메뉴 건너뛰기




Volumn 7, Issue 2, 2014, Pages 215-226

DAMPs activating innate and adaptive immune responses in COPD

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADVANCED GLYCATION END PRODUCT RECEPTOR; ALPHA DEFENSIN; BETA DEFENSIN; CALRETICULIN; CATHELICIDIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CELL PROTEIN; CIGARETTE SMOKE; FIBRONECTIN; FORMYLMETHIONINE; FORMYLPEPTIDE RECEPTOR; GALECTIN; GALECTIN 1; GALECTIN 3; HEAT SHOCK PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN; HYALURONIC ACID; MITOCHONDRIAL DNA; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN S 100; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2Y2 RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; VERSICAN;

EID: 84895083345     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2013.77     Document Type: Review
Times cited : (142)

References (148)
  • 1
    • 33748677876 scopus 로고    scopus 로고
    • Global burden of COPD: Systematic review and metaanalysis
    • Halbert, R.J. et al. Global burden of COPD: Systematic review and metaanalysis. Eur. Respir. J. 28, 523-532 (2006).
    • (2006) Eur. Respir. J. , vol.28 , pp. 523-532
    • Halbert, R.J.1
  • 2
    • 0003661906 scopus 로고    scopus 로고
    • World Health Organisation. WHO
    • World Health Organisation. WHO. World Health Statistics http:// www.who.int/whois/whostat/EN-WHS08-Full.pdf2008).
    • World Health Statistics
  • 3
    • 0141928029 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: Molecular and cellular mechanisms
    • Barnes, P.J., Shapiro, S.D. & Pauwels, R.A. Chronic obstructive pulmonary disease: Molecular and cellular mechanisms. Eur. Respir. J. 22, 672-688 (2003).
    • (2003) Eur. Respir. J. , vol.22 , pp. 672-688
    • Barnes, P.J.1    Shapiro, S.D.2    Pauwels, R.A.3
  • 4
    • 40049104892 scopus 로고    scopus 로고
    • Immunology of asthma and chronic obstructive pulmonary disease
    • Barnes, P.J. Immunology of asthma and chronic obstructive pulmonary disease. Nat. Rev. Immunol. 8, 183-192 (2008).
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 183-192
    • Barnes, P.J.1
  • 5
    • 80052706801 scopus 로고    scopus 로고
    • New insights into the immunology of chronic obstructive pulmonary disease
    • Brusselle, G.G., Joos, G.F. & Bracke, K.R. New insights into the immunology of chronic obstructive pulmonary disease. Lancet 378, 1015-1026 (2011).
    • (2011) Lancet , vol.378 , pp. 1015-1026
    • Brusselle, G.G.1    Joos, G.F.2    Bracke, K.R.3
  • 6
    • 0033822964 scopus 로고    scopus 로고
    • Indoor air pollution in developing countries: A major environmental and public health challenge
    • Bruce, N., Perez-Padilla, R. & Albalak, R. Indoor air pollution in developing countries: A major environmental and public health challenge. Bull. World Health Organ. 78, 1078-1092 (2000).
    • (2000) Bull. World Health Organ. , vol.78 , pp. 1078-1092
    • Bruce, N.1    Perez-Padilla, R.2    Albalak, R.3
  • 7
    • 33646554531 scopus 로고    scopus 로고
    • Inflammatory cells in the airways in COPD
    • O+Donnell, R., Breen, D.,Wilson, S. & Djukanovic, R. Inflammatory cells in the airways in COPD. Thorax 61, 448-454 (2006).
    • (2006) Thorax , vol.61 , pp. 448-454
    • Odonnell, R.1    Breen, D.2    Wilson, S.3    Djukanovic, R.4
  • 8
    • 66649127821 scopus 로고    scopus 로고
    • Immunologic aspects of chronic obstructive pulmonary disease
    • Cosio, M.G., Saetta, M. & Agusti, A. Immunologic aspects of chronic obstructive pulmonary disease. N. Engl. J. Med. 360, 2445-2454 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 2445-2454
    • Cosio, M.G.1    Saetta, M.2    Agusti, A.3
  • 9
    • 84870866845 scopus 로고    scopus 로고
    • GOLD guidelines 2011: What are the implications for primary care+
    • Gruffydd-Jones, K. GOLD guidelines 2011: What are the implications for primary care+ Prim. Care Respir. J. 21, 437-441 (2012).
    • (2012) Prim. Care Respir. J. , vol.21 , pp. 437-441
    • Gruffydd-Jones, K.1
  • 10
    • 35148862090 scopus 로고    scopus 로고
    • The immunopathogenesis of chronic obstructive pulmonary disease: Insights from recent research
    • Curtis, J.L., Freeman, C.M. & Hogg, J.C. The immunopathogenesis of chronic obstructive pulmonary disease: Insights from recent research. Proc. Am. Thorac. Soc. 4, 512-521 (2007).
    • (2007) Proc. Am. Thorac. Soc. , vol.4 , pp. 512-521
    • Curtis, J.L.1    Freeman, C.M.2    Hogg, J.C.3
  • 11
    • 0028201732 scopus 로고
    • Tolerance danger, and the extended family
    • Matzinger, P. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 12, 991-1045 (1994).
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 12
    • 84870564051 scopus 로고    scopus 로고
    • Apoptosis and necrosis: Two different outcomes of cigarette smoke condensate-induced endothelial cell death
    • Messner, B. et al. Apoptosis and necrosis: Two different outcomes of cigarette smoke condensate-induced endothelial cell death. Cell Death Dis. 3, e424 (2012).
    • (2012) Cell Death Dis. , vol.3
    • Messner, B.1
  • 13
    • 84874263775 scopus 로고    scopus 로고
    • Necroptosis: The release of damage-associated molecular patterns and its physiological relevance
    • Kaczmarek, A., Vandenabeele, P. & Krysko, D.V. Necroptosis: The release of damage-associated molecular patterns and its physiological relevance. Immunity 38, 209-223 (2013).
    • (2013) Immunity , vol.38 , pp. 209-223
    • Kaczmarek, A.1    Vandenabeele, P.2    Krysko, D.V.3
  • 14
    • 41149118513 scopus 로고    scopus 로고
    • How dying cells alert the immune system to danger
    • Kono, H. & Rock, K.L.How dying cells alert the immune system to danger. Nat. Rev. Immunol. 8, 279-289 (2008).
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 279-289
    • Kono, H.1    Rock, K.L.2
  • 15
    • 77956924042 scopus 로고    scopus 로고
    • Impairment of phagocytosis of apoptotic cells and its role in chronic airway diseases
    • Krysko, O., Vandenabeele, P., Krysko, D.V. & Bachert, C. Impairment of phagocytosis of apoptotic cells and its role in chronic airway diseases. Apoptosis 15, 1137-1146 (2010).
    • (2010) Apoptosis , vol.15 , pp. 1137-1146
    • Krysko, O.1    Vandenabeele, P.2    Krysko, D.V.3    Bachert, C.4
  • 16
    • 84883785469 scopus 로고    scopus 로고
    • The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunity
    • Gallo, P.M. & Gallucci, S. The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunity. Front. Immunol. 4, 138 (2013).
    • (2013) Front. Immunol. , vol.4 , pp. 138
    • Gallo, P.M.1    Gallucci, S.2
  • 17
    • 0035077330 scopus 로고    scopus 로고
    • Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema
    • Kasahara, Y. et al. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am. J. Respir. Crit. Care Med. 163, 737-744 (2001).
    • (2001) Am. J. Respir. Crit. Care Med. , vol.163 , pp. 737-744
    • Kasahara, Y.1
  • 18
    • 84864776533 scopus 로고    scopus 로고
    • Pathogenesis of chronic obstructive pulmonary disease
    • Tuder, R.M. & Petrache, I. Pathogenesis of chronic obstructive pulmonary disease. J. Clin. Invest. 122, 2749-2755 (2012).
