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Volumn 18, Issue 8-9, 2011, Pages 769-775

Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: A randomized, double-blind, placebo-controlled trial

Author keywords

Coronary heart disease; Crataegus laevigata (Rosaceae); Elastase; Neutrophil function; Randomized, double blind placebo controlled trial

Indexed keywords

ANTILIPEMIC AGENT; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CALCIUM CHANNEL BLOCKING AGENT; CRATAEGUS EXTRACT; CRATAEGUS LAEVIGATA EXTRACT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LEUKOCYTE ELASTASE; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; PLACEBO; PLANT EXTRACT; UNCLASSIFIED DRUG;

EID: 79958092564     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2010.11.011     Document Type: Article
Times cited : (41)

References (54)
  • 3
    • 0030035015 scopus 로고    scopus 로고
    • Myocardial protection by pre-treatment with Crataegus oxyacantha. An assessment by means of the release of lactate dehydrogenase by the ischemic and reperfused Langendorff heart
    • Al Makdessi, S., Sweidan, H., Müllner, S., Jacob, R., 1996. Myocardial protection by pre-treatment with Crataegus oxyacantha. An assessment by means of the release of lactate dehydrogenase by the ischemic and reperfused Langendorff heart. Arzneimittelforsch. Drug Res. 46, 25-27.
    • (1996) Arzneimittelforsch. Drug Res. , vol.46 , pp. 25-27
    • Al Makdessi, S.1    Sweidan, H.2    Müllner, S.3    Jacob, R.4
  • 4
    • 0032964592 scopus 로고    scopus 로고
    • Protective effect of Crataegus oxyacantha against reperfusion arrhythmias after global no-flow ischemia in the rat heart
    • Al Makdessi, Sweidan, H., Dietz, K., Jacob, R., 1999. Protective effect of Crataegus oxyacantha against reperfusion arrhythmias after global no-flow ischemia in the rat heart. Basic Res. Cardiol. 94, 71-77.
    • (1999) Basic Res. Cardiol. , vol.94 , pp. 71-77
    • Makdessi, A.1    Sweidan, H.2    Dietz, K.3    Jacob, R.4
  • 6
    • 11444267569 scopus 로고    scopus 로고
    • Antihypertensive effect of Iranian Crataegus curvisepala Lind.: A randomised double-blind study
    • Asgary, S., Naderi, G.H., Sadeghi, M., Kelishadi, R., Amiri, M., 2004. Antihypertensive effect of Iranian Crataegus curvisepala Lind.: a randomised double-blind study. Drugs Exp. Clin. Res. 30, 221-225.
    • (2004) Drugs Exp. Clin. Res. , vol.30 , pp. 221-225
    • Asgary, S.1    Naderi, G.H.2    Sadeghi, M.3    Kelishadi, R.4    Amiri, M.5
  • 7
    • 0014876627 scopus 로고
    • Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions
    • Burstein, M., Scholnik, H.R., Morfin, R., 1970. Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions. J. Lipid Res. 11, 583-595.
    • (1970) J. Lipid Res. , vol.11 , pp. 583-595
    • Burstein, M.1    Scholnik, H.R.2    Morfin, R.3
  • 10
    • 0030759309 scopus 로고    scopus 로고
    • In vitro and in vivo studies on the cardioprotective action of oligomeric procyanidins in a Crataegus extract of leaves and blooms
    • Chatterjee, S.S., Koch, E., Jaggy, H., Krzeminsky, T., 1997. In vitro and in vivo studies on the cardioprotective action of oligomeric procyanidins in a Crataegus extract of leaves and blooms. Arzneimittelforschung 47, 821-825.
