-
1
-
-
0343671487
-
Characterization and measurement of dehydroepiandrosterone sulfate in rat brain
-
1:CAS:528:DyaL3MXlsVyitLY%3D 10.1073/pnas.78.8.4704 6458035
-
Corpechot C, Robel P, Axelson M, Sjovall J, Baulieu EE (1981) Characterization and measurement of dehydroepiandrosterone sulfate in rat brain. Proc Natl Acad Sci USA 78(8):4704-4707
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, Issue.8
, pp. 4704-4707
-
-
Corpechot, C.1
Robel, P.2
Axelson, M.3
Sjovall, J.4
Baulieu, E.E.5
-
2
-
-
47849086131
-
Estrogen synthesis in the brain - Role in synaptic plasticity and memory
-
1:CAS:528:DC%2BD1cXpsValt7s%3D 10.1016/j.mce.2008.04.017 18541362
-
Hojo Y, Murakami G, Mukai H, Higo S, Hatanaka Y, Ogiue-Ikeda M, Ishii H, Kimoto T, Kawato S (2008) Estrogen synthesis in the brain - role in synaptic plasticity and memory. Mol Cell Endocrinol 290(1-2):31-43
-
(2008)
Mol Cell Endocrinol
, vol.290
, Issue.1-2
, pp. 31-43
-
-
Hojo, Y.1
Murakami, G.2
Mukai, H.3
Higo, S.4
Hatanaka, Y.5
Ogiue-Ikeda, M.6
Ishii, H.7
Kimoto, T.8
Kawato, S.9
-
3
-
-
80053482654
-
Short-term hormone therapy with transdermal estradiol improves cognition for postmenopausal women with Alzheimer's disease: Results of a randomized controlled trial
-
1:CAS:528:DC%2BC3MXhtF2jtrvK 3302351 21694454
-
Wharton W, Baker LD, Gleason CE, Dowling M, Barnet JH, Johnson S, Carlsson C, Craft S, Asthana S (2011) Short-term hormone therapy with transdermal estradiol improves cognition for postmenopausal women with Alzheimer's disease: results of a randomized controlled trial. J Alzheimers Dis 26(3):495-505
-
(2011)
J Alzheimers Dis
, vol.26
, Issue.3
, pp. 495-505
-
-
Wharton, W.1
Baker, L.D.2
Gleason, C.E.3
Dowling, M.4
Barnet, J.H.5
Johnson, S.6
Carlsson, C.7
Craft, S.8
Asthana, S.9
-
4
-
-
84862844614
-
Emerging roles of the ubiquitin-proteasome system in the steroid receptor signaling
-
1:CAS:528:DC%2BC38XltVKmt7Y%3D 10.1007/s12272-012-0301-x 22477185
-
Lee JH, Lee MJ (2012) Emerging roles of the ubiquitin-proteasome system in the steroid receptor signaling. Arch Pharm Res 35(3):397-407
-
(2012)
Arch Pharm Res
, vol.35
, Issue.3
, pp. 397-407
-
-
Lee, J.H.1
Lee, M.J.2
-
5
-
-
14844343093
-
A transmembrane intracellular estrogen receptor mediates rapid cell signaling
-
1:CAS:528:DC%2BD2MXitV2is7c%3D 10.1126/science.1106943 15705806
-
Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER (2005) A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 307(5715):1625-1630
-
(2005)
Science
, vol.307
, Issue.5715
, pp. 1625-1630
-
-
Revankar, C.M.1
Cimino, D.F.2
Sklar, L.A.3
Arterburn, J.B.4
Prossnitz, E.R.5
-
6
-
-
84868137482
-
Psychosocial factors that shape patient and carer experiences of dementia diagnosis and treatment: A systematic review of qualitative studies
-
10.1371/journal.pmed.1001331 3484131 23118618
-
Bunn F, Goodman C, Sworn K, Rait G, Brayne C, Robinson L, McNeilly E, Iliffe S (2012) Psychosocial factors that shape patient and carer experiences of dementia diagnosis and treatment: a systematic review of qualitative studies. PLoS Med 9(10):e1001331
-
(2012)
PLoS Med
, vol.9
, Issue.10
, pp. 1001331
-
-
Bunn, F.1
Goodman, C.2
Sworn, K.3
Rait, G.4
Brayne, C.5
Robinson, L.6
McNeilly, E.7
Iliffe, S.8
-
7
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
1:CAS:528:DC%2BD3MXislCrsLc%3D 11274343
-
Selkoe DJ (2001) Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 81(2):741-766
-
(2001)
Physiol Rev
, vol.81
, Issue.2
, pp. 741-766
-
-
Selkoe, D.J.1
-
8
-
-
77954558825
-
Alzheimer's disease therapeutic research: The path forward
-
10.1186/alzrt2 2719107 19674435
-
Aisen PS (2009) Alzheimer's disease therapeutic research: the path forward. Alzheimers Res Ther 1(1):2
-
(2009)
Alzheimers Res Ther
, vol.1
, Issue.1
, pp. 2
-
-
Aisen, P.S.1
-
9
-
-
84878114130
-
Tau degradation: The ubiquitin-proteasome system versus the autophagy-lysosome system
-
1:CAS:528:DC%2BC3sXlvVCrt7s%3D 10.1016/j.pneurobio.2013.03.001 23528736
-
Lee MJ, Lee JH, Rubinsztein DC (2013) Tau degradation: the ubiquitin-proteasome system versus the autophagy-lysosome system. Prog Neurobiol 105(2013):49-59
-
(2013)
Prog Neurobiol
, vol.105
, Issue.2013
, pp. 49-59
-
-
Lee, M.J.1
Lee, J.H.2
Rubinsztein, D.C.3
-
10
-
-
0038708285
-
Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease
-
1:STN:280:DC%2BD3s3it1Sqtg%3D%3D 10.1212/01.WNL.0000063311.58879.01 12743238