    • (2012) J. Clin. Invest. , vol.122 , pp. 2749-2755
    • Tuder, R.M.1    Petrache, I.2
  • 19
    • 34447576406 scopus 로고    scopus 로고
    • Cigarette smoke-induced blockade of the mitochondrial respiratory chain switches lung epithelial cell apoptosis into necrosis
    • Van Der Toorn, M. et al. Cigarette smoke-induced blockade of the mitochondrial respiratory chain switches lung epithelial cell apoptosis into necrosis.Am. J. Physiol. Lung Cell.Mol. Physiol. 292, L1211-L1218 (2007).
    • (2007) Am. J. Physiol. Lung Cell.Mol. Physiol. , vol.292 , pp. 1211-1218
    • Van Der Toorn, M.1
  • 20
    • 84861435630 scopus 로고    scopus 로고
    • A perspective on mammalian caspases as positive and negative regulators of inflammation
    • Martin, S.J., Henry, C.M. & Cullen, S.P. A perspective on mammalian caspases as positive and negative regulators of inflammation. Mol. Cell 46, 387-397 (2012).
    • (2012) Mol. Cell , vol.46 , pp. 387-397
    • Martin, S.J.1    Henry, C.M.2    Cullen, S.P.3
  • 22
    • 84870239310 scopus 로고    scopus 로고
    • Immunogenic cell death and DAMPs in cancer therapy
    • Krysko, D.V. et al. Immunogenic cell death and DAMPs in cancer therapy. Nat. Rev. Cancer 12, 860-875 (2012).
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 860-875
    • Krysko, D.V.1
  • 23
    • 27844605402 scopus 로고    scopus 로고
    • Necrosis is associated with IL-6 production but apoptosis is not
    • Vanden Berghe, T. et al. Necrosis is associated with IL-6 production but apoptosis is not. Cell. Signal. 18, 328-335 (2006).
    • (2006) Cell. Signal. , vol.18 , pp. 328-335
    • Vanden Berghe, T.1
  • 24
    • 78649526394 scopus 로고    scopus 로고
    • Sterile inflammation: Sensing and reacting to damage
    • Chen, G.Y. & Nun+ ez, G. Sterile inflammation: Sensing and reacting to damage. Nat. Rev. Immunol. 10, 826-837 (2010).
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 826-837
    • Chen, G.Y.1    Nunez, G.2
  • 25
    • 77953446392 scopus 로고    scopus 로고
    • Dual role of heat shock proteins as regulators of apoptosis and innate immunity
    • Joly, A.-L., Wettstein, G.,Mignot,G., Ghiringhelli, F. & Garrido, C. Dual role of heat shock proteins as regulators of apoptosis and innate immunity. J. Innate Immun. 2, 238-247 (2010).
    • (2010) J. Innate Immun. , vol.2 , pp. 238-247
    • Joly, A.-L.1    Wettstein, G.2    Mignot, G.3    Ghiringhelli, F.4    Garrido, C.5
  • 26
    • 34848859541 scopus 로고    scopus 로고
    • Heat shock protein 70 (Hsp70): Membrane location, export and immunological relevance
    • Multhoff, G. Heat shock protein 70 (Hsp70): Membrane location, export and immunological relevance. Methods 43, 229-237 (2007).
    • (2007) Methods , vol.43 , pp. 229-237
    • Multhoff, G.1
  • 27
    • 0034353117 scopus 로고    scopus 로고
    • HSP70 peptidembearing and peptide-negative preparations act as chaperokines
    • Asea, A., Kabingu, E., Stevenson, M.A. & Calderwood, S.K. HSP70 peptidembearing and peptide-negative preparations act as chaperokines. Cell Stress Chaperones 5, 425-431 (2000).
    • (2000) Cell Stress Chaperones , vol.5 , pp. 425-431
    • Asea, A.1    Kabingu, E.2    Stevenson, M.A.3    Calderwood, S.K.4
  • 28
    • 84871070851 scopus 로고    scopus 로고
    • Danger associated molecular patterns (DAMPs) in acute lung injury
    • Tolle, L.B. & Standiford, T.J. Danger associated molecular patterns (DAMPs) in acute lung injury. J. Pathol. 229, 1-34 (2013).
    • (2013) J. Pathol. , vol.229 , pp. 1-34
    • Tolle, L.B.1    Standiford, T.J.2
  • 29
    • 0037177825 scopus 로고    scopus 로고
    • Novel signal transduction pathway utilized by extracellular HSP70: Role of toll-like receptor (TLR) 2 and TLR4
    • Asea, A. et al. Novel signal transduction pathway utilized by extracellular HSP70: Role of toll-like receptor (TLR) 2 and TLR4. J. Biol. Chem. 277, 15028-15034 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 15028-15034
    • Asea, A.1
  • 30
    • 0030863036 scopus 로고    scopus 로고
    • Induction of stress proteins by tobacco smoke in human monocytes: Modulation by antioxidants
    • Pinot, F., el Yaagoubi, A., Christie, P., Dinh-Xuan, A.T. & Polla, B.S. Induction of stress proteins by tobacco smoke in human monocytes: Modulation by antioxidants. Cell Stress Chaperones 2, 156-161 (1997).
    • (1997) Cell Stress Chaperones , vol.2 , pp. 156-161
    • Pinot, F.1    El Yaagoubi, A.2    Christie, P.3    Dinh-Xuan, A.T.4    Polla, B.S.5
  • 31
    • 63049085178 scopus 로고    scopus 로고
    • Elevated hsp27 hsp70 and hsp90 alpha in chronic obstructive pulmonary disease: Markers for immune activation and tissue destruction
    • Hacker, S. et al. Elevated HSP27, HSP70 and HSP90 alpha in chronic obstructive pulmonary disease: Markers for immune activation and tissue destruction. Clin. Lab. 55, 31-40 (2009).
    • (2009) Clin. Lab. , vol.55 , pp. 31-40
    • Hacker, S.1
  • 32
    • 82155182139 scopus 로고    scopus 로고
    • Convergent sets of data from in vivo and in vitro methods point to an active role of hsp60 in chronic obstructive pulmonary disease pathogenesis
    • Cappello, F. et al. Convergent sets of data from in vivo and in vitro methods point to an active role of hsp60 in chronic obstructive pulmonary disease pathogenesis. PLoS One 6, e28200 (2011).
    • (2011) PLoS One , vol.6
    • Cappello, F.1
  • 33
    • 80053223724 scopus 로고    scopus 로고
    • Dynamics of heat shock protein 60 in endothelial cells exposed to cigarette smoke extract
    • Kreutmayer, S.B. et al. Dynamics of heat shock protein 60 in endothelial cells exposed to cigarette smoke extract. J. Mol. Cell. Cardiol. 51, 777-780 (2011).
    • (2011) J. Mol. Cell. Cardiol. , vol.51 , pp. 777-780
    • Kreutmayer, S.B.1
  • 35
    • 0025900907 scopus 로고
    • Identification of p8,14as a highly abundant heterodimeric calcium binding protein complex of myeloid cells
    • Edgeworth, J., Gorman, M., Bennett, R., Freemont, P. & Hogg, N. Identification of p8,14as a highly abundant heterodimeric calcium binding protein complex of myeloid cells. J. Biol. Chem. 266, 7706-7713 (1991).
    • (1991) J. Biol. Chem. , vol.266 , pp. 7706-7713
    • Edgeworth, J.1    Gorman, M.2    Bennett, R.3    Freemont, P.4    Hogg, N.5
  • 36
    • 0030898101 scopus 로고    scopus 로고
    • Myeloid-related protein (MRP) 8 and MRP14, calciumbinding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathway
    • Rammes, A. et al. Myeloid-related protein (MRP) 8 and MRP14, calciumbinding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathway. J. Biol. Chem. 272, 9496-9502 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 9496-9502
    • Rammes, A.1
  • 37
    • 83555164774 scopus 로고    scopus 로고
    • S100A8 and S100A9: New insights into their roles in malignancy
    • Srikrishna, G. S100A8 and S100A9: New insights into their roles in malignancy. J. Innate Immun. 4, 31-40 (2012).
