Apoptosis and necrosis: Two different outcomes of cigarette smoke condensate-induced endothelial cell death

Cell Death and Disease

Volumn 3, Issue 11, 2012, Pages

  Messner, B ^a   Frotschnig, S ^b   Steinacher Nigisch, A ^a   Winter, B ^a   Eichmair, E ^a   Gebetsberger, J ^b   Schwaiger, S ^c   Ploner, C ^b   Laufer, G ^a   Bernhard, D ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Apoptosis; Atherosclerosis; BCL XL; Cigarette smoke condensate; Necrosis; P53

Indexed keywords

APOPTOSIS INDUCING FACTOR; CIGARETTE SMOKE CONDENSATE; PROTEIN BCL XL; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; WESTERN BLOTTING;

APOPTOSIS INDUCING FACTOR; CELL DEATH; CELLS, CULTURED; DNA DAMAGE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; NECROSIS; REACTIVE OXYGEN SPECIES; SMOKING; TOBACCO;

EID: 84870564051     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.162     Document Type: Article

References (60)

1. Mallat Z, Tedgui A. Apoptosis in the vasculature: mechanisms and functional importance. Br J Pharmacol 2000; 130: 947-962.
2. Organisation WH Tobacco - Fact Sheet No 339. World Health Organisation, 2012.
3. Knoflach M, Kiechl S, Kind M, Said M, Sief R, Gisinger M et al. Cardiovascular risk factors and atherosclerosis in young males: ARMY study (atherosclerosis risk-factors in male youngsters). Circulation 2003; 108: 1064-1069.
4. Powell JT. Vascular damage from smoking: disease mechanisms at the arterial wall. Vasc Med 1998; 3: 21-28.
5. Ambrose JA, Barua RS. The pathophysiology of cigarette smoking and cardiovascular disease: an update. J Am Coll Cardiol 2004; 43: 1731-1737.
6. Pryor WA, Stone K. Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite. Ann NY Acad Sci 1993; 686: 12-27; discussion 27-28.
7. Mannarino E, Pirro M. Molecular biology of atherosclerosis. Clin Cases Miner Bone Metab 2008; 5: 57-62.
8. Zheng Y, Gardner SE, Clarke MC. Cell death, damage-associated molecular patterns, and sterile inflammation in cardiovascular disease. Arterioscler Thromb Vasc Biol 2011; 31: 2781-2786.
9. Edinger AL, Thompson CB. Death by design: apoptosis, necrosis and autophagy. Curr Opin Cell Biol 2004; 16: 663-669.
10. Kanduc D, Mittelman A, Serpico R, Sinigaglia E, Sinha AA, Natale C et al. Cell death: apoptosis versus necrosis (review). Int J Oncol 2002; 21: 165-170.
11. Duprez L, Wirawan E, Vanden Berghe T, Vandenabeele P. Major cell death pathways at a glance. Microbes Infect 2009; 11: 1050-1062.
12. Elmore S. Apoptosis: a review of programmed cell death. Toxicol Pathol 2007; 35: 495-516.
13. Strasser A, O'Connor L, Dixit VM. Apoptosis signaling. Annu Rev Biochem 2000; 69: 217-245.
14. Vogelstein B, Lane D, Levine AJ. Surfing the p53 network. Nature 2000; 408: 307-310.
15. Haupt S, Berger M, Goldberg Z, Haupt Y. Apoptosis - the p53 network. J Cell Sci 2003; 116(Part 20): 4077-4085.
16. Chipuk JE, Green DR. Dissecting p53-dependent apoptosis. Cell Death Differ 2006; 13: 994-1002.
17. van Loo G, Saelens X, van Gurp M, MacFarlane M, Martin SJ, Vandenabeele P. The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet. Cell Death Differ 2002; 9: 1031-1042.
18. Larsen CJ. [The BCL2 gene, prototype of a gene family that controls programmed cell death (apoptosis)]. Ann Genet 1994; 37: 121-134.
19. Green DR, Reed JC. Mitochondria and apoptosis. Science 1998; 281: 1309-1312.
20. Crawford ED, Wells JA. Caspase substrates and cellular remodeling. Annu Rev Biochem 2011; 80: 1055-1087.
