메뉴 건너뛰기




Volumn 41, Issue 10, 2009, Pages 1068-1075

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; T CELL FACTOR PROTEIN; T CELL FACTOR PROTEIN 3; T CELL FACTOR PROTEIN 4; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 70349554461     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.431     Document Type: Article
Times cited : (173)

References (32)
  • 1
    • 0031937635 scopus 로고    scopus 로고
    • Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse
    • Korinek, V. et al. Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse. Mol. Cell. Biol. 18, 1248-1256 (1998).
    • (1998) Mol. Cell. Biol , vol.18 , pp. 1248-1256
    • Korinek, V.1
  • 2
    • 0035395874 scopus 로고    scopus 로고
    • Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin
    • Merrill, B.J., Gat, U., DasGupta, R. & Fuchs, E. Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin. Genes Dev. 15, 1688-1705 (2001).
    • (2001) Genes Dev , vol.15 , pp. 1688-1705
    • Merrill, B.J.1    Gat, U.2    Dasgupta, R.3    Fuchs, E.4
  • 3
    • 0842344619 scopus 로고    scopus 로고
    • Tcf3: A transcriptional regulator of axis induction in the early embryo
    • Merrill, B.J. et al. Tcf3: a transcriptional regulator of axis induction in the early embryo. Development 131, 263-274 (2004).
    • (2004) Development , vol.131 , pp. 263-274
    • Merrill, B.J.1
  • 4
    • 33749065765 scopus 로고    scopus 로고
    • Tcf3 governs stem cell features and represses cell fate determination in skin
    • Nguyen, H., Rendl, M. & Fuchs, E. Tcf3 governs stem cell features and represses cell fate determination in skin. Cell 127, 171-183 (2006).
    • (2006) Cell , vol.127 , pp. 171-183
    • Nguyen, H.1    Rendl, M.2    Fuchs, E.3
  • 5
    • 0032718124 scopus 로고    scopus 로고
    • Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
    • DasGupta, R. & Fuchs, E. Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development 126, 4557-4568 (1999).
    • (1999) Development , vol.126 , pp. 4557-4568
    • Dasgupta, R.1    Fuchs, E.2
  • 6
    • 48649085299 scopus 로고    scopus 로고
    • Hair follicle stem cells are specifed and function in early skin morphogenesis
    • Nowak, J.A., Polak, L., Pasolli, H.A. & Fuchs, E. Hair follicle stem cells are specifed and function in early skin morphogenesis. Cell Stem Cell 3, 33-43 (2008).
    • (2008) Cell Stem Cell , vol.3 , pp. 33-43
    • Nowak, J.A.1    Polak, L.2    Pasolli, H.A.3    Fuchs, E.4
  • 7
    • 0035951372 scopus 로고    scopus 로고
    • Morphogenesis and renewal of hair follicles from adult multipotent stem cells
    • Oshima, H., Rochat, A., Kedzia, C., Kobayashi, K. & Barrandon, Y. Morphogenesis and renewal of hair follicles from adult multipotent stem cells. Cell 104, 233-245 (2001).
    • (2001) Cell , vol.104 , pp. 233-245
    • Oshima, H.1    Rochat, A.2    Kedzia, C.3    Kobayashi, K.4    Barrandon, Y.5
  • 8
    • 23944464036 scopus 로고    scopus 로고
    • Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle
    • Alonso, L. et al. Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle. J. Cell Biol. 170, 559-570 (2005).
    • (2005) J. Cell Biol , vol.170 , pp. 559-570
    • Alonso, L.1
  • 9
    • 22344441322 scopus 로고    scopus 로고
    • Defning the impact of beta-catenin/Tcf transactivation on epithelial stem cells
    • Lowry, W.E. et al. Defning the impact of beta-catenin/Tcf transactivation on epithelial stem cells. Genes Dev. 19, 1596-1611 (2005).
    • (2005) Genes Dev , vol.19 , pp. 1596-1611
    • Lowry, W.E.1
  • 10
    • 0036023356 scopus 로고    scopus 로고
    • Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours
    • Niemann, C., Owens, D.M., Hulsken, J., Birchmeier, W. & Watt, F.M. Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development 129, 95-109 (2002).