    • (2012) J. Innate Immun. , vol.4 , pp. 31-40
    • Srikrishna, G.1
  • 38
    • 23044450101 scopus 로고    scopus 로고
    • Proteomic study of human bronchoalveolar lavage fluids from smokers with chronic obstructive pulmonary disease by combining surface-enhanced laser desorption/ionization-mass spectrometry profiling with mass spectrometric protein identification
    • Merkel, D., Rist,W., Seither, P., Weith, A. & Lenter, M.C. Proteomic study of human bronchoalveolar lavage fluids from smokers with chronic obstructive pulmonary disease by combining surface-enhanced laser desorption/ionization-mass spectrometry profiling with mass spectrometric protein identification. Proteomics 5, 2972-2980 (2005).
    • (2005) Proteomics , vol.5 , pp. 2972-2980
    • Merkel, D.1    Rist, W.2    Seither, P.3    Weith, A.4    Lenter, M.C.5
  • 39
    • 40049100981 scopus 로고    scopus 로고
    • Different expression ratio of S100A8/A9 and S100A12 in acute and chronic lung diseases
    • Lorenz, E. et al. Different expression ratio of S100A8/A9 and S100A12 in acute and chronic lung diseases. Respir. Med. 102, 567-573 (2008).
    • (2008) Respir. Med. , vol.102 , pp. 567-573
    • Lorenz, E.1
  • 40
    • 79959778582 scopus 로고    scopus 로고
    • Soluble receptor for advanced glycation end products in COPD: Relationship with emphysema and chronic cor pulmonale: A casecontrol study
    • Miniati, M. et al. Soluble receptor for advanced glycation end products in COPD: Relationship with emphysema and chronic cor pulmonale: A casecontrol study. Respir. Res. 12, 37 (2011).
    • (2011) Respir. Res. , vol.12 , pp. 37
    • Miniati, M.1
  • 41
    • 84862203625 scopus 로고    scopus 로고
    • Systemic biomarkers of neutrophilic inflammation, tissue injury and repair in COPD patients with differing levels of disease severity
    • Cockayne, D.a. et al. Systemic biomarkers of neutrophilic inflammation, tissue injury and repair in COPD patients with differing levels of disease severity. PLoS One 7, e38629 (2012).
    • (2012) PLoS One , vol.7
    • Cockayne, D.A.1
  • 42
    • 77952307233 scopus 로고    scopus 로고
    • Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease
    • Ferhani, N. et al. Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 181, 917-927 (2010).
    • (2010) Am. J. Respir. Crit. Care Med. , vol.181 , pp. 917-927
    • Ferhani, N.1
  • 43
    • 79953687947 scopus 로고    scopus 로고
    • Reduced soluble receptor for advanced glycation endproducts in COPD
    • Smith, D.J. et al. Reduced soluble receptor for advanced glycation endproducts in COPD. Eur. Respir. J. 37, 516-522 (2011).
    • (2011) Eur. Respir. J. , vol.37 , pp. 516-522
    • Smith, D.J.1
  • 44
    • 84860324666 scopus 로고    scopus 로고
    • Soluble rage is deficient in neutrophilic asthma and copd
    • Sukkar, M.B. et al. Soluble RAGE is deficient in neutrophilic asthma and COPD. Eur. Respir. J. 39, 721-729 (2012).
    • (2012) Eur. Respir. J. , vol.39 , pp. 721-729
    • Sukkar, M.B.1
  • 45
    • 84867772903 scopus 로고    scopus 로고
    • RAGE: A new frontier in chronic airways disease
    • Sukkar,M.B. et al. RAGE: A new frontier in chronic airways disease. Br. J. Pharmacol., 1-37 (2012).
    • (2012) Br. J. Pharmacol. , pp. 1-37
    • Sukkar, M.B.1
  • 46
    • 73349111257 scopus 로고    scopus 로고
    • Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function
    • Hancock, D.B. et al. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat. Genet. 42, 45-52 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 45-52
    • Hancock, D.B.1
  • 47
    • 73349143302 scopus 로고    scopus 로고
    • Genome-wide association study identifies five loci associated with lung function
    • Repapi, E. et al. Genome-wide association study identifies five loci associated with lung function. Nat. Genet. 42, 36-44 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 36-44
    • Repapi, E.1
  • 48
    • 84860228899 scopus 로고    scopus 로고
    • Galectins in acute and chronic inflammation
    • Liu, F.-T., Yang, R.-Y. & Hsu, D.K. Galectins in acute and chronic inflammation. Ann. NY Acad. Sci. 1253, 80-91 (2012).
    • (2012) Ann. NY Acad. Sci. , vol.1253 , pp. 80-91
    • Liu, F.-T.1    Yang, R.-Y.2    Hsu, D.K.3
  • 49
    • 67649774331 scopus 로고    scopus 로고
    • Galectins in innate immunity: Dual functions of host soluble beta-galactoside-binding lectins as damage-associated molecular patterns (DAMPs) and as receptors for pathogen-associated molecular patterns (PAMPs)
    • Sato, S., St-Pierre, C., Bhaumik, P. & Nieminen, J. Galectins in innate immunity: Dual functions of host soluble beta-galactoside-binding lectins as damage-associated molecular patterns (DAMPs) and as receptors for pathogen-associated molecular patterns (PAMPs). Immunol. Rev. 230, 172-187 (2009).
    • (2009) Immunol. Rev. , vol.230 , pp. 172-187
    • Sato, S.1    St-Pierre, C.2    Bhaumik, P.3    Nieminen, J.4
  • 50
    • 75749101401 scopus 로고    scopus 로고
    • Galectins: Regulators of acute and chronic inflammation
    • Liu, F.-T. & Rabinovich, G.a. Galectins: Regulators of acute and chronic inflammation. Ann. NY Acad Sci. 1183, 158-182 (2010).
    • (2010) Ann. NY Acad Sci. , vol.1183 , pp. 158-182
    • Liu, F.-T.1    Rabinovich, G.A.2
  • 51
    • 84872177718 scopus 로고    scopus 로고
    • Galectin-3 facilitates neutrophil recruitment as an innate immune response to a parasitic protozoa cutaneous infection
    • Bhaumik, P., St-Pierre, G., Milot, V., St-Pierre, C. & Sato, S. Galectin-3 facilitates neutrophil recruitment as an innate immune response to a parasitic protozoa cutaneous infection. J. Immunol. 190, 630-640 (2012).
    • (2012) J. Immunol. , vol.190 , pp. 630-640
    • Bhaumik, P.1    St-Pierre, G.2    Milot, V.3    St-Pierre, C.4    Sato, S.5
  • 52
    • 34248231698 scopus 로고    scopus 로고
    • Increased galectin-3 expression and intra-epithelial neutrophils in small airways in severe COPD
    • Pilette, C. et al. Increased galectin-3 expression and intra-epithelial neutrophils in small airways in severe COPD. Eur. Respir. J. 29, 914-922 (2007).
    • (2007) Eur. Respir. J. , vol.29 , pp. 914-922
    • Pilette, C.1
  • 53
    • 79952756344 scopus 로고    scopus 로고
    • Dysregulation of TIM-3-galectin-9 pathway in the cystic fibrosis airways
    • Vega-Carrascal, I. et al. Dysregulation of TIM-3-galectin-9 pathway in the cystic fibrosis airways. J. Immunol. 186, 2897-2909 (2011).
