-
1
-
-
27544475529
-
Advances in leishmaniasis
-
doi:10.1016/S0140-6736(05)67629-5. PubMed: 16257344
-
Murray HW, Berman JD, Davies CR, Saravia NG (2005) Advances in leishmaniasis. Lancet 366: 1561-1577. doi:10.1016/S0140-6736(05)67629-5. PubMed: 16257344.
-
(2005)
Lancet
, vol.366
, pp. 1561-1577
-
-
Murray, H.W.1
Berman, J.D.2
Davies, C.R.3
Saravia, N.G.4
-
2
-
-
33646823616
-
Chemotherapy in the treatment and control of leishmaniasis
-
doi:10.1016/S0065-308X(05)61006-8. PubMed: 16735166
-
Alvar J, Croft S, Olliaro P (2006) Chemotherapy in the treatment and control of leishmaniasis. Adv Parasitol 61: 223-274. doi:10.1016/S0065-308X(05) 61006-8. PubMed: 16735166.
-
(2006)
Adv Parasitol
, vol.61
, pp. 223-274
-
-
Alvar, J.1
Croft, S.2
Olliaro, P.3
-
3
-
-
0033509735
-
Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani
-
doi:10.1086/314896. PubMed: 10395884
-
Lira R, Sundar S, Makharia A, Kenney R, Gam A et al. (1999) Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani. J Infect Dis 180: 564-567. doi:10.1086/314896. PubMed: 10395884.
-
(1999)
J Infect Dis
, vol.180
, pp. 564-567
-
-
Lira, R.1
Sundar, S.2
Makharia, A.3
Kenney, R.4
Gam, A.5
-
4
-
-
0034780949
-
Drug resistance in Indian visceral leishmaniasis
-
doi:10.1046/j.1365-3156.2001.00778.x. PubMed: 11703838
-
Sundar S (2001) Drug resistance in Indian visceral leishmaniasis. Trop Med Int Health 6: 849-854. doi:10.1046/j.1365-3156.2001.00778.x. PubMed: 11703838.
-
(2001)
Trop Med Int Health
, vol.6
, pp. 849-854
-
-
Sundar, S.1
-
5
-
-
0035295431
-
Leishmania species, drug unresponsiveness and visceral leishmaniasis in Bihar, India
-
Thakur CP, Dedet JP, Narain S, Pratlong F (2001) Leishmania species, drug unresponsiveness and visceral leishmaniasis in Bihar, India. Trans R Soc Trop Med Hyg 95: 187-189.
-
(2001)
Trans R Soc Trop Med Hyg
, vol.95
, pp. 187-189
-
-
Thakur, C.P.1
Dedet, J.P.2
Narain, S.3
Pratlong, F.4
-
6
-
-
34250717991
-
Injectable paromomycin for Visceral leishmaniasis in India
-
doi:10.1056/NEJMoa066536. PubMed: 17582067
-
Sundar S, Jha TK, Thakur CP, Sinha PK, Bhattacharya SK (2007) Injectable paromomycin for Visceral leishmaniasis in India. N Engl J Med 356: 2571-2581. doi:10.1056/NEJMoa066536. PubMed: 17582067.
-
(2007)
N Engl J Med
, vol.356
, pp. 2571-2581
-
-
Sundar, S.1
Jha, T.K.2
Thakur, C.P.3
Sinha, P.K.4
Bhattacharya, S.K.5
-
7
-
-
0032488285
-
Trial of oral miltefosine for visceral leishmaniasis
-
doi:10.1016/S0140-6736(98)04367-0. PubMed: 9851383
-
Sundar S, Rosenkaimer F, Makharia MK, Goyal AK, Mandal AK et al. (1998) Trial of oral miltefosine for visceral leishmaniasis. Lancet 352: 1821-1823. doi:10.1016/S0140-6736(98)04367-0. PubMed: 9851383.