-
Giannakopoulos P, Herrmann FR, Bussiere T, Bouras C, Kovari E, Perl DP, Morrison JH, Gold G, Hof PR (2003) Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease. Neurology 60(9):1495-1500
-
(2003)
Neurology
, vol.60
, Issue.9
, pp. 1495-1500
-
-
Giannakopoulos, P.1
Herrmann, F.R.2
Bussiere, T.3
Bouras, C.4
Kovari, E.5
Perl, D.P.6
Morrison, J.H.7
Gold, G.8
Hof, P.R.9
-
11
-
-
8644260921
-
Selective oestrogen receptor modulators/new antioestrogens: A clinical perspective
-
1:CAS:528:DC%2BD2cXpslWntLs%3D 10.1016/j.ctrv.2004.04.003 15541579
-
Robertson JF (2004) Selective oestrogen receptor modulators/new antioestrogens: a clinical perspective. Cancer Treat Rev 30(8):695-706
-
(2004)
Cancer Treat Rev
, vol.30
, Issue.8
, pp. 695-706
-
-
Robertson, J.F.1
-
12
-
-
0033781929
-
Raloxifene: A selective estrogen receptor modulator (SERM) with multiple target system effects
-
1:CAS:528:DC%2BD3cXnslChsbg%3D 10.1634/theoncologist.5-5-388 11040275
-
Muchmore DB (2000) Raloxifene: a selective estrogen receptor modulator (SERM) with multiple target system effects. Oncologist 5(5):388-392
-
(2000)
Oncologist
, vol.5
, Issue.5
, pp. 388-392
-
-
Muchmore, D.B.1
-
13
-
-
0030925683
-
Steroid receptor interactions with heat shock protein and immunophilin chaperones
-
1:CAS:528:DyaK2sXktV2qsrs%3D 9183567
-
Pratt WB, Toft DO (1997) Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocr Rev 18(3):306-360
-
(1997)
Endocr Rev
, vol.18
, Issue.3
, pp. 306-360
-
-
Pratt, W.B.1
Toft, D.O.2
-
14
-
-
8844262660
-
Principles for modulation of the nuclear receptor superfamily
-
1:CAS:528:DC%2BD2cXptFemtrY%3D 10.1038/nrd1551 15520817
-
Gronemeyer H, Gustafsson JA, Laudet V (2004) Principles for modulation of the nuclear receptor superfamily. Nat Rev Drug Discov 3(11):950-964
-
(2004)
Nat Rev Drug Discov
, vol.3
, Issue.11
, pp. 950-964
-
-
Gronemeyer, H.1
Gustafsson, J.A.2
Laudet, V.3
-
15
-
-
25444455856
-
Dynamic combinatorial networks in nuclear receptor-mediated transcription
-
1:CAS:528:DC%2BD2MXhtVWitbfL 10.1074/jbc.R500008200 16076839
-
Rochette-Egly C (2005) Dynamic combinatorial networks in nuclear receptor-mediated transcription. J Biol Chem 280(38):32565-32568
-
(2005)
J Biol Chem
, vol.280
, Issue.38
, pp. 32565-32568
-
-
Rochette-Egly, C.1
-
16
-
-
33746600263
-
Estrogen receptor target gene: An evolving concept
-
1:CAS:528:DC%2BD28XnvFajsrg%3D 10.1210/me.2005-0334 16396959
-
Carroll JS, Brown M (2006) Estrogen receptor target gene: an evolving concept. Mol Endocrinol 20(8):1707-1714
-
(2006)
Mol Endocrinol
, vol.20
, Issue.8
, pp. 1707-1714
-
-
Carroll, J.S.1
Brown, M.2
-
17
-
-
78650555076
-
Estrogen-induced reactive oxygen species-mediated signalings contribute to breast cancer
-
1:CAS:528:DC%2BC3MXhtF2mtQ%3D%3D 21036202
-
Okoh V, Deoraj A, Roy D (2011) Estrogen-induced reactive oxygen species-mediated signalings contribute to breast cancer. Biochim Biophys Acta 1815(1):115-133
-
(2011)
Biochim Biophys Acta
, vol.1815
, Issue.1
, pp. 115-133
-
-
Okoh, V.1
Deoraj, A.2
Roy, D.3
-
18
-
-
15444368857
-
Mechanisms of estrogen receptor signaling: Convergence of genomic and nongenomic actions on target genes
-
10.1210/me.2004-0486 15695368
-
Bjornstrom L, Sjoberg M (2005) Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes. Mol Endocrinol 19(4):833-842
-
(2005)
Mol Endocrinol
, vol.19
, Issue.4
, pp. 833-842
-
-
Bjornstrom, L.1
Sjoberg, M.2
-
19
-
-
0036140032
-
Estrogen action via the G protein-coupled receptor, GPR30: Stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis
-
1:CAS:528:DC%2BD38XhvVCitQ%3D%3D 10.1210/mend.16.1.0758 11773440
-
Filardo EJ, Quinn JA, Frackelton AR Jr, Bland KI (2002) Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Mol Endocrinol 16(1):70-84
-
(2002)
Mol Endocrinol
, vol.16
, Issue.1
, pp. 70-84
-
-
Filardo, E.J.1
Quinn, J.A.2
Frackelton, Jr.A.R.3
Bland, K.I.4
-
20
-
-
75749118309
-
A new membrane G protein-coupled receptor (GPR30) is involved in the cardiac effects of 17beta-estradiol in the male rat
-
1:CAS:528:DC%2BC3cXht1Wisb4%3D 20065491
-
Filice E, Recchia AG, Pellegrino D, Angelone T, Maggiolini M, Cerra MC (2009) A new membrane G protein-coupled receptor (GPR30) is involved in the cardiac effects of 17beta-estradiol in the male rat. J Physiol Pharmacol 60(4):3-10
-
(2009)
J Physiol Pharmacol