    • (2011) J. Immunol. , vol.186 , pp. 2897-2909
    • Vega-Carrascal, I.1
  • 54
    • 80053605687 scopus 로고    scopus 로고
    • Antimicrobial peptides important in innate immunity
    • Cederlund, A., Gudmundsson, G.H. & Agerberth, B. Antimicrobial peptides important in innate immunity. FEBS J. 278, 3942-3951 (2011).
    • (2011) FEBS J. , vol.278 , pp. 3942-3951
    • Cederlund, A.1    Gudmundsson, G.H.2    Agerberth, B.3
  • 55
    • 0141799911 scopus 로고    scopus 로고
    • Defensins: Antimicrobial peptides of innate immunity
    • Ganz, T. Defensins: Antimicrobial peptides of innate immunity. Nat. Rev. Immunol. 3, 710-720 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 710-720
    • Ganz, T.1
  • 56
    • 79952339508 scopus 로고    scopus 로고
    • Dangers within: DAMP responses to damage and cell death in kidney disease
    • Rosin, D.L. & Okusa, M.D. Dangers within: DAMP responses to damage and cell death in kidney disease. J.Am. Soc.Nephrol. 22, 416-425 (2011).
    • (2011) J.Am. Soc.Nephrol. , vol.22 , pp. 416-425
    • Rosin, D.L.1    Okusa, M.D.2
  • 57
    • 44449154973 scopus 로고    scopus 로고
    • Murine beta-defensin 2 promotes TLR-4/MyD88-mediated and NF-kappaB-dependent atypical death of APCs via activation of TNFR2
    • Biragyn, A. et al. Murine beta-defensin 2 promotes TLR-4/MyD88-mediated and NF-kappaB-dependent atypical death of APCs via activation of TNFR2. J. Leukoc. Biol. 83, 998-1008 (2008).
    • (2008) J. Leukoc. Biol. , vol.83 , pp. 998-1008
    • Biragyn, A.1
  • 58
    • 0034201213 scopus 로고    scopus 로고
    • Neutrophil alpha-defensin human neutrophil peptide modulates cytokine production in human monocytes and adhesion molecule expression in endothelial cells
    • Chaly, Y.V. et al. Neutrophil alpha-defensin human neutrophil peptide modulates cytokine production in human monocytes and adhesion molecule expression in endothelial cells. Eur.Cytokine Netw. 11, 257-266 (2000).
    • (2000) Eur.Cytokine Netw. , vol.11 , pp. 257-266
    • Chaly, Y.V.1
  • 59
    • 0033844287 scopus 로고    scopus 로고
    • Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells
    • Yang, D., Chen, Q., Chertov, O. & Oppenheim, J.J. Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells. J. Leukoc. Biol. 68, 9-14 (2000).
    • (2000) J. Leukoc. Biol. , vol.68 , pp. 9-14
    • Yang, D.1    Chen, Q.2    Chertov, O.3    Oppenheim, J.J.4
  • 60
    • 0036161872 scopus 로고    scopus 로고
    • Neutrophil defensins stimulate the release of cytokines by airway epithelial cells: Modulation by dexamethasone
    • Van Wetering, S., Mannesse-Lazeroms, S.P.G., Van Sterkenburg, M.A.J.A. & Hiemstra, P.S. Neutrophil defensins stimulate the release of cytokines by airway epithelial cells: Modulation by dexamethasone. Inflamm. Res. 51, 8-15 (2002).
    • (2002) Inflamm. Res. , vol.51 , pp. 8-15
    • Van Wetering, S.1    Mannesse-Lazeroms, S.P.G.2    Van Sterkenburg, M.A.J.A.3    Hiemstra, P.S.4
  • 61
    • 79960975572 scopus 로고    scopus 로고
    • Human neutrophil peptides sputum levels in symptomatic smokers and COPD patients
    • Paone, G. et al. Human neutrophil peptides sputum levels in symptomatic smokers and COPD patients. Eur. Rev. Med. Pharmacol. Sci. 15, 556-562 (2011).
    • (2011) Eur. Rev. Med. Pharmacol. Sci. , vol.15 , pp. 556-562
    • Paone, G.1
  • 62
    • 79960469576 scopus 로고    scopus 로고
    • Increased expression of beta-defensin 1 (DEFB1) in chronic obstructive pulmonary disease
    • Andresen, E.,Gu+nther,G., Bullwinkel, J., Lange, C. & Heine, H. Increased expression of beta-defensin 1 (DEFB1) in chronic obstructive pulmonary disease. PLoS One 6, e21898 (2011).
    • (2011) PLoS One , vol.6
    • Andresen, E.1    Gunther, G.2    Bullwinkel, J.3    Lange, C.4    Heine, H.5
  • 63
    • 78650177220 scopus 로고    scopus 로고
    • TLR4 upregulation underpins airway neutrophilia in smokers with chronic obstructive pulmonary disease and acute respiratory failure
    • Pace, E. et al. TLR4 upregulation underpins airway neutrophilia in smokers with chronic obstructive pulmonary disease and acute respiratory failure. Hum. Immunol. 72, 54-62 (2011).
    • (2011) Hum. Immunol. , vol.72 , pp. 54-62
    • Pace, E.1
  • 64
    • 77955002672 scopus 로고    scopus 로고
    • Innate immunity proteins in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis
    • Tsoumakidou, M., Bouloukaki, I., Thimaki, K., Tzanakis, N. & Siafakas, N.M. Innate immunity proteins in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. Exp. Lung Res. 36, 373-380 (2010).
    • (2010) Exp. Lung Res. , vol.36 , pp. 373-380
    • Tsoumakidou, M.1    Bouloukaki, I.2    Thimaki, K.3    Tzanakis, N.4    Siafakas, N.M.5
  • 65
    • 77956580787 scopus 로고    scopus 로고
    • Cigarette smoke enhances {beta}-defensin 2 expression in rat airways via nuclear factor-{kappa}B activation
    • Chen, L. et al. Cigarette smoke enhances {beta}-defensin 2 expression in rat airways via nuclear factor-{kappa}B activation. Eur. Respir. J. 36, 638-645 (2010).
    • (2010) Eur. Respir. J. , vol.36 , pp. 638-645
    • Chen, L.1
  • 66
    • 84869239734 scopus 로고    scopus 로고
    • Changes in prevalence and load of airway bacteria using quantitative PCR in stable and exacerbated COPD
    • Garcha, D.S. et al. Changes in prevalence and load of airway bacteria using quantitative PCR in stable and exacerbated COPD. Thorax 67, 1075-1080 (2012).
    • (2012) Thorax , vol.67 , pp. 1075-1080
    • Garcha, D.S.1
  • 67
    • 84864977029 scopus 로고    scopus 로고
    • Viral infection is associated with an increased proinflammatory response in chronic obstructive pulmonary disease
    • Almansa, R. et al. Viral infection is associated with an increased proinflammatory response in chronic obstructive pulmonary disease. Viral Immunol. 25, 249-253 (2012).
    • (2012) Viral Immunol. , vol.25 , pp. 249-253
    • Almansa, R.1
  • 68
    • 0028844134 scopus 로고
    • Cathelicidins: A novel protein family with a common proregion and a variable C-terminal antimicrobial domain
    • Zanetti, M., Gennaro, R. & Romeo, D. Cathelicidins: A novel protein family with a common proregion and a variable C-terminal antimicrobial domain. FEBS Lett. 374, 1-5 (1995).
    • (1995) FEBS Lett. , vol.374 , pp. 1-5
    • Zanetti, M.1    Gennaro, R.2    Romeo, D.3
  • 69
    • 0029007198 scopus 로고
    • ECAP-18 a cathelin/probactenecin-like protein of human neutrophil specific granules
    • Cowland, J.B., Johnsen, A.H. & Borregaard, N. hCAP-18, a cathelin/probactenecin-like protein of human neutrophil specific granules. FEBS Lett. 368, 173-176 (1995).
