Comparative effects of Aegle marmelos extract and alpha-tocopherol on serum lipids, lipid peroxides and cardiac enzyme levels in rats with isoproterenol-induced myocardial infarction

Singapore Medical Journal

Volumn 46, Issue 2, 2005, Pages 78-81

  Rajadurai, M ^a   Prince, P Stanely Mainzen ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Aegle marmelos; Isoproterenol; Lipids; Lipoproteins; Myocardial infarction

Indexed keywords

AEGLE MARMELOS EXTRACT; ALPHA TOCOPHEROL; CHOLESTEROL; CREATINE KINASE; DIGITONIN; FATTY ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ISOPRENALINE; LACTATE DEHYDROGENASE; LIPID PEROXIDE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PHOSPHOLIPID; PLANT EXTRACT; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

AEGLE; AEGLE MARMELOS; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; HEART INFARCTION; HEART MUSCLE; HEART PROTECTION; LIPID BLOOD LEVEL; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PLANT LEAF; RAT; TREATMENT OUTCOME;

ADRENERGIC BETA-AGONISTS; AEGLE; ALPHA-TOCOPHEROL; ANIMALS; ANTIOXIDANTS; BIOLOGICAL MARKERS; FEMALE; ISOPROTERENOL; LIPID PEROXIDES; LIPIDS; MYOCARDIAL INFARCTION; PHYTOTHERAPY; PLANT LEAVES; RATS; RATS, WISTAR;

EID: 13444253027     PISSN: 00375675     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Wexler BC, Greenberg BP. Protective effects of clofibrate on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats. Atherosclerosis 1978; 29:373-95.
2. Singal PK, Kapur N, Dhillon KS, Beamish RE, Dhalla NS. Role of free radicals in catecholamine-induced cardiomyopathy. Can J Physiol Pharmacol 1982; 60:1390-7.
3. Wexler BC. Myocardial infarction in young versus old male rats: pathophysiological changes. Am Heart J 1978; 96:70-80.
4. Kirtikar KR, Basu BD. Indian Medicinal Plants. 2nd ed. New Delhi: Periodical Experts Books Agency, 1993: 499-505.
5. Haravey SK. A preliminary communication of the action of Aegle marmelos (Bael) on heart. Indian J Med Res 1968; 56:327-31.
6. Rajadurai M, Padmanabhan M, Prince PSM. Effect of Aegle marmelos leaf extract and α-tocopherol on lipid peroxidation and antioxidants in isoproterenol induced myocardial infarction in rats. Cardiol 2005; 1:40-5.
7. Paritha IA, Devi CS. Effect of α-tocopherol on lipid peroxidation in isoproterenol induced myccardial infarction in rats. Indian J Physiol Pharmacol 1997; 41:369-70.
8. Okinaka S, Kumagai H, Ebashi S, Sugita H, Momoi H, Toyokura Y, et al. Serum creatine phosphokinase. Activity in progressive muscular dystrophy and neuromuscular diseases. Arch Neurol 1961; 4:520-5
9. King J, ed. The dehydrogenases or oxidoreductatses. Lactate dehydrogenase In: Practical Clinical Enzymology. London: Van Nostrand, 1965:106.
10. Yagi K. Lipid peroxides and human diseases. Chem Phys Lipids 1987; 45:337-51.
11. Jiang ZY, Hunt JV, Wolff SP. Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxide in low-density lipoprotein. Anal Biochem 1992; 202:384-89.
12. Zlatkis A, Zak B, Boyle AJ. A new method for the direct determination of serum cholesterol. J Lab Clin Med 1953; 41:486-92.
13. Varley H, Gowenlock AH, Bell M. Determination of free and ester cholesterol. In: Varley H, ed. Practical Clinical Biochemistry. New Delhi: CBS Publishers, 1991:311-6.
14. Foster LB, Dunn RT. Stable reagents for determination of serum triglycerides by a colorimetric Hantsch condensation method. Clin Chem 1973; 19:338-40.
15. Falholt K, Lund B, Falholt W. An easy colorimetric micro-method for routine determination of free fatty acids in plasma. Clin Chim Acta 1973; 46:105-11.
16. Zilversmit BB, Davis AK. Micro-determination of plasma phospholipids by TCA precipitation. J Lab Clin Med 1950; 35:155-61.
17. Wilson DE, Spiger MJ. A dual precipitation method for quantitative plasma lipoprotein measurement without ultra-centrifugation. J Lab Clin Med 1973; 82:473-82.
18. Rastogi RP, Mehrotra BN, eds. Aegle marmelos In: Compendium of Indian Medicinal Plants. New Delhi: Publication and Information Directorate, 1991: 17-21.
19. Hamberg M, Svensson J, Wakabayashi T, Samuelsson B. Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation. Proc Natl Acad Sci 1974; 71:345-9.
20. Paritha IA, Devi CS. Effect of α-tocopherol on isoproterenol- induced changes in lipid and lipoprotein profile in rats. Indian J Pharmacol 1997; 29:399-404.
21. Buring JE, O'Connor GT, Goldhaber SZ, Rosner B, Herbert PN, Blum CB, et al. Decreased HDL-2 and HDL-3 cholesterol, Apo A-I and Apo A-II and increased risk of myocardial infarction. Circulation 1992; 85:22-9.
22. Sheela SC, Devi CS. Effect of abana pretreatment on isoproterenol-induced hyperlipidaemia in rats. Indian J Pharmacol 2001; 63:101-4.
23. Chien KR, Sherman SC, Mittnacht S Jr, Farber JL. Arch Biochem Biophys 1980; 205:614-22.
24. Mathew S, Menon PVG, Kurup PA. Changes in myocardial and aortic lipids, lipolytic activity and fecal excretion of sterols and bile acids in isoproterenol-induced myocardial infarction in rats. Indian J Biochem Biophys 1981; 18:131-3.
25. Freedman DS, Gruchovv HW, Anderson AJ, Rimm AA, Barboriak JJ. Relation of triglyceride levels to coronary artery disease: the Milwaukee Cardiovascular Data Registry. Am J Epidemiol 1988; 127:1118-30.