메뉴 건너뛰기




Volumn 2013, Issue , 2013, Pages

Effect of crataegus usage in cardiovascular disease prevention: An evidence-based approach

Author keywords

[No Author keywords available]

Indexed keywords

ANTIARRHYTHMIC AGENT; CARDIOVASCULAR AGENT; CRATAEGUS LAEVIGATA EXTRACT; FLAVONOID; PLANT EXTRACT; TRITERPENE; UNCLASSIFIED DRUG;

EID: 84896123292     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2013/149363     Document Type: Review
Times cited : (109)

References (116)
  • 1
    • 77649259318 scopus 로고    scopus 로고
    • Health effects of hawthorn
    • 2-s2.0-77649259318
    • Dahmer S., Scott E., Health effects of hawthorn. American Family Physician 2010 81 4 465 469 2-s2.0-77649259318
    • (2010) American Family Physician , vol.81 , Issue.4 , pp. 465-469
    • Dahmer, S.1    Scott, E.2
  • 3
  • 5
    • 34447298907 scopus 로고    scopus 로고
    • Traditional knowledge of wild edible plants used in the northwest of the Iberian Peninsula (Spain and Portugal): A comparative study
    • DOI 10.1186/1746-4269-3-27
    • Pardo-De-Santayana M., Tardío J., Blanco E., Carvalho A. M., Lastra J. J., San Miguel E., Morales R., Traditional knowledge of wild edible plants used in the northwest of the Iberian Peninsula (Spain and Portugal): a comparative study. Journal of Ethnobiology and Ethnomedicine 2007 41 5 1 11 2-s2.0-34447298907 10.1186/1746-4269-3-27 (Pubitemid 47053745)
    • (2007) Journal of Ethnobiology and Ethnomedicine , vol.3 , pp. 27
    • Pardo-de-Santayana, M.1    Tardio, J.2    Blanco, E.3    Carvalho, A.M.4    Lastra, J.J.5    San Miguel, E.6    Morales, R.7
  • 6
    • 0001905006 scopus 로고
    • Hawthorn: A literature review
    • Hobbs C., Foster S., Hawthorn: a literature review. Herbaigram 1990 22 4 19 33
    • (1990) Herbaigram , vol.22 , Issue.4 , pp. 19-33
    • Hobbs, C.1    Foster, S.2
  • 8
    • 16344387585 scopus 로고    scopus 로고
    • Hawthorn: Potential roles in cardiovascular disease
    • DOI 10.1142/S0192415X05002606, PII S0192415X05002606
    • Chang W.-T., Dao J., Shao Z.-H., Hawthorn: potential roles in cardiovascular disease. The American Journal of Chinese Medicine 2005 33 1 1 10 2-s2.0-16344387585 10.1142/S0192415X05002606 (Pubitemid 40468298)
    • (2005) American Journal of Chinese Medicine , vol.33 , Issue.1 , pp. 1-10
    • Chang, W.-T.1    Dao, J.2    Shao, Z.-H.3
  • 9
    • 0032247159 scopus 로고    scopus 로고
    • Botanical influences on cardiovascular disease
    • Miller A. L., Botanical influences on cardiovascular disease. Alternative Medicine Review 1998 3 6 422 431 2-s2.0-0032247159 (Pubitemid 128709688)
    • (1998) Alternative Medicine Review , vol.3 , Issue.6 , pp. 422-431
    • Miller, A.L.1
  • 10
    • 79960708470 scopus 로고    scopus 로고
    • Standardized extracts from hawthorn leaves and flowers in the treatment of cardiovascular disorders - Preclinical and clinical studies
    • 2-s2.0-79960708470 10.1055/s-0030-1270849
    • Koch E., Malek F. A., Standardized extracts from hawthorn leaves and flowers in the treatment of cardiovascular disorders-preclinical and clinical studies. Planta Medica 2011 33 1 1 10 2-s2.0-79960708470 10.1055/s-0030-1270849
    • (2011) Planta Medica , vol.33 , Issue.1 , pp. 1-10
    • Koch, E.1    Malek, F.A.2
  • 11
    • 33750528551 scopus 로고    scopus 로고
    • Effect of hawthorn (Crataegus oxycantha) crude extract and chromatographic fractions on multiple activities in a cultured cardiomyocyte assay
    • DOI 10.1016/j.phymed.2006.01.005, PII S094471130600016X
    • Long S. R., Carey R. A., Crofoot K. M., Proteau P. J., Filtz T. M., Effect of hawthorn (Crataegus oxycantha) crude extract and chromatographic fractions on multiple activities in a cultured cardiomyocyte assay. Phytomedicine 2006 13 9-10 643 650 2-s2.0-33750528551 10.1016/j.phymed.2006.01. 005 (Pubitemid 44666402)
    • (2006) Phytomedicine , vol.13 , Issue.9-10 , pp. 643-650
    • Long, S.R.1    Carey, R.A.2    Crofoot, K.M.3    Proteau, P.J.4    Filtz, T.M.5
  • 12
    • 0037938807 scopus 로고    scopus 로고
    • Hawthorn extract for treating chronic heart failure: Meta-analysis of randomized trials
    • DOI 10.1016/S0002-9343(03)00131-1
    • Pittler M. H., Schmidt K., Ernst E., Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials. The American Journal of Medicine 2003 114 8 665 674 2-s2.0-0037938807 10.1016/S0002-9343(03)00131-1 (Pubitemid 36703236)
    • (2003) American Journal of Medicine , vol.114 , Issue.8 , pp. 665-674
    • Pittler, M.H.1    Schmidt, K.2    Ernst, E.3
  • 13
    • 43849093969 scopus 로고    scopus 로고
    • Hawthorn extract for treating chronic heart failure
    • DOI 10.1002/14651858.CD005312.pub2
    • Pittler M. H., Guo R., Ernst E., Hawthorn extract for treating chronic heart failure. Cochrane Database of Systematic Reviews 2008 1 2-s2.0-43849093969 10.1002/14651858.CD005312.pub2 CD005312 (Pubitemid 351807566)
    • (2008) Cochrane Database of Systematic Reviews , Issue.1
    • Pittler, M.H.1    Guo, R.2    Ernst, E.3
  • 15
    • 38049049838 scopus 로고    scopus 로고
    • 4 ‴ -Acetylvitexin-2 ″ - O -rhamnoside, isoorientin, orientin, and 8-methoxykaempferol-3- O -glucoside as markers for the differentiation of Crataegus monogyna and Crataegus pentagyna from Crataegus laevigata (Rosaceae)
    • 2-s2.0-38049049838 10.1002/cbdv.200790241
    • Prinz S., Ring A., Huefner A., Pemp E., Kopp B., 4 ‴ -Acetylvitexin-2 ″-O -rhamnoside, isoorientin, orientin, and 8-methoxykaempferol-3- O -glucoside as markers for the differentiation of Crataegus monogyna and Crataegus pentagyna from Crataegus laevigata (Rosaceae). Chemistry and Biodiversity 2007 4 12 2920 2931 2-s2.0-38049049838 10.1002/cbdv.200790241
    • (2007) Chemistry and Biodiversity , vol.4 , Issue.12 , pp. 2920-2931
    • Prinz, S.1    Ring, A.2    Huefner, A.3    Pemp, E.4    Kopp, B.5
  • 16
    • 84862005288 scopus 로고    scopus 로고
    • A review of the chemistry of the genus Crataegus
    • Jennifer E. E., Paula N. B., A review of the chemistry of the genus Crataegus. Phytochemistry 2012 79 1 5 26
    • (2012) Phytochemistry , vol.79 , Issue.1 , pp. 5-26
    • Jennifer, E.E.1    Paula, N.B.2
  • 17
    • 56349110985 scopus 로고    scopus 로고
    • Towards a systematic scientific approach in the assessment of efficacy of an herbal preparation: Hawthorn (Crataegus spp.)