    • (1995) FEBS Lett. , vol.368 , pp. 173-176
    • Cowland, J.B.1    Johnsen, A.H.2    Borregaard, N.3
  • 70
    • 0032482980 scopus 로고    scopus 로고
    • The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface
    • Bals, R. et al. The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface. Proc. Natl. Acad. Sci. USA 95, 9541-9546 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 9541-9546
    • Bals, R.1
  • 71
    • 0000450744 scopus 로고    scopus 로고
    • Antibacterial components in bronchoalveolar lavage fluid from healthy individuals and sarcoidosis patients
    • Agerberth, B. et al. Antibacterial components in bronchoalveolar lavage fluid from healthy individuals and sarcoidosis patients. Am. J. Respir. Crit. Care Med. 160, 283-290 (1999).
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , pp. 283-290
    • Agerberth, B.1
  • 72
    • 0036379140 scopus 로고    scopus 로고
    • Cathelicidins essential gene-encoded mammalian antibiotics
    • Zaiou, M. & Gallo, R.L. Cathelicidins, essential gene-encoded mammalian antibiotics. J. Mol. Med. 80, 549-561 (2002).
    • (2002) J. Mol. Med. , vol.80 , pp. 549-561
    • Zaiou, M.1    Gallo, R.L.2
  • 73
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi, O. & Akira, S. Pattern recognition receptors and inflammation. Cell 140, 805-820 (2010).
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 74
    • 79951786934 scopus 로고    scopus 로고
    • Novel sulfated polysaccharides disrupt cathelicidins, inhibit RAGE and reduce cutaneous inflammation in a mouse model of rosacea
    • Zhang, J. et al. Novel sulfated polysaccharides disrupt cathelicidins, inhibit RAGE and reduce cutaneous inflammation in a mouse model of rosacea. PLoS One 6, e16658 (2011).
    • (2011) PLoS One , vol.6
    • Zhang, J.1
  • 75
    • 33646586648 scopus 로고    scopus 로고
    • Human cathelicidin LL-37 is a chemoattractant for eosinophils and neutrophils that acts via formyl-peptide receptors
    • Tjabringa,G.S., Ninaber, D.K., Drijfhout, J.W., Rabe, K.F. &Hiemstra, P.S. Human cathelicidin LL-37 is a chemoattractant for eosinophils and neutrophils that acts via formyl-peptide receptors. Int. Arch. Allergy Immunol. 140, 103-112 (2006).
    • (2006) Int. Arch. Allergy Immunol. , vol.140 , pp. 103-112
    • Tjabringa, G.S.1    Ninaber, D.K.2    Drijfhout, J.W.3    Rabe, K.F.4    Hiemstra, P.S.5
  • 76
    • 27144468929 scopus 로고    scopus 로고
    • Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure
    • Shaykhiev, R. et al. Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure. Am. J. Physiol. 289, L842-L848 (2005)
    • (2005) Am. J. Physiol. , vol.289 , pp. 842-848
    • Shaykhiev, R.1
  • 77
    • 84867748126 scopus 로고    scopus 로고
    • The effect of human antibacterial peptide LL-37 in the pathogenesis of chronic obstructive pulmonary disease
    • Jiang, Y.-Y. et al. The effect of human antibacterial peptide LL-37 in the pathogenesis of chronic obstructive pulmonary disease. Respir. Med. 106, 1680-1689 (2012).
    • (2012) Respir. Med. , vol.106 , pp. 1680-1689
    • Jiang, Y.-Y.1
  • 78
    • 80052652326 scopus 로고    scopus 로고
    • Effects of bacterial infection on airway antimicrobial peptides and proteins in COPD
    • Parameswaran, G.I., Sethi, S. & Murphy, T.F. Effects of bacterial infection on airway antimicrobial peptides and proteins in COPD. Chest 140, 611-617 (2011).
    • (2011) Chest , vol.140 , pp. 611-617
    • Parameswaran, G.I.1    Sethi, S.2    Murphy, T.F.3
  • 79
    • 27144462218 scopus 로고    scopus 로고
    • Sputum cathelicidin, urokinase plasminogen activation system components, and cytokines discriminate cystic fibrosis, COPD, and asthma inflammation
    • Xiao, W., Hsu, Y.-P., Ishizaka, A., Kirikae, T. & Moss, R.B. Sputum cathelicidin, urokinase plasminogen activation system components, and cytokines discriminate cystic fibrosis, COPD, and asthma inflammation. Chest 128, 2316-2326 (2005).
    • (2005) Chest , vol.128 , pp. 2316-2326
    • Xiao, W.1    Hsu, Y.-P.2    Ishizaka, A.3    Kirikae, T.4    Moss, R.B.5
  • 80
    • 84876586828 scopus 로고    scopus 로고
    • Cathelicidin LL-37 in bronchoalveolar lavage and epithelial lining fluids from COPD patients and healthy individuals
    • Golec, M. et al. Cathelicidin LL-37 in bronchoalveolar lavage and epithelial lining fluids from COPD patients and healthy individuals. J. Biol. Regul. Homeost. Agents 26, 617-625 (2012).
    • (2012) J. Biol. Regul. Homeost. Agents , vol.26 , pp. 617-625
    • Golec, M.1
  • 82
    • 0034698830 scopus 로고    scopus 로고
    • High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes
    • Andersson, U. et al. High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J. Exp. Med. 192, 565-570 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 565-570
    • Andersson, U.1
  • 83
    • 33845333359 scopus 로고    scopus 로고
    • The extracellular release of HMGB1 during apoptotic cell death
    • Bell, C.W., Jiang, W., Reich, C.F. & Pisetsky, D.S. The extracellular release of HMGB1 during apoptotic cell death. Am. J. Physiol. 291, C1318-C1325 (2006).
    • (2006) Am. J. Physiol. , vol.291 , pp. 1318-1325
    • Bell, C.W.1    Jiang, W.2    Reich, C.F.3    Pisetsky, D.S.4
  • 84
    • 0036775236 scopus 로고    scopus 로고
    • The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway
    • Gardella, S. et al. The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway. EMBO Rep. 3, 995-1001 (2002).
    • (2002) EMBO Rep. , vol.3 , pp. 995-1001
    • Gardella, S.1
  • 85
    • 19944431800 scopus 로고    scopus 로고
    • RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages
    • Kokkola, R. et al. RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages. Scand. J. Immunol. 61, 1-9 (2005).
    • (2005) Scand. J. Immunol. , vol.61 , pp. 1-9
    • Kokkola, R.1
  • 86
    • 1542380035 scopus 로고    scopus 로고
    • Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
    • Park, J.S. et al. Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J. Biol. Chem. 279, 7370-7377 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 7370-7377
    • Park, J.S.1
  • 87
    • 84879582334 scopus 로고    scopus 로고
    • Alcohol-induced IL-1b in the brain is mediated by NLRP3/ ASC inflammasome activation that amplifies neuroinflammation
    • Lippai, D. et al. Alcohol-induced IL-1b in the brain is mediated by NLRP3/ ASC inflammasome activation that amplifies neuroinflammation. J. Leukoc. Biol. 94, 171-182 (2013).
    • (2013) J. Leukoc. Biol. , vol.94 , pp. 171-182
    • Lippai, D.1
  • 88
    • 70149084792 scopus 로고    scopus 로고
    • HMGB1 loves company
    • Bianchi, M.E. HMGB1 loves company. J. Leukoc. Biol. 86, 573-576 (2009).
    • (2009) J. Leukoc. Biol. , vol.86 , pp. 573-576
    • Bianchi, M.E.1
  • 89
    • 70149098507 scopus 로고    scopus 로고
    • The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation
    • Hreggvidsdottir, H.S. et al. The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation. J. Leukoc. Biol. 86, 655-662 (2009).
