Foxo1 gain of function in the pancreas causes glucose intolerance, polycystic pancreas, and islet hypervascularization

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Kikuchi, Osamu ^a   Kobayashi, Masaki ^a   Amano, Kosuke ^a   Sasaki, Tsutomu ^a   Kitazumi, Tomoya ^a   Kim, Hye Jin ^a   Lee, Yong Soo ^a   Yokota Hashimoto, Hiromi ^a   Kitamura, Yukari Ido ^a   Kitamura, Tadahiro ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PDX 1; VASCULOTROPIN A; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; MAFA PROTEIN, MOUSE; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR MAF;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; EPITHELIUM CELL; FEMALE; GAIN OF FUNCTION MUTATION; GENE OVEREXPRESSION; GLUCOSE INTOLERANCE; IMPAIRED GLUCOSE TOLERANCE; MALE; MOUSE; NONHUMAN; PANCREAS BLOOD FLOW; PANCREAS CYST; PANCREAS DUCT; PANCREAS ISLET BETA CELL; PANCREAS ISLET DISEASE; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE; ANIMAL; CYST; CYTOLOGY; GENETIC TRANSCRIPTION; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; PANCREAS; PANCREAS DISEASE; PANCREAS ISLET; PATHOLOGY; PHYSIOLOGY; VASCULARIZATION;

MUS; MUS MUSCULUS;

ANIMALS; CELL PROLIFERATION; CYSTS; EPITHELIAL CELLS; FORKHEAD TRANSCRIPTION FACTORS; GLUCOSE INTOLERANCE; HOMEODOMAIN PROTEINS; IMMUNOHISTOCHEMISTRY; ISLETS OF LANGERHANS; MAF TRANSCRIPTION FACTORS, LARGE; MICE; MICE, TRANSGENIC; PANCREAS; PANCREATIC DISEASES; PROMOTER REGIONS, GENETIC; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84863127126     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032249     Document Type: Article

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