    • 2-s2.0-56349110985 10.1016/j.ejheart.2008.10.003
    • Furey A., Tassell M., Towards a systematic scientific approach in the assessment of efficacy of an herbal preparation: hawthorn (Crataegus spp.). European Journal of Heart Failure 2008 10 12 1153 1157 2-s2.0-56349110985 10.1016/j.ejheart.2008.10.003
    • (2008) European Journal of Heart Failure , vol.10 , Issue.12 , pp. 1153-1157
    • Furey, A.1    Tassell, M.2
  • 18
    • 61749094923 scopus 로고    scopus 로고
    • Crataegus orientalis associated multiorgan hypersensitivity reaction and acute renal failure
    • 2-s2.0-61749094923 10.2169/internalmedicine.47.1502
    • Horoz M., Gok E., Genctoy G., Ozcan T., Olmaz R., Akca M., Kiykim A., Gurses I., Crataegus orientalis associated multiorgan hypersensitivity reaction and acute renal failure. Internal Medicine 2008 47 1 2039 2042 2-s2.0-61749094923 10.2169/internalmedicine.47.1502
    • (2008) Internal Medicine , vol.47 , Issue.1 , pp. 2039-2042
    • Horoz, M.1    Gok, E.2    Genctoy, G.3    Ozcan, T.4    Olmaz, R.5    Akca, M.6    Kiykim, A.7    Gurses, I.8
  • 20
    • 84896110528 scopus 로고    scopus 로고
    • 7th Strasbourg, France Council of Europe
    • European Pharmacopoeia 7.0 2007 1 7th Strasbourg, France Council of Europe
    • (2007) European Pharmacopoeia 7.0 , vol.1
  • 21
    • 25844526463 scopus 로고    scopus 로고
    • Isolation and identification of flavonoids, including flavone rotamers, from the herbal drug 'Crateagi folium cum flore' (hawthorn)
    • DOI 10.1002/pca.853
    • Rayyan S., Fossen T., Solheim Nateland H., Andersen Ø. M., Isolation and identification of flavonoids, including flavone rotamers, from the herbal drug (hawthorn). Phytochemical Analysis 2005 16 5 334 341 2-s2.0-25844526463 10.1002/pca.853 (Pubitemid 41388237)
    • (2005) Phytochemical Analysis , vol.16 , Issue.5 , pp. 334-341
    • Rayyan, S.1    Fossen, T.2    Solheim Nateland, H.3    Andersen, O.M.4
  • 23
    • 0036173267 scopus 로고    scopus 로고
    • Quantification of procyanidins in oral herbal medicinal products containing extracts of Crataegus species
    • Wittig J., Leipolz I., Graefe E. U., Jaki B., Treutter D., Veit M., Quantification of procyanidins in oral herbal medicinal products containing extracts of Crataegus species. Arzneimittel-Forschung 2002 52 2 89 96 2-s2.0-0036173267 (Pubitemid 34145326)
    • (2002) Arzneimittel-Forschung/Drug Research , vol.52 , Issue.2 , pp. 89-96
    • Wittig, J.1    Leipolz, I.2    Graefe, E.U.3    Jaki, B.4    Treutter, D.5    Veit, M.6
  • 25
    • 84896134282 scopus 로고    scopus 로고
    • Hawthorn leaf and flower
    • Scientific Cooperative On Phytotherapy Exeter, UK
    • European Scientific Cooperative on Phytotherapy, Hawthorn leaf and flower. ESCOP Monographs on the Medicinal Uses of Plant Drugs 1999 Exeter, UK 1 11
    • (1999) ESCOP Monographs on the Medicinal Uses of Plant Drugs , pp. 1-11
  • 26
    • 12744274729 scopus 로고    scopus 로고
    • Folium cum flore crataegi
    • Geneva, Switzerland World Health Organization
    • Folium cum flore crataegi. WHO Monographs on Selected Medicinal Plants 2002 Geneva, Switzerland World Health Organization 66 82
    • (2002) WHO Monographs on Selected Medicinal Plants , pp. 66-82
  • 27
    • 0033964818 scopus 로고    scopus 로고
    • Apoptosis induction by nitric oxide in adult cardiomyocytes via cGMP- signaling and its impairment after simulated ischemia
    • DOI 10.1016/S0008-6363(99)00272-2, PII S0008636399002722
    • Taimor G., Hofstaetter B., Piper H. M., Apoptosis induction by nitric oxide in adult cardiomyocytes via cGMP- signaling and its impairment after simulated ischemia. Cardiovascular Research 2000 45 3 588 594 2-s2.0-0033964818 10.1016/S0008-6363(99)00272-2 (Pubitemid 30047125)
    • (2000) Cardiovascular Research , vol.45 , Issue.3 , pp. 588-594
    • Taimor, G.1    Hofstaetter, B.2    Piper, H.M.3
  • 28
    • 3042857531 scopus 로고    scopus 로고
    • Cardioprotective effect of tincture of Crataegus on isoproterenol-induced myocardial infarction in rats
    • DOI 10.1211/0022357023745
    • Jayalakshmi R., Devaraj S. N., Cardioprotective effect of tincture of Crataegus on isoproterenol-induced myocardial infarction in rats. Journal of Pharmacy and Pharmacology 2004 56 7 921 926 2-s2.0-3042857531 10.1211/0022357023745 (Pubitemid 38885987)
    • (2004) Journal of Pharmacy and Pharmacology , vol.56 , Issue.7 , pp. 921-926
    • Jayalakshmi, R.1    Devaraj, S.N.2
  • 29
    • 33750733952 scopus 로고    scopus 로고
    • Pretreatment with alcoholic extract of shape Crataegus oxycantha (AEC) activates mitochondrial protection during isoproterenol - Induced myocardial infarction in rats
    • DOI 10.1007/s11010-006-9218-3
    • Jayalakshmi R., Thirupurasundari C. J., Devaraj S. N., Pretreatment with alcoholic extract of shape Crataegus oxycantha (AEC) activates mitochondrial protection during isoproterenol-induced myocardial infarction in rats. Molecular and Cellular Biochemistry 2006 292 1-2 59 67 2-s2.0-33750733952 10.1007/s11010-006-9218-3 (Pubitemid 44697400)
    • (2006) Molecular and Cellular Biochemistry , vol.292 , Issue.1-2 , pp. 59-67
    • Jayalakshmi, R.1    Thirupurasundari, C.J.2    Devaraj, S.N.3
  • 30
    • 73449101482 scopus 로고    scopus 로고
    • The effect of Crataegus fruit extract and some of its flavonoids on mitochondrial oxidative phosphorylation in the heart
    • 2-s2.0-73449101482 10.1002/ptr.2815
    • Bernatoniene J., Trumbeckaite S., Majiene D., Baniene R., Baliutyte G., Savickas A., Toleikis A., The effect of Crataegus fruit extract and some of its flavonoids on mitochondrial oxidative phosphorylation in the heart. Phytotherapy Research 2009 23 12 1701 1707 2-s2.0-73449101482 10.1002/ptr.2815
    • (2009) Phytotherapy Research , vol.23 , Issue.12 , pp. 1701-1707
    • Bernatoniene, J.1    Trumbeckaite, S.2    Majiene, D.3    Baniene, R.4    Baliutyte, G.5    Savickas, A.6    Toleikis, A.7
  • 31
    • 0034018535 scopus 로고    scopus 로고
    • Crataegus special extract WS 1442 increases force of contraction in human myocardium cAMP-independently
    • DOI 10.1097/00005344-200005000-00004
    • Schwinger R. H. G., Pietsch M., Frank K., Brixius K., Crataegus special extract WS 1442 increases force of contraction in human myocardium cAMP-independently. Journal of Cardiovascular Pharmacology 2000 35 5 700 707 2-s2.0-0034018535 10.1097/00005344-200005000-00004 (Pubitemid 30253609)
    • (2000) Journal of Cardiovascular Pharmacology , vol.35 , Issue.5 , pp. 700-707
    • Schwinger, R.H.G.1    Pietsch, M.2    Frank, K.3    Brixius, K.4
  • 32
    • 57349117287 scopus 로고    scopus 로고
    • A comparison of the effects of commercially available hawthorn preparations on calcium transients of isolated cardiomyocytes
    • 2-s2.0-57349117287 10.1089/jmf.2008.0080
    • Rodriguez M. E., Poindexter B. J., Bick R. J., Dasgupta A., A comparison of the effects of commercially available hawthorn preparations on calcium transients of isolated cardiomyocytes. Journal of Medicinal Food 2008 11 4 680 686 2-s2.0-57349117287 10.1089/jmf.2008.0080
    • (2008) Journal of Medicinal Food , vol.11 , Issue.4 , pp. 680-686
    • Rodriguez, M.E.1    Poindexter, B.J.2    Bick, R.J.3    Dasgupta, A.4