, vol.60
, Issue.4
, pp. 3-10
-
-
Filice, E.1
Recchia, A.G.2
Pellegrino, D.3
Angelone, T.4
Maggiolini, M.5
Cerra, M.C.6
-
21
-
-
0033780783
-
Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF
-
1:CAS:528:DC%2BD3cXntVaksLk%3D 10.1210/mend.14.10.0532 11043579
-
Filardo EJ, Quinn JA, Bland KI, Frackelton AR Jr (2000) Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Mol Endocrinol 14(10):1649-1660
-
(2000)
Mol Endocrinol
, vol.14
, Issue.10
, pp. 1649-1660
-
-
Filardo, E.J.1
Quinn, J.A.2
Bland, K.I.3
Frackelton, Jr.A.R.4
-
22
-
-
12344307170
-
Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
-
1:CAS:528:DC%2BD2MXotlWitw%3D%3D 10.1210/en.2004-1064 15539556
-
Thomas P, Pang Y, Filardo EJ, Dong J (2005) Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 146(2):624-632
-
(2005)
Endocrinology
, vol.146
, Issue.2
, pp. 624-632
-
-
Thomas, P.1
Pang, Y.2
Filardo, E.J.3
Dong, J.4
-
23
-
-
0034105457
-
Rapid non-genomic activation of cytosolic cyclic AMP-dependent protein kinase activity and [Ca(2+)](i) by 17beta-oestradiol in female rat distal colon
-
1:CAS:528:DC%2BD3cXisVyltrg%3D 10.1038/sj.bjp.0703193 10742293
-
Doolan CM, Condliffe SB, Harvey BJ (2000) Rapid non-genomic activation of cytosolic cyclic AMP-dependent protein kinase activity and [Ca(2+)](i) by 17beta-oestradiol in female rat distal colon. Br J Pharmacol 129(7):1375-1386
-
(2000)
Br J Pharmacol
, vol.129
, Issue.7
, pp. 1375-1386
-
-
Doolan, C.M.1
Condliffe, S.B.2
Harvey, B.J.3
-
24
-
-
41549115929
-
Non-genomic actions of estrogens and their interaction with genomic actions in the brain
-
1:CAS:528:DC%2BD1cXksVeitbY%3D 10.1016/j.yfrne.2007.08.003 18083219
-
Vasudevan N, Pfaff DW (2008) Non-genomic actions of estrogens and their interaction with genomic actions in the brain. Front Neuroendocrinol 29(2):238-257
-
(2008)
Front Neuroendocrinol
, vol.29
, Issue.2
, pp. 238-257
-
-
Vasudevan, N.1
Pfaff, D.W.2
-
25
-
-
3242682466
-
The biphasic relationship between regional brain senile plaque and neurofibrillary tangle distributions: Modification by age, sex, and APOE polymorphism
-
1:CAS:528:DC%2BD2cXms12gt70%3D 10.1196/annals.1297.005 15246987
-
Corder EH, Ghebremedhin E, Taylor MG, Thal DR, Ohm TG, Braak H (2004) The biphasic relationship between regional brain senile plaque and neurofibrillary tangle distributions: modification by age, sex, and APOE polymorphism. Ann N Y Acad Sci 1019:24-28
-
(2004)
Ann N y Acad Sci
, vol.1019
, pp. 24-28
-
-
Corder, E.H.1
Ghebremedhin, E.2
Taylor, M.G.3
Thal, D.R.4
Ohm, T.G.5
Braak, H.6
-
26
-
-
20344371487
-
Sex differences in the clinical manifestations of Alzheimer disease pathology
-
10.1001/archpsyc.62.6.685 15939846
-
Barnes LL, Wilson RS, Bienias JL, Schneider JA, Evans DA, Bennett DA (2005) Sex differences in the clinical manifestations of Alzheimer disease pathology. Arch Gen Psychiatry 62(6):685-691
-
(2005)
Arch Gen Psychiatry
, vol.62
, Issue.6
, pp. 685-691
-
-
Barnes, L.L.1
Wilson, R.S.2
Bienias, J.L.3
Schneider, J.A.4
Evans, D.A.5
Bennett, D.A.6
-
27
-
-
17144409347
-
The effect of aging on the subcellular distribution of estrogen receptor-alpha in the cholinergic neurons of transgenic and wild-type mice
-
10.1111/j.1460-9568.2005.03953.x 15813954
-
Kalesnykas G, Roschier U, Puolivali J, Wang J, Miettinen R (2005) The effect of aging on the subcellular distribution of estrogen receptor-alpha in the cholinergic neurons of transgenic and wild-type mice. Eur J Neurosci 21(5):1437-1442
-
(2005)
Eur J Neurosci
, vol.21
, Issue.5
, pp. 1437-1442
-
-
Kalesnykas, G.1
Roschier, U.2
Puolivali, J.3
Wang, J.4
Miettinen, R.5
-
28
-
-
0033967348
-
Estrogen binding and estrogen receptor characterization (ERalpha and ERbeta) in the cholinergic neurons of the rat basal forebrain
-
1:CAS:528:DC%2BD3cXhtFWqurw%3D 10.1016/S0306-4522(99)00520-5 10683408
-
Shughrue PJ, Scrimo PJ, Merchenthaler I (2000) Estrogen binding and estrogen receptor characterization (ERalpha and ERbeta) in the cholinergic neurons of the rat basal forebrain. Neuroscience 96(1):41-49
-
(2000)
Neuroscience
, vol.96
, Issue.1
, pp. 41-49
-
-
Shughrue, P.J.1
Scrimo, P.J.2
Merchenthaler, I.3
-
29
-
-
0035239031
-
Neuroprotection by estradiol
-
1:CAS:528:DC%2BD3cXos1Sht7w%3D 10.1016/S0301-0082(00)00025-3 11040417
-
Garcia-Segura LM, Azcoitia I, DonCarlos LL (2001) Neuroprotection by estradiol. Prog Neurobiol 63(1):29-60