    • (2002) Development , vol.129 , pp. 95-109
    • Niemann, C.1    Owens, D.M.2    Hulsken, J.3    Birchmeier, W.4    Watt, F.M.5
  • 11
    • 0032567078 scopus 로고    scopus 로고
    • De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated β-catenin in skin
    • Gat, U., DasGupta, R., Degenstein, L. & Fuchs, E. De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated β-catenin in skin. Cell 95, 605-614 (1998).
    • (1998) Cell , vol.95 , pp. 605-614
    • Gat, U.1    Dasgupta, R.2    Degenstein, L.3    Fuchs, E.4
  • 12
    • 0038625113 scopus 로고    scopus 로고
    • Transient activation of beta-catenin signaling in cutaneous keratinocytes is suffcient to trigger the active growth phase of the hair cycle in mice
    • Van Mater, D., Kolligs, F.T., Dlugosz, A.A. & Fearon, E.R. Transient activation of beta-catenin signaling in cutaneous keratinocytes is suffcient to trigger the active growth phase of the hair cycle in mice. Genes Dev. 17, 1219-1224 (2003).
    • (2003) Genes Dev , vol.17 , pp. 1219-1224
    • Van Mater, D.1    Kolligs, F.T.2    Dlugosz, A.A.3    Fearon, E.R.4
  • 13
    • 2342427631 scopus 로고    scopus 로고
    • Transient activation of beta-catenin signalling in adult mouse epidermis is suffcient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours
    • Lo Celso, C., Prowse, D.M. & Watt, F.M. Transient activation of beta-catenin signalling in adult mouse epidermis is suffcient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours. Development 131, 1787-1799 (2004).
    • (2004) Development , vol.131 , pp. 1787-1799
    • Lo Celso, C.1    Prowse, D.M.2    Watt, F.M.3
  • 14
    • 34249106502 scopus 로고    scopus 로고
    • Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding
    • Ito, M. et al. Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding. Nature 447, 316-320 (2007).
    • (2007) Nature , vol.447 , pp. 316-320
    • Ito, M.1
  • 15
    • 0035907041 scopus 로고    scopus 로고
    • β-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
    • Huelsken, J., Vogel, R., Erdmann, B., Cotsarelis, G. & Birchmeier, W. β-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 105, 533-545 (2001).
    • (2001) Cell , vol.105 , pp. 533-545
    • Huelsken, J.1    Vogel, R.2    Erdmann, B.3    Cotsarelis, G.4    Birchmeier, W.5
  • 16
    • 41649089525 scopus 로고    scopus 로고
    • Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling
    • Malanchi, I. et al. Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling. Nature 452, 650-653 (2008).
    • (2008) Nature , vol.452 , pp. 650-653
    • Malanchi, I.1
  • 17
    • 0033587776 scopus 로고    scopus 로고
    • The magical touch: Genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin
    • Vasioukhin, V., Degenstein, L., Wise, B. & Fuchs, E. The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin. Proc. Natl. Acad. Sci. USA 96, 8551-8556 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 8551-8556
    • Vasioukhin, V.1    Degenstein, L.2    Wise, B.3    Fuchs, E.4
  • 18
    • 27844547641 scopus 로고    scopus 로고
    • Molecular dissection of mesenchymal-epithelial interactions in the hair follicle
    • Rendl, M., Lewis, L. & Fuchs, E. Molecular dissection of mesenchymal-epithelial interactions in the hair follicle. PLoS Biol. 3, e331 (2005).
    • (2005) PLoS Biol , vol.3
    • Rendl, M.1    Lewis, L.2    Fuchs, E.3
  • 19
    • 0031848068 scopus 로고    scopus 로고
    • Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
    • Korinek, V. et al. Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat. Genet. 19, 379-383 (1998).
    • (1998) Nat. Genet , vol.19 , pp. 379-383
    • Korinek, V.1
  • 20
    • 41149174852 scopus 로고    scopus 로고
    • Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells
    • Cole, M.F., Johnstone, S.E., Newman, J.J., Kagey, M.H. & Young, R.A. Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells. Genes Dev. 22, 746-755 (2008).