    • (1997) Arzneimittelforschung , vol.47 , pp. 821-825
    • Chatterjee, S.S.1    Koch, E.2    Jaggy, H.3    Krzeminsky, T.4
  • 11
    • 0029192908 scopus 로고
    • Hawthorn (shan zha) drink and its lowering effect on blood lipid levels in humans and rats
    • Chen, J.D., Wu, Y.Z., Tao, Z.L., Chen, Z.M., Liu, X.P., 1995. Hawthorn (shan zha) drink and its lowering effect on blood lipid levels in humans and rats. World Rev. Nutr. Diet 77, 147-154.
    • (1995) World Rev. Nutr. Diet , vol.77 , pp. 147-154
    • Chen, J.D.1    Wu, Y.Z.2    Tao, Z.L.3    Chen, Z.M.4    Liu, X.P.5
  • 13
  • 14
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald, W.T., Levy, R.I., Fredrickson, D.S., 1972. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18, 499-502.
    • (1972) Clin. Chem. , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 15
    • 0027271799 scopus 로고
    • Killing of endothelial cells and release of arachidonic acid. Synergistic effects among hydrogen peroxide, membrane-damaging agents, cationic substances, and proteinases and their modulation by inhibitors
    • Ginsburg, I., Mitra, R.S., Gibbs, D.F., Varani, J., Kohen, R., 1993. Killing of endothelial cells and release of arachidonic acid. Synergistic effects among hydrogen peroxide, membrane-damaging agents, cationic substances, and proteinases and their modulation by inhibitors. Inflammation 17, 295-319.
    • (1993) Inflammation , vol.17 , pp. 295-319
    • Ginsburg, I.1    Mitra, R.S.2    Gibbs, D.F.3    Varani, J.4    Kohen, R.5
  • 17
    • 56349134577 scopus 로고    scopus 로고
    • The efficacy and safety of Crataegus extract WS® 1442 in patients with heart failure: The SPICE trial
    • Holubarsch, C.J.F., Colucci, W.S., Meinertz, T., Gaus, W., Tendera, M., 2008. The efficacy and safety of Crataegus extract WS® 1442 in patients with heart failure: the SPICE trial. Eur. J. Heart Fail. 10, 1255-1263.
    • (2008) Eur. J. Heart Fail. , vol.10 , pp. 1255-1263
    • Holubarsch, C.J.F.1    Colucci, W.S.2    Meinertz, T.3    Gaus, W.4    Tendera, M.5
  • 19
    • 21344458411 scopus 로고    scopus 로고
    • 2005. JACC 46, 184-221.
    • (2005) JACC , vol.46 , pp. 184-221
  • 20
    • 33750733952 scopus 로고    scopus 로고
    • Pretreatment with alcoholic extract of Crataegus oxyacantha (AEC) activates mitochondrial protection during isoproterenol-induced myocardial infarction in rats
    • Jayalakshmi, R., Thirupurasunduri, C.J., Devaraj, S.N., 2006. Pretreatment with alcoholic extract of Crataegus oxyacantha (AEC) activates mitochondrial protection during isoproterenol-induced myocardial infarction in rats. Mol. Cell. Biochem. 292, 59-67.
