-
1
-
-
0033542413
-
Emergence of vancomycin tolerance in Streptococcus pneumoniae
-
Novak R, Henriques B, Charpentier E, Normark S, Tuomanen E (1999) Emergence of vancomycin tolerance in Streptococcus pneumoniae. Nature 399:590-593
-
(1999)
Nature
, vol.399
, pp. 590-593
-
-
Novak, R.1
Henriques, B.2
Charpentier, E.3
Normark, S.4
Tuomanen, E.5
-
2
-
-
0035691095
-
Antibiotic resistance: Prospects for the new millennium
-
Daw, MA, Drah AM (2001) Antibiotic resistance: prospects for the new millennium. J Chemother 13:587-594
-
(2001)
J Chemother
, vol.13
, pp. 587-594
-
-
Daw, M.A.1
Drah, A.M.2
-
3
-
-
0029347190
-
Plant defensins: Novel antimicrobial peptides as components of the host defense system
-
Broekaert WF, Terras FR, Cammue BP, Osborn RW (1995) Plant defensins: novel antimicrobial peptides as components of the host defense system. Plant Physiol 108:1353-1358
-
(1995)
Plant Physiol
, vol.108
, pp. 1353-1358
-
-
Broekaert, W.F.1
Terras, F.R.2
Cammue, B.P.3
Osborn, R.W.4
-
4
-
-
0020366780
-
Insect immunity: Isolation and structure of cecropin D and four minor antibacterial components from Cecropia pupae
-
Hultmark D, Engstrom A, Bennich H, Kapur R, Boman HG (1982) Insect immunity: isolation and structure of cecropin D and four minor antibacterial components from Cecropia pupae. Eur J Biochem 127:207-217
-
(1982)
Eur J Biochem
, vol.127
, pp. 207-217
-
-
Hultmark, D.1
Engstrom, A.2
Bennich, H.3
Kapur, R.4
Boman, H.G.5
-
5
-
-
0033067196
-
Antimicrobial peptides in mammalian and insect host defence
-
Lehrer RI, Ganz T (1999) Antimicrobial peptides in mammalian and insect host defence. Curr Opin Immunol 11:23-27
-
(1999)
Curr Opin Immunol
, vol.11
, pp. 23-27
-
-
Lehrer, R.I.1
Ganz, T.2
-
6
-
-
0031821708
-
Gene-encoded peptide antibiotics and the concept of innate immunity: An update review
-
Boman HG (1998) Gene-encoded peptide antibiotics and the concept of innate immunity: an update review. Scand J Immunol 48:15-25
-
(1998)
Scand J Immunol
, vol.48
, pp. 15-25
-
-
Boman, H.G.1
-
7
-
-
0031574103
-
The cathelicidin family of antimicrobial peptide precursors: A component of the oxygen-independent defense mechanisms of neutrophils
-
Zanetti M, Gennaro R, Romeo D (1997) The cathelicidin family of antimicrobial peptide precursors: a component of the oxygen-independent defense mechanisms of neutrophils. Ann N Y Acad Sci 832:147-162
-
(1997)
Ann N Y Acad Sci
, vol.832
, pp. 147-162
-
-
Zanetti, M.1
Gennaro, R.2
Romeo, D.3
-
8
-
-
0032005344
-
Antimicrobial peptides of vertebrates
-
Ganz T, Lehrer RI (1998) Antimicrobial peptides of vertebrates. Curr Opin Immunol 10:41-44
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 41-44
-
-
Ganz, T.1
Lehrer, R.I.2
-
9
-
-
0033962266
-
Innate immunity and the normal microflora
-
Boman HG (2000) Innate immunity and the normal microflora. Immunol Rev 173:5-16
-
(2000)
Immunol Rev
, vol.173
, pp. 5-16
-
-
Boman, H.G.1
-
10
-
-
0033863168
-
Structural features and biological activities of the cathelicidin-derived antimicrobial peptides
-
Gennaro R, Zanetti M (2000) Structural features and biological activities of the cathelicidin-derived antimicrobial peptides. Biopolymers 55:31-49
-
(2000)
Biopolymers
, vol.55
, pp. 31-49
-
-
Gennaro, R.1
Zanetti, M.2
-
11
-
-
0033569682
-
Defensins and host defense
-
Ganz T (1999) Defensins and host defense. Science 286:420-421
-
(1999)
Science
, vol.286
, pp. 420-421
-
-
Ganz, T.1
-
12
-
-
0032717048
-
Diversity of antimicrobial peptides and their mechanisms of action
-
Epand RM, Vogel HJ (1999) Diversity of antimicrobial peptides and their mechanisms of action. Biochim Biophys Acta 1462:11-28
-
(1999)
Biochim Biophys Acta
, vol.1462
, pp. 11-28
-
-
Epand, R.M.1
Vogel, H.J.2
-
13
-
-
0034952982
-
Defensins - Innate immunity at the epithelial frontier
-
Fellermann K, Stange EF (2001) Defensins - innate immunity at the epithelial frontier. Eur J Gastroenterol Hepatol 13:771-776
-
(2001)
Eur J Gastroenterol Hepatol
, vol.13
, pp. 771-776
-
-
Fellermann, K.1
Stange, E.F.2
-
14
-
-
0037005996
-
Current status of defensins and their role in innate and adaptive immunity
-
Raj PA, Dentino AR (2002) Current status of defensins and their role in innate and adaptive immunity. FEMS Microbiol Lett 206:9-18
-
(2002)
FEMS Microbiol Lett
, vol.206
, pp. 9-18
-
-
Raj, P.A.1
Dentino, A.R.2
-
15
-
-
0028844134
-
Cathelicidins: A novel protein family with a common proregion and a variable C-terminal antimicrobial domain
-
Zanetti M, Gennaro R, Romeo D (1995) Cathelicidins: a novel protein family with a common proregion and a variable C-terminal antimicrobial domain. FEBS Lett 374:1-5
-
(1995)
FEBS Lett
, vol.374
, pp. 1-5
-
-
Zanetti, M.1
Gennaro, R.2
Romeo, D.3
-
17
-
-
0024349857
-
Primary structure of a new cysteine proteinase inhibitor from pig leucocytes
-
Ritonja A, Kopitar M, Jerala R, Turk V (1989) Primary structure of a new cysteine proteinase inhibitor from pig leucocytes. FEBS Lett 255:211-214
-
(1989)
FEBS Lett
, vol.255
, pp. 211-214
-
-
Ritonja, A.1
Kopitar, M.2
Jerala, R.3
Turk, V.4
-
18
-
-
0025990384
-
Complementary DNA sequence of rabbit CAP18-a unique lipopolysaccharide binding protein
-
Larrick JW, Morgan JG, Palings I, Hirata M, Yen MH (1991) Complementary DNA sequence of rabbit CAP18-a unique lipopolysaccharide binding protein. Biochem Biophys Res Commun 179:170-175
-
(1991)
Biochem Biophys Res Commun
, vol.179
, pp. 170-175
-
-
Larrick, J.W.1
Morgan, J.G.2
Palings, I.3
Hirata, M.4
Yen, M.H.5
-
19
-
-
0028009472
-
Chemical synthesis and biological activity of a novel antibacterial peptide deduced from a pig myeloid cDNA
-
Storici P, Scocchi M, Tossi A, Gennaro R, Zanetti M (1994) Chemical synthesis and biological activity of a novel antibacterial peptide deduced from a pig myeloid cDNA. FEBS Lett 337:303-307
-
(1994)
FEBS Lett
, vol.337
, pp. 303-307
-
-
Storici, P.1
Scocchi, M.2
Tossi, A.3
Gennaro, R.4
Zanetti, M.5
-
20
-
-
0028904007
-
PMAP-37, a novel antibacterial peptide from pig myeloid cells. cDNA cloning, chemical synthesis and activity
-
Tossi A, Scocchi M, Zanetti M, Storici P, Gennaro R (1995) PMAP-37, a novel antibacterial peptide from pig myeloid cells. cDNA cloning, chemical synthesis and activity. Eur J Biochem 228:941-946
-
(1995)
Eur J Biochem
, vol.228
, pp. 941-946
-
-
Tossi, A.1
Scocchi, M.2
Zanetti, M.3
Storici, P.4
Gennaro, R.5
-
21
-
-
0027472180
-
The cDNA of the neutrophil antibiotic Bac5 predicts a pro-sequence homologous to a cysteine proteinase inhibitor that is common to other neutrophil antibiotics
-