    • (2008) Genes Dev , vol.22 , pp. 746-755
    • Cole, M.F.1    Johnstone, S.E.2    Newman, J.J.3    Kagey, M.H.4    Young, R.A.5
  • 21
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • DOI 10.1038/nature03319
    • Reya, T. & Clevers, H. Wnt signalling in stem cells and cancer. Nature 434, 843-850 (2005). (Pubitemid 40558990)
    • (2005) Nature , vol.434 , Issue.7035 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 22
    • 23244452254 scopus 로고    scopus 로고
    • Notch1 is essential for postnatal hair follicle development and homeostasis
    • Vauclair, S., Nicolas, M., Barrandon, Y. & Radtke, F. Notch1 is essential for postnatal hair follicle development and homeostasis. Dev. Biol. 284, 184-193 (2005).
    • (2005) Dev. Biol , vol.284 , pp. 184-193
    • Vauclair, S.1    Nicolas, M.2    Barrandon, Y.3    Radtke, F.4
  • 23
    • 39749178390 scopus 로고    scopus 로고
    • Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo
    • Fleming, H.E. et al. Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell 2, 274-283 (2008).
    • (2008) Cell Stem Cell , vol.2 , pp. 274-283
    • Fleming, H.E.1
  • 24
    • 34447343780 scopus 로고    scopus 로고
    • Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells
    • Ye, X. et al. Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells. Mol. Cell 27, 183-196 (2007).
    • (2007) Mol. Cell , vol.27 , pp. 183-196
    • Ye, X.1
  • 25
    • 29244446792 scopus 로고    scopus 로고
    • Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT
    • Almeida, M., Han, L., Bellido, T., Manolagas, S.C. & Kousteni, S. Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT. J. Biol. Chem. 280, 41342-41351 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 41342-41351
    • Almeida, M.1    Han, L.2    Bellido, T.3    Manolagas, S.C.4    Kousteni, S.5
  • 26
    • 11244320393 scopus 로고    scopus 로고
    • FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK
    • Essers, M.A.G. et al. FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK. EMBO J. 23, 4802-4812 (2004).
    • (2004) EMBO J , vol.23 , pp. 4802-4812
    • Essers, M.A.G.1
  • 27
    • 34547924424 scopus 로고    scopus 로고
    • Increased Wnt signaling during aging alters muscle stem cell fate and increases fbrosis
    • Brack, A.S. et al. Increased Wnt signaling during aging alters muscle stem cell fate and increases fbrosis. Science 317, 807-810 (2007).
    • (2007) Science , vol.317 , pp. 807-810
    • Brack, A.S.1
  • 28
    • 34547908461 scopus 로고    scopus 로고
    • Augmented Wnt signaling in a mammalian model of accelerated aging
    • Liu, H. et al. Augmented Wnt signaling in a mammalian model of accelerated aging. Science 317, 803-806 (2007).
    • (2007) Science , vol.317 , pp. 803-806
    • Liu, H.1
  • 29
    • 0027945654 scopus 로고
    • Development of several organs that require inductive epithelial- mesenchymal interactions is impaired in LEF-1-defcient mice
    • van Genderen, C. et al. Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-defcient mice. Genes Dev. 8, 2691-2703 (1994).
    • (1994) Genes Dev , vol.8 , pp. 2691-2703
    • Van Genderen, C.1
  • 30
    • 33846113924 scopus 로고    scopus 로고
    • Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation
    • Liu, T.X. et al. Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation. Nat. Med. 13, 78-83 (2007).
    • (2007) Nat. Med , vol.13 , pp. 78-83
    • Liu, T.X.1
  • 31
    • 0041319629 scopus 로고    scopus 로고
    • GATA-3: An unexpected regulator of cell lineage determination in skin
    • Kaufman, C.K. et al. GATA-3: an unexpected regulator of cell lineage determination in skin. Genes Dev. 17, 2108-2122 (2003).
    • (2003) Genes Dev , vol.17 , pp. 2108-2122
    • Kaufman, C.K.1
  • 32
    • 4444290010 scopus 로고    scopus 로고
    • Multipotency, and the existence of two cell populations within an epithelial stem cell niche
    • Blanpain, C., Lowry, W.E., Geoghegan, A., Polak, L. & Fuchs, E. Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 118, 635-648 (2004)
    • (2004) Cell , vol.118 , pp. 635-648
    • Blanpain, C.1    Lowry, W.E.2    Geoghegan, A.3    Polak, L.4    Self-Renewal, F.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.