-
(2001)
Prog Neurobiol
, vol.63
, Issue.1
, pp. 29-60
-
-
Garcia-Segura, L.M.1
Azcoitia, I.2
Doncarlos, L.L.3
-
30
-
-
0030753755
-
Rapid membrane effects of steroids in neuroblastoma cells: Effects of estrogen on mitogen activated protein kinase signalling cascade and c-fos immediate early gene transcription
-
1:CAS:528:DyaK2sXlsFeisbk%3D 10.1210/endo.138.9.5489 9275096
-
Watters JJ, Campbell JS, Cunningham MJ, Krebs EG, Dorsa DM (1997) Rapid membrane effects of steroids in neuroblastoma cells: effects of estrogen on mitogen activated protein kinase signalling cascade and c-fos immediate early gene transcription. Endocrinology 138(9):4030-4033
-
(1997)
Endocrinology
, vol.138
, Issue.9
, pp. 4030-4033
-
-
Watters, J.J.1
Campbell, J.S.2
Cunningham, M.J.3
Krebs, E.G.4
Dorsa, D.M.5
-
31
-
-
0034969952
-
Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex
-
1:CAS:528:DC%2BD3MXksFCmt7g%3D 10.1385/ENDO:14:3:407 11444439
-
Singh M (2001) Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex. Endocrine 14(3):407-415
-
(2001)
Endocrine
, vol.14
, Issue.3
, pp. 407-415
-
-
Singh, M.1
-
32
-
-
0033118665
-
The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons
-
1:CAS:528:DyaK1MXitFShsbc%3D 10087060
-
Singer CA, Figueroa-Masot XA, Batchelor RH, Dorsa DM (1999) The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons. J Neurosci 19(7):2455-2463
-
(1999)
J Neurosci
, vol.19
, Issue.7
, pp. 2455-2463
-
-
Singer, C.A.1
Figueroa-Masot, X.A.2
Batchelor, R.H.3
Dorsa, D.M.4
-
33
-
-
0037345781
-
Estrogen activates protein kinase C in neurons: Role in neuroprotection
-
1:CAS:528:DC%2BD3sXisVaqu7c%3D 10.1046/j.1471-4159.2003.01631.x 12614334
-
Cordey M, Gundimeda U, Gopalakrishna R, Pike CJ (2003) Estrogen activates protein kinase C in neurons: role in neuroprotection. J Neurochem 84(6):1340-1348
-
(2003)
J Neurochem
, vol.84
, Issue.6
, pp. 1340-1348
-
-
Cordey, M.1
Gundimeda, U.2
Gopalakrishna, R.3
Pike, C.J.4
-
34
-
-
33847032137
-
Estrogen regulates Bcl-w and Bim expression: Role in protection against beta-amyloid peptide-induced neuronal death
-
1:CAS:528:DC%2BD2sXhvFCrurY%3D 10.1523/JNEUROSCI.2382-06.2007 17287517
-
Yao M, Nguyen TV, Pike CJ (2007) Estrogen regulates Bcl-w and Bim expression: role in protection against beta-amyloid peptide-induced neuronal death. J Neurosci 27(6):1422-1433
-
(2007)
J Neurosci
, vol.27
, Issue.6
, pp. 1422-1433
-
-
Yao, M.1
Nguyen, T.V.2
Pike, C.J.3
-
35
-
-
0032997908
-
Estrogen modulates neuronal Bcl-xL expression and beta-amyloid-induced apoptosis: Relevance to Alzheimer's disease
-
1:CAS:528:DyaK1MXitFCksLY%3D 10.1046/j.1471-4159.1999.721552.x 10098861
-
Pike CJ (1999) Estrogen modulates neuronal Bcl-xL expression and beta-amyloid-induced apoptosis: relevance to Alzheimer's disease. J Neurochem 72(4):1552-1563
-
(1999)
J Neurochem
, vol.72
, Issue.4
, pp. 1552-1563
-
-
Pike, C.J.1
-
36
-
-
0033621779
-
Protective action of 17beta-estradiol and tamoxifen on glutamate toxicity in glial cells
-
1:CAS:528:DC%2BD3cXivVSrtr8%3D 10.1016/S0736-5748(99)00097-0 10715583
-
Shy H, Malaiyandi L, Timiras PS (2000) Protective action of 17beta-estradiol and tamoxifen on glutamate toxicity in glial cells. Int J Dev Neurosci 18(2-3):289-297
-
(2000)
Int J Dev Neurosci
, vol.18
, Issue.2-3
, pp. 289-297
-
-
Shy, H.1
Malaiyandi, L.2
Timiras, P.S.3
-
37
-
-
84870195486
-
Dual effect of 17beta-estradiol on NMDA-induced neuronal death: Involvement of metabotropic glutamate receptor 1
-
1:CAS:528:DC%2BC38XhvVahtbjE 10.1210/en.2012-1799 23077075
-
Spampinato SF, Merlo S, Molinaro G, Battaglia G, Bruno V, Nicoletti F, Sortino MA (2012) Dual effect of 17beta-estradiol on NMDA-induced neuronal death: involvement of metabotropic glutamate receptor 1. Endocrinology 153(12):5940-5948
-
(2012)
Endocrinology
, vol.153
, Issue.12
, pp. 5940-5948
-
-
Spampinato, S.F.1
Merlo, S.2
Molinaro, G.3
Battaglia, G.4
Bruno, V.5
Nicoletti, F.6
Sortino, M.A.7
-
38
-
-
36849045250
-
Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice
-
1:CAS:528:DC%2BD2sXhsVeku7bF 10.1523/JNEUROSCI.2718-07.2007 18045930
-
Carroll JC, Rosario ER, Chang L, Stanczyk FZ, Oddo S, LaFerla FM, Pike CJ (2007) Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice. J Neurosci 27(48):13357-13365
-
(2007)
J Neurosci
, vol.27
, Issue.48
, pp. 13357-13365
-
-