Zanetti M, Del Sal G, Storici P, Schneider C, Romeo D (1993) The cDNA of the neutrophil antibiotic Bac5 predicts a pro-sequence homologous to a cysteine proteinase inhibitor that is common to other neutrophil antibiotics. J Biol Chem 268: 522-526
-
(1993)
J Biol Chem
, vol.268
, pp. 522-526
-
-
Zanetti, M.1
Del Sal, G.2
Storici, P.3
Schneider, C.4
Romeo, D.5
-
22
-
-
0028834275
-
cDNA sequences of three sheep myeloid cathelicidins
-
Bagella L, Scocchi M, Zanetti M (1995) cDNA sequences of three sheep myeloid cathelicidins. FEBS Lett 376:225-228
-
(1995)
FEBS Lett
, vol.376
, pp. 225-228
-
-
Bagella, L.1
Scocchi, M.2
Zanetti, M.3
-
23
-
-
0032878239
-
Novel cathelicidins in horse leukocytes (1)
-
Scocchi M, Bontempo D, Boscolo S, Tomasinsig L, Giulotto E, Zanetti M (1999) Novel cathelicidins in horse leukocytes (1). FEBS Lett 457:459-464
-
(1999)
FEBS Lett
, vol.457
, pp. 459-464
-
-
Scocchi, M.1
Bontempo, D.2
Boscolo, S.3
Tomasinsig, L.4
Giulotto, E.5
Zanetti, M.6
-
24
-
-
0031009432
-
Identification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse
-
Gallo RL, Kim KJ, Bernfield, M, Kozak CA, Zanetti M, Merluzzi L, Gennaro R (1997) Identification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse. J Biol Chem 272:13088-13093
-
(1997)
J Biol Chem
, vol.272
, pp. 13088-13093
-
-
Gallo, R.L.1
Kim, K.J.2
Bernfield, M.3
Kozak, C.A.4
Zanetti, M.5
Merluzzi, L.6
Gennaro, R.7
-
25
-
-
0028942078
-
FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis
-
Agerberth B, Gunne H, Odeberg J, Kogner P, Boman HG, Gudmundsson GH (1995) FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis. Proc Natl Acad Sci U S A 92:195-199
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 195-199
-
-
Agerberth, B.1
Gunne, H.2
Odeberg, J.3
Kogner, P.4
Boman, H.G.5
Gudmundsson, G.H.6
-
26
-
-
0032808386
-
Purification and properties of proline-rich antimicrobial peptides from sheep and goat leukocytes
-
Shamova O, Brogden KA, Zhao C, Nguyen T, Kokryakov VN, Lehrer RI (1999) Purification and properties of proline-rich antimicrobial peptides from sheep and goat leukocytes. Infect Immun 67:4106-4111
-
(1999)
Infect Immun
, vol.67
, pp. 4106-4111
-
-
Shamova, O.1
Brogden, K.A.2
Zhao, C.3
Nguyen, T.4
Kokryakov, V.N.5
Lehrer, R.I.6
-
27
-
-
0034098916
-
Bactericidal activity of mammalian cathelicidin-derived peptides
-
Travis SM, Anderson NN, Forsyth WR, Espiritu C, Conway BD, Greenberg EP, McCray PB Jr, Lehrer RI, Welsh MJ, Tack BF (2000) Bactericidal activity of mammalian cathelicidin-derived peptides. Infect Immun 68:2748-2755
-
(2000)
Infect Immun
, vol.68
, pp. 2748-2755
-
-
Travis, S.M.1
Anderson, N.N.2
Forsyth, W.R.3
Espiritu, C.4
Conway, B.D.5
Greenberg, E.P.6
McCray P.B., Jr.7
Lehrer, R.I.8
Welsh, M.J.9
Tack, B.F.10
-
28
-
-
0030961007
-
Isolation of cDNA encoding guinea pig neutrophil cationic antibacterial polypeptide of 11 kDa (CAP11) and evaluation of CAP11 mRNA expression during neutrophil maturation
-
Nagaoka I, Tsutsumi-Ishii Y, Yomogida S, Yamashita T (1997) Isolation of cDNA encoding guinea pig neutrophil cationic antibacterial polypeptide of 11 kDa (CAP11) and evaluation of CAP11 mRNA expression during neutrophil maturation. J Biol Chem 272:22742-22750
-
(1997)
J Biol Chem
, vol.272
, pp. 22742-22750
-
-
Nagaoka, I.1
Tsutsumi-Ishii, Y.2
Yomogida, S.3
Yamashita, T.4
-
29
-
-
0035106913
-
Rhesus monkey (Macaca mulatta) mucosal antimicrobial peptides are close homologues of human molecules
-
Bals R, Lang C, Weiner DJ, Vogelmeier C, Welsch U, Wilson JM (2001) Rhesus monkey (Macaca mulatta) mucosal antimicrobial peptides are close homologues of human molecules. Clin Diagn Lab Immunol 8:370-375
-
(2001)
Clin Diagn Lab Immunol
, vol.8
, pp. 370-375
-
-
Bals, R.1
Lang, C.2
Weiner, D.J.3
Vogelmeier, C.4
Welsch, U.5
Wilson, J.M.6
-
30
-
-
0034806944
-
RL-37, an alpha-helical antimicrobial peptide of the rhesus monkey
-
Zhao C, Nguyen T, Boo LM, Hong T, Espiritu C, Orlov D, Wang W, Waring A, Lehrer RI (2001) RL-37, an alpha-helical antimicrobial peptide of the rhesus monkey. Antimicrob Agents Chemother 45:2695-2702
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 2695-2702
-
-
Zhao, C.1
Nguyen, T.2
Boo, L.M.3
Hong, T.4
Espiritu, C.5
Orlov, D.6
Wang, W.7
Waring, A.8
Lehrer, R.I.9
-
31
-
-
0025081012
-
Bactenecins, defense polypeptides of bovine neutrophils, are generated from precursor molecules stored in the large granules
-
Zanetti M, Litteri L, Gennaro R, Horstmann H, Romeo D (1990) Bactenecins, defense polypeptides of bovine neutrophils, are generated from precursor molecules stored in the large granules. J Cell Biol 111:1363-1371
-
(1990)
J Cell Biol
, vol.111
, pp. 1363-1371
-
-
Zanetti, M.1
Litteri, L.2
Gennaro, R.3
Horstmann, H.4
Romeo, D.5
-
32
-
-
0030861378
-
Antimicrobial peptides of phagocytes and epithelia
-
Ganz T, Weiss J (1997) Antimicrobial peptides of phagocytes and epithelia. Semin Hematol 34:343-354
-
(1997)
Semin Hematol
, vol.34
, pp. 343-354
-
-
Ganz, T.1
Weiss, J.2
-
33
-
-
0030880531
-
The human antibacterial cathelicidin, hCAP-18, is synthesized in myelocytes and metamyelocytes and localized to specific granules in neutrophils
-
Sorensen O, Arnljots K, Cowland JB, Bainton DF, Borregaard N (1997) The human antibacterial cathelicidin, hCAP-18, is synthesized in myelocytes and metamyelocytes and localized to specific granules in neutrophils. Blood 90:2796-2803
-
(1997)
Blood
, vol.90
, pp. 2796-2803
-
-
Sorensen, O.1
Arnljots, K.2
Cowland, J.B.3
Bainton, D.F.4
Borregaard, N.5
-
34
-
-
0028092047
-
Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds
-
Gallo RL, Ono M, Povsic T, Page C, Eriksson E, Klagsbrun M, Bernfield M (1994) Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds. Proc Natl Acad Sci USA 91:11035-11039
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11035-11039
-
-
Gallo, R.L.1
Ono, M.2
Povsic, T.3
Page, C.4
Eriksson, E.5
Klagsbrun, M.6
Bernfield, M.7
-
35
-
-
0032903987
-
The human cationic antimicrobial protein (hCAP18), a peptide antibiotic, is widely expressed in human squamous epithelia and colocalizes with interleukin-6
-
Frohm Nilsson M, Sandstedt B, Sorensen O, Weber G, Borregaard N, Stahle-Backdahl M (1999) The human cationic antimicrobial protein (hCAP18), a peptide antibiotic, is widely expressed in human squamous epithelia and colocalizes with interleukin-6. Infect Immun 67:2561-2566
-
(1999)
Infect Immun
, vol.67
, pp. 2561-2566
-
-
Frohm Nilsson, M.1
Sandstedt, B.2
Sorensen, O.3
Weber, G.4
Borregaard, N.5
Stahle-Backdahl, M.6
-
37
-
-
0032482980
-
The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface
-
Bals R, Wang X, Zasloff M, Wilson JM (1998) The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface. Proc Natl Acad Sci U S A 95:9541-9546
