Fev regulates hematopoietic stem cell development via ERK signaling

Blood

Volumn 122, Issue 3, 2013, Pages 367-375

  Wang, Lu ^a   Liu, Tianhui ^b   Xu, Linjie ^c   Gao, Ya ^a   Wei, Yonglong ^a   Duan, Caiwen ^b   Chen, Guo Qiang ^b   Lin, Shuo ^d   Patient, Roger ^e   Zhang, Bo ^c   Hong, Dengli ^b   Liu, Feng ^a  

^a INSTITUTE OF ZOOLOGY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c Peking University   (China)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; TRANSCRIPTION FACTOR ETS; TRANSCRIPTION FACTOR FEV; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 3; DNA BINDING PROTEIN; FEV PROTEIN, HUMAN; FEV PROTEIN, ZEBRAFISH; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR; ZEBRAFISH PROTEIN;

ANIMAL CELL; ARTICLE; CELL MATURATION; CELL POPULATION; CHEMICAL ANALYSIS; CONTROLLED STUDY; EMBRYO; GENETIC ANALYSIS; HEMANGIOBLAST; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMUS; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; AORTA; CELL LINEAGE; CYTOLOGY; ENDOTHELIUM; ENZYMOLOGY; FETUS BLOOD; METABOLISM;

ANIMALS; AORTA; CELL LINEAGE; DNA-BINDING PROTEINS; EMBRYO, NONMAMMALIAN; ENDOTHELIUM; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FETAL BLOOD; HEMATOPOIETIC STEM CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; NUCLEAR PROTEINS; TRANSCRIPTION FACTORS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84884658431     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-10-462655     Document Type: Article

References (39)