  • 33
    • 33947376446 scopus 로고    scopus 로고
    • Activation of immune and inflammatory systems in chronic heart failure: Novel therapeutic approaches
    • DOI 10.1111/j.1742-1241.2007.01295.x
    • Gong K. Z., Song G., Spiers J. P., Kelso E. J., Zhang Z. G., Activation of immune and inflammatory systems in chronic heart failure: novel therapeutic approaches. International Journal of Clinical Practice 2007 61 4 611 621 2-s2.0-33947376446 10.1111/j.1742-1241.2007.01295.x (Pubitemid 46449822)
    • (2007) International Journal of Clinical Practice , vol.61 , Issue.4 , pp. 611-621
    • Gong, K.Z.1    Song, G.2    Spiers, J.P.3    Kelso, E.J.4    Zhang, Z.G.5
  • 35
    • 0038544209 scopus 로고    scopus 로고
    • Mast cells and oral inflammation
    • Walsh L. J., Mast cells and oral inflammation. Critical Reviews in Oral Biology and Medicine 2003 14 3 188 198 2-s2.0-0038544209 10.1177/ 154411130301400304 (Pubitemid 44560803)
    • (2003) Critical Reviews in Oral Biology and Medicine , vol.14 , Issue.3 , pp. 188-198
    • Walsh, L.J.1
  • 36
    • 79956263596 scopus 로고    scopus 로고
    • Anti-inflammatory effect of the water fraction from hawthorn fruit on LPS-stimulated RAW 264.7 cells
    • 2-s2.0-79956263596 10.4162/nrp.2011.5.2.101
    • Li C., Wang M.-H., Anti-inflammatory effect of the water fraction from hawthorn fruit on LPS-stimulated RAW 264.7 cells. Nutrition Research and Practice 2011 5 2 101 106 2-s2.0-79956263596 10.4162/nrp.2011.5.2.101
    • (2011) Nutrition Research and Practice , vol.5 , Issue.2 , pp. 101-106
    • Li, C.1    Wang, M.-H.2
  • 37
    • 84856778748 scopus 로고    scopus 로고
    • Anti-inflammatory and anti-apoptotic effects of Crataegus oxyacantha on isoproterenol-induced myocardial damage
    • 2-s2.0-84856778748 10.1007/s11010-012-1251-9
    • Vijayan N. A., Thiruchenduran M., Devaraj S. N., Anti-inflammatory and anti-apoptotic effects of Crataegus oxyacantha on isoproterenol-induced myocardial damage. Molecular and Cellular Biochemistry 2012 367 1-2 1 8 2-s2.0-84856778748 10.1007/s11010-012-1251-9
    • (2012) Molecular and Cellular Biochemistry , vol.367 , Issue.1-2 , pp. 1-8
    • Vijayan, N.A.1    Thiruchenduran, M.2    Devaraj, S.N.3
  • 38
    • 47049102727 scopus 로고    scopus 로고
    • Hawthorn extract inhibits human isolated neutrophil functions
    • 2-s2.0-47049102727 10.1016/j.phrs.2008.05.001
    • Dalli E., Milara J., Cortijo J., Morcillo E. J., Cosín-Sales J., Sotillo J. F., Hawthorn extract inhibits human isolated neutrophil functions. Pharmacological Research 2008 57 6 445 450 2-s2.0-47049102727 10.1016/j.phrs.2008.05.001
    • (2008) Pharmacological Research , vol.57 , Issue.6 , pp. 445-450
    • Dalli, E.1    Milara, J.2    Cortijo, J.3    Morcillo, E.J.4    Cosín-Sales, J.5    Sotillo, J.F.6
  • 39
    • 0030975710 scopus 로고    scopus 로고
    • 2 inhibition
    • Ahumada C., Sáenz T., García D., De La Puerta R., Fernandez A., Martinez E., The effects of a triterpene fraction isolated from Crataegus monogyna Jacq. on different acute inflammation models in rats and mice. leucocyte migration and phospholipase A2 inhibition. Journal of Pharmacy and Pharmacology 1997 49 3 329 331 2-s2.0-0030975710 10.1111/j.2042-7158.1997. tb06806.x (Pubitemid 27197024)
    • (1997) Journal of Pharmacy and Pharmacology , vol.49 , Issue.3 , pp. 329-331
    • Ahumada, C.1    Saenz, T.2    Garcia, D.3    De La Puerta, R.4    Fernandez, A.5    Martinez, E.6
  • 40
    • 0002537440 scopus 로고    scopus 로고
    • Cardiac hypertrophy: the good, the bad, and the ugly
    • DOI 10.1146/annurev.physiol.65.092101.142243
    • Frey N., Olson E. N., Cardiac hypertrophy: the good, the bad, and the ugly. Annual Review of Physiology 2003 367 1-2 45 79 2-s2.0-0002537440 10.1146/annurev.physiol.65.092101.142243 (Pubitemid 38249147)
    • (2003) Annual Review of Physiology , vol.65 , pp. 45-79
    • Frey, N.1    Olson, E.N.2
  • 41
    • 39149100639 scopus 로고    scopus 로고
    • Effects of hawthorn on cardiac remodeling and left ventricular dysfunction after 1 month of pressure overload-induced cardiac hypertrophy in rats
    • 2-s2.0-39149100639 10.1007/s10557-008-6082-2
    • Hwang H. S., Bleske B. E., Ghannam M. M. J., Converso K., Russell M. W., Hunter J. C., Boluyt M. O., Effects of hawthorn on cardiac remodeling and left ventricular dysfunction after 1 month of pressure overload-induced cardiac hypertrophy in rats. Cardiovascular Drugs and Therapy 2008 22 1 19 28 2-s2.0-39149100639 10.1007/s10557-008-6082-2
    • (2008) Cardiovascular Drugs and Therapy , vol.22 , Issue.1 , pp. 19-28
    • Hwang, H.S.1    Bleske, B.E.2    Ghannam, M.M.J.3    Converso, K.4    Russell, M.W.5    Hunter, J.C.6    Boluyt, M.O.7
  • 42
    • 0036107689 scopus 로고    scopus 로고
    • Dietary components and human platelet activity
    • DOI 10.1080/09537100120111540
    • Dutta-Roy A. K., Dietary components and human platelet activity. Platelets 2002 13 2 67 75 2-s2.0-0036107689 10.1080/09537100120111540 (Pubitemid 34407247)
    • (2002) Platelets , vol.13 , Issue.2 , pp. 67-75
    • Dutta-Roy, A.K.1
  • 43
    • 12244259062 scopus 로고    scopus 로고
    • Antiplatelet prescribing patterns for TIA and ischemic stroke: The Indiana University experience
    • DOI 10.1016/S0022-510X(02)00348-9, PII S0022510X02003489
    • Mayer T. O., Biller J., Antiplatelet prescribing patterns for TIA and ischemic stroke: the Indiana University experience. Journal of the Neurological Sciences 2003 207 1-2 5 10 2-s2.0-12244259062 10.1016/S0022-510X(02)00348-9 (Pubitemid 36287096)
    • (2003) Journal of the Neurological Sciences , vol.207 , Issue.1-2 , pp. 5-10
    • Mayer, T.O.1    Biller, J.2
  • 44
    • 0036930050 scopus 로고    scopus 로고
    • Appropriate antiplatelet and antithrombotic therapy in patients with acute coronary syndromes: Recent updates to the ACC/AHA guidelines
    • 2-s2.0-0036930050
    • Mehta S. R., Appropriate antiplatelet and antithrombotic therapy in patients with acute coronary syndromes: recent updates to the ACC/AHA guidelines. Journal of Invasive Cardiology 2002 14 1-2 27 34 2-s2.0-0036930050
    • (2002) Journal of Invasive Cardiology , vol.14 , Issue.1-2 , pp. 27-34
    • Mehta, S.R.1
  • 45
    • 84861810164 scopus 로고    scopus 로고
    • Effect of hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino Wistar rats
    • 10.1016/j.thromres.2012.01.001
    • Abdullah S. S., Hesham S., Fahaid A. H., Effect of hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino Wistar rats. Thrombosis Research 2012 130 1 75 80 10.1016/j.thromres.2012.01.001
    • (2012) Thrombosis Research , vol.130 , Issue.1 , pp. 75-80
    • Abdullah, S.S.1    Hesham, S.2    Fahaid, A.H.3
  • 46
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • DOI 10.1038/288373a0
    • Furchgott R. F., Zawadzki J. V., The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980 288 5789 373 376 2-s2.0-0019195506 10.1038/288373a0 (Pubitemid 11169009)
    • (1980) Nature , vol.288 , Issue.5789 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 47
    • 0023912670 scopus 로고
    • Vascular endothelial cells synthesize nitric oxide from L-arginine