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 9541-9546
-
-
Bals, R.1
Wang, X.2
Zasloff, M.3
Wilson, J.M.4
-
38
-
-
0034946907
-
Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus
-
Dorschner RA, Pestonjamasp VK, Tamakuwala S, Ohtake T, Rudisill J, Nizet V, Agerberth B, Gudmundsson GH, Gallo RL (2001) Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus. J Invest Dermatol 117:91-97
-
(2001)
J Invest Dermatol
, vol.117
, pp. 91-97
-
-
Dorschner, R.A.1
Pestonjamasp, V.K.2
Tamakuwala, S.3
Ohtake, T.4
Rudisill, J.5
Nizet, V.6
Agerberth, B.7
Gudmundsson, G.H.8
Gallo, R.L.9
-
39
-
-
0029007198
-
hCAP-18, a cathelin/pro-bactenecin-like protein of human neutrophil specific granules
-
Cowland JB, Johnsen AH, Borregaard N (1995) hCAP-18, a cathelin/pro-bactenecin-like protein of human neutrophil specific granules. FEBS Lett 368:173-176
-
(1995)
FEBS Lett
, vol.368
, pp. 173-176
-
-
Cowland, J.B.1
Johnsen, A.H.2
Borregaard, N.3
-
40
-
-
0031028188
-
Porcine polymorphonuclear leukocytes generate extracellular microbicidal activity by elastase-mediated activation of secreted proprotegrins
-
Panyutich A, Shi J, Boutz PL, Zhao C, Ganz T (1997) Porcine polymorphonuclear leukocytes generate extracellular microbicidal activity by elastase-mediated activation of secreted proprotegrins. Infect Immun 65:978-985
-
(1997)
Infect Immun
, vol.65
, pp. 978-985
-
-
Panyutich, A.1
Shi, J.2
Boutz, P.L.3
Zhao, C.4
Ganz, T.5
-
41
-
-
0031033223
-
p15s (15-kD antimicrobial proteins) are stored in the secondary granules of Rabbit granulocytes: Implications for antibacterial synergy with the bactericidal/permeability-increasing protein in inflammatory fluids
-
Zarember K, Elsbach P, Shin-Kim K, Weiss J (1997) p15s (15-kD antimicrobial proteins) are stored in the secondary granules of Rabbit granulocytes: implications for antibacterial synergy with the bactericidal/permeability-increasing protein in inflammatory fluids. Blood 89:672-679
-
(1997)
Blood
, vol.89
, pp. 672-679
-
-
Zarember, K.1
Elsbach, P.2
Shin-Kim, K.3
Weiss, J.4
-
42
-
-
0025953533
-
Stimulus-induced maturation of probactenecins, precursors of neutrophil antimicrobial polypeptides
-
Zanetti M, Litteri L, Griffiths G, Gennaro R, Romeo D (1991) Stimulus-induced maturation of probactenecins, precursors of neutrophil antimicrobial polypeptides. J Immunol 146:4295-4300
-
(1991)
J Immunol
, vol.146
, pp. 4295-4300
-
-
Zanetti, M.1
Litteri, L.2
Griffiths, G.3
Gennaro, R.4
Romeo, D.5
-
43
-
-
0029893253
-
The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes
-
Gudmundsson GH, Agerberth B, Odeberg J, Bergman T, Olsson B, Salcedo R (1996) The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes. Eur J Biochem 238:325-332
-
(1996)
Eur J Biochem
, vol.238
, pp. 325-332
-
-
Gudmundsson, G.H.1
Agerberth, B.2
Odeberg, J.3
Bergman, T.4
Olsson, B.5
Salcedo, R.6
-
44
-
-
0026739037
-
Proteolytic cleavage by neutrophil elastase converts inactive storage proforms to antibacterial bactenecins
-
Scocchi M, Skerlavaj B, Romeo D, Gennaro R (1992) Proteolytic cleavage by neutrophil elastase converts inactive storage proforms to antibacterial bactenecins. Eur J Biochem 209: 589-595
-
(1992)
Eur J Biochem
, vol.209
, pp. 589-595
-
-
Scocchi, M.1
Skerlavaj, B.2
Romeo, D.3
Gennaro, R.4
-
45
-
-
0037039376
-
Overexpression and structural study of the cathelicidin motif of the protegrin-3 precursor
-
Sanchez JF, Wojcik F, Yang YS, Strub MP, Strub JM, Van Dorsselaer A, Martin M, Lehrer R, Ganz T, Chavanieu A, Calas B, Aumelas A (2002) Overexpression and structural study of the cathelicidin motif of the protegrin-3 precursor. Biochemistry 41:21-30
-
(2002)
Biochemistry
, vol.41
, pp. 21-30
-
-
Sanchez, J.F.1
Wojcik, F.2
Yang, Y.S.3
Strub, M.P.4
Strub, J.M.5
Van Dorsselaer, A.6
Martin, M.7
Lehrer, R.8
Ganz, T.9
Chavanieu, A.10
Calas, B.11
Aumelas, A.12
-
46
-
-
0030057777
-
Purification and structural characterization of bovine cathelicidins, precursors of antimicrobial peptides
-
Storici P, Tossi A, Lenarcic B, Romeo D (1996) Purification and structural characterization of bovine cathelicidins, precursors of antimicrobial peptides. Eur J Biochem 238:769-776
-
(1996)
Eur J Biochem
, vol.238
, pp. 769-776
-
-
Storici, P.1
Tossi, A.2
Lenarcic, B.3
Romeo, D.4
-
47
-
-
0030728214
-
Structural organization of the bovine cathelicidin gene family and identification of a novel member
-
Scocchi M, Wang S, Zanetti M (1997) Structural organization of the bovine cathelicidin gene family and identification of a novel member. FEBS Lett 417:311-315
-
(1997)
FEBS Lett
, vol.417
, pp. 311-315
-
-
Scocchi, M.1
Wang, S.2
Zanetti, M.3
-
48
-
-
0023189459
-
Identification of the probable inhibitory reactive sites of the cysteine proteinase inhibitors human cystatin C and chicken cystatin
-
Abrahamson M, Ritonja A, Brown MA, Grubb A, Machleidt W, Barrett AJ (1987) Identification of the probable inhibitory reactive sites of the cysteine proteinase inhibitors human cystatin C and chicken cystatin. J Biol Chem 262:9688-9694
-
(1987)
J Biol Chem
, vol.262
, pp. 9688-9694
-
-
Abrahamson, M.1
Ritonja, A.2
Brown, M.A.3
Grubb, A.4
Machleidt, W.5
Barrett, A.J.6
-
49
-
-
0013866176
-
Cationic proteins of polymorphonuclear leukocyte lysosomes. II. Composition, properties, and mechanism of antibacterial action
-
Zeya HI, Spitznagel JK (1966) Cationic proteins of polymorphonuclear leukocyte lysosomes. II. Composition, properties, and mechanism of antibacterial action. J Bacteriol 91:755-762
-
(1966)
J Bacteriol
, vol.91
, pp. 755-762
-
-
Zeya, H.I.1
Spitznagel, J.K.2
-
50
-
-
0019386682
-
Sequence and specificity of two antibacterial proteins involved in insect immunity
-
Steiner H, Hultmark D, Engstrom A, Bennich H, Boman HG (1981) Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature 292:246-248
-
(1981)
Nature
, vol.292
, pp. 246-248
-
-
Steiner, H.1
Hultmark, D.2
Engstrom, A.3
Bennich, H.4
Boman, H.G.5
-
51
-
-
0024460671
-
Purification, composition, and activity of two bactenecins, antibacterial peptides of bovine neutrophils
-
Gennaro R, Skerlavaj B, Romeo D (1989) Purification, composition, and activity of two bactenecins, antibacterial peptides of bovine neutrophils. Infect Immun 57:3142-3146
-
(1989)
Infect Immun
, vol.57
, pp. 3142-3146
-
-
Gennaro, R.1
Skerlavaj, B.2
Romeo, D.3
-
52
-
-
0035160960
-
The ovine cathelicidin SMAP29 kills ovine respiratory pathogens in vitro and in an ovine model of pulmonary infection
-
