Comparison of self-microemulsifying drug delivery system versus solid dispersion technology used in the improvement of dissolution rate and bioavailability of vinpocetine

Yaoxue Xuebao

Volumn 44, Issue 6, 2009, Pages 658-666

  Chen, Ying ^a,b   Li, Gao ^b   Huang, Jian Geng ^b   Wang, Rui Hua ^b   Liu, Hong ^a   Tang, Ren ^a  

^a WUHAN GENERAL HOSPITAL OF GUANGZHOU COMMAND   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Bioavailability; Caco 2; Dissolution in vitro; Self microemulsifying drug delivery system; Solid dispersion; Vinpocetine

Indexed keywords

CREMOPHOR; DIETHYLENE GLYCOL MONOETHYL ETHER; GUM ARABIC; OLEIC ACID; POLOXAMER; VINPOCETINE;

ARTICLE; BIOEQUIVALENCE; CELL JUNCTION; CONTROLLED STUDY; DISSOLUTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; DRUG UPTAKE; FOOD INTAKE; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; INTESTINE MUCOSA PERMEABILITY; PEYER PATCH; SELF MICROEMULSIFYING DRUG DELIVERY SYTEM; SOLID DISPERSION TECHNOLOGY;

ANIMALS; BIOLOGICAL AVAILABILITY; CACO-2 CELLS; DOSAGE FORMS; DRUG DELIVERY SYSTEMS; EMULSIONS; HUMANS; MALE; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; VINCA ALKALOIDS;

EID: 68549115394     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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