    • (2006) Mol. Cell. Biochem. , vol.292 , pp. 59-67
    • Jayalakshmi, R.1    Thirupurasunduri, C.J.2    Devaraj, S.N.3
  • 21
    • 0029449685 scopus 로고
    • PHARMAKOLOGISCHES WIRKPOFIL VON CRATAEGUS-EXTRAKT IM VERGLEICH ZU EPINEPHRIN, AMRINON, MILRINON UND DIGOXIN AM ISOLIERT PERFUNDIERTEN MEERSCHWEINCHENHERZEN
    • Joseph, G., Zhao, Y., Klaus, W., 1995. Pharmacologic action profile of Crataegus extract in comparison to epinephrine, amrinone, milrinone and digoxin in the isolated perfused guinea pig heart. Arzneimittelforschung 45, 1261-1265. (Pubitemid 26022260)
    • (1995) Arzneimittel-Forschung/Drug Research , vol.45 , Issue.12 , pp. 1261-1265
    • Joseph, G.1    Zhao, Y.2    Klaus, W.3
  • 22
    • 0027717419 scopus 로고
    • Production of flavonoids in cell cultures of Crataegus monogyna
    • DOI 10.1055/s-2006-959756
    • Kartnig, T., Kögl, G., Heydel, B., 1993. Production of flavonoids in cell cultures of Crataegus monogyna. Planta Med. 59, 537-538. (Pubitemid 24019544)
    • (1993) Planta Medica , vol.59 , Issue.6 , pp. 537-538
    • Kartnig, T.1    Kogl, G.2    Heydel, B.3
  • 23
    • 33846250034 scopus 로고    scopus 로고
    • Secretory phospholipases A2 stimulate mucus secretion, induce airway inflammation, and produce secretory hyperresponsiveness to neutrophil elastase in ferret trachea
    • Kosuke, O., Kim, J.S., Rubin Bruce, K., 2007. Secretory phospholipases A2 stimulate mucus secretion, induce airway inflammation, and produce secretory hyperresponsiveness to neutrophil elastase in ferret trachea. Am. J. Physiol. Lung Cell. Mol. Physiol. 292, L62-L67.
    • (2007) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.292
    • Kosuke, O.1    Kim, J.S.2    Rubin Bruce, K.3
  • 24
    • 0033982888 scopus 로고    scopus 로고
    • Neutrophilia and congestive heart failure after acute myocardial infarction
    • Kyne, L., Hausdorff, J.M., Knight, E., Dukas, L., Azhar, G., Wei, J.Y., 2000. Neutrophilia and congestive heart failure after acute myocardial infarction. Am. Heart J. 139 (1 Pt 1), 94-100.
    • (2000) Am. Heart J. , vol.139 , Issue.1 PART 1 , pp. 94-100
    • Kyne, L.1    Hausdorff, J.M.2    Knight, E.3    Dukas, L.4    Azhar, G.5    Wei, J.Y.6
  • 25
    • 0033056463 scopus 로고    scopus 로고
    • The cell biology of leukocyte-mediated proteolysis
    • Owen, C.A., Campbell, E.J., 1999. The cell biology of leukocyte-mediated proteolysis. J. Leukoc. Biol. 65, 137-150.
    • (1999) J. Leukoc. Biol. , vol.65 , pp. 137-150
    • Owen, C.A.1    Campbell, E.J.2
  • 26
    • 0029005276 scopus 로고
    • Traditional Chinese medicine in treatment of hyperlipidaemia
    • La Cour, B., Molgaard, P., Yi, Z., 1995. Traditional Chinese medicine in treatment of hyperlipidaemia. J. Ethnopharmacol. 46, 125-129.
    • (1995) J. Ethnopharmacol. , vol.46 , pp. 125-129
    • La Cour, B.1    Molgaard, P.2    Yi, Z.3
  • 28
    • 34848881273 scopus 로고    scopus 로고
    • Low plasma levels of HSP70 in patients with carotid atherosclerosis are associated with increased levels of proteolytic markers of neutrophil activation
    • DOI 10.1016/j.atherosclerosis.2006.10.030, PII S0021915006006599
    • Martin-Ventura, J.L., Leclercq, A., Blanco-Colio, L.M., Egido, J., Rossignol, P., Meilhac, O., Michel, J.B., 2007. Low plasma levels of HSP70 in patients with carotid atherosclerosis are associated with increased levels of proteolytic markers of neutrophil activation. Atherosclerosis 194, 334-341. (Pubitemid 47513095)
    • (2007) Atherosclerosis , vol.194 , Issue.2 , pp. 334-341
    • Martin-Ventura, J.L.1    Leclercq, A.2    Blanco-Colio, L.M.3    Egido, J.4    Rossignol, P.5    Meilhac, O.6    Michel, J.-B.7
  • 29
    • 2342432385 scopus 로고    scopus 로고
    • Complementary and alternative medicine in cardiovascular disease: A review of biologically based approaches
    • Miller, K.L., Liebowitz, R.S., Newby, L.K., Durham,M.H.S., 2004. Complementary and alternative medicine in cardiovascular disease: a review of biologically based approaches. Am. Heart J. 147, 401-411.