21. Shi Y. Mechanisms of caspase activation and inhibition during apoptosis. Mol Cell 2002; 9: 459-470.
22. Cande C, Cecconi F, Dessen P, Kroemer G. Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death? J Cell Sci 2002; 115(Part 24): 4727-4734.
23. Lorenzo HK, Susin SA, Penninger J, Kroemer G. Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death. Cell Death Differ 1999; 6: 516-524.
24. Zong WX, Ditsworth D, Bauer DE, Wang ZQ, Thompson CB. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 2004; 18: 1272-1282.
25. Mizushima N, Ohsumi Y, Yoshimori T. Autophagosome formation in mammalian cells. Cell Struct Funct 2002; 27: 421-429.
26. He C, Klionsky DJ. Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet 2009; 43: 67-93.
27. Bernhard D, Csordas A, Henderson B, Rossmann A, Kind M, Wick G. Cigarette smoke metal-catalyzed protein oxidation leads to vascular endothelial cell contraction by depolymerization of microtubules. FASEB J 2005; 19: 1096-1107.
28. Henderson B, Csordas A, Backovic A, Kind M, Bernhard D, Wick G. Cigarette smoke is an endothelial stressor and leads to cell cycle arrest. Atherosclerosis 2008; 201: 298-305.
29. Edirisinghe I, Arunachalam G, Wong C, Yao H, Rahman A, Phipps RP et al. Cigarette-smoke-induced oxidative/nitrosative stress impairs VEGF- and fluidshear- stress-mediated signaling in endothelial cells. Antioxid Redox Signal 2010; 12: 1355-1369.
30. Chen HW, Lii CK, Ku HJ, Wang TS. Cigarette smoke extract induces expression of cell adhesion molecules in HUVEC via actin filament reorganization. Environ Mol Mutagen 2009; 50: 96-104.
31. Messner B, Knoflach M, Seubert A, Ritsch A, Pfaller K, Henderson B et al. Cadmium is a novel and independent risk factor for early atherosclerosis mechanisms and in vivo relevance. Arterioscler Thromb Vasc Biol 2009; 29: 1392-1398.
32. Guarino F, Cantarella G, Caruso M, Russo C, Mancuso S, Arcidiacono G et al. Endothelial activation and injury by cigarette smoke exposure. J Biol Regul Homeost Agents 2011; 25: 259-268.
33. Csordas A, Kreutmayer S, Ploner C, Braun PR, Karlas A, Backovic A et al. Cigarette smoke extract induces prolonged endoplasmic reticulum stress and autophagic cell death in human umbilical vein endothelial cells. Cardiovasc Res 2011; 92: 141-148.
34. Penn A, Keller K, Snyder C, Nadas A, Chen LC. The tar fraction of cigarette smoke does not promote arteriosclerotic plaque development. Environ Health Perspect 1996; 104: 1108-1113.
35. Jianlin L, Guohai C, Guojun Z, Jian J, Fangfang H, Juanjuan X et al. Assessing cytogenotoxicity of cigarette smoke condensates using three in vitro assays. Mutat Res 2009; 677: 21-26.
36. Nordskog BK, Fields WR, Hellmann GM. Kinetic analysis of cytokine response to cigarette smoke condensate by human endothelial and monocytic cells. Toxicology 2005; 212: 87-97.
37. Nordskog BK, Blixt AD, Morgan WT, Fields WR, Hellmann GM. Matrix-degrading and proinflammatory changes in human vascular endothelial cells exposed to cigarette smoke condensate. Cardiovasc Toxicol 2003; 3: 101-117.
38. Kalra VK, Ying Y, Deemer K, Natarajan R, Nadler JL, Coates TD. Mechanism of cigarette smoke condensate induced adhesion of human monocytes to cultured endothelial cells. J Cell Physiol 1994; 160: 154-162.
39. Shen Y, Rattan V, Sultana C, Kalra VK. Cigarette smoke condensate-induced adhesion molecule expression and transendothelial migration of monocytes. Am J Physiol 1996; 270(5 Part 2): H1624-H1633.