Carroll, J.C.1
Rosario, E.R.2
Chang, L.3
Stanczyk, F.Z.4
Oddo, S.5
Laferla, F.M.6
Pike, C.J.7
-
39
-
-
50449091825
-
Seladin-1 is a fundamental mediator of the neuroprotective effects of estrogen in human neuroblast long-term cell cultures
-
1:CAS:528:DC%2BD1cXhtVKnurfI 10.1210/en.2007-1795 18499757
-
Luciani P, Deledda C, Rosati F, Benvenuti S, Cellai I, Dichiara F, Morello M, Vannelli GB, Danza G, Serio M, Peri A (2008) Seladin-1 is a fundamental mediator of the neuroprotective effects of estrogen in human neuroblast long-term cell cultures. Endocrinology 149(9):4256-4266
-
(2008)
Endocrinology
, vol.149
, Issue.9
, pp. 4256-4266
-
-
Luciani, P.1
Deledda, C.2
Rosati, F.3
Benvenuti, S.4
Cellai, I.5
Dichiara, F.6
Morello, M.7
Vannelli, G.B.8
Danza, G.9
Serio, M.10
Peri, A.11
-
40
-
-
30044438885
-
Brain estrogen deficiency accelerates Abeta plaque formation in an Alzheimer's disease animal model
-
1:CAS:528:DC%2BD28XivV2ntQ%3D%3D 10.1073/pnas.0505203102 16365303
-
Yue X, Lu M, Lancaster T, Cao P, Honda S, Staufenbiel M, Harada N, Zhong Z, Shen Y, Li R (2005) Brain estrogen deficiency accelerates Abeta plaque formation in an Alzheimer's disease animal model. Proc Natl Acad Sci USA 102(52):19198-19203
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.52
, pp. 19198-19203
-
-
Yue, X.1
Lu, M.2
Lancaster, T.3
Cao, P.4
Honda, S.5
Staufenbiel, M.6
Harada, N.7
Zhong, Z.8
Shen, Y.9
Li, R.10
-
41
-
-
1342288028
-
An ICI 182,780-sensitive, membrane-related estrogen receptor contributes to estrogenic neuroprotective actions against amyloid-beta toxicity
-
1:CAS:528:DC%2BD2cXisFCgsrs%3D 10.1196/annals.1286.011 14993045
-
Marin R, Guerra B, Morales A, Diaz M, Alonso R (2003) An ICI 182,780-sensitive, membrane-related estrogen receptor contributes to estrogenic neuroprotective actions against amyloid-beta toxicity. Ann N Y Acad Sci 1007:108-116
-
(2003)
Ann N y Acad Sci
, vol.1007
, pp. 108-116
-
-
Marin, R.1
Guerra, B.2
Morales, A.3
Diaz, M.4
Alonso, R.5
-
42
-
-
0036320770
-
Estrogen-mediated neuroprotection against beta-amyloid toxicity requires expression of estrogen receptor alpha or beta and activation of the MAPK pathway
-
1:CAS:528:DC%2BD38Xmt1ejsbo%3D 10.1046/j.1471-4159.2002.01000.x 12153491
-
Fitzpatrick JL, Mize AL, Wade CB, Harris JA, Shapiro RA, Dorsa DM (2002) Estrogen-mediated neuroprotection against beta-amyloid toxicity requires expression of estrogen receptor alpha or beta and activation of the MAPK pathway. J Neurochem 82(3):674-682
-
(2002)
J Neurochem
, vol.82
, Issue.3
, pp. 674-682
-
-
Fitzpatrick, J.L.1
Mize, A.L.2
Wade, C.B.3
Harris, J.A.4
Shapiro, R.A.5
Dorsa, D.M.6
-
43
-
-
78149298225
-
Analysis of oestrogen regulation of alpha-, beta- and gamma-secretase gene and protein expression in cultured human neuronal and glial cells
-
10.1159/000282279 20523023
-
Nord LC, Sundqvist J, Andersson E, Fried G (2010) Analysis of oestrogen regulation of alpha-, beta- and gamma-secretase gene and protein expression in cultured human neuronal and glial cells. Neurodegener Dis 7(6):349-364
-
(2010)
Neurodegener Dis
, vol.7
, Issue.6
, pp. 349-364
-
-
Nord, L.C.1
Sundqvist, J.2
Andersson, E.3
Fried, G.4
-
44
-
-
80052640194
-
17beta-Estradiol regulates insulin-degrading enzyme expression via an ERbeta/PI3-K pathway in hippocampus: Relevance to Alzheimer's prevention
-
1:CAS:528:DC%2BC3MXhtFGgtLvM 10.1016/j.neurobiolaging.2009.12.010 2889185 20053478
-
Zhao L, Yao J, Mao Z, Chen S, Wang Y, Brinton RD (2011) 17beta-Estradiol regulates insulin-degrading enzyme expression via an ERbeta/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention. Neurobiol Aging 32(11):1949-1963
-
(2011)
Neurobiol Aging
, vol.32
, Issue.11
, pp. 1949-1963
-
-
Zhao, L.1
Yao, J.2
Mao, Z.3
Chen, S.4
Wang, Y.5
Brinton, R.D.6
-
45
-
-
74049100935
-
Estrogen stimulates degradation of beta-amyloid peptide by up-regulating neprilysin
-
1:CAS:528:DC%2BC3cXkvFKh 10.1074/jbc.M109.051664 19897485
-
Liang K, Yang L, Yin C, Xiao Z, Zhang J, Liu Y, Huang J (2010) Estrogen stimulates degradation of beta-amyloid peptide by up-regulating neprilysin. J Biol Chem 285(2):935-942
-
(2010)
J Biol Chem
, vol.285
, Issue.2
, pp. 935-942
-
-
Liang, K.1
Yang, L.2
Yin, C.3
Xiao, Z.4
Zhang, J.5
Liu, Y.6
Huang, J.7
-
46
-
-
33846911453
-
