Fitness valleys constrain HIV-1's adaptation to its secondary chemokine coreceptor

Journal of Evolutionary Biology

Volumn 27, Issue 3, 2014, Pages 604-615

  Da Silva, J ^a   Wyatt, S K ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

CXCR4; Effective population size; Fitness epistasis; Fitness valley; Human immunodeficiency virus type 1; Stochastic tunnelling

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CXCR4 PROTEIN, HUMAN;

ADAPTATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; PHYSIOLOGY;

ADAPTATION, PHYSIOLOGICAL; HIV-1; HUMANS; RECEPTORS, CXCR4;

EID: 84894282840     PISSN: 1010061X     EISSN: 14209101     Source Type: Journal    
DOI: 10.1111/jeb.12329     Document Type: Article

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