Brogden KA, Kalfa VC, Ackermann MR, Palmquist DE, McCray PB Jr, Tack BF (2001) The ovine cathelicidin SMAP29 kills ovine respiratory pathogens in vitro and in an ovine model of pulmonary infection. Antimicrob Agents Chemother 45:331-334
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 331-334
-
-
Brogden, K.A.1
Kalfa, V.C.2
Ackermann, M.R.3
Palmquist, D.E.4
McCray P.B., Jr.5
Tack, B.F.6
-
53
-
-
0033918174
-
The human cationic antimicrobial protein (hCAP-18) is expressed in the epithelium of human epididymis, is present in seminal plasma at high concentrations, and is attached to spermatozoa
-
Malm J, Sorensen O, Persson T, Frohm-Nilsson M, Johansson B, Bjartell A, Lilja H, Stahle-Backdahl M, Borregaard N, Egesten A (2000) The human cationic antimicrobial protein (hCAP-18) is expressed in the epithelium of human epididymis, is present in seminal plasma at high concentrations, and is attached to spermatozoa. Infect Immun 68:4297-4302
-
(2000)
Infect Immun
, vol.68
, pp. 4297-4302
-
-
Malm, J.1
Sorensen, O.2
Persson, T.3
Frohm-Nilsson, M.4
Johansson, B.5
Bjartell, A.6
Lilja, H.7
Stahle-Backdahl, M.8
Borregaard, N.9
Egesten, A.10
-
54
-
-
0030956070
-
The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders
-
Frohm M, Agerberth B, Ahangari G, Stahle-Backdahl M, Liden S, Wigzell H, Gudmundsson GH (1997) The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders. J Biol Chem 272:15258-15263
-
(1997)
J Biol Chem
, vol.272
, pp. 15258-15263
-
-
Frohm, M.1
Agerberth, B.2
Ahangari, G.3
Stahle-Backdahl, M.4
Liden, S.5
Wigzell, H.6
Gudmundsson, G.H.7
-
55
-
-
0033529627
-
The human antibacterial cathelicidin, hCAP-18, is bound to lipoproteins in plasma
-
Sorensen O, Bratt T, Johnsen AH, Madsen MT, Borregaard N (1999) The human antibacterial cathelicidin, hCAP-18, is bound to lipoproteins in plasma. J Biol Chem 274:22445-22451
-
(1999)
J Biol Chem
, vol.274
, pp. 22445-22451
-
-
Sorensen, O.1
Bratt, T.2
Johnsen, A.H.3
Madsen, M.T.4
Borregaard, N.5
-
56
-
-
0029971227
-
Biochemical and antibacterial analysis of human wound and blister fluid
-
Frohm M, Gunne H, Bergman AC, Agerberth B, Bergman T, Boman A, Liden S, Jornvall H, Boman HG (1996) Biochemical and antibacterial analysis of human wound and blister fluid. Eur J Biochem 237:86-92
-
(1996)
Eur J Biochem
, vol.237
, pp. 86-92
-
-
Frohm, M.1
Gunne, H.2
Bergman, A.C.3
Agerberth, B.4
Bergman, T.5
Boman, A.6
Liden, S.7
Jornvall, H.8
Boman, H.G.9
-
57
-
-
0035163451
-
Inhibition of neutrophil elastase prevents cathelicidin activation and impairs clearance of bacteria from wounds
-
Cole AM, Shi J, Ceccarelli A, Kim YH, Park A, Ganz T (2001) Inhibition of neutrophil elastase prevents cathelicidin activation and impairs clearance of bacteria from wounds. Blood 97:297-304
-
(2001)
Blood
, vol.97
, pp. 297-304
-
-
Cole, A.M.1
Shi, J.2
Ceccarelli, A.3
Kim, Y.H.4
Park, A.5
Ganz, T.6
-
58
-
-
0035877995
-
Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3
-
Sorensen OE, Follin P, Johnsen AH, Calafat J, Tjabringa GS, Hiemstra PS, Borregaard N (2001) Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3. Blood 97:3951-3959
-
(2001)
Blood
, vol.97
, pp. 3951-3959
-
-
Sorensen, O.E.1
Follin, P.2
Johnsen, A.H.3
Calafat, J.4
Tjabringa, G.S.5
Hiemstra, P.S.6
Borregaard, N.7
-
59
-
-
0033178532
-
Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: Relevance to the molecular basis for its non-cell-selective activity
-
Oren Z, Lerman JC, Gudmundsson GH, Agerberth B, Shai Y (1999) Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity. Biochem J 341:501-513
-
(1999)
Biochem J
, vol.341
, pp. 501-513
-
-
Oren, Z.1
Lerman, J.C.2
Gudmundsson, G.H.3
Agerberth, B.4
Shai, Y.5
-
60
-
-
0032488904
-
Conformation-dependent antibacterial activity of the naturally occurring human peptide LL-37
-
Johansson J, Gudmundsson GH, Rottenberg ME, Berndt KD, Agerberth B (1998) Conformation-dependent antibacterial activity of the naturally occurring human peptide LL-37. J Biol Chem 273:3718-3724
-
(1998)
J Biol Chem
, vol.273
, pp. 3718-3724
-
-
Johansson, J.1
Gudmundsson, G.H.2
Rottenberg, M.E.3
Berndt, K.D.4
Agerberth, B.5
-
61
-
-
0031686776
-
Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils
-
Turner J, Cho Y, Dinh NN, Waring AJ, Lehrer RI (1998) Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils. Antimicrob Agents Chemother 42: 2206-2214
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 2206-2214
-
-
Turner, J.1
Cho, Y.2
Dinh, N.N.3
Waring, A.J.4
Lehrer, R.I.5
-
62
-
-
0033937030
-
Activity of cecropin P1 and FA-LL-37 against urogenital microflora
-
Smeianov V, Scott K, Reid G (2000) Activity of cecropin P1 and FA-LL-37 against urogenital microflora. Microbes Infect 2:773-777
-
(2000)
Microbes Infect
, vol.2
, pp. 773-777
-
-
Smeianov, V.1
Scott, K.2
Reid, G.3
-
63
-
-
0033926971
-
Sensitivity of Acti-nobacillus actinomycetemcomitans and Capnocytophaga spp. to the bactericidal action of LL-37: A cathelicidin found in human leukocytes and epithelium
-
Tanaka D, Miyasaki KT, Lehrer RI (2000) Sensitivity of Acti-nobacillus actinomycetemcomitans and Capnocytophaga spp. to the bactericidal action of LL-37: a cathelicidin found in human leukocytes and epithelium. Oral Microbiol Immunol 15:226-231
-
(2000)
Oral Microbiol Immunol
, vol.15
, pp. 226-231
-
-
Tanaka, D.1
Miyasaki, K.T.2
Lehrer, R.I.3
-
64
-
-
0027474382
-
Defensins: Antimicrobial and cytotoxic peptides of mammalian cells
-
Lehrer RI, Lichtenstein AK, Ganz T (1993) Defensins: antimicrobial and cytotoxic peptides of mammalian cells. Annu Rev Immunol 11:105-128
-
(1993)
Annu Rev Immunol
, vol.11
, pp. 105-128
-
-
Lehrer, R.I.1
Lichtenstein, A.K.2
Ganz, T.3
-
65
-
-
0030949875
-
Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis
-
Goldman MJ, Anderson GM, Stolzenberg ED, Kari UP, Zasloff M, Wilson JM (1997) Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis. Cell 88:553-560
-
(1997)
Cell
, vol.88
, pp. 553-560
-
-
Goldman, M.J.1
Anderson, G.M.2
Stolzenberg, E.D.3
Kari, U.P.4
Zasloff, M.5
Wilson, J.M.6
-
67
-
-
0028949278
-
Human CAP18: A novel antimicrobial lipopolysaccharide-binding protein
-
Larrick JW, Hirata M, Balint RF, Lee J, Zhong J, Wright SC (1995) Human CAP18: a novel antimicrobial lipopolysaccharide-binding protein. Infect Immun 63:1291-1297
-
(1995)
Infect Immun
, vol.63
, pp. 1291-1297
-
-
Larrick, J.W.1
Hirata, M.2
Balint, R.F.3
Lee, J.4
Zhong, J.5
Wright, S.C.6
-
68
-
-
0034596945
-
LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells
-
De Y, Chen Q, Schmidt AP, Anderson GM, Wang JM, Wooters J, Oppenheim JJ, Chertov O (2000) LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells. J Exp Med 192:1069-1074
-
(2000)
J Exp Med
, vol.192
, pp. 1069-1074
-
-
De, Y.1