    • (2009) J. Leukoc. Biol. , vol.86 , pp. 655-662
    • Hreggvidsdottir, H.S.1
  • 90
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs, PAMPs and alarmins: All we need to know about danger
    • Bianchi, M.E. DAMPs, PAMPs and alarmins: All we need to know about danger. J. Leukoc. Biol. 81, 1-5 (2007).
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 1-5
    • Bianchi, M.E.1
  • 91
  • 92
    • 84869880290 scopus 로고    scopus 로고
    • High-mobility group box family of proteins: Ligand and sensor for innate immunity
    • Yanai, H., Ban, T. & Taniguchi, T. High-mobility group box family of proteins: Ligand and sensor for innate immunity. Trends Immunol. 33, 633-640 (2012).
    • (2012) Trends Immunol. , vol.33 , pp. 633-640
    • Yanai, H.1    Ban, T.2    Taniguchi, T.3
  • 93
    • 33845893860 scopus 로고    scopus 로고
    • Pivotal advance: Analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin)
    • Rouhiainen, A., Tumova, S., Valmu, L., Kalkkinen, N. & Rauvala, H. Pivotal advance: Analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin). J. Leukoc. Biol. 81, 49-58 (2007).
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 49-58
    • Rouhiainen, A.1    Tumova, S.2    Valmu, L.3    Kalkkinen, N.4    Rauvala, H.5
  • 94
    • 83455233679 scopus 로고    scopus 로고
    • Cell death in the pathogenesis of immune-mediated diseases: The role of HMGB1 and DAMP-PAMP complexes
    • Pisetsky, D. Cell death in the pathogenesis of immune-mediated diseases: The role of HMGB1 and DAMP-PAMP complexes. Swiss Med. Wkly. 141, w13256 (2011).
    • (2011) Swiss Med. Wkly. , vol.141 , pp. 13256
    • Pisetsky, D.1
  • 95
    • 84866378556 scopus 로고    scopus 로고
    • Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release
    • Venereau, E. et al. Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release. J. Exp. Med. 209, 1519-1528 (2012).
    • (2012) J. Exp. Med. , vol.209 , pp. 1519-1528
    • Venereau, E.1
  • 96
    • 84874640125 scopus 로고    scopus 로고
    • HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor
    • Tadie, J-M. et al. HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor. Am. J. Physiol. 304, L342-L349 (2013).
    • (2013) Am. J. Physiol. , vol.304 , pp. 342-349
    • Tadie, J.-M.1
  • 97
    • 79251585548 scopus 로고    scopus 로고
    • Smoke exposure as a determinant of autoantibody titre in a1-antitrypsin deficiency and COPD
    • Wood, A.M., de Pablo, P., Buckley, C.D., Ahmad, A. & Stockley, R.A. Smoke exposure as a determinant of autoantibody titre in a1-antitrypsin deficiency and COPD. Eur. Respir. J. 37, 32-38 (2011).
    • (2011) Eur. Respir. J. , vol.37 , pp. 32-38
    • Wood, A.M.1    De Pablo, P.2    Buckley, C.D.3    Ahmad, A.4    Stockley, R.A.5
  • 98
    • 79960726338 scopus 로고    scopus 로고
    • High mobility group protein B1 (HMGB1) in asthma: Comparison of patients with chronic obstructive pulmonary disease and healthy controls
    • Hou, C. et al. High mobility group protein B1 (HMGB1) in asthma: Comparison of patients with chronic obstructive pulmonary disease and healthy controls. Mol. Med. 17, 807-815 (2011).
    • (2011) Mol. Med. , vol.17 , pp. 807-815
    • Hou, C.1
  • 99
    • 84858277649 scopus 로고    scopus 로고
    • Validity of HMGB1 measurement in epithelial lining fluid in patients with COPD
    • Kanazawa, H. et al. Validity of HMGB1 measurement in epithelial lining fluid in patients with COPD. Eur. J. Clin. Invest. 42, 419-426 (2011).
    • (2011) Eur. J. Clin. Invest. , vol.42 , pp. 419-426
    • Kanazawa, H.1
  • 100
    • 79957443937 scopus 로고    scopus 로고
    • Long-term exposure to cigarette smoke impairs lung function and increases HMGB-1 expression in mice
    • Bezerra, F.S. et al. Long-term exposure to cigarette smoke impairs lung function and increases HMGB-1 expression in mice. Respir. Physiol. Neurobiol. 177, 120-126 (2011).
    • (2011) Respir. Physiol. Neurobiol. , vol.177 , pp. 120-126
    • Bezerra, F.S.1
  • 101
    • 76949108183 scopus 로고    scopus 로고
    • Green tea extract supplement inhibition of HMGB1 release in rats exposed to cigarette smoke
    • Saiwichai, T. et al. Green tea extract supplement inhibition of HMGB1 release in rats exposed to cigarette smoke. Southeast Asian J. Trop. Med. Public Health 41, 250-258 (2010).
    • (2010) Southeast Asian J. Trop. Med. Public Health , vol.41 , pp. 250-258
    • Saiwichai, T.1
  • 102
    • 75349083568 scopus 로고    scopus 로고
    • Immunogenic cell death DAMPs and anticancer therapeutics: An emerging amalgamation
    • Garg, A.D. et al. Immunogenic cell death, DAMPs and anticancer therapeutics: An emerging amalgamation. Biochim. Biophys. Acta 1805, 53-71 (2010).
    • (2010) Biochim. Biophys. Acta , vol.1805 , pp. 53-71
    • Garg, A.D.1
  • 103
    • 84857997683 scopus 로고    scopus 로고
    • A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
    • Garg, A.D. et al. A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death. EMBO J. 31, 1062-1079 (2012).
    • (2012) EMBO J. , vol.31 , pp. 1062-1079
    • Garg, A.D.1
  • 104
    • 62449131194 scopus 로고    scopus 로고
    • Immunogenic cell death modalities and their impact on cancer treatment
    • Kepp, O. et al. Immunogenic cell death modalities and their impact on cancer treatment. Apoptosis 14, 364-375 (2009).
    • (2009) Apoptosis , vol.14 , pp. 364-375
    • Kepp, O.1
  • 105
    • 26844468253 scopus 로고    scopus 로고
    • Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte
    • Gardai, S.J. et al. Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte. Cell 123, 321-334 (2005).
    • (2005) Cell , vol.123 , pp. 321-334
    • Gardai, S.J.1
  • 106
    • 84872191992 scopus 로고    scopus 로고
    • Cigarette smoke induces endoplasmic reticulum stress response and proteasomal dysfunction in human alveolar epithelial cells
    • Somborac-Bacura, A. et al. Cigarette smoke induces endoplasmic reticulum stress response and proteasomal dysfunction in human alveolar epithelial cells. Exp. Physiol. 98, 316-325 (2013).
    • (2013) Exp. Physiol. , vol.98 , pp. 316-325
    • Somborac-Bacura, A.1
  • 107
    • 51049112958 scopus 로고    scopus 로고
    • Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells
    • Jorgensen, E. et al. Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells. BMC Cancer 8, 229 (2008).
    • (2008) BMC Cancer , vol.8 , pp. 229
    • Jorgensen, E.1
  • 108
    • 72549115279 scopus 로고    scopus 로고
    • Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: The role of Nrf2-regulated proteasomal activity
    • Malhotra, D. et al. Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: The role of Nrf2-regulated proteasomal activity. Am. J. Respir. Crit. Care Med. 180, 1196-1207 (2009).
    • (2009) Am. J. Respir. Crit. Care Med. , vol.180 , pp. 1196-1207
    • Malhotra, D.1
  • 109
    • 84863523330 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in chronic obstructive lung diseases
    • Ribeiro, C.M.P. & O+Neal, W.K. Endoplasmic reticulum stress in chronic obstructive lung diseases. Curr. Mol. Med. 12, 872-882 (2012).