Suppression of beta-amyloid precursor protein signaling into the nucleus by estrogens mediated through complex formation between the estrogen receptor and Fe65
-
1:CAS:528:DC%2BD2sXit1amsrg%3D 10.1128/MCB.01280-06 1800721 17130235
-
Bao J, Cao C, Zhang X, Jiang F, Nicosia SV, Bai W (2007) Suppression of beta-amyloid precursor protein signaling into the nucleus by estrogens mediated through complex formation between the estrogen receptor and Fe65. Mol Cell Biol 27(4):1321-1333
-
(2007)
Mol Cell Biol
, vol.27
, Issue.4
, pp. 1321-1333
-
-
Bao, J.1
Cao, C.2
Zhang, X.3
Jiang, F.4
Nicosia, S.V.5
Bai, W.6
-
47
-
-
84862806592
-
Ginsenoside Rg1 promotes nonamyloidgenic cleavage of APP via estrogen receptor signaling to MAPK/ERK and PI3K/Akt
-
1:CAS:528:DC%2BC38XjvVWrtLs%3D 10.1016/j.bbagen.2011.12.005 22178929
-
Shi C, Zheng DD, Fang L, Wu F, Kwong WH, Xu J (2012) Ginsenoside Rg1 promotes nonamyloidgenic cleavage of APP via estrogen receptor signaling to MAPK/ERK and PI3K/Akt. Biochim Biophys Acta 1820(4):453-460
-
(2012)
Biochim Biophys Acta
, vol.1820
, Issue.4
, pp. 453-460
-
-
Shi, C.1
Zheng, D.D.2
Fang, L.3
Wu, F.4
Kwong, W.H.5
Xu, J.6
-
48
-
-
0033605607
-
Insulin-degrading enzyme in the Alzheimer's disease brain: Prominent localization in neurons and senile plaques
-
1:CAS:528:DyaK1MXitlKisrc%3D 10.1016/S0304-3940(99)00135-4 10213160
-
Bernstein HG, Ansorge S, Riederer P, Reiser M, Frolich L, Bogerts B (1999) Insulin-degrading enzyme in the Alzheimer's disease brain: prominent localization in neurons and senile plaques. Neurosci Lett 263(2-3):161-164
-
(1999)
Neurosci Lett
, vol.263
, Issue.2-3
, pp. 161-164
-
-
Bernstein, H.G.1
Ansorge, S.2
Riederer, P.3
Reiser, M.4
Frolich, L.5
Bogerts, B.6
-
49
-
-
0035399887
-
Insulin-degrading enzyme: Embarking on amyloid destruction
-
1:CAS:528:DC%2BD3MXkvVegtbY%3D 10.1016/S0968-0004(01)01876-X 11440853
-
Kurochkin IV (2001) Insulin-degrading enzyme: embarking on amyloid destruction. Trends Biochem Sci 26(7):421-425
-
(2001)
Trends Biochem Sci
, vol.26
, Issue.7
, pp. 421-425
-
-
Kurochkin, I.V.1
-
50
-
-
0028176821
-
Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme
-
1:CAS:528:DyaK2cXktlansLY%3D 10.1016/0014-5793(94)00387-4 8194595
-
Kurochkin IV, Goto S (1994) Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme. FEBS Lett 345(1):33-37
-
(1994)
FEBS Lett
, vol.345
, Issue.1
, pp. 33-37
-
-
Kurochkin, I.V.1
Goto, S.2
-
51
-
-
29844432266
-
Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: Review and hypothesis
-
1:CAS:528:DC%2BD28XitFClsg%3D%3D 10.1016/j.neurobiolaging.2005.01.004 16399206
-
Qiu WQ, Folstein MF (2006) Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis. Neurobiol Aging 27(2):190-198
-
(2006)
Neurobiol Aging
, vol.27
, Issue.2
, pp. 190-198
-
-
Qiu, W.Q.1
Folstein, M.F.2
-
52
-
-
84867776138
-
17beta-estradiol and progesterone regulate expression of beta-amyloid clearance factors in primary neuron cultures and female rat brain
-
1:CAS:528:DC%2BC38Xhs1OnsLfO 10.1210/en.2012-1464 22962256
-
Jayaraman A, Carroll JC, Morgan TE, Lin S, Zhao L, Arimoto JM, Murphy MP, Beckett TL, Finch CE, Brinton RD, Pike CJ (2012) 17beta-estradiol and progesterone regulate expression of beta-amyloid clearance factors in primary neuron cultures and female rat brain. Endocrinology 153(11):5467-5479
-
(2012)
Endocrinology
, vol.153
, Issue.11
, pp. 5467-5479
-
-
Jayaraman, A.1
Carroll, J.C.2
Morgan, T.E.3
Lin, S.4
Zhao, L.5
Arimoto, J.M.6
Murphy, M.P.7
Beckett, T.L.8
Finch, C.E.9
Brinton, R.D.10
Pike, C.J.11
-
53
-
-
34547693437
-
Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy
-
1:CAS:528:DC%2BD2sXosValsL4%3D 10.2353/ajpath.2007.070105 17591969
-
Farris W, Schutz SG, Cirrito JR, Shankar GM, Sun X, George A, Leissring MA, Walsh DM, Qiu WQ, Holtzman DM, Selkoe DJ (2007) Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy. Am J Pathol 171(1):241-251
-
(2007)
Am J Pathol
, vol.171
, Issue.1
, pp. 241-251
-
-
Farris, W.1
Schutz, S.G.2
Cirrito, J.R.3
Shankar, G.M.4
Sun, X.5
George, A.6
Leissring, M.A.7
Walsh, D.M.8
Qiu, W.Q.9
Holtzman, D.M.10
Selkoe, D.J.11
-
54
-
-
74149090517
-
Estrogen regulation of the neprilysin gene through a hormone-responsive element
-
1:CAS:528:DC%2BD1MXhtFaksbnE 10.1007/s12031-008-9168-1 19127446
-
Xiao ZM, Sun L, Liu YM, Zhang JJ, Huang J (2009) Estrogen regulation of the neprilysin gene through a hormone-responsive element. J Mol Neurosci 39(1-2):22-26