Chen, Q.2
Schmidt, A.P.3
Anderson, G.M.4
Wang, J.M.5
Wooters, J.6
Oppenheim, J.J.7
Chertov, O.8
-
69
-
-
0034332193
-
The human antimicrobial and chemotactic peptides LL-37 and alpha-defensins are expressed by specific lymphocyte and monocyte populations
-
Agerberth B, Charo J, Werr J, Olsson B, Idali F, Lindbom L, Kiessling R, Jornvall H, Wigzell H, Gudmundsson GH (2000) The human antimicrobial and chemotactic peptides LL-37 and alpha-defensins are expressed by specific lymphocyte and monocyte populations. Blood 96:3086-3093
-
(2000)
Blood
, vol.96
, pp. 3086-3093
-
-
Agerberth, B.1
Charo, J.2
Werr, J.3
Olsson, B.4
Idali, F.5
Lindbom, L.6
Kiessling, R.7
Jornvall, H.8
Wigzell, H.9
Gudmundsson, G.H.10
-
70
-
-
0034998629
-
Participation of mammalian defensins and cathelicidins in anti-microbial immunity: Receptors and activities of human defensins and cathelicidin (LL-37)
-
Yang D, Chertov O, Oppenheim JJ (2001) Participation of mammalian defensins and cathelicidins in anti-microbial immunity: receptors and activities of human defensins and cathelicidin (LL-37). J Leukoc Biol 69:691-697
-
(2001)
J Leukoc Biol
, vol.69
, pp. 691-697
-
-
Yang, D.1
Chertov, O.2
Oppenheim, J.J.3
-
71
-
-
0035058454
-
Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D (2) production from mast cells
-
Niyonsaba F, Someya A, Hirata M, Ogawa H, Nagaoka I (2001) Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D (2) production from mast cells. Eur J Immunol 31:1066-1075
-
(2001)
Eur J Immunol
, vol.31
, pp. 1066-1075
-
-
Niyonsaba, F.1
Someya, A.2
Hirata, M.3
Ogawa, H.4
Nagaoka, I.5
-
72
-
-
0031925180
-
Protective effects of a human 18-kilodalton cationic antimicrobial protein (CAP18)-derived peptide against murine endotoxemia
-
Kirikae T, Hirata M, Yamasu H, Kirikae F. Tamura, H, Kayama F, Nakatsuka K, Yokochi T, Nakano M (1998) Protective effects of a human 18-kilodalton cationic antimicrobial protein (CAP18)-derived peptide against murine endotoxemia. Infect Immun 66:1861-1868
-
(1998)
Infect Immun
, vol.66
, pp. 1861-1868
-
-
Kirikae, T.1
Hirata, M.2
Yamasu, H.3
Kirikae, F.4
Tamura, H.5
Kayama, F.6
Nakatsuka, K.7
Yokochi, T.8
Nakano, M.9
-
73
-
-
0032708355
-
Augmentation of innate host defense by expression of a cathelicidin antimicrobial peptide
-
Bals R, Weiner DJ, Moscioni AD, Meegalla RL, Wilson JM (1999) Augmentation of innate host defense by expression of a cathelicidin antimicrobial peptide. Infect Immun 67:6084-6089
-
(1999)
Infect Immun
, vol.67
, pp. 6084-6089
-
-
Bals, R.1
Weiner, D.J.2
Moscioni, A.D.3
Meegalla, R.L.4
Wilson, J.M.5
-
74
-
-
0033560645
-
Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model
-
Bals R, Weiner DJ, Meegalla RL, Wilson, JM (1999) Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model. J Clin Invest 103:1113-1117
-
(1999)
J Clin Invest
, vol.103
, pp. 1113-1117
-
-
Bals, R.1
Weiner, D.J.2
Meegalla, R.L.3
Wilson, J.M.4
-
75
-
-
0035936156
-
Innate antimicrobial peptide protects the skin from invasive bacterial infection
-
Nizet V, Ohtake T, Lauth X, Trowbridge J, Rudisill J, Dorschner RA, Pestonjamasp V, Piraino J, Huttner K, Gallo RL (2001) Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature 414:454-457
-
(2001)
Nature
, vol.414
, pp. 454-457
-
-
Nizet, V.1
Ohtake, T.2
Lauth, X.3
Trowbridge, J.4
Rudisill, J.5
Dorschner, R.A.6
Pestonjamasp, V.7
Piraino, J.8
Huttner, K.9
Gallo, R.L.10
-
76
-
-
0027399332
-
The skin immune system: Progress in cutaneous biology
-
Bos JD, Kapsenberg ML (1993) The skin immune system: progress in cutaneous biology. Immunol Today 14:75-78
-
(1993)
Immunol Today
, vol.14
, pp. 75-78
-
-
Bos, J.D.1
Kapsenberg, M.L.2
-
77
-
-
0032803143
-
Reduced antimicrobial peptide expression in human burn wounds
-
Milner SM, Ortega MR (1999) Reduced antimicrobial peptide expression in human burn wounds. Burns 25:411-413
-
(1999)
Burns
, vol.25
, pp. 411-413
-
-
Milner, S.M.1
Ortega, M.R.2
-
78
-
-
0033825243
-
Human beta defensin is absent in burn blister fluid
-
Ortega MR, Ganz T, Milner SM (2000) Human beta defensin is absent in burn blister fluid. Burns 26:724-726
-
(2000)
Burns
, vol.26
, pp. 724-726
-
-
Ortega, M.R.1
Ganz, T.2
Milner, S.M.3
-
79
-
-
2042513493
-
Magainins, a class of antimicrobial peptides from Xenopus skin: Isolation, characterization of two active forms, and partial cDNA sequence of a precursor
-
Zasloff M (1987) Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc Natl Acad Sci U S A 84:5449-5453
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 5449-5453
-
-
Zasloff, M.1
-
80
-
-
0035126317
-
Downregulation of bactericidal peptides in enteric infections: A novel immune escape mechanism with bacterial DNA as a potential regulator
-
Islam D, Bandholtz L, Nilsson J, Wigzell H, Christensson B, Agerberth B, Gudmundsson G (2001) Downregulation of bactericidal peptides in enteric infections: a novel immune escape mechanism with bacterial DNA as a potential regulator. Nat Med 7:180-185
-
(2001)
Nat Med
, vol.7
, pp. 180-185
-
-
Islam, D.1
Bandholtz, L.2
Nilsson, J.3
Wigzell, H.4
Christensson, B.5
Agerberth, B.6
Gudmundsson, G.7
-
81
-
-
0032734313
-
Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium
-
O'Neil DA, Porter EM, Elewaut D, Anderson GM, Eckmann L, Ganz T, Kagnoff MF (1999) Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium. J Immunol 163:6718-6724
-
(1999)
J Immunol
, vol.163
, pp. 6718-6724
-
-
O'Neil, D.A.1
Porter, E.M.2
Elewaut, D.3
Anderson, G.M.4
Eckmann, L.5
Ganz, T.6
Kagnoff, M.F.7
-
82
-
-
0344483901
-
Production of beta-defensin antimicrobial peptides by the oral mucosa and salivary glands
-
Mathews M, Jia HP, Guthmiller JM, Losh G, Graham S, Johnson GK, Tack BF, McCray PB Jr (1999) Production of beta-defensin antimicrobial peptides by the oral mucosa and salivary glands. Infect Immun 67:2740-2745
-
(1999)
Infect Immun
, vol.67
, pp. 2740-2745
-
-
Mathews, M.1
Jia, H.P.2
Guthmiller, J.M.3
Losh, G.4
Graham, S.5
Johnson, G.K.6
Tack, B.F.7
McCray P.B., Jr.8
-
83
-
-
0030602220
-
Structural, functional analysis and localization of the human CAP18 gene
-
Larrick JW, Lee J, Ma S, Li X, Francke U, Wright SC, Balint RF (1996) Structural, functional analysis and localization of the human CAP18 gene. FEBS Lett 398:74-80
-
(1996)
FEBS Lett
, vol.398
, pp. 74-80
-
-
Larrick, J.W.1
Lee, J.2
Ma, S.3
Li, X.4
Francke, U.5
Wright, S.C.6
Balint, R.F.7
-
84
-
-
0029129210
-
Structure of the gene for porcine peptide antibiotic PR-39, a cathelin gene family member: Comparative mapping of the locus for the human peptide antibiotic FALL-39
-