40. Snajdar RM, Busuttil SJ, Averbook A, Graham DJ. Inhibition of endothelial cell migration by cigarette smoke condensate. J Surg Res 2001; 96: 10-16.
41. Csordas A, Wick G, Bernhard D. Hydrogen peroxide-mediated necrosis induction in HUVECs is associated with an atypical pattern of caspase-3 cleavage. Exp Cell Res 2006; 312: 1753-1764.
42. DeMarini DM. Genotoxicity of tobacco smoke and tobacco smoke condensate: a review. Mutat Res 2004; 567: 447-474.
43. Eguchi Y, Shimizu S, Tsujimoto Y. Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res 1997; 57: 1835-1840.
44. Porter AG, Janicke RU. Emerging roles of caspase-3 in apoptosis. Cell Death Differ 1999; 6: 99-104.
45. Hampton MB, Orrenius S. Redox regulation of apoptotic cell death in the immune system. Toxicol Lett 1998; 102-103: 355-358.
46. Riedl SJ, Salvesen GS. The apoptosome: signalling platform of cell death. Nat Rev Mol Cell Biol 2007; 8: 405-413.
47. Daugas E, Susin SA, Zamzami N, Ferri KF, Irinopoulou T, Larochette N et al. Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. FASEB J 2000; 14: 729-739.
48. Joza N, Susin SA, Daugas E, Stanford WL, Cho SK, Li CY et al. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 2001; 410: 549-554.
49. Turk B, Turk V. Lysosomes as 'suicide bags' in cell death: myth or reality? J Biol Chem 2009; 284: 21783-21787.
50. Guicciardi ME, Leist M, Gores GJ. Lysosomes in cell death. Oncogene 2004; 23: 2881-2890.
51. Pratt MM, John K, MacLean AB, Afework S, Phillips DH, Poirier MC. Polycyclic aromatic hydrocarbon (PAH) exposure and DNA adduct semi-quantitation in archived human tissues. Int J Environ Res Public Health 2011; 8: 2675-2691.
52. Calafat AM, Polzin GM, Saylor J, Richter P, Ashley DL, Watson CH. Determination of tar, nicotine, and carbon monoxide yields in the mainstream smoke of selected international cigarettes. Tob Control 2004; 13: 45-51.
53. Amberger A, Maczek C, Jurgens G, Michaelis D, Schett G, Trieb K et al. Co-expression of ICAM-1, VCAM-1, ELAM-1 and Hsp60 in human arterial and venous endothelial cells in response to cytokines and oxidized low-density lipoproteins. Cell Stress Chaperones 1997; 2: 94-103.
54. Bernhard D, Huck CW, Jakschitz T, Pfister G, Henderson B, Bonn GK et al. Development and evaluation of an in vitro model for the analysis of cigarette smoke effects on cultured cells and tissues. J Pharmacol Toxicol Methods 2004; 50: 45-51.
55. Sigl R, Wandke C, Rauch V, Kirk J, Hunt T, Geley S. Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis. J Cell Sci 2009; 122(Part 22): 4208-4217.
56. Kutner RH, Zhang XY, Reiser J. Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors. Nat Protoc 2009; 4: 495-505.
57. Ploner C, Rainer J, Niederegger H, Eduardoff M, Villunger A, Geley S et al. The BCL2 rheostat in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia. Leukemia 2008; 22: 370-377.
58. Bernhard D, Pfister G, Huck CW, Kind M, Salvenmoser W, Bonn GK et al. Disruption of vascular endothelial homeostasis by tobacco smoke: impact on atherosclerosis. FASEB J 2003; 17: 2302-2304.
59. Bernhard D, Skvortsov S, Tinhofer I, Hubl H, Greil R, Csordas A et al. Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts. Cell Death Differ 2001; 8: 1014-1021.
60. Messner B, Zeller I, Ploner C, Frotschnig S, Ringer T, Steinacher-Nigisch A et al. Ursolic acid causes DNA-damage, p53-mediated, mitochondria- and caspase-dependent human endothelial cell apoptosis, and accelerates atherosclerotic plaque formation in vivo. Atherosclerosis 2011; 219: 402-408.