-
(2009)
J Mol Neurosci
, vol.39
, Issue.1-2
, pp. 22-26
-
-
Xiao, Z.M.1
Sun, L.2
Liu, Y.M.3
Zhang, J.J.4
Huang, J.5
-
55
-
-
33751112725
-
Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism
-
1:CAS:528:DC%2BD28XhtFymsLjM 10.1523/JNEUROSCI.2085-06.2006 17065436
-
Yin KJ, Cirrito JR, Yan P, Hu X, Xiao Q, Pan X, Bateman R, Song H, Hsu FF, Turk J, Xu J, Hsu CY, Mills JC, Holtzman DM, Lee JM (2006) Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism. J Neurosci 26(43):10939-10948
-
(2006)
J Neurosci
, vol.26
, Issue.43
, pp. 10939-10948
-
-
Yin, K.J.1
Cirrito, J.R.2
Yan, P.3
Hu, X.4
Xiao, Q.5
Pan, X.6
Bateman, R.7
Song, H.8
Hsu, F.F.9
Turk, J.10
Xu, J.11
Hsu, C.Y.12
Mills, J.C.13
Holtzman, D.M.14
Lee, J.M.15
-
56
-
-
0032485108
-
17beta-oestradiol enhances release of matrix metalloproteinase-2 from human vascular smooth muscle cells
-
1:CAS:528:DyaK1cXitFKit7w%3D 10.1016/S0925-4439(97)00097-5 9573355
-
Wingrove CS, Garr E, Godsland IF, Stevenson JC (1998) 17beta-oestradiol enhances release of matrix metalloproteinase-2 from human vascular smooth muscle cells. Biochim Biophys Acta 1406(2):169-174
-
(1998)
Biochim Biophys Acta
, vol.1406
, Issue.2
, pp. 169-174
-
-
Wingrove, C.S.1
Garr, E.2
Godsland, I.F.3
Stevenson, J.C.4
-
57
-
-
84858719450
-
Estrogen activates matrix metalloproteinases-2 and -9 to increase beta amyloid degradation
-
1:CAS:528:DC%2BC38XmsVeltbs%3D 10.1016/j.mcn.2012.02.005 22402435
-
Merlo S, Sortino MA (2012) Estrogen activates matrix metalloproteinases-2 and -9 to increase beta amyloid degradation. Mol Cell Neurosci 49(4):423-429
-
(2012)
Mol Cell Neurosci
, vol.49
, Issue.4
, pp. 423-429
-
-
Merlo, S.1
Sortino, M.A.2
-
58
-
-
17044439074
-
Glycogen synthase kinase 3beta links neuroprotection by 17beta-estradiol to key Alzheimer processes
-
1:CAS:528:DC%2BD2MXjtlWrtbY%3D 10.1016/j.neuroscience.2004.12.029 15837120
-
Goodenough S, Schleusner D, Pietrzik C, Skutella T, Behl C (2005) Glycogen synthase kinase 3beta links neuroprotection by 17beta-estradiol to key Alzheimer processes. Neuroscience 132(3):581-589
-
(2005)
Neuroscience
, vol.132
, Issue.3
, pp. 581-589
-
-
Goodenough, S.1
Schleusner, D.2
Pietrzik, C.3
Skutella, T.4
Behl, C.5
-
59
-
-
51649110188
-
Role of Dickkopf-1, an antagonist of the Wnt/beta-catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of tau phosphorylation
-
1:CAS:528:DC%2BD1cXhtVGqsLbI 10.1523/JNEUROSCI.2752-08.2008 2639789 18716201
-
Zhang QG, Wang R, Khan M, Mahesh V, Brann DW (2008) Role of Dickkopf-1, an antagonist of the Wnt/beta-catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of tau phosphorylation. J Neurosci 28(34):8430-41
-
(2008)
J Neurosci
, vol.28
, Issue.34
, pp. 8430-8441
-
-
Zhang, Q.G.1
Wang, R.2
Khan, M.3
Mahesh, V.4
Brann, D.W.5
-
60
-
-
48349124965
-
Estradiol attenuates tau hyperphosphorylation induced by upregulation of protein kinase-A
-
1:CAS:528:DC%2BD1cXptVKgu7o%3D 10.1007/s11064-008-9638-4 18338250
-
Liu XA, Zhu LQ, Zhang Q, Shi HR, Wang SH, Wang Q, Wang JZ (2008) Estradiol attenuates tau hyperphosphorylation induced by upregulation of protein kinase-A. Neurochem Res 33(9):1811-1820
-
(2008)
Neurochem Res
, vol.33
, Issue.9
, pp. 1811-1820
-
-
Liu, X.A.1
Zhu, L.Q.2
Zhang, Q.3
Shi, H.R.4
Wang, S.H.5
Wang, Q.6
Wang, J.Z.7
-
61
-
-
68549128998
-
Linking amyloid and tau pathology in Alzheimer's disease: The role of membrane cholesterol in Abeta-mediated tau toxicity
-
1:CAS:528:DC%2BD1MXpvFOmtLc%3D 10.1523/JNEUROSCI.2234-09.2009 19657019
-
Wray S, Noble W (2009) Linking amyloid and tau pathology in Alzheimer's disease: the role of membrane cholesterol in Abeta-mediated tau toxicity. J Neurosci 29(31):9665-9667
-
(2009)
J Neurosci
, vol.29
, Issue.31
, pp. 9665-9667
-
-
Wray, S.1
Noble, W.2
-
62
-
-
84455170369
-
Estrogen receptors and type 1 metabotropic glutamate receptors are interdependent in protecting cortical neurons against beta-amyloid toxicity
-
1:CAS:528:DC%2BC38XjtVSktro%3D 10.1124/mol.111.074021 21984253
-
Spampinato SF, Molinaro G, Merlo S, Iacovelli L, Caraci F, Battaglia G, Nicoletti F, Bruno V, Sortino MA (2012) Estrogen receptors and type 1 metabotropic glutamate receptors are interdependent in protecting cortical neurons against beta-amyloid toxicity. Mol Pharmacol 81(1):12-20
-
(2012)
Mol Pharmacol
, vol.81
, Issue.1
, pp. 12-20
-
-
Spampinato, S.F.1