    • 2-s2.0-0023912670 10.1038/333664a0
    • Palmer R. M. J., Ashton D. S., Moncada S., Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988 333 6174 664 666 2-s2.0-0023912670 10.1038/333664a0
    • (1988) Nature , vol.333 , Issue.6174 , pp. 664-666
    • Palmer, R.M.J.1    Ashton, D.S.2    Moncada, S.3
  • 49
    • 0033055559 scopus 로고    scopus 로고
    • Endothelial dysfunction: From physiology to therapy
    • DOI 10.1006/jmcc.1998.0844
    • Mombouli J.-V., Vanhoutte P. M., Endothelial dysfunction: from physiology to therapy. Journal of Molecular and Cellular Cardiology 1999 31 1 61 74 2-s2.0-0033055559 10.1006/jmcc.1998.0844 (Pubitemid 29078219)
    • (1999) Journal of Molecular and Cellular Cardiology , vol.31 , Issue.1 , pp. 61-74
    • Mombouli, J.-V.1    Vanhoutte, P.M.2
  • 50
    • 33746257055 scopus 로고    scopus 로고
    • Crataegus special extract WS® 1442 induces an endothelium-dependent, NO-mediated vasorelaxation via eNOS-phosphorylation at serine 1177
    • DOI 10.1007/s10557-006-8723-7
    • Brixius K., Willms S., Napp A., Tossios P., Ladage D., Bloch W., Mehlhorn U., Schwinger R. H. G., Crataegus special extract WS 1442 induces an endothelium-dependent, NO-mediated vasorelaxation via eNOS-phosphorylation at serine 1177. Cardiovascular Drugs and Therapy 2006 20 3 177 184 2-s2.0-33746257055 10.1007/s10557-006-8723-7 (Pubitemid 44099815)
    • (2006) Cardiovascular Drugs and Therapy , vol.20 , Issue.3 , pp. 177-184
    • Brixius, K.1    Willms, S.2    Napp, A.3    Tossios, P.4    Ladage, D.5    Bloch, W.6    Mehlhorn, U.7    Schwinger, R.H.G.8
  • 51
    • 67649231705 scopus 로고    scopus 로고
    • Crataegus special extract WS 1442 causes endothelium-dependent relaxation via a redox-sensitive Src- and Akt-dependent activation of endothelial NO synthase but not via activation of estrogen receptors
    • 2-s2.0-67649231705 10.1097/FJC.0b013e31819ccfc9
    • Anselm E., Socorro V. F. M., Dal-Ros S., Schott C., Bronner C., Schini-Kerth V. B., Crataegus special extract WS 1442 causes endothelium-dependent relaxation via a redox-sensitive Src- and Akt-dependent activation of endothelial NO synthase but not via activation of estrogen receptors. Journal of Cardiovascular Pharmacology 2009 59 3 253 260 2-s2.0-67649231705 10.1097/FJC.0b013e31819ccfc9
    • (2009) Journal of Cardiovascular Pharmacology , vol.59 , Issue.3 , pp. 253-260
    • Anselm, E.1    Socorro, V.F.M.2    Dal-Ros, S.3    Schott, C.4    Bronner, C.5    Schini-Kerth, V.B.6
  • 52
    • 84874935280 scopus 로고    scopus 로고
    • Effects of Crataegus microphylla on vascular dysfunction in streptozotocin-induced diabetic rats
    • 10.1002/ptr.4726
    • Gökçe T., Koç E., Karaca Ç., Tuncay A., Effects of Crataegus microphylla on vascular dysfunction in streptozotocin-induced diabetic rats. Phytotherapy Research 2013 27 3 330 337 10.1002/ptr.4726
    • (2013) Phytotherapy Research , vol.27 , Issue.3 , pp. 330-337
    • Gökçe, T.1    Koç, E.2    Karaca, Ç.3    Tuncay, A.4
  • 54
    • 0034595790 scopus 로고    scopus 로고
    • Procyanidins in crataegus extract evoke endothelium-dependent vasorelaxation in rat aorta
    • DOI 10.1016/S0024-3205(00)00608-1, PII S0024320500006081
    • Kim S. H., Kang K. W., Kim K. W., Kim N. D., Procyanidins in Crataegus extract evoke endothelium-dependent vasorelaxation in rat aorta. Life Sciences 2000 67 2 121 131 2-s2.0-0034595790 10.1016/S0024-3205(00)00608-1 (Pubitemid 30414479)
    • (2000) Life Sciences , vol.67 , Issue.2 , pp. 121-131
    • Kim, S.H.1    Kang, K.W.2    Kim, K.W.3    Kim, N.D.4
  • 55
    • 82755160802 scopus 로고    scopus 로고
    • Hawthorn special extract WS 1442 increases red blood cell NO-formation without altering red blood cell deformability
    • 2-s2.0-82755160802 10.1016/j.phymed.2011.08.059
    • Rieckeheer E., Schwinger R. H. G., Bloch W., Brixius K., Hawthorn special extract WS 1442 increases red blood cell NO-formation without altering red blood cell deformability. Phytomedicine 2011 19 1 20 24 2-s2.0-82755160802 10.1016/j.phymed.2011.08.059
    • (2011) Phytomedicine , vol.19 , Issue.1 , pp. 20-24
    • Rieckeheer, E.1    Schwinger, R.H.G.2    Bloch, W.3    Brixius, K.4
  • 56
    • 0032501120 scopus 로고    scopus 로고
    • Herbal medicinals: Selected clinical considerations focusing on known or potential drug-herb interactions
    • DOI 10.1001/archinte.158.20.2200
    • Miller L. G., Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions. Archives of Internal Medicine 1998 158 20 2200 2211 2-s2.0-0032501120 10.1001/archinte.158.20.2200 (Pubitemid 28512494)
    • (1998) Archives of Internal Medicine , vol.158 , Issue.20 , pp. 2200-2211
    • Miller, L.G.1
  • 57
    • 0036620538 scopus 로고    scopus 로고
    • Endothelial dysfunction in the pathogenesis of atherosclerosis
    • Poredos P., Endothelial dysfunction in the pathogenesis of atherosclerosis. International Angiology 2002 21 2 109 116
    • (2002) International Angiology , vol.21 , Issue.2 , pp. 109-116
    • Poredos, P.1
  • 58
    • 0034120111 scopus 로고    scopus 로고
    • The bronchial microcirculation in asthma
    • Wilson J., The bronchial microcirculation in asthma. Clinical and Experimental Allergy 2000 30 1 51 53 2-s2.0-0034120111 10.1046/j.1365-2222.2000. 00098.x (Pubitemid 30341379)
    • (2000) Clinical and Experimental Allergy, Supplement , vol.30 , Issue.1 , pp. 51-53
    • Wilson, J.1
  • 59
    • 0034123126 scopus 로고    scopus 로고
    • Endothelium function in sepsis
    • DOI 10.1007/s000110050579
    • Volk T., Kox W. J., Endothelium function in sepsis. Inflammation Research 2000 49 5 185 198 2-s2.0-0034123126 10.1007/s000110050579 (Pubitemid 30353684)
    • (2000) Inflammation Research , vol.49 , Issue.5 , pp. 185-198
    • Volk, T.1    Kox, W.J.2
  • 60
    • 0036852427 scopus 로고    scopus 로고
    • Peripheral edema
    • DOI 10.1016/S0002-9343(02)01322-0, PII S0002934302013220
    • Cho S., Atwood J. E., Peripheral edema. The American Journal of Medicine 2002 113 7 580 586 2-s2.0-0036852427 10.1016/S0002-9343(02)01322-0 (Pubitemid 35379914)
    • (2002) American Journal of Medicine , vol.113 , Issue.7 , pp. 580-586
    • Cho, S.1    Atwood, J.E.2
  • 63
    • 84861818314 scopus 로고    scopus 로고
    • Crataegus special extract WS 1442 prevents aging-related endothelial dysfunction
    • 10.1016/j.phymed.2012.04.005
    • Idris-Khodja N., Auger C., Koch E., Schini-Kerth V.B., Crataegus special extract WS 1442 prevents aging-related endothelial dysfunction. Phytomedicine 2012 19 8-9 699 706 10.1016/j.phymed.2012.04.005
    • (2012) Phytomedicine , vol.19 , Issue.8-9 , pp. 699-706
    • Idris-Khodja, N.1    Auger, C.2    Koch, E.3    Schini-Kerth, V.B.4
  • 64
    • 0028323629 scopus 로고
    • Percutaneous transluminal coronary angioplasty
    • DOI 10.1056/NEJM199404073301407
    • Landau C., Lange R. A., Hillis L. D., Percutaneous transluminal coronary angioplasty. The New England Journal of Medicine 1994 330 14 981 993 2-s2.0-0028323629 10.1056/NEJM199404073301407 (Pubitemid 24103598)
    • (1994) New England Journal of Medicine , vol.330 , Issue.14 , pp. 981-993
    • Landau, C.1    Lange, R.A.2    Hillis, L.D.3
  • 65
    • 77955246548 scopus 로고    scopus 로고
