3 PYRROLYL]PROPIONIC ACID; HISTONE DEACETYLASE 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SEMAXANIB; SMAD1 PROTEIN; SMAD5 PROTEIN; TRICHOSTATIN A; VALPROIC ACID; PHOTOPROTEIN; ZEBRAFISH PROTEIN;

CELL ORGANELLE; EMBRYONIC DEVELOPMENT; INHIBITION; SIGNAL; VERTEBRATE;

ADULT; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL FATE; CELL TRANSFORMATION; CONTROLLED STUDY; DEACETYLATION; EMBRYO; ENDOTHELIAL TO HAEMATOPOIETIC TRANSITION; ENDOTHELIUM CELL; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GASTRULATION; GENE EXPRESSION; HEMANGIOBLAST; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HISTONE ACETYLATION; MOUSE; NONHUMAN; PROMOTER REGION; SIGNAL TRANSDUCTION; TIGHT JUNCTION; WESTERN BLOTTING; ANIMAL; ANIMAL EMBRYO; CONFOCAL MICROSCOPY; CYTOLOGY; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; IN SITU HYBRIDIZATION; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC ANIMAL; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; VASCULAR ENDOTHELIUM; ZEBRA FISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOTTING, WESTERN; EMBRYO, NONMAMMALIAN; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HISTONE DEACETYLASE 1; IN SITU HYBRIDIZATION; LUMINESCENT PROTEINS; MAP KINASE SIGNALING SYSTEM; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMAD1 PROTEIN; SMAD5 PROTEIN; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84896323263     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4431     Document Type: Article

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