Molinaro, G.2
Merlo, S.3
Iacovelli, L.4
Caraci, F.5
Battaglia, G.6
Nicoletti, F.7
Bruno, V.8
Sortino, M.A.9
-
63
-
-
15944411013
-
Estrogen and selective estrogen receptor modulators exert neuroprotective effects and stimulate the expression of selective Alzheimer's disease indicator-1, a recently discovered antiapoptotic gene, in human neuroblast long-term cell cultures
-
1:CAS:528:DC%2BD2MXisVOhtbY%3D 10.1210/jc.2004-0066 15585566
-
Benvenuti S, Luciani P, Vannelli GB, Gelmini S, Franceschi E, Serio M, Peri A (2005) Estrogen and selective estrogen receptor modulators exert neuroprotective effects and stimulate the expression of selective Alzheimer's disease indicator-1, a recently discovered antiapoptotic gene, in human neuroblast long-term cell cultures. J Clin Endocrinol Metab 90(3):1775-1782
-
(2005)
J Clin Endocrinol Metab
, vol.90
, Issue.3
, pp. 1775-1782
-
-
Benvenuti, S.1
Luciani, P.2
Vannelli, G.B.3
Gelmini, S.4
Franceschi, E.5
Serio, M.6
Peri, A.7
-
64
-
-
42149127057
-
Levels of estrogen receptors alpha and beta in frontal cortex of patients with Alzheimer's disease: Relationship to Mini-Mental State Examination scores
-
1:CAS:528:DC%2BD1cXitF2ktbc%3D 10.2174/156720508783884611 3268687 18288931
-
Kelly JF, Bienias JL, Shah A, Meeke KA, Schneider JA, Soriano E, Bennett DA (2008) Levels of estrogen receptors alpha and beta in frontal cortex of patients with Alzheimer's disease: relationship to Mini-Mental State Examination scores. Curr Alzheimer Res 5(1):45-51
-
(2008)
Curr Alzheimer Res
, vol.5
, Issue.1
, pp. 45-51
-
-
Kelly, J.F.1
Bienias, J.L.2
Shah, A.3
Meeke, K.A.4
Schneider, J.A.5
Soriano, E.6
Bennett, D.A.7
-
65
-
-
1942536628
-
Changes in estrogen receptor-alpha and -beta in the infundibular nucleus of the human hypothalamus are related to the occurrence of Alzheimer's disease neuropathology
-
1:CAS:528:DC%2BD2cXjt1eltLc%3D 10.1210/jc.2003-030862 15070964
-
Hestiantoro A, Swaab DF (2004) Changes in estrogen receptor-alpha and -beta in the infundibular nucleus of the human hypothalamus are related to the occurrence of Alzheimer's disease neuropathology. J Clin Endocrinol Metab 89(4):1912-1925
-
(2004)
J Clin Endocrinol Metab
, vol.89
, Issue.4
, pp. 1912-1925
-
-
Hestiantoro, A.1
Swaab, D.F.2
-
66
-
-
42449163010
-
Selective estrogen receptor modulators differentially regulate Alzheimer-like changes in female 3xTg-AD mice
-
1:CAS:528:DC%2BD1cXht1Gmsb7L 10.1210/en.2007-1346 18276750
-
Carroll JC, Pike CJ (2008) Selective estrogen receptor modulators differentially regulate Alzheimer-like changes in female 3xTg-AD mice. Endocrinology 149(5):2607-2611
-
(2008)
Endocrinology
, vol.149
, Issue.5
, pp. 2607-2611
-
-
Carroll, J.C.1
Pike, C.J.2
-
67
-
-
79952622790
-
Genistein ameliorates learning and memory deficits in amyloid beta(1-40) rat model of Alzheimer's disease
-
1:CAS:528:DC%2BC3MXjtFSgsrc%3D 10.1016/j.nlm.2010.12.001 21144907
-
Bagheri M, Joghataei MT, Mohseni S, Roghani M (2011) Genistein ameliorates learning and memory deficits in amyloid beta(1-40) rat model of Alzheimer's disease. Neurobiol Learn Mem 95(3):270-276
-
(2011)
Neurobiol Learn Mem
, vol.95
, Issue.3
, pp. 270-276
-
-
Bagheri, M.1
Joghataei, M.T.2
Mohseni, S.3
Roghani, M.4
-
68
-
-
84868115047
-
Alzheimer's disease, oestrogen and mitochondria: An ambiguous relationship
-
1:CAS:528:DC%2BC38XhtlGmsb7O 10.1007/s12035-012-8281-x 3443477 22678467
-
Grimm A, Lim YA, Mensah-Nyagan AG, Gotz J, Eckert A (2012) Alzheimer's disease, oestrogen and mitochondria: an ambiguous relationship. Mol Neurobiol 46(1):151-160
-
(2012)
Mol Neurobiol
, vol.46
, Issue.1
, pp. 151-160
-
-
Grimm, A.1
Lim, Y.A.2
Mensah-Nyagan, A.G.3
Gotz, J.4
Eckert, A.5
-
69
-
-
84871328175
-
Hormone therapy and Alzheimer disease dementia: New findings from the Cache County Study
-
1:CAS:528:DC%2BC38XhsF2nt7bE 10.1212/WNL.0b013e318271f823 23100399
-
Shao H, Breitner JC, Whitmer RA, Wang J, Hayden K, Wengreen H, Corcoran C, Tschanz J, Norton M, Munger R, Welsh-Bohmer K, Zandi PP (2012) Hormone therapy and Alzheimer disease dementia: new findings from the Cache County Study. Neurology 79(18):1846-1852
-
(2012)
Neurology
, vol.79
, Issue.18
, pp. 1846-1852
-
-
Shao, H.1
Breitner, J.C.2
Whitmer, R.A.3
Wang, J.4
Hayden, K.5
Wengreen, H.6
Corcoran, C.7
Tschanz, J.8
Norton, M.9
Munger, R.10
Welsh-Bohmer, K.11
Zandi, P.P.12
|