    • The Crataegus extract WS 1442 inhibits balloon catheter-induced intimal hyperplasia in the rat carotid artery by directly influencing PDGFR- β
    • 2-s2.0-77955246548 10.1016/j.atherosclerosis.2010.04.003
    • Fürst R., Zirrgiebel U., Totzke F., Zahler S., Vollmar A. M., Koch E., The Crataegus extract WS 1442 inhibits balloon catheter-induced intimal hyperplasia in the rat carotid artery by directly influencing PDGFR- β Atherosclerosis 2010 211 2 409 417 2-s2.0-77955246548 10.1016/j.atherosclerosis. 2010.04.003
    • (2010) Atherosclerosis , vol.211 , Issue.2 , pp. 409-417
    • Fürst, R.1    Zirrgiebel, U.2    Totzke, F.3    Zahler, S.4    Vollmar, A.M.5    Koch, E.6
  • 66
    • 38349123913 scopus 로고    scopus 로고
    • Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion
    • 2-s2.0-38349123913 10.1016/j.pharmthera.2007.09.008
    • Han J.-Y., Fan J.-Y., Horie Y., Miura S., Cui D.-H., Ishii H., Hibi T., Tsuneki H., Kimura I., Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion. Pharmacology and Therapeutics 2008 117 2 280 295 2-s2.0-38349123913 10.1016/j.pharmthera.2007.09.008
    • (2008) Pharmacology and Therapeutics , vol.117 , Issue.2 , pp. 280-295
    • Han, J.-Y.1    Fan, J.-Y.2    Horie, Y.3    Miura, S.4    Cui, D.-H.5    Ishii, H.6    Hibi, T.7    Tsuneki, H.8    Kimura, I.9
  • 67
    • 0842324493 scopus 로고    scopus 로고
    • Crataegus special extract WS® 1442 improves cardiac function and reduces infarct size in a rat model of prolonged coronary ischemia and reperfusion
    • DOI 10.1016/j.lfs.2003.09.050
    • Veveris M., Koch E., Chatterjee S. S., Crataegus special extract WS 1442 improves cardiac function and reduces infarct size in a rat model of prolonged coronary ischemia and reperfusion. Life Sciences 2004 74 15 1945 1955 2-s2.0-0842324493 10.1016/j.lfs.2003.09.050 (Pubitemid 38167562)
    • (2004) Life Sciences , vol.74 , Issue.15 , pp. 1945-1955
    • Veveris, M.1    Koch, E.2    Chatterjee, S.S.3
  • 68
    • 0032964592 scopus 로고    scopus 로고
    • Protective effect of Crataegus oxyacantha against reperfusion arrhythmias after global no-flow ischemia in the rat heart
    • DOI 10.1007/s003950050128
    • Al Makdessi S., Sweidan H., Dietz K., Jacob R., Protective effect of Crataegus oxyacantha against reperfusion arrhythmias after global no-flow ischemia in the rat heart. Basic Research in Cardiology 1999 94 2 71 77 2-s2.0-0032964592 10.1007/s003950050128 (Pubitemid 29182380)
    • (1999) Basic Research in Cardiology , vol.94 , Issue.2 , pp. 71-77
    • Al Makdessi, S.1    Sweidan, H.2    Dietz, K.3    Jacob, R.4
  • 69
    • 3042857531 scopus 로고    scopus 로고
    • Cardioprotective effect of tincture of Crataegus on isoproterenol-induced myocardial infarction in rats
    • DOI 10.1211/0022357023745
    • Jayalakshmi R., Devaraj S. N., Cardioprotective effect of tincture of Crataegus on isoproterenol-induced myocardial infarction in rats. Journal of Pharmacy and Pharmacology 2004 56 7 921 926 2-s2.0-3042857531 10.1211/0022357023745 (Pubitemid 38885987)
    • (2004) Journal of Pharmacy and Pharmacology , vol.56 , Issue.7 , pp. 921-926
    • Jayalakshmi, R.1    Devaraj, S.N.2
  • 70
    • 3142630286 scopus 로고    scopus 로고
    • Crataegus extract prolongs action potential duration in guinea-pig papillary muscle
    • Müller A., Linke W., Zhao Y., Klaus W., Crataegus extract prolongs action potential duration in guinea-pig papillary muscle. Phytomedicine 1996 3 3 257 261 2-s2.0-3142630286 (Pubitemid 126504567)
    • (1996) Phytomedicine , vol.3 , Issue.3 , pp. 257-261
    • Muller, A.1    Linke, W.2    Zhao, Y.3    Klaus, W.4
  • 71
    • 0032967328 scopus 로고    scopus 로고
    • Crataegus extract blocks potassium currents in guinea pig ventricular cardiac myocytes
    • DOI 10.1055/s-1999-13997
    • Müller A., Linke W., Klaus W., Crataegus extract blocks potassium currents in guinea pig ventricular cardiac myocytes. Planta Medica 1999 65 4 335 339 2-s2.0-0032967328 10.1055/s-1999-13997 (Pubitemid 29249907)
    • (1999) Planta Medica , vol.65 , Issue.4 , pp. 335-339
    • Muller, A.1    Linke, W.2    Klaus, W.3
  • 72
    • 0033812937 scopus 로고    scopus 로고
    • Effects of extracts from flowering tops of crataegus meyeri a. Pojark. On ischaemic arrhythmias in anaesthetized rats
    • Garjani A., Nazemiyeh H., Maleki N., Valizadeh H., Effects of extracts from flowering tops of Crataegus meyeri A. Pojark. on ischaemic arrhythmias in anaesthetized rats. Phytotherapy Research 2000 14 6 428 431
    • (2000) Phytotherapy Research , vol.14 , Issue.6 , pp. 428-431
    • Garjani, A.1    Nazemiyeh, H.2    Maleki, N.3    Valizadeh, H.4
  • 73
    • 16344387585 scopus 로고    scopus 로고
    • Hawthorn: Potential roles in cardiovascular disease
    • DOI 10.1142/S0192415X05002606, PII S0192415X05002606
    • Chang W.-T., Dao J., Shao Z.-H., Hawthorn: potential roles in cardiovascular disease. The American Journal of Chinese Medicine 2005 33 1 1 10 2-s2.0-16344387585 10.1142/S0192415X05002606 (Pubitemid 40468298)
    • (2005) American Journal of Chinese Medicine , vol.33 , Issue.1 , pp. 1-10
    • Chang, W.-T.1    Dao, J.2    Shao, Z.-H.3
  • 74
    • 0035219503 scopus 로고    scopus 로고
    • Herbs and atherosclerosis
    • 2-s2.0-0035219503 10.1007/s11883-001-0016-9
    • Heber D., Herbs and atherosclerosis. Current Atherosclerosis Reports 2001 3 1 93 96 2-s2.0-0035219503 10.1007/s11883-001-0016-9
    • (2001) Current Atherosclerosis Reports , vol.3 , Issue.1 , pp. 93-96
    • Heber, D.1
  • 76
    • 74049153853 scopus 로고    scopus 로고
    • A study of the comparative effects of hawthorn fruit compound and simvastatin on lowering blood lipid levels
    • 2-s2.0-74049153853 10.1142/S0192415X09007302
    • Xu H., Xu H.-E., Ryan D., A study of the comparative effects of hawthorn fruit compound and simvastatin on lowering blood lipid levels. The American Journal of Chinese Medicine 2009 37 5 903 908 2-s2.0-74049153853 10.1142/S0192415X09007302
    • (2009) The American Journal of Chinese Medicine , vol.37 , Issue.5 , pp. 903-908
    • Xu, H.1    Xu, H.-E.2    Ryan, D.3
  • 77
    • 0029949399 scopus 로고    scopus 로고
    • Effect of tincture of Crataegus on the LDL-receptor activity of hepatic plasma membrane of rats fed an atherogenic diet
    • DOI 10.1016/0021-9150(96)05813-3
    • Rajendran S., Deepalakshmi P. D., Parasakthy K., Devaraj H., Devaraj S. N., Effect of tincture of Crataegus on the LDL-receptor activity of hepatic plasma membrane of rats fed an atherogenic diet. Atherosclerosis 1996 123 1-2 235 241 2-s2.0-0029949399 10.1016/0021-9150(96)05813-3 (Pubitemid 26175078)
    • (1996) Atherosclerosis , vol.123 , Issue.1-2 , pp. 235-241
    • Rajendran, S.1    Deepalakshmi, P.D.2    Parasakthy, K.3    Devaraj, H.4    Devaraj, S.N.5
  • 78
    • 0036140196 scopus 로고    scopus 로고
    • Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet
    • Zhang Z., Ho W. K. K., Huang Y., Anthony E. J., Lam L. W., Chen Z.-Y., Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet. Journal of Nutrition 2002 132 1 5 10 2-s2.0-0036140196 (Pubitemid 34042447)
    • (2002) Journal of Nutrition , vol.132 , Issue.1 , pp. 5-10