    • (2012) Curr. Mol. Med. , vol.12 , pp. 872-882
    • Ribeiro, C.M.P.1    Oneal, W.K.2
  • 110
    • 42949118737 scopus 로고    scopus 로고
    • Cigarette smoke induces an unfolded protein response in the human lung: A proteomic approach
    • Kelsen, S.G. et al. Cigarette smoke induces an unfolded protein response in the human lung: A proteomic approach. Am. J. Respir. Cell Mol. Biol. 38, 541-550 (2008).
    • (2008) Am. J. Respir. Cell Mol. Biol. , vol.38 , pp. 541-550
    • Kelsen, S.G.1
  • 111
    • 79953068336 scopus 로고    scopus 로고
    • Emerging role of damage-associated molecular patterns derived frommitochondria in inflammation
    • Krysko, D.V. et al. Emerging role of damage-associated molecular patterns derived frommitochondria in inflammation. Trends Immunol. 32, 157-164 (2011).
    • (2011) Trends Immunol. , vol.32 , pp. 157-164
    • Krysko, D.V.1
  • 112
    • 84895132462 scopus 로고    scopus 로고
    • Mitochondrial damage-associated molecular patterns activate gd T-cells
    • e-pub ahead of print
    • Schwacha, M.G., Rani, M., Zhang, Q., Nunez-Cantu, O. & Cap, A.P. Mitochondrial damage-associated molecular patterns activate gd T-cells. Innate Immun. (2013; e-pub ahead of print).
    • (2013) Innate Immun.
    • Schwacha, M.G.1    Rani, M.2    Zhang, Q.3    Nunez-Cantu, O.4    Cap, A.P.5
  • 113
    • 84875138335 scopus 로고    scopus 로고
    • Mitochondrial DAMPs increase endothelial permeability through neutrophil dependent and independent pathways
    • Sun, S. et al. Mitochondrial DAMPs increase endothelial permeability through neutrophil dependent and independent pathways. PLoS One 8, e59989 (2013).
    • (2013) PLoS One , vol.8
    • Sun, S.1
  • 115
    • 2642573579 scopus 로고    scopus 로고
    • Endogenously oxidized mitochondrial DNA induces in vivo and in vitro inflammatory responses
    • Collins, L.V. et al. Endogenously oxidized mitochondrial DNA induces in vivo and in vitro inflammatory responses. J. Leukoc. Biol. 75, 995-1000 (2004).
    • (2004) J. Leukoc. Biol. , vol.75 , pp. 995-1000
    • Collins, L.V.1
  • 116
    • 0033980073 scopus 로고    scopus 로고
    • The role of CpG motifs in innate immunity
    • Krieg, A.M. The role of CpG motifs in innate immunity. Curr. Opin. Immunol. 12, 35-43 (2000).
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 35-43
    • Krieg, A.M.1
  • 117
    • 77950275298 scopus 로고    scopus 로고
    • Circulating mitochondrial DAMPs cause inflammatory responses to injury
    • Zhang, Q. et al. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature 464, 104-107 (2010).
    • (2010) Nature , vol.464 , pp. 104-107
    • Zhang, Q.1
  • 118
    • 0016795577 scopus 로고
    • The isolation and partial characterization of neutrophil chemotactic factors from Escherichia coli
    • Schiffmann, E. et al. The isolation and partial characterization of neutrophil chemotactic factors from Escherichia coli. J. Immunol. 114, 1831-1837 (1975).
    • (1975) J. Immunol. , vol.114 , pp. 1831-1837
    • Schiffmann, E.1
  • 119
    • 0001733810 scopus 로고
    • N-formylmethionyl peptides as chemoattractants for leucocytes
    • Schiffmann, E., Corcoran, B.A. &Wahl, S.M. N-formylmethionyl peptides as chemoattractants for leucocytes. Proc. Natl. Acad. Sci. USA 72, 1059-1062 (1975).
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , pp. 1059-1062
    • Schiffmann, E.1    Corcoran, B.A.2    Wahl, S.M.3
  • 120
    • 0020062002 scopus 로고
    • Mitochondrial N-formylmethionyl proteins as chemoattractants for neutrophils
    • Carp, H. Mitochondrial N-formylmethionyl proteins as chemoattractants for neutrophils. J. Exp. Med. 155, 264-275 (1982).
    • (1982) J. Exp. Med. , vol.155 , pp. 264-275
    • Carp, H.1
  • 121
    • 33751211223 scopus 로고    scopus 로고
    • Formyl peptide receptors: A promiscuous subfamily of G protein-coupled receptors controlling immune responses
    • Migeotte, I., Communi, D. & Parmentier, M. Formyl peptide receptors: A promiscuous subfamily of G protein-coupled receptors controlling immune responses. Cytokine Growth Factor Rev. 17, 501-519 (2006).
    • (2006) Cytokine Growth Factor Rev. , vol.17 , pp. 501-519
    • Migeotte, I.1    Communi, D.2    Parmentier, M.3
  • 122
    • 0025615835 scopus 로고
    • The human N-formylpeptide receptor.Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors
    • Boulay, F., Tardif, M., Brouchon, L. & Vignais, P. The human N-formylpeptide receptor.Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors. Biochemistry 29, 11123-11133 (1990).
    • (1990) Biochemistry , vol.29 , pp. 11123-11133
    • Boulay, F.1    Tardif, M.2    Brouchon, L.3    Vignais, P.4
  • 123
    • 77953788926 scopus 로고    scopus 로고
    • Mitochondrial peptides are potent immune activators that activate human neutrophils via FPR-1
    • discussion 1332-4
    • Raoof, M., Zhang, Q., Itagaki, K. & Hauser, C.J. Mitochondrial peptides are potent immune activators that activate human neutrophils via FPR-1. J. Trauma 68, 1328-1332. discussion 1332-4 (2010).
    • (2010) J. Trauma , vol.68 , pp. 1328-1332
    • Raoof, M.1    Zhang, Q.2    Itagaki, K.3    Hauser, C.J.4
  • 124
    • 77957943307 scopus 로고    scopus 로고
    • Intravascular danger signals guide neutrophils to sites of sterile inflammation
    • McDonald, B. et al. Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science 330, 362-366 (2010).
    • (2010) Science , vol.330 , pp. 362-366
    • McDonald, B.1
  • 125
    • 70949086145 scopus 로고    scopus 로고
    • Absence of proteinase-activated receptor-1 signaling in mice confers protection from fMLP-induced goblet cell metaplasia
    • Atzori, L. et al. Absence of proteinase-activated receptor-1 signaling in mice confers protection from fMLP-induced goblet cell metaplasia. Am. J. Respir. Cell Mol. Biol. 41, 680-687 (2009).
    • (2009) Am. J. Respir. Cell Mol. Biol. , vol.41 , pp. 680-687
    • Atzori, L.1
  • 126
    • 84865827606 scopus 로고    scopus 로고
    • Genetic ablation of the fpr1 gene confers protection from smoking-induced lung emphysema in mice
    • Cardini, S. et al. Genetic ablation of the fpr1 gene confers protection from smoking-induced lung emphysema in mice. Am. J. Respir. Cell Mol. Biol. 47, 332-339 (2012).
    • (2012) Am. J. Respir. Cell Mol. Biol. , vol.47 , pp. 332-339
    • Cardini, S.1
  • 127
    • 0038555334 scopus 로고    scopus 로고
    • Cigarette smoking increases neutrophil formyl methionyl leucyl phenylalanine receptor numbers
    • Matheson, M., Rynell, A.-C., McClean, M. & Berend, N. Cigarette smoking increases neutrophil formyl methionyl leucyl phenylalanine receptor numbers. Chest 123, 1642-1646 (2003).
    • (2003) Chest , vol.123 , pp. 1642-1646
    • Matheson, M.1    Rynell, A.-C.2    McClean, M.3    Berend, N.4
  • 128
    • 70350569295 scopus 로고    scopus 로고
    • Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
    • Ghiringhelli, F. et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat. Med. 15, 1170-1178 (2009).