    • (2004) Am. Heart J. , vol.147 , pp. 401-411
    • Miller, K.L.1    Liebowitz, R.S.2    Newby, L.K.3    Durham, M.H.S.4
  • 31
    • 33846796357 scopus 로고    scopus 로고
    • Consumption of flavanol-rich cocoa acutely increases microcirculation in human skin
    • Neukam, K., Stalh, W., Tronnier, H., Sies, H., Heinrich, U., 2007. Consumption of flavanol-rich cocoa acutely increases microcirculation in human skin. Eur. J. Nutr. 46, 53-56.
    • (2007) Eur. J. Nutr. , vol.46 , pp. 53-56
    • Neukam, K.1    Stalh, W.2    Tronnier, H.3    Sies, H.4    Heinrich, U.5
  • 32
    • 0035371222 scopus 로고    scopus 로고
    • Antioxidant enzyme activities and the production of MDA and 8-oxo-DG in chronic lymphocytic leukaemia
    • Oltra, A., Carbonell, F., Tormos, C., Iradi, A., Sáez, G.T., 2001. Antioxidant enzyme activities and the production of MDA and 8-oxo-DG in chronic lymphocytic leukaemia. Free Radic. Biol. Med. 30, 1286-1292.
    • (2001) Free Radic. Biol. Med. , vol.30 , pp. 1286-1292
    • Oltra, A.1    Carbonell, F.2    Tormos, C.3    Iradi, A.4    Sáez, G.T.5
  • 33
    • 33745559712 scopus 로고    scopus 로고
    • Neutrophil serine proteases: Specific regulators of inflammation
    • Pham, C.T., 2006. Neutrophil serine proteases: specific regulators of inflammation. Nat. Rev. Immunol. 6, 541-550.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 541-550
    • Pham, C.T.1
  • 34
    • 0037938807 scopus 로고    scopus 로고
    • Hawthorn extract for treating heart failure: Meta-analysis of randomized heart trials
    • Pittler, M.H., Schmidt, K., Ernst, 2003. Hawthorn extract for treating heart failure: meta-analysis of randomized heart trials. Am. J. Med. 114, 665-674.
    • (2003) Am. J. Med. , vol.114 , pp. 665-674
    • Pittler, M.H.1    Schmidt, K.2    Ernst3
  • 35
    • 0034500249 scopus 로고    scopus 로고
    • Concentration of leukocyte elastase in plasma and polymorphonuclear neutrophil extracts in type 2 diabetes
    • Piwowar, A., Knapik-Kordecka, M., Warwas, M., 2000. Concentration of leukocyte elastase in plasma and polymorphonuclear neutrophil extracts in type 2 diabetes. Clin. Chem. Lab. Med. 38, 1257-1261.
    • (2000) Clin. Chem. Lab. Med. , vol.38 , pp. 1257-1261
    • Piwowar, A.1    Knapik-Kordecka, M.2    Warwas, M.3
  • 36
    • 0028793882 scopus 로고
    • Effect of hawthorn extract on contraction and energy turnover of isolated rat cardiomyocites
    • Pöpping, S., Rose, H., Ionescu, I., Fischer, Y., Kammermeier, H., 1995. Effect of hawthorn extract on contraction and energy turnover of isolated rat cardiomyocites. Arzneimittelforschung 45, 1157-1161.