    • Zhang, Z.1    Ho, W.K.K.2    Huang, Yu.3    Anthony, E.J.4    Lam, L.W.5    Chen, Z.-Y.6
  • 79
    • 79955686550 scopus 로고    scopus 로고
    • Regulation effects of Crataegus pinnatifida leaf on glucose and lipids metabolism
    • 2-s2.0-79955686550 10.1021/jf1049062
    • Wang T., An Y., Zhao C., Han L., Boakye-Yiadom M., Wang W., Zhang Y., Regulation effects of Crataegus pinnatifida leaf on glucose and lipids metabolism. Journal of Agricultural and Food Chemistry 2011 59 9 4987 4994 2-s2.0-79955686550 10.1021/jf1049062
    • (2011) Journal of Agricultural and Food Chemistry , vol.59 , Issue.9 , pp. 4987-4994
    • Wang, T.1    An, Y.2    Zhao, C.3    Han, L.4    Boakye-Yiadom, M.5    Wang, W.6    Zhang, Y.7
  • 80
    • 31544459510 scopus 로고    scopus 로고
    • Regulation of lipoprotein lipase expression by effect of hawthorn flavonoids on peroxisome proliferator response element pathway
    • DOI 10.1254/jphs.FP0050748
    • Fan C., Yan J., Qian Y., Wo X., Gao L., Regulation of lipoprotein lipase expression by effect of hawthorn flavonoids on peroxisome proliferator response element pathway. Journal of Pharmacological Sciences 2006 100 1 51 58 2-s2.0-31544459510 10.1254/jphs.FP0050748 (Pubitemid 43161614)
    • (2006) Journal of Pharmacological Sciences , vol.100 , Issue.1 , pp. 51-58
    • Fan, C.1    Yan, J.2    Qian, Y.3    Wo, X.4    Gao, L.5
  • 81
    • 55149111397 scopus 로고    scopus 로고
    • Synergistic effect of tincture of Crataegus and Mangifera indica L. Extract on hyperlipidemic and antioxidant status in atherogenic rats
    • 2-s2.0-55149111397 10.1016/j.vph.2008.07.007
    • Akila M., Devaraj H., Synergistic effect of tincture of Crataegus and Mangifera indica L. extract on hyperlipidemic and antioxidant status in atherogenic rats. Vascular Pharmacology 2008 49 4-6 173 177 2-s2.0-55149111397 10.1016/j.vph.2008.07.007
    • (2008) Vascular Pharmacology , vol.49 , Issue.4-6 , pp. 173-177
    • Akila, M.1    Devaraj, H.2
  • 82
    • 84867728195 scopus 로고    scopus 로고
    • Whole plant based treatment of hypercholesterolemia with Crataegus laevigata in a zebrafish model
    • article 105 10.1186/1472-6882-12-105
    • Robert M. L., Matthew M., Jay R. H., Whole plant based treatment of hypercholesterolemia with Crataegus laevigata in a zebrafish model. Complementary and Alternative Medicine 2012 12 article 105 10.1186/1472-6882-12- 105
    • (2012) Complementary and Alternative Medicine , vol.12
    • Robert, M.L.1    Matthew, M.2    Jay, R.H.3
  • 83
    • 31644441996 scopus 로고    scopus 로고
    • Crataegus tanacetifolia leaf extract prevents L-NAME-induced hypertension in rats: A morphological study
    • DOI 10.1002/ptr.1808
    • Koçyõldõz Z. Ç., Birman H., Olgaç V., Akgün-Dar K., Melikoǧlu G., Meriçli A. H., Crataegus tanacetifolia leaf extract prevents L-NAME-induced hypertension in rats: a morphological study. Phytotherapy Research 2006 20 1 66 70 2-s2.0-31644441996 10.1002/ptr.1808 (Pubitemid 43171591)
    • (2006) Phytotherapy Research , vol.20 , Issue.1 , pp. 66-70
    • Kocyildiz, Z.C.1    Birman, H.2    Olgac, V.3    Akgun-Dar, K.4    Melikoglu, G.5    Mericli, A.H.6
  • 84
    • 84874438036 scopus 로고    scopus 로고
    • In vivo hemodynamic and electrocardiographic changes following Crataegus aronia syn. Azarolus L administration to normotensive Wistar rats
    • Shatoor A. S., In vivo hemodynamic and electrocardiographic changes following Crataegus aronia syn. Azarolus L administration to normotensive Wistar rats. Saudi Medical Journal 2013 34 2 123 134
    • (2013) Saudi Medical Journal , vol.34 , Issue.2 , pp. 123-134
    • Shatoor, A.S.1
  • 86
    • 44649161840 scopus 로고    scopus 로고
    • The effect of Crataegus oxycantha special extract WS 1442 on clinical progression in patients with mild to moderate symptoms of heart failure
    • 2-s2.0-44649161840 10.1016/j.ejheart.2008.04.008
    • Zick S. M., Gillespie B., Aaronson K. D., The effect of Crataegus oxycantha special extract WS 1442 on clinical progression in patients with mild to moderate symptoms of heart failure. European Journal of Heart Failure 2008 10 6 587 593 2-s2.0-44649161840 10.1016/j.ejheart.2008.04.008
    • (2008) European Journal of Heart Failure , vol.10 , Issue.6 , pp. 587-593
    • Zick, S.M.1    Gillespie, B.2    Aaronson, K.D.3
  • 87
    • 0036267583 scopus 로고    scopus 로고
    • Efficacy and safety of crataegus extract WS 1442 in comparison with placebo in patients with chronic stable New York Heart Association class-III heart failure
    • DOI 10.1067/mhj.2002.121463
    • Tauchert M., Efficacy and safety of Crataegus extract WS 1442 in comparison with placebo in patients with chronic stable New York Heart Association class-III heart failure. American Heart Journal 2002 143 5 910 915 2-s2.0-0036267583 10.1067/mhj.2002.121463 (Pubitemid 34595353)
    • (2002) American Heart Journal , vol.143 , Issue.5 , pp. 910-915
    • Tauchert, M.1
  • 88
    • 0037938807 scopus 로고    scopus 로고
    • Hawthorn extract for treating chronic heart failure: Meta-analysis of randomized trials
    • DOI 10.1016/S0002-9343(03)00131-1
    • Pittler M. H., Schmidt K., Ernst E., Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials. The American Journal of Medicine 2003 114 8 665 674 2-s2.0-0037938807 10.1016/S0002-9343(03)00131-1 (Pubitemid 36703236)
    • (2003) American Journal of Medicine , vol.114 , Issue.8 , pp. 665-674
    • Pittler, M.H.1    Schmidt, K.2    Ernst, E.3
  • 89
    • 80255129697 scopus 로고    scopus 로고
    • Baseline severity but not gender modulates quantified Crataegus extract effects in early heart failure - A pooled analysis of clinical trials
    • 2-s2.0-80255129697 10.1016/j.phymed.2011.06.022
    • Eggeling T., Regitz-Zagrosek V., Zimmermann A., Burkart M., Baseline severity but not gender modulates quantified Crataegus extract effects in early heart failure-a pooled analysis of clinical trials. Phytomedicine 2011 18 14 1214 1219 2-s2.0-80255129697 10.1016/j.phymed.2011.06.022
    • (2011) Phytomedicine , vol.18 , Issue.14 , pp. 1214-1219
    • Eggeling, T.1    Regitz-Zagrosek, V.2    Zimmermann, A.3    Burkart, M.4
  • 90
    • 0041940215 scopus 로고    scopus 로고
    • Efficacy of a homeopathic Crataegus preparation compared with usual therapy for mild (NYHA II) cardiac insufficiency: Results of an observational cohort study
    • DOI 10.1016/S1388-9842(02)00237-4
    • Schröder D., Weiser M., Klein P., Efficacy of a homeopathic Crataegus preparation compared with usual therapy for mild (NYHA II) cardiac insufficiency: results of an observational cohort study. European Journal of Heart Failure 2003 5 3 319 326 2-s2.0-0041940215 10.1016/S1388-9842(02)00237-4 (Pubitemid 37011861)
    • (2003) European Journal of Heart Failure , vol.5 , Issue.3 , pp. 319-326
    • Schroder, D.1    Weiser, M.2    Klein, P.3
  • 91
    • 0037532649 scopus 로고    scopus 로고
    • A randomised double blind placebo controlled clinical trial of a standardised extract of fresh Crataegus berries (Crataegisan®) in the treatment of patients with congestive heart failure NYHA II
    • DOI 10.1078/0944-7113-00312