    • (2009) Nat. Med. , vol.15 , pp. 1170-1178
    • Ghiringhelli, F.1
  • 130
    • 33845708770 scopus 로고    scopus 로고
    • ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors
    • Chen, Y. et al. ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science 314, 1792-1795 (2006).
    • (2006) Science , vol.314 , pp. 1792-1795
    • Chen, Y.1
  • 131
    • 77952305210 scopus 로고    scopus 로고
    • Extracellular adenosine triphosphate and chronic obstructive pulmonary disease
    • Lommatzsch, M. et al. Extracellular adenosine triphosphate and chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 181, 928-934 (2010).
    • (2010) Am. J. Respir. Crit. Care Med. , vol.181 , pp. 928-934
    • Lommatzsch, M.1
  • 132
    • 0031201476 scopus 로고    scopus 로고
    • Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages
    • Ferrari, D. et al. Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages. J. Immunol. 159, 1451-1458 (1997).
    • (1997) J. Immunol. , vol.159 , pp. 1451-1458
    • Ferrari, D.1
  • 133
    • 69749111918 scopus 로고    scopus 로고
    • ATP in the pathogenesis of lung emphysema
    • Mortaz, E. et al. ATP in the pathogenesis of lung emphysema. Eur. J. Pharmacol. 619, 92-96 (2009).
    • (2009) Eur. J. Pharmacol. , vol.619 , pp. 92-96
    • Mortaz, E.1
  • 134
    • 79952218099 scopus 로고    scopus 로고
    • P2-7 receptor signaling in the pathogenesis of smoke-induced lung inflammation and emphysema
    • Lucattelli, M. et al. P2-7 receptor signaling in the pathogenesis of smoke-induced lung inflammation and emphysema. Am. J. Respir. Cell Mol. Biol. 44, 423-429 (2011).
    • (2011) Am. J. Respir. Cell Mol. Biol. , vol.44 , pp. 423-429
    • Lucattelli, M.1
  • 135
    • 77956194973 scopus 로고    scopus 로고
    • Purinergic receptor inhibition prevents the development of smoke-induced lung injury and emphysema
    • Cicko, S. et al. Purinergic receptor inhibition prevents the development of smoke-induced lung injury and emphysema. J. Immunol. 185, 688-697 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 688-697
    • Cicko, S.1
  • 136
    • 1842740658 scopus 로고    scopus 로고
    • Cardiolipin and its metabolites move frommitochondria to other cellular membranes during death receptor-mediated apoptosis
    • Sorice,M. et al. Cardiolipin and its metabolites move frommitochondria to other cellular membranes during death receptor-mediated apoptosis. Cell Death Differ. 11, 1133-1145 (2004).
    • (2004) Cell Death Differ. , vol.11 , pp. 1133-1145
    • Sorice, M.1
  • 137
    • 0026609177 scopus 로고
    • Role of surfactant in chronic obstructive pulmonary disease: Therapeutic implications
    • Lusuardi, M. et al. Role of surfactant in chronic obstructive pulmonary disease: Therapeutic implications. Respiration 59 (Suppl 1), 28-32 (1992).
    • (1992) Respiration , vol.59 , Issue.SUPPL. 1 , pp. 28-32
    • Lusuardi, M.1
  • 138
    • 84887086485 scopus 로고    scopus 로고
    • Damageassociated molecular patterns and their receptors in upper airway pathologies
    • e-pub ahead of print
    • Van Crombruggen, K., Jacob, F., Zhang, N. & Bachert, C. Damageassociated molecular patterns and their receptors in upper airway pathologies. Cell. Mol. Life Sci. (2013; e-pub ahead of print).
    • (2013) Cell. Mol. Life Sci.
    • Van Crombruggen, K.1    Jacob, F.2    Zhang, N.3    Bachert, C.4
  • 139
    • 77956672918 scopus 로고    scopus 로고
    • Altered fibroblast proteoglycan production in COPD
    • Hallgren, O. et al. Altered fibroblast proteoglycan production in COPD. Respir. Res. 11, 55 (2010).
    • (2010) Respir. Res. , vol.11 , pp. 55
    • Hallgren, O.1
  • 140
    • 46249083873 scopus 로고    scopus 로고
    • Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease
    • Merrilees, M.J. et al. Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease. Respir. Res. 9, 41 (2008).
    • (2008) Respir. Res. , vol.9 , pp. 41
    • Merrilees, M.J.1
  • 141
    • 84871228207 scopus 로고    scopus 로고
    • Extracellular matrix composition in chronic obstructive pulmonary disease
    • Annoni, R. et al. Extracellular matrix composition in chronic obstructive pulmonary disease. Eur. Respir. J. 40, 1362-1373 (2012).
    • (2012) Eur. Respir. J. , vol.40 , pp. 1362-1373
    • Annoni, R.1
  • 143
    • 33750717856 scopus 로고    scopus 로고
    • Enhanced bronchial expression of extracellular matrix proteins in chronic obstructive pulmonary disease
    • Kranenburg, A.R. et al. Enhanced bronchial expression of extracellular matrix proteins in chronic obstructive pulmonary disease. Am. J. Clin. Pathol. 126, 725-735 (2006).
    • (2006) Am. J. Clin. Pathol. , vol.126 , pp. 725-735
    • Kranenburg, A.R.1
  • 144
    • 77953254345 scopus 로고    scopus 로고
    • Enhanced deposition of low-molecular-weight hyaluronan in lungs of cigarette smoke-exposed mice
    • Bracke, K.R. et al. Enhanced deposition of low-molecular-weight hyaluronan in lungs of cigarette smoke-exposed mice. Am. J. Respir. Cell Mol. Biol. 42, 753-761 (2010).
    • (2010) Am. J. Respir. Cell Mol. Biol. , vol.42 , pp. 753-761
    • Bracke, K.R.1
  • 145
    • 13544251372 scopus 로고    scopus 로고
    • Enhanced levels of hyaluronan in lungs of patients with COPD: Relationship with lung function and local inflammation
    • Dentener, M.A., Vernooy, J.H.J., Hendriks, S. & Wouters, E.F.M. Enhanced levels of hyaluronan in lungs of patients with COPD: Relationship with lung function and local inflammation. Thorax 60, 114-119 (2005).
    • (2005) Thorax , vol.60 , pp. 114-119
    • Dentener, M.A.1    Vernooy, J.H.J.2    Hendriks, S.3    Wouters, E.F.M.4
  • 146
    • 80051481307 scopus 로고    scopus 로고
    • RIP1-dependent and independent effects of necrostatin-1 in necrosis and Tcell activation
    • Cho, Y., McQuade, T., Zhang, H., Zhang, J. & Chan, F.K.-M. RIP1-dependent and independent effects of necrostatin-1 in necrosis and Tcell activation. PLoS One 6, e23209 (2011).
    • (2011) PLoS One , vol.6
    • Cho, Y.1    McQuade, T.2    Zhang, H.3    Zhang, J.4    Chan, F.K.-M.5
  • 147
    • 40449118020 scopus 로고    scopus 로고
    • Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent
    • Doz, E. et al. Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent. J. Immunol. 180, 1169-1178 (2008).
    • (2008) J. Immunol. , vol.180 , pp. 1169-1178
    • Doz, E.1
  • 148
    • 44449112349 scopus 로고    scopus 로고
    • Comment on +Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent+
    • Maes, T., Bracke, K.R., Joos, G.F. & Brusselle, G.G. Comment on +Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent+. J. Immunol. 180, 5761 (2008).
    • (2008) J. Immunol. , vol.180 , pp. 5761
    • Maes, T.1    Bracke, K.R.2    Joos, G.F.3    Brusselle, G.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.