    • (1995) Arzneimittelforschung , vol.45 , pp. 1157-1161
    • Pöpping, S.1    Rose, H.2    Ionescu, I.3    Fischer, Y.4    Kammermeier, H.5
  • 38
    • 0029949399 scopus 로고    scopus 로고
    • Effect of tincture of Crataegus on the LDL-receptor activity of hepatic plasma membrane of rats fed an atherogenic diet
    • DOI 10.1016/0021-9150(96)05813-3
    • Rajendran, S., Deepalakshmi, P.D., Parasakthy, K., Devaraj, H., Devaraj, S.N., 1996. Effect of tincture of Crataegus on the LDL-receptor activity of plasma membrane of rats fed an atherogenic diet. Atherosclerosis 123, 235-241. (Pubitemid 26175078)
    • (1996) Atherosclerosis , vol.123 , Issue.1-2 , pp. 235-241
    • Rajendran, S.1    Deepalakshmi, P.D.2    Parasakthy, K.3    Devaraj, H.4    Devaraj, S.N.5
  • 39
    • 0032710356 scopus 로고    scopus 로고
    • Clinical efficacy of an automated high-sensitivity C-reactive protein assay
    • Rifai, N., Tracy, R.P., Ridker, P.M., 1999. Clinical efficacy of an automated high-sensitivity C-reactive protein assay. Clin. Chem. 45, 2136-2141.
    • (1999) Clin. Chem. , vol.45 , pp. 2136-2141
    • Rifai, N.1    Tracy, R.P.2    Ridker, P.M.3
  • 42
    • 0034783941 scopus 로고    scopus 로고
    • Activation of progelatinase (MMP-2) by neutrophil elastase, cathepsin G, and proteinase-3: A role for inflammatory cells in tumor invasion and angiogenesis
    • Shamamian, P., Schwartz, J.D., Pocock, B., Monea, S., Whiting, D., Marcus, S.G., Mignatti, P., 2001. Activation of progelatinase (MMP-2) by neutrophil elastase, cathepsin G, and proteinase-3: a role for inflammatory cells in tumor invasion and angiogenesis. J. Cell. Physiol. 189, 197-201.
    • (2001) J. Cell. Physiol. , vol.189 , pp. 197-201
    • Shamamian, P.1    Schwartz, J.D.2    Pocock, B.3    Monea, S.4    Whiting, D.5    Marcus, S.G.6    Mignatti, P.7
  • 45
    • 0036267583 scopus 로고    scopus 로고
    • Efficacy and safety of Crataegus extract WS 1442 in comparison with placebo in patients with chronic stableNewYork Heart Association class-III heart failure
    • Tauchert, M., 2002. Efficacy and safety of Crataegus extract WS 1442 in comparison with placebo in patients with chronic stableNewYork Heart Association class-III heart failure. Am. Heart J. 143, 910-915.
    • (2002) Am. Heart J. , vol.143 , pp. 910-915
    • Tauchert, M.1
  • 46
    • 69249146586 scopus 로고    scopus 로고
    • Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants
    • Tring, T.S., Hili, P., Naughton, D.P., 2009. Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants. BMC Complement. Altern. Med. 9, 27.