    • Degenring F. H., Suter A., Weber M., Saller R., A randomised double blind placebo controlled clinical trial of a standardised extract of fresh Crataegus berries (Crataegisan) in the treatment of patients with congestive heart failure NYHA II. Phytomedicine 2003 10 5 363 369 2-s2.0-0037532649 10.1078/0944-7113- 00312 (Pubitemid 36745157)
    • (2003) Phytomedicine , vol.10 , Issue.5 , pp. 363-369
    • Degenring, F.H.1    Suter, A.2    Weber, M.3    Saller, R.4
  • 92
    • 0034882022 scopus 로고    scopus 로고
    • Clinical efficacy of crataegus extract WS® 1442 in congestive heart failure NYHA class II
    • Zapfe Jun G., Clinical efficacy of Crataegus extract WS 1442 in congestive heart failure NYHA class II. Phytomedicine 2001 8 4 262 266 2-s2.0-0034882022 10.1078/0944-7113-00041 (Pubitemid 32758341)
    • (2001) Phytomedicine , vol.8 , Issue.4 , pp. 262-266
    • Zapfe Jun, G.1
  • 93
    • 0002197492 scopus 로고
    • Efficacy of the hawthorn (Crataegus) preparation LI 132 in 78 patients with chronic congestive heart failure defined as NYHA functional class II
    • 10.1016/S0944-7113(11)80018-8
    • Schmidt U., Kuhn U., Ploch M., Hübner W. D., Efficacy of the hawthorn (Crataegus) preparation LI 132 in 78 patients with chronic congestive heart failure defined as NYHA functional class II. Phytomedicine 1994 1 1 17 24 10.1016/S0944-7113(11)80018-8
    • (1994) Phytomedicine , vol.1 , Issue.1 , pp. 17-24
    • Schmidt, U.1    Kuhn, U.2    Ploch, M.3    Hübner, W.D.4
  • 94
    • 70349659932 scopus 로고    scopus 로고
    • Hawthorn extract randomized blinded chronic heart failure (HERB CHF) trial
    • 2-s2.0-70349659932 10.1093/eurjhf/hfp116
    • Zick S. M., Vautaw B. M., Gillespie B., Aaronson K. D., Hawthorn extract randomized blinded chronic heart failure (HERB CHF) trial. European Journal of Heart Failure 2009 11 10 990 999 2-s2.0-70349659932 10.1093/eurjhf/hfp116
    • (2009) European Journal of Heart Failure , vol.11 , Issue.10 , pp. 990-999
    • Zick, S.M.1    Vautaw, B.M.2    Gillespie, B.3    Aaronson, K.D.4
  • 95
    • 56349134577 scopus 로고    scopus 로고
    • The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure: The SPICE trial
    • 2-s2.0-56349134577 10.1016/j.ejheart.2008.10.004
    • Holubarsch C. J. F., Colucci W. S., Meinertz T., Gaus W., Tendera M., The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure: the SPICE trial. European Journal of Heart Failure 2008 10 12 1255 1263 2-s2.0-56349134577 10.1016/j.ejheart.2008.10.004
    • (2008) European Journal of Heart Failure , vol.10 , Issue.12 , pp. 1255-1263
    • Holubarsch, C.J.F.1    Colucci, W.S.2    Meinertz, T.3    Gaus, W.4    Tendera, M.5
  • 96
    • 0347423198 scopus 로고    scopus 로고
    • Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
    • DOI 10.1161/01.HYP.0000107251.49515.c2
    • Chobanian A. V., Bakris G. L., Black H. R., Cushman W. C., Green L. A., Izzo J. L. Jr., Jones D. W., Materson B. J., Oparil S., Wright J. T. Jr., Roccella E. J., Seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Hypertension 2003 42 6 1206 1252 2-s2.0-0347423198 10.1161/01.HYP.0000107251.49515.c2 (Pubitemid 37553153)
    • (2003) Hypertension , vol.42 , Issue.6 , pp. 1206-1252
    • Chobanian, A.V.1    Bakris, G.L.2    Black, H.R.3    Cushman, W.C.4    Green, L.A.5    Izzo Jr., J.L.6    Jones, D.W.7    Materson, B.J.8    Oparil, S.9    Wright Jr., J.T.10    Roccella, E.J.11
  • 97
    • 79955136917 scopus 로고    scopus 로고
    • The seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure
    • Institutes of Health Heart Lung And Blood Institute Bethesda, Md, USA NIH publication
    • National Institutes of Health: National Heart, Lung, and Blood Institute, The seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Blood Pressure Education Program, 2003 03-5233 Bethesda, Md, USA NIH publication
    • (2003) Blood Pressure Education Program , Issue.3-5233
  • 98
    • 12344282783 scopus 로고    scopus 로고
    • Global burden of hypertension: Analysis of worldwide data
    • DOI 10.1016/S0140-6736(05)17741-1, PII S0140673605177411
    • Kearney P. M., Whelton M., Reynolds K., Muntner P., Whelton P. K., He J., Global burden of hypertension: analysis of worldwide data. The Lancet 2005 365 9455 217 223 2-s2.0-12344282783 10.1016/S0140-6736(05)17741-1 (Pubitemid 40138015)
    • (2005) Lancet , vol.365 , Issue.9455 , pp. 217-223
    • Kearney, P.M.1    Whelton, M.2    Reynolds, K.3    Muntner, P.4    Whelton, P.K.5    He, J.6
  • 99
    • 79952558248 scopus 로고    scopus 로고
    • Integrating traditional medicine with biomedicine towards a patient-centered healthcare system
    • 2-s2.0-79952558248 10.1007/s11655-011-0641-2
    • Xu H., Chen K.-J., Integrating traditional medicine with biomedicine towards a patient-centered healthcare system. Chinese Journal of Integrative Medicine 2011 17 2 83 84 2-s2.0-79952558248 10.1007/s11655-011-0641-2
    • (2011) Chinese Journal of Integrative Medicine , vol.17 , Issue.2 , pp. 83-84
    • Xu, H.1    Chen, K.-J.2
  • 100
    • 84861081399 scopus 로고    scopus 로고
    • Current situation and perspectives of clinical study in integrative medicine in China
    • 268542 10.1155/2012/268542
    • Wang J., Xiong X. J., Current situation and perspectives of clinical study in integrative medicine in China. Evidence-Based Complementary and Alternative Medicine 2012 2012 11 268542 10.1155/2012/268542
    • (2012) Evidence-Based Complementary and Alternative Medicine , vol.2012 , pp. 11
    • Wang, J.1    Xiong, X.J.2
  • 101
    • 26944475172 scopus 로고    scopus 로고
    • Complementary/alternative medicine for hypertension: A mini-review
    • DOI 10.1007/s10354-005-0205-1
    • Ernst E., Complementary/alternative medicine for hypertension: a mini-review. Wiener Medizinische Wochenschrift 2005 123 17-18 386 391 2-s2.0-26944475172 10.1007/s10354-005-0205-1 (Pubitemid 41482719)
    • (2005) Wiener Medizinische Wochenschrift , vol.155 , Issue.17-18 , pp. 386-391
    • Ernst, E.1
  • 102
    • 84872798783 scopus 로고    scopus 로고
    • Outcome measures of Chinese herbal medicine for hypertension: An overview of systematic reviews
    • 697237 10.1155/2012/697237
    • Wang J., Xiong X. J., Outcome measures of Chinese herbal medicine for hypertension: an overview of systematic reviews. Evidence-Based Complementary and Alternative Medicine 2012 2012 7 697237 10.1155/2012/697237
    • (2012) Evidence-Based Complementary and Alternative Medicine , vol.2012 , pp. 7
    • Wang, J.1    Xiong, X.J.2
  • 103
    • 84871431027 scopus 로고    scopus 로고
    • Chinese patent medicine Liu Wei di Huang Wan combined with antihypertensive drugs, a new integrative medicine therapy, for the treatment of essential hypertension: A systematic review of randomized controlled trials
    • 714805 10.1155/2012/714805
    • Wang J., Xiong X. J., Chinese patent medicine Liu Wei Di Huang Wan combined with antihypertensive drugs, a new integrative medicine therapy, for the treatment of essential hypertension: a systematic review of randomized controlled trials. Evidence-Based Complementary and Alternative Medicine 2012 2012 7 714805 10.1155/2012/714805
    • (2012) Evidence-Based Complementary and Alternative Medicine , vol.2012 , pp. 7
    • Wang, J.1    Xiong, X.J.2
  • 104
    • 84872155143 scopus 로고    scopus 로고