1. Bertrand JY, Chi NC, Santoso B, Teng S, Stainier DY, Traver D. Haematopoietic stem cells derive directly from aortic endothelium during development. Nature. 2010;464(7285):108-111.
2. Kissa K, Herbomel P. Blood stem cells emerge from aortic endothelium by a novel type of cell transition. Nature. 2010;464(7285):112-115.
3. Boisset JC, van Cappellen W, Andrieu-Soler C, Galjart N, Dzierzak E, Robin C. In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium. Nature. 2010;464(7285): 116-120.
4. Orkin SH, Zon LI. Hematopoiesis: an evolving paradigm for stem cell biology. Cell. 2008;132(4): 631-644.
5. Ciau-Uitz A, Liu F, Patient R. Genetic control of hematopoietic development in Xenopus and zebrafish. Int J Dev Biol. 2010;54(6-7):1139-1149.
6. Jaffredo T, Gautier R, Eichmann A, Dieterlen-Lièvre F. Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny. Development. 1998;125(22):4575-4583.
7. Gering M, Patient R. Hedgehog signaling is required for adult blood stem cell formation in zebrafish embryos. Dev Cell. 2005;8(3):389-400.
8. Ciau-Uitz A, Walmsley M, Patient R. Distinct origins of adult and embryonic blood in Xenopus. Cell. 2000;102(6):787-796.
9. Zhang C, Patient R, Liu F. Hematopoietic stem cell development and regulatory signaling in zebrafish. Biochim Biophys Acta. 2013;1830(2): 2370-2374.
10. North TE, de Bruijn MF, Stacy T, et al. Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo. Immunity. 2002;16(5):661-672.
11. Dzierzak E, Speck NA. Of lineage and legacy: the development of mammalian hematopoietic stem cells. Nat Immunol. 2008;9(2):129-136.
12. Mucenski ML, McLain K, Kier AB, et al. A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell. 1991; 65(4):677-689.
13. Dejana E, Taddei A, Randi AM. Foxs and Ets in the transcriptional regulation of endothelial cell differentiation and angiogenesis. Biochim Biophys Acta. 2007;1775(2):298-312.
14. De Val S, Chi NC, Meadows SM, et al. Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors. Cell. 2008;135(6):1053-1064.
15. Taoudi S, Bee T, Hilton A, et al. ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification. Genes Dev. 2011; 25(3):251-262.
16. Ciau-Uitz A, Pinheiro P, Gupta R, Enver T, Patient R. Tel1/ETV6 specifies blood stem cells through the agency of VEGF signaling. Dev Cell. 2010; 18(4):569-578.
17. Loughran SJ, Kruse EA, Hacking DF, et al. The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells. Nat Immunol. 2008; 9(7):810-819.
18. Liu F, Patient R. Genome-wide analysis of the zebrafish ETS family identifies three genes required for hemangioblast differentiation or angiogenesis. Circ Res. 2008;103(10):1147-1154.
19. Lillesaar C, Tannhäuser B, Stigloher C, Kremmer E, Bally-Cuif L. The serotonergic phenotype is acquired by converging genetic mechanisms within the zebrafish central nervous system. Dev Dyn. 2007;236(4):1072-1084.
20. Hendricks T, Francis N, Fyodorov D, Deneris ES. The ETS domain factor Pet-1 is an early and precise marker of central serotonin neurons and interacts with a conserved element in serotonergic genes. J Neurosci. 1999;19(23):10348-10356.
21. Hendricks TJ, Fyodorov DV, Wegman LJ, et al. Pet-1 ETS gene plays a critical role in 5-HT neuron development and is required for normal anxiety-like and aggressive behavior. Neuron. 2003;37(2):233-247.
22. Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF. Stages of embryonic development of the zebrafish. Dev Dyn. 1995;203(3):253-310.
23. Wang L, Zhang P, Wei Y, Gao Y, Patient R, Liu F. A blood flow-dependent klf2a-NO signaling cascade is required for stabilization of hematopoietic stem cell programming in zebrafish embryos. Blood. 2011;118(15):4102-4110.
24. Ma D, Wang L, Wang S, Gao Y, Wei Y, Liu F. Foxn1 maintains thymic epithelial cells to support T-cell development via mcm2 in zebrafish. Proc Natl Acad Sci USA. 2012;109(51):21040-21045.
25. Plaster N, Sonntag C, Busse CE, Hammerschmidt M. p53 deficiency rescues apoptosis and differentiation of multiple cell types in zebrafish flathead mutants deficient for zygotic DNA polymerase delta1. Cell Death Differ. 2006; 13(2):223-235.
26. Kratz E, Eimon PM, Mukhyala K, et al. Functional characterization of the Bcl-2 gene family in the zebrafish. Cell Death Differ. 2006;13(10): 1631-1640.
27. Huang P, Xiao A, Zhou M, Zhu Z, Lin S, Zhang B. Heritable gene targeting in zebrafish using customized TALENs. Nat Biotechnol. 2011;29(8): 699-700.
28. Lawson ND, Vogel AM, Weinstein BM. sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation. Dev Cell. 2002;3(1): 127-136.
29. Wilkinson RN, Pouget C, Gering M, Russell AJ, Davies SG, Kimelman D, Patient R. Hedgehog and Bmp polarize hematopoietic stem cell emergence in the zebrafish dorsal aorta. Dev Cell. 2009;16(6):909-916.
30. Krens SF, He S, Lamers GE, et al. Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation. Dev Biol. 2008;319(2):370-383.
31. Kobayashi H, Butler JM, O’Donnell R, et al. Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells. Nat Cell Biol. 2010; 12(11):1046-1056.
32. Hong D, Gupta R, Ancliff P, et al. Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia. Science. 2008; 319(5861):336-339.
33. Gupta R, Hong D, Iborra F, Sarno S, Enver T. NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells. Science. 2007;316(5824):590-593.
34. Doulatov S, Notta F, Laurenti E, Dick JE. Hematopoiesis: a human perspective. Cell Stem Cell. 2012;10(2):120-136.
35. Piacibello W, Sanavio F, Severino A, et al. Engraftment in nonobese diabetic severe combined immunodeficient mice of human CD34 (1) cord blood cells after ex vivo expansion: evidence for the amplification and self-renewal of repopulating stem cells. Blood. 1999;93(11): 3736-3749.
36. Chen MJ, Yokomizo T, Zeigler BM, Dzierzak E, Speck NA. Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter. Nature. 2009;457(7231):887-891.
37. Yue R, Li H, Liu H, et al. Thrombin receptor regulates hematopoiesis and endothelial-to-hematopoietic transition. Dev Cell. 2012;22(5): 1092-1100.
38. Yang M, Li K, Ng PC, et al. Promoting effects of serotonin on hematopoiesis: ex vivo expansion of cord blood CD341 stem/progenitor cells, proliferation of bone marrow stromal cells, and antiapoptosis. Stem Cells. 2007;25(7): 1800-1806.
39. Gerber HP, Malik AK, Solar GP, et al. VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism. Nature. 2002; 417(6892):954-958.