Gudmundsson GH, Magnusson KP, Chowdhary BP, Johansson M, Andersson L, Boman HG (1995) Structure of the gene for porcine peptide antibiotic PR-39, a cathelin gene family member: comparative mapping of the locus for the human peptide antibiotic FALL-39. Proc Natl Acad Sci U S A 92:7085-7089
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7085-7089
-
-
Gudmundsson, G.H.1
Magnusson, K.P.2
Chowdhary, B.P.3
Johansson, M.4
Andersson, L.5
Boman, H.G.6
-
85
-
-
0028933794
-
Peptide antibiotics and their role in innate immunity
-
Boman HG (1995) Peptide antibiotics and their role in innate immunity. Annu Rev Immunol 13:61-92
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 61-92
-
-
Boman, H.G.1
-
86
-
-
0033981142
-
Transcriptional regulation of beta-defensin gene expression in tracheal epithelial cells
-
Diamond G, Kaiser V, Rhodes J, Russell JP, Bevins CL (2000) Transcriptional regulation of beta-defensin gene expression in tracheal epithelial cells. Infect Immun 68:113-119
-
(2000)
Infect Immun
, vol.68
, pp. 113-119
-
-
Diamond, G.1
Kaiser, V.2
Rhodes, J.3
Russell, J.P.4
Bevins, C.L.5
-
87
-
-
0035190972
-
Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein
-
Birchler T, Seibl R, Buchner K, Loeliger S, Seger R, Hossle JP, Aguzzi A, Lauener RP (2001) Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein. Eur J Immunol 31:3131-3137
-
(2001)
Eur J Immunol
, vol.31
, pp. 3131-3137
-
-
Birchler, T.1
Seibl, R.2
Buchner, K.3
Loeliger, S.4
Seger, R.5
Hossle, J.P.6
Aguzzi, A.7
Lauener, R.P.8
-
88
-
-
0033377813
-
Neutrophil antibacterial peptides, multifunctional effector molecules in the mammalian immune system
-
Gudmundsson GH, Agerberth B (1999) Neutrophil antibacterial peptides, multifunctional effector molecules in the mammalian immune system. J Immunol Methods 232:45-54
-
(1999)
J Immunol Methods
, vol.232
, pp. 45-54
-
-
Gudmundsson, G.H.1
Agerberth, B.2
-
89
-
-
0034832028
-
Processing site and gene structure for the murine antimicrobial peptide
-
Pestonjamasp VK, Huttner KH, Gallo, RL (2001) Processing site and gene structure for the murine antimicrobial peptide. CRAMP Peptides. 22:1643-1650
-
(2001)
CRAMP Peptides
, vol.22
, pp. 1643-1650
-
-
Pestonjamasp, V.K.1
Huttner, K.H.2
Gallo, R.L.3
-
90
-
-
0028853334
-
Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages
-
Tanaka T, Akira S, Yoshida K, Umemoto M, Yoneda Y, Shirafuji N, Fujiwara H, Suematsu S, Yoshida N, Kishimoto T (1995) Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages. Cell 80:353-361
-
(1995)
Cell
, vol.80
, pp. 353-361
-
-
Tanaka, T.1
Akira, S.2
Yoshida, K.3
Umemoto, M.4
Yoneda, Y.5
Shirafuji, N.6
Fujiwara, H.7
Suematsu, S.8
Yoshida, N.9
Kishimoto, T.10
-
91
-
-
0034653395
-
Role of CCAAT/enhancer-binding protein site in transcription of human neutrophil peptide-1 and -3 defensin genes
-
Tsutsumi-Ishii Y, Hasebe T, Nagaoka I (2000) Role of CCAAT/enhancer-binding protein site in transcription of human neutrophil peptide-1 and -3 defensin genes. J Immunol 164:3264-3273
-
(2000)
J Immunol
, vol.164
, pp. 3264-3273
-
-
Tsutsumi-Ishii, Y.1
Hasebe, T.2
Nagaoka, I.3
-
92
-
-
0028839913
-
Structures of genes for two cathelin-associated antimicrobial peptides: Prophenin-2 and PR-39
-
Zhao C, Ganz T, Lehrer RI (1995) Structures of genes for two cathelin-associated antimicrobial peptides: prophenin-2 and PR-39. FEBS Lett 376:130-134
-
(1995)
FEBS Lett
, vol.376
, pp. 130-134
-
-
Zhao, C.1
Ganz, T.2
Lehrer, R.I.3
-
93
-
-
0030720063
-
Effect of glucocorticoids on the synthesis of antimicrobial peptides in amphibian skin
-
Simmaco M, Boman A, Mangoni ML, Mignogna G, Miele R, Barra D, Boman HG (1997) Effect of glucocorticoids on the synthesis of antimicrobial peptides in amphibian skin. FEBS Lett 416:273-275
-
(1997)
FEBS Lett
, vol.416
, pp. 273-275
-
-
Simmaco, M.1
Boman, A.2
Mangoni, M.L.3
Mignogna, G.4
Miele, R.5
Barra, D.6
Boman, H.G.7
-
94
-
-
0029877550
-
Coordinate induction of two antibiotic genes in tracheal epithelial cells exposed to the inflammatory mediators lipopolysaccharide and tumor necrosis factor alpha
-
Russell JP, Diamond G, Tarver AP, Scanlin TF, Bevins CL (1996) Coordinate induction of two antibiotic genes in tracheal epithelial cells exposed to the inflammatory mediators lipopolysaccharide and tumor necrosis factor alpha. Infect Immun 64:1565-1568
-
(1996)
Infect Immun
, vol.64
, pp. 1565-1568
-
-
Russell, J.P.1
Diamond, G.2
Tarver, A.P.3
Scanlin, T.F.4
Bevins, C.L.5
-
95
-
-
0033231036
-
Myeloid transcription factor C/EBPepsilon is involved in the positive regulation of lactoferrin gene expression in neutrophils
-
Verbeek W, Lekstrom-Himes J, Park DJ, Dang PM, Vuong PT, Kawano S, Babior BM, Xanthopoulos K, Koeffler HP (1999) Myeloid transcription factor C/EBPepsilon is involved in the positive regulation of lactoferrin gene expression in neutrophils. Blood 94:3141-3150
-
(1999)
Blood
, vol.94
, pp. 3141-3150
-
-
Verbeek, W.1
Lekstrom-Himes, J.2
Park, D.J.3
Dang, P.M.4
Vuong, P.T.5
Kawano, S.6
Babior, B.M.7
Xanthopoulos, K.8
Koeffler, H.P.9
-
96
-
-
0031836105
-
Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis
-
Belaaouaj A, McCarthy R, Baumann M, Gao Z, Ley TJ, Abraham SN, Shapiro SD (1998) Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis. Nat Med 4:615-618
-
(1998)
Nat Med
, vol.4
, pp. 615-618
-
-
Belaaouaj, A.1
McCarthy, R.2
Baumann, M.3
Gao, Z.4
Ley, T.J.5
Abraham, S.N.6
Shapiro, S.D.7
-
97
-
-
0033214433
-
Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense
-
Wilson CL, Ouellette AJ, Satchell DP, Ayabe T, Lopez-Boado YS, Stratman JL, Hultgren SJ, Matrisian LM, Parks WC (1999) Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense. Science 286:113-117
-
(1999)
Science
, vol.286
, pp. 113-117
-
-
Wilson, C.L.1
Ouellette, A.J.2
Satchell, D.P.3
Ayabe, T.4
Lopez-Boado, Y.S.5
Stratman, J.L.6
Hultgren, S.J.7
Matrisian, L.M.8
Parks, W.C.9
-
98
-
-
0034669924
-
Bacterial killing is enhanced by expression of lysozyme in the lungs of transgenic mice
-
Akinbi HT, Epaud R, Bhatt H, Weaver TE (2000) Bacterial killing is enhanced by expression of lysozyme in the lungs of transgenic mice. J Immunol 165:5760-5766
-
(2000)
J Immunol
, vol.165
, pp. 5760-5766
-
-
Akinbi, H.T.1
Epaud, R.2
Bhatt, H.3
Weaver, T.E.4
-
99
-
-
0026349223
-
Amino acid sequence of PR-39. Isolation from pig intestine of a new member of the family of proline-arginine-rich antibacterial peptides
-
Agerberth B, Lee JY, Bergman T, Carlquist M, Boman HG, Mutt V, Jornvall H (1991) Amino acid sequence of PR-39. Isolation from pig intestine of a new member of the family of proline-arginine-rich antibacterial peptides. Eur J Biochem 202:849-854
-
(1991)
Eur J Biochem