    • Banxia baizhu tianma decoction for essential hypertension: A systematic review of randomized controlled trials
    • 271462 10.1155/2012/271462
    • Wang J., Xiong X. J., Banxia baizhu tianma decoction for essential hypertension: a systematic review of randomized controlled trials. Evidence-Based Complementary and Alternative Medicine 2012 2012 10 271462 10.1155/2012/271462
    • (2012) Evidence-Based Complementary and Alternative Medicine , vol.2012 , pp. 10
    • Wang, J.1    Xiong, X.J.2
  • 105
    • 0036813135 scopus 로고    scopus 로고
    • Camphor-crataegus berry extract combination dose-dependently reduces tilt induced fall in blood pressure in orthostatic hypotension
    • Belz G. G., Butzer R., Gaus W., Loew D., Camphor-Crataegus berry extract combination dose-dependently reduces tilt induced fall in blood pressure in orthostatic hypotension. Phytomedicine 2002 9 7 581 588 2-s2.0-0036813135 10.1078/094471102321616382 (Pubitemid 35397788)
    • (2002) Phytomedicine , vol.9 , Issue.7 , pp. 581-588
    • Belz, G.G.1    Butzer, R.2    Gaus, W.3    Loew, D.4
  • 106
    • 33745156121 scopus 로고    scopus 로고
    • Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: A randomised controlled trial
    • Walker A. F., Marakis G., Simpson E., Hope J. L., Robinson P. A., Hassanein M., Simpson H. C. R., Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial. The British Journal of General Practice 2006 56 527 437 443 2-s2.0-33745156121 (Pubitemid 43891226)
    • (2006) British Journal of General Practice , vol.56 , Issue.527 , pp. 437-443
    • Walker, A.F.1    Marakis, G.2    Simpson, E.3    Hope, J.L.4    Robinson, P.A.5    Hassanein, M.6    Simpson, H.C.R.7
  • 107
    • 0036163304 scopus 로고    scopus 로고
    • Promising hypotensive effect of hawthorn extract: A randomized double-blind pilot study of mild, essential hypertension
    • DOI 10.1002/ptr.947
    • Walker A. F., Marakis G., Morris A. P., Robinson P. A., Promising hypotensive effect of hawthorn extract: a randomized double-blind pilot study of mild, essential hypertension. Phytotherapy Research 2002 16 1 48 54 2-s2.0-0036163304 10.1002/ptr.947 (Pubitemid 34116695)
    • (2002) Phytotherapy Research , vol.16 , Issue.1 , pp. 48-54
    • Walker, A.F.1    Marakis, G.2    Morris, A.P.3    Robinson, P.A.4
  • 108
    • 84858995083 scopus 로고    scopus 로고
    • Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: A randomized, controlled cross-over trial
    • 2-s2.0-84858995083 10.1186/1472-6882-12-26
    • Asher G. N., Viera A. J., Weaver M. A., Dominik R., Caughey M., Hinderliter A. L., Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial. BMC Complementary and Alternative Medicine 2012 12, article 26 2-s2.0-84858995083 10.1186/1472-6882-12-26
    • (2012) BMC Complementary and Alternative Medicine , vol.1226
    • Asher, G.N.1    Viera, A.J.2    Weaver, M.A.3    Dominik, R.4    Caughey, M.5    Hinderliter, A.L.6
  • 109
    • 79958092564 scopus 로고    scopus 로고
    • Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: A randomized, double-blind, placebo-controlled trial
    • 2-s2.0-79958092564 10.1016/j.phymed.2010.11.011
    • Dalli E., Colomer E., Tormos M. C., Cosín-Sales J., Milara J., Esteban E., Sáez G., Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: a randomized, double-blind, placebo-controlled trial. Phytomedicine 2011 18 8-9 769 775 2-s2.0-79958092564 10.1016/j.phymed. 2010.11.011
    • (2011) Phytomedicine , vol.18 , Issue.8-9 , pp. 769-775
    • Dalli, E.1    Colomer, E.2    Tormos, M.C.3    Cosín-Sales, J.4    Milara, J.5    Esteban, E.6    Sáez, G.7
  • 110
    • 79952021256 scopus 로고    scopus 로고
    • Clinical effect of Shanzha Jing Jiangzhi Pill in the treatment of hyperlipidemia
    • Liang Y. F., Ye H., Clinical effect of Shanzha Jing Jiangzhi Pill in the treatment of hyperlipidemia. Strait Pharmaceutical Journal 2004 16 2 93 94
    • (2004) Strait Pharmaceutical Journal , vol.16 , Issue.2 , pp. 93-94
    • Liang, Y.F.1    Ye, H.2
  • 111
    • 84896106997 scopus 로고    scopus 로고
    • Clinical value of the Shanzha Jing Jiangzhi Pill on lipoprotein (a) and the changes of nitric oxide of senile hyperlipidemia patients after intervention
    • Shen Q. L., Lan L. M., Li P. Y., Zhang C. Q., Clinical value of the Shanzha Jing Jiangzhi Pill on lipoprotein (a) and the changes of nitric oxide of senile hyperlipidemia patients after intervention. Strait Pharmaceutical Journal 2000 12 3 85 86
    • (2000) Strait Pharmaceutical Journal , vol.12 , Issue.3 , pp. 85-86
    • Shen, Q.L.1    Lan, L.M.2    Li, P.Y.3    Zhang, C.Q.4
  • 112
    • 13444253027 scopus 로고    scopus 로고
    • Comparative effects of Aegle marmelos extract and alpha-tocopherol on serum lipids, lipid peroxides and cardiac enzyme levels in rats with isoproterenol-induced myocardial infarction
    • Rajadurai M., Prince P. S. M., Comparative effects of Aegle marmelos extract and alpha-tocopherol on serum lipids, lipid peroxides and cardiac enzyme levels in rats with isoproterenol-induced myocardial infarction. Singapore Medical Journal 2005 46 2 78 81 2-s2.0-13444253027 (Pubitemid 40203742)
    • (2005) Singapore Medical Journal , vol.46 , Issue.2 , pp. 78-81
    • Rajadurai, M.1    Prince, P.S.M.2
  • 113
    • 16644375017 scopus 로고    scopus 로고
    • Comparison of the pharmacokinetics of hawthorn phenolics in extract versus individual pure compound
    • 2-s2.0-16644375017 10.1177/0091270004270500
    • Chang Q., Zuo Z., Ho W. K. K., Chow M. S. S., Comparison of the pharmacokinetics of hawthorn phenolics in extract versus individual pure compound. The Journal of Clinical Pharmacology 2005 45 1 106 112 2-s2.0-16644375017 10.1177/0091270004270500
    • (2005) The Journal of Clinical Pharmacology , vol.45 , Issue.1 , pp. 106-112
    • Chang, Q.1    Zuo, Z.2    Ho, W.K.K.3    Chow, M.S.S.4
  • 114
    • 34247109045 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the last 25 years
    • DOI 10.1021/np068054v
    • Newman D. J., Cragg G. M., Natural products as sources of new drugs over the last 25 years. Journal of Natural Products 2007 70 3 461 477 2-s2.0-34247109045 10.1021/np068054v (Pubitemid 46595760)
    • (2007) Journal of Natural Products , vol.70 , Issue.3 , pp. 461-477
    • Newman, D.J.1    Cragg, G.M.2
  • 115
    • 0035238881 scopus 로고    scopus 로고
    • Plants as source of drugs
    • 2-s2.0-0035238881 10.1016/S0041-0101(00)00154-9
    • Rates S. M. K., Plants as source of drugs. Toxicon 2001 39 5 603 613 2-s2.0-0035238881 10.1016/S0041-0101(00)00154-9
    • (2001) Toxicon , vol.39 , Issue.5 , pp. 603-613
    • Rates, S.M.K.1
  • 116
    • 77954650596 scopus 로고    scopus 로고
    • Prospects for growth in global nutraceutical and functional food markets: A Canadian perspective
    • Basu S. K., Thomas J. E., Acharya S. N., Prospects for growth in global nutraceutical and functional food markets: a Canadian perspective. Australian Journal of Basic and Applied Sciences 2007 27 4 637 649
    • (2007) Australian Journal of Basic and Applied Sciences , vol.27 , Issue.4 , pp. 637-649
    • Basu, S.K.1    Thomas, J.E.2    Acharya, S.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.