TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass

Diabetologia

Volumn 57, Issue 3, 2014, Pages 542-553

  Takamoto, Iseki ^a,b,c   Kubota, Naoto ^a,b,c,d   Nakaya, Keizo ^a   Kumagai, Katsuyoshi ^a,e   Hashimoto, Shinji ^a   Kubota, Tetsuya ^a,c,d,f   Inoue, Mariko ^a,c   Kajiwara, Eiji ^a   Katsuyama, Hisayuki ^a   Obata, Atsushi ^a   Sakurai, Yoshitaka ^a   Iwamoto, Masahiko ^a   Kitamura, Tadahiro ^g   Ueki, Kohjiro ^a,b   Kadowaki, Takashi ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL INSTITUTE OF HEALTH AND NUTRITION   (Japan)

^d RIKEN Center for Integrative Medical Sciences   (Japan)

^e TOKYO MEDICAL UNIVERSITY   (Japan)

^f TOHO UNIVERSITY OHASHI MEDICAL CENTER   (Japan)

^g GUNMA UNIVERSITY   (Japan)

Author keywords

Beta cell proliferation; Dominant negative form; Insulin production; Insulin secretion; TCF7L2; Wnt catenin signalling

Indexed keywords

GLUCOSE; INSULIN; T CELL FACTOR PROTEIN; TCF7L2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR 7 LIKE 2;

ANIMAL; CELL CULTURE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; HOMEOSTASIS; METABOLISM; MOUSE; PANCREAS; PANCREAS ISLET; PANCREAS ISLET BETA CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION (PROCESS); WESTERN BLOTTING; WNT SIGNALING PATHWAY;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; GENE EXPRESSION REGULATION; GLUCOSE; HOMEOSTASIS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MICE; PANCREAS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TCF TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR 7-LIKE 2 PROTEIN; WNT SIGNALING PATHWAY;

EID: 84894538334     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-3131-6     Document Type: Article

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