    • (2009) BMC Complement. Altern. Med. , vol.9 , pp. 27
    • Tring, T.S.1    Hili, P.2    Naughton, D.P.3
  • 47
    • 34247526815 scopus 로고    scopus 로고
    • Relative value of inflammatory, hemostatic, and rheological factors for incident myocardial infarction and stroke: The Edinburgh artery study
    • DOI 10.1161/CIRCULATIONAHA.106.635029
    • Tzoulaki, I., Murray, G.D., Lee, A.J., Rumley, A., Lowe, G., Fowkes, G., 2007. Relative value of inflammatory, haemostatic and rheological factors for incident myocardial infarction and stroke. The Edinburgh Artery Study. Circulation 115, 2119-2127. (Pubitemid 46659063)
    • (2007) Circulation , vol.115 , Issue.16 , pp. 2119-2127
    • Tzoulaki, I.1    Murray, G.D.2    Lee, A.J.3    Rumley, A.4    Lowe, G.D.O.5    Fowkes, F.G.R.6
  • 48
    • 0842324493 scopus 로고    scopus 로고
    • Crataegus special extract WS® 1442 improves cardiac function and reduces infarct size in a rat model of prolonged coronary ischemia and reperfusion
    • DOI 10.1016/j.lfs.2003.09.050
    • Veveris, M., Koch, E., Chatterjee, S.S., 2004. Crataegus special extract WS® 1442 improves cardiac function and reduces infarct size in a rat model of prolonged coronary ischemia and reperfusion. Life Sci. 27, 1945-1955. (Pubitemid 38167562)
    • (2004) Life Sciences , vol.74 , Issue.15 , pp. 1945-1955
    • Veveris, M.1    Koch, E.2    Chatterjee, S.S.3
  • 50
    • 0029796091 scopus 로고    scopus 로고
    • Crataegus special extract WS 1442. Assessment of objective effectiveness in patients with heart failure (NYHA II)
    • Weikl, A., Assmus, K.D., Neukum-Schmidt, A., Schmitz, J., Zapfe jun, G., Noh, H.S., Siegrist, J., 1996. Crataegus special extract WS 1442. Assessment of objective effectiveness in patients with heart failure (NYHA II). Fortschr. Med. 114, 291-296.
    • (1996) Fortschr. Med. , vol.114 , pp. 291-296
    • Weikl, A.1    Assmus, K.D.2    Neukum-Schmidt, A.3    Schmitz, J.4    Zapfe Jr., G.5    Noh, H.S.6    Siegrist, J.7
  • 51
    • 16244397365 scopus 로고    scopus 로고
    • Neutrophil serine proteases: Potential key regulators of cell signalling during inflammation
    • Wiedow, O., Meyer-Hoffert, U., 2005. Neutrophil serine proteases: potential key regulators of cell signalling during inflammation. J. Intern. Med. 257, 319-328.
    • (2005) J. Intern. Med. , vol.257 , pp. 319-328
    • Wiedow, O.1    Meyer-Hoffert, U.2
  • 52
    • 0023201142 scopus 로고
    • Lipoperoxides in plasma asmeasured by liquid-chromatography: Separation of malondialdehyde-thiobarbituric acid adduct
    • Wong, S.H.Y., Knight, J.A., Hopfer, S.M., Zaharia, O., Leach Jr., C.N., Sunderman Jr., F.W., 1987. Lipoperoxides in plasma asmeasured by liquid-chromatography: separation of malondialdehyde-thiobarbituric acid adduct. Clin. Chem. 33, 214-220.
    • (1987) Clin. Chem. , vol.33 , pp. 214-220
    • Wong, S.H.Y.1    Knight, J.A.2    Hopfer, S.M.3    Zaharia, O.4    Leach Jr., C.N.5    Sunderman Jr., F.W.6
  • 53
    • 0038404499 scopus 로고    scopus 로고
    • Use of complementary and alternative medical therapies in patients with cardiovascular disease
    • Wood, M.J., Stewart, R.L., Merry, H., Johnstone, D.E., Cox, J.L., 2003. Use of complementary and alternative medical therapies in patients with cardiovascular disease. Am. Heart J. 145, 806-812.
    • (2003) Am. Heart J. , vol.145 , pp. 806-812
    • Wood, M.J.1    Stewart, R.L.2    Merry, H.3    Johnstone, D.E.4    Cox, J.L.5
  • 54
    • 0034882022 scopus 로고    scopus 로고
    • Clinical efficacy of Crataegus extract WS 1442 in congestive heart failure NYHA class II
    • Zapfe jun, G., 2001. Clinical efficacy of Crataegus extract WS 1442 in congestive heart failure NYHA class II. Phytomedicine 8, 262-266.
    • (2001) Phytomedicine , vol.8 , pp. 262-266
    • Zapfe Jr., G.1


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