, vol.202
, pp. 849-854
-
-
Agerberth, B.1
Lee, J.Y.2
Bergman, T.3
Carlquist, M.4
Boman, H.G.5
Mutt, V.6
Jornvall, H.7
-
100
-
-
0027443966
-
A novel cDNA sequence encoding a pig leukocyte antimicrobial peptide with a cathelin-like pro-sequence
-
Storici P, Zanetti M (1993) A novel cDNA sequence encoding a pig leukocyte antimicrobial peptide with a cathelin-like pro-sequence. Biochem Biophys Res Commun 196: 1363-1368
-
(1993)
Biochem Biophys Res Commun
, vol.196
, pp. 1363-1368
-
-
Storici, P.1
Zanetti, M.2
-
101
-
-
0030670074
-
Macrophage-dependent regulation of syndecan gene expression
-
Li J, Brown LF, Laham RJ, Volk R, Simons M (1997) Macrophage-dependent regulation of syndecan gene expression. Circ Res 81:785-796
-
(1997)
Circ Res
, vol.81
, pp. 785-796
-
-
Li, J.1
Brown, L.F.2
Laham, R.J.3
Volk, R.4
Simons, M.5
-
102
-
-
0030032395
-
Antibacterial activity of a synthetic peptide (PR-26) derived from PR- 39, a proline-arginine-rich neutrophil antimicrobial peptide
-
Shi J, Ross CR, Chengappa MM, Sylte MJ, McVey DS, Blecha F (1996) Antibacterial activity of a synthetic peptide (PR-26) derived from PR- 39, a proline-arginine-rich neutrophil antimicrobial peptide. Antimicrob Agents Chemother 40:115-121
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 115-121
-
-
Shi, J.1
Ross, C.R.2
Chengappa, M.M.3
Sylte, M.J.4
McVey, D.S.5
Blecha, F.6
-
103
-
-
0035001927
-
In vitro activity of PR-39, a proline-arginine-rich peptide, against susceptible and multi-drug-resistant Mycobacterium tuberculosis
-
Linde CM, Hoffner SE, Refai E, Andersson M (2001) In vitro activity of PR-39, a proline-arginine-rich peptide, against susceptible and multi-drug-resistant Mycobacterium tuberculosis. J Antimicrob Chemother 47:575-580
-
(2001)
J Antimicrob Chemother
, vol.47
, pp. 575-580
-
-
Linde, C.M.1
Hoffner, S.E.2
Refai, E.3
Andersson, M.4
-
104
-
-
0030043634
-
In vitro activity of the antimicrobial peptides human and rabbit defensins and porcine leukocyte protegrin against Mycobacterium tuberculosis
-
Miyakawa Y, Ratnakar P, Rao AG, Costello ML, Mathieu-Costello O, Lehrer RI, Catanzaro, A (1996) In vitro activity of the antimicrobial peptides human and rabbit defensins and porcine leukocyte protegrin against Mycobacterium tuberculosis. Infect Immun 64:926-932
-
(1996)
Infect Immun
, vol.64
, pp. 926-932
-
-
Miyakawa, Y.1
Ratnakar, P.2
Rao, A.G.3
Costello, M.L.4
Mathieu-Costello, O.5
Lehrer, R.I.6
Catanzaro, A.7
-
105
-
-
0026437470
-
Activity of defensins from human neutrophilic granulocytes against Mycobacterium avium-Mycobacterium intracellulare
-
Ogata K, Linzer BA, Zuberi RI, Ganz T, Lehrer RI, Catanzaro A (1992) Activity of defensins from human neutrophilic granulocytes against Mycobacterium avium-Mycobacterium intracellulare. Infect Immun 60:4720-4725
-
(1992)
Infect Immun
, vol.60
, pp. 4720-4725
-
-
Ogata, K.1
Linzer, B.A.2
Zuberi, R.I.3
Ganz, T.4
Lehrer, R.I.5
Catanzaro, A.6
-
106
-
-
0027216093
-
Mechanisms of action on Escherichia coli of cecropin P1 and PR-39, two antibacterial peptides from pig intestine
-
Boman HG, Agerberth B, Boman A (1993) Mechanisms of action on Escherichia coli of cecropin P1 and PR-39, two antibacterial peptides from pig intestine. Infect Immun 61:2978-2984
-
(1993)
Infect Immun
, vol.61
, pp. 2978-2984
-
-
Boman, H.G.1
Agerberth, B.2
Boman, A.3
-
107
-
-
0032582684
-
PR-39, a syndecan-inducing antimicrobial peptide, binds and affects p130 (Cas)
-
Chan YR, Gallo RL (1998) PR-39, a syndecan-inducing antimicrobial peptide, binds and affects p130 (Cas). J Biol Chem 273:28978-28985
-
(1998)
J Biol Chem
, vol.273
, pp. 28978-28985
-
-
Chan, Y.R.1
Gallo, R.L.2
-
108
-
-
0029664907
-
PR-39, a proline-rich antibacterial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47 phox
-
Shi J, Ross CR, Leto TL, Blecha F (1996) PR-39, a proline-rich antibacterial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47 phox. Proc Natl Acad Sci USA 93:6014-6018
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6014-6018
-
-
Shi, J.1
Ross, C.R.2
Leto, T.L.3
Blecha, F.4
-
109
-
-
0030976983
-
Chemoattractant properties of PR-39, a neutrophil antibacterial peptide
-
Huang HJ, Ross CR, Blecha F (1997) Chemoattractant properties of PR-39, a neutrophil antibacterial peptide. J Leukoc Biol 61:624-629
-
(1997)
J Leukoc Biol
, vol.61
, pp. 624-629
-
-
Huang, H.J.1
Ross, C.R.2
Blecha, F.3
-
110
-
-
0034536382
-
PR-39, a potent neutrophil inhibitor, attenuates myocardial ischemia-reperfusion injury in mice
-
Hoffmeyer MR, Scalia R, Ross CR, Jones SP, Lefer DJ (2000) PR-39, a potent neutrophil inhibitor, attenuates myocardial ischemia-reperfusion injury in mice. Am J Physiol Heart Circ Physiol 279:H2824-H2828
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.279
-
-
Hoffmeyer, M.R.1
Scalia, R.2
Ross, C.R.3
Jones, S.P.4
Lefer, D.J.5
-
111
-
-
0032875198
-
Proline-rich antimicrobial peptide, PR-39 gene transduction altered invasive activity and actin structure in human hepatocellular carcinoma cells
-
Ohtake T, Fujimoto Y, Ikuta K, Saito H, Ohhira M, Ono M, Kohgo Y (1999) Proline-rich antimicrobial peptide, PR-39 gene transduction altered invasive activity and actin structure in human hepatocellular carcinoma cells. Br J Cancer 81:393-403
-
(1999)
Br J Cancer
, vol.81
, pp. 393-403
-
-
Ohtake, T.1
Fujimoto, Y.2
Ikuta, K.3
Saito, H.4
Ohhira, M.5
Ono, M.6
Kohgo, Y.7
-
112
-
-
0032885893
-
PR-39, a proline/arginine-rich antimicrobial peptide, prevents post-ischemic microvascular dysfunction
-
Korthuis RJ, Gute DC, Blecha F, Ross CR (1999) PR-39, a proline/arginine-rich antimicrobial peptide, prevents post-ischemic microvascular dysfunction. Am J Physiol 277: H1007-H1013
-
(1999)
Am J Physiol
, vol.277
-
-
Korthuis, R.J.1
Gute, D.C.2
Blecha, F.3
Ross, C.R.4
-
113
-
-
0032487361
-
Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+
-
Al-Mehdi AB, Zhao G, Dodia C, Tozawa K, Costa K, Muzykantov V, Ross C, Blecha F, Dinauer M, Fisher AB (1998) Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+. Circ Res 83:730-737
-
(1998)
Circ Res
, vol.83
, pp. 730-737
-
-
Al-Mehdi, A.B.1
Zhao, G.2
Dodia, C.3
Tozawa, K.4
Costa, K.5
Muzykantov, V.6
Ross, C.7
Blecha, F.8
Dinauer, M.9
Fisher, A.B.10
-
114
-
-
0032892736
-
Cathelicidin gene expression in porcine tissues: Roles in ontogeny and tissue specificity
-
Wu H, Zhang G, Ross CR, Blecha F (1999) Cathelicidin gene expression in porcine tissues: roles in ontogeny and tissue specificity. Infect Immun 67:439-442
-
(1999)
Infect Immun
, vol.67
, pp. 439-442
-
-
Wu, H.1
Zhang, G.2
Ross, C.R.3
Blecha, F.4
-
115
-
-
0030578443
-
Differentiation-associated antimicrobial functions in human colon adenocarcinoma cell lines
-
Bernet-Camard MF, Coconnier MH, Hudault S, Servin AL (1996) Differentiation-associated antimicrobial functions in human colon adenocarcinoma cell lines. Exp Cell Res 226:80-89
-
(1996)
Exp Cell Res
, vol.226
, pp. 80-89
-
-
Bernet-Camard, M.F.1
Coconnier, M.H.2
Hudault, S.3
Servin, A.L.4
-
116
-
-
0033970878
-
PR39, a peptide regulator of angiogenesis
-
Li J, Post M, Volk R, Gao Y, Li M, Metais C, Sato K, Tsai J, Aird W, Rosenberg RD, Hampton TG, Sellke F, Carmeliet P, Simons M (2000) PR39, a peptide regulator of angiogenesis. Nat Med 6:49-55
-
(2000)
Nat Med
, vol.6
, pp. 49-55
-
-
Li, J.1
Post, M.2
Volk, R.3
Gao, Y.4
Li, M.5
Metais, C.6
Sato, K.7
Tsai, J.8
Aird, W.9
Rosenberg, R.D.10
Hampton, T.G.11
Sellke, F.12
Carmeliet, P.13
Simons, M.14
-
117
-
-
0033797218
-
Regulation of cathelicidin gene expression: Induction by lipopolysaccharide, interleukin-6, retinoic acid, and Salmonella enterica serovar typhimurium infection
-
Wu H, Zhang G, Minton JE, Ross CR, Blecha F (2000) Regulation of cathelicidin gene expression: induction by lipopolysaccharide, interleukin-6, retinoic acid, and Salmonella enterica serovar typhimurium infection. Infect Immun 68:5552-5558
-
(2000)
Infect Immun
, vol.68
, pp. 5552-5558
-
-
Wu, H.1
Zhang, G.2
Minton, J.E.3
Ross, C.R.4
Blecha, F.5
-
118
-
-
0027169823
-
Protegrins: Leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins
-
Kokryakov VN, Harwig SS, Panyutich EA, Shevchenko AA, Aleshina GM, Shamova OV, Korneva HA, Lehrer RI (1993) Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins. FEBS Lett 327:231-236
-
(1993)
FEBS Lett
, vol.327
, pp. 231-236
-
-
Kokryakov, V.N.1
Harwig, S.S.2
Panyutich, E.A.3
Shevchenko, A.A.4
Aleshina, G.M.5
Shamova, O.V.6
Korneva, H.A.7
Lehrer, R.I.8
-
119
-
-
0029015666
-
The structure of porcine protegrin genes
-
Zhao C, Ganz T, Lehrer RI (1995) The structure of porcine protegrin genes. FEBS Lett 368:197-202
-
(1995)
FEBS Lett
, vol.368
, pp. 197-202
-
-
Zhao, C.1
Ganz, T.2
Lehrer, R.I.3
-
120
-
-
0029831079
-
Intramolecular disulfide bonds enhance the antimicrobial and lytic activities of protegrins at physiological sodium chloride concentrations
-
Harwig SS, Waring A, Yang HJ, Cho Y, Tan L, Lehrer RI (1996) Intramolecular disulfide bonds enhance the antimicrobial and lytic activities of protegrins at physiological sodium chloride concentrations. Eur J Biochem 240:352-357
-
(1996)
Eur J Biochem
, vol.240
, pp. 352-357
-
-
Harwig, S.S.1
Waring, A.2
Yang, H.J.3
Cho, Y.4
Tan, L.5
Lehrer, R.I.6
-
121
-
-
0029040564
-
Synthesis of protegrin-related peptides and their antibacterial and anti-human immunodeficiency virus activity
-
Tamamura H, Murakami T, Horiuchi S, Sugihara K, Otaka A, Takada W, Ibuka T, Waki M, Yamamoto N, Fujii N (1995) Synthesis of protegrin-related peptides and their antibacterial and anti-human immunodeficiency virus activity. Chem Pharm Bull (Tokyo) 43:853-858
-
(1995)
Chem Pharm Bull (Tokyo)
, vol.43
, pp. 853-858
-
-
Tamamura, H.1
Murakami, T.2
Horiuchi, S.3
Sugihara, K.4
Otaka, A.5
Takada, W.6
Ibuka, T.7
Waki, M.8
Yamamoto, N.9
Fujii, N.10
-
122
-
-
0030855146
-
Protegrin-1: A broad-spectrum, rapidly microbicidal peptide with in vivo activity
-
Steinberg DA, Hurst MA, Fujii CA, Kung AH, Ho JF, Cheng FC, Loury DJ, Fiddes JC (1997) Protegrin-1: a broad-spectrum, rapidly microbicidal peptide with in vivo activity. Antimicrob Agents Chemother 41:1738-1742
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 1738-1742
-
-
Steinberg, D.A.1
Hurst, M.A.2
Fujii, C.A.3
Kung, A.H.4
Ho, J.F.5
Cheng, F.C.6
Loury, D.J.7
Fiddes, J.C.8
-
123
-
-
0034954221
-
Protegrin-1 enhances bacterial killing in thermally injured skin
-
Steinstraesser L, Klein RD, Aminlari A, Fan MH, Khilanani V, Remick,DG, Su GL, Wang SC (2001) Protegrin-1 enhances bacterial killing in thermally injured skin. Crit Care Med 29:1431-1437
-
(2001)
Crit Care Med
, vol.29
, pp. 1431-1437
-
-
Steinstraesser, L.1
Klein, R.D.2
Aminlari, A.3
Fan, M.H.4
Khilanani, V.5
Remick, D.G.6
Su, G.L.7
Wang, S.C.8
-
124
-
-
0033605557
-
Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides
-
Peschel A, Otto M, Jack RW, Kalbacher H, Jung G, Gotz F (1999) Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides. J Biol Chem 274:8405-8410
-
(1999)
J Biol Chem
, vol.274
, pp. 8405-8410
-
-
Peschel, A.1
Otto, M.2
Jack, R.W.3
Kalbacher, H.4
Jung, G.5
Gotz, F.6
-
125
-
-
0037087422
-
Antimicrobial peptides initiate IL-1beta posttranslational processing: A novel role beyond innate immunity
-
Perregaux DG, Bhavsar K, Contillo L, Shi J, Gabel CA (2002) Antimicrobial Peptides Initiate IL-1beta Posttranslational Processing: A Novel Role Beyond Innate Immunity. J Immunol 168:3024-3032
-
(2002)
J Immunol
, vol.168
, pp. 3024-3032
-
-
Perregaux, D.G.1
Bhavsar, K.2
Contillo, L.3
Shi, J.4
Gabel, C.A.5
-
126
-
-
0033858613
-
Development of protegrins for the treatment and prevention of oral mucositis: Structure-activity relationships of synthetic protegrin analogues
-
Chen J, Falla TJ, Liu H, Hurst MA, Fujii CA, Mosca DA, Embree JR, Loury DJ, Radel PA, Cheng Chang C, Gu L, Fiddes JC (2000) Development of protegrins for the treatment and prevention of oral mucositis: structure-activity relationships of synthetic protegrin analogues. Biopolymers 55:88-98
-
(2000)
Biopolymers
, vol.55
, pp. 88-98
-
-
Chen, J.1
Falla, T.J.2
Liu, H.3
Hurst, M.A.4
Fujii, C.A.5
Mosca, D.A.6
Embree, J.R.7
Loury, D.J.8
Radel, P.A.9
Cheng Chang, C.10
Gu, L.11
Fiddes, J.C.12
-
127
-
-
0033124110
-
Effect of local application of the antimicrobial peptide IB-367 on the incidence and severity of oral mucositis in hamsters
-
Loury D, Embree JR, Steinberg DA, Sonis ST, Fiddes JC (1999) Effect of local application of the antimicrobial peptide IB-367 on the incidence and severity of oral mucositis in hamsters. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 87:544-551
-
(1999)
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
, vol.87
, pp. 544-551
-
-
Loury, D.1
Embree, J.R.2
Steinberg, D.A.3
Sonis, S.T.4
Fiddes, J.C.5
-
128
-
-
0033948397
-
IB-367, a protegrin peptide with in vitro and in vivo activities against the microflora associated with oral mucositis
-
Mosca DA, Hurst MA, So W, Viajar BS, Fujii CA, Falla TJ (2000) IB-367, a protegrin peptide with in vitro and in vivo activities against the microflora associated with oral mucositis. Antimicrob Agents Chemother 44:1803-1808
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 1803-1808
-
-
Mosca, D.A.1
Hurst, M.A.2
So, W.3
Viajar, B.S.4
Fujii, C.A.5
Falla, T.J.6
|