-
(1998)
Lancet
, vol.352
, pp. 1821-1823
-
-
Sundar, S.1
Rosenkaimer, F.2
Makharia, M.K.3
Goyal, A.K.4
Mandal, A.K.5
-
8
-
-
58449083522
-
Anthropometrically derived dosing and drug costing calculations for treating visceral leishmaniasis in Bihar, India
-
doi:10.1111/j.1365-3156.2008.02195.x. PubMed: 19121150
-
Olliaro P, Sundar S (2009) Anthropometrically derived dosing and drug costing calculations for treating visceral leishmaniasis in Bihar, India. Trop Med Int Health 14: 88-92. doi:10.1111/j.1365-3156.2008.02195.x. PubMed: 19121150.
-
(2009)
Trop Med Int Health
, vol.14
, pp. 88-92
-
-
Olliaro, P.1
Sundar, S.2
-
9
-
-
33748647413
-
Liposomal amphotericin B for the treatment of visceral leishmaniasis
-
doi:10.1086/507530. PubMed: 16941377
-
Bern C, Adler-Moore J, Berenguer J, Boelaert M, den Boer M et al. (2006) Liposomal amphotericin B for the treatment of visceral leishmaniasis. Clin Infect Dis 43: 917-924. doi:10.1086/507530. PubMed: 16941377.
-
(2006)
Clin Infect Dis
, vol.43
, pp. 917-924
-
-
Bern, C.1
Adler-Moore, J.2
Berenguer, J.3
Boelaert, M.4
Den Boer, M.5
-
10
-
-
35548987998
-
Visceral leishmaniasis: What are the needs for diagnosis, treatment and control?
-
PubMed: 17938629
-
Chappuis F, Sundar S, Hailu A, Ghalib H, Rijal S et al. (2007) Visceral leishmaniasis: what are the needs for diagnosis, treatment and control? Nat Rev Microbiol 5: 873-882. PubMed: 17938629.
-
(2007)
Nat Rev Microbiol
, vol.5
, pp. 873-882
-
-
Chappuis, F.1
Sundar, S.2
Hailu, A.3
Ghalib, H.4
Rijal, S.5
-
11
-
-
0035830909
-
Novel Intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani
-
doi:10.1074/jbc.M005423200. PubMed: 11110784
-
Shaked-Mishan P, Ulrich N, Ephros M, Zilberstein D (2001) Novel Intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani. J Biol Chem 276: 3971-3976. doi:10.1074/jbc.M005423200. PubMed: 11110784.
-
(2001)
J Biol Chem
, vol.276
, pp. 3971-3976
-
-
Shaked-Mishan, P.1
Ulrich, N.2
Ephros, M.3
Zilberstein, D.4
-
12
-
-
3843084085
-
Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin
-
doi:10.1074/ jbc.M403959200. PubMed: 15138256
-
Gourbal B, Sonuc N, Bhattacharjee H, Legare D, Sundar S et al. (2004) Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin. J Biol Chem 279: 31010-31017. doi:10.1074/ jbc.M403959200. PubMed: 15138256.
-
(2004)
J Biol Chem
, vol.279
, pp. 31010-31017
-
-
Gourbal, B.1
Sonuc, N.2
Bhattacharjee, H.3
Legare, D.4
Sundar, S.5
-
13
-
-
25144440472
-
Modulation in aquaglyceroporin AQP1 gene transcript levels in drug-resistant Leishmania
-
doi:10.1111/j.1365-2958.2005.04782.x. PubMed: 16135234
-
Marquis N, Gourbal B, Rosen BP, Mukhopadhyay R, Ouellette M (2005) Modulation in aquaglyceroporin AQP1 gene transcript levels in drug-resistant Leishmania. Mol Microbiol 57: 1690-1699. doi:10.1111/j.1365-2958.2005.04782.x. PubMed: 16135234.
-
(2005)
Mol Microbiol
, vol.57
, pp. 1690-1699
-
-
Marquis, N.1
Gourbal, B.2
Rosen, B.P.3
Mukhopadhyay, R.4
Ouellette, M.5
-
14
-
-
27644513649
-
Gene expression analysis of the mechanism of natural Sb(V) resistance in Leishmania donovani isolates from Nepal
-
doi:10.1128/AAC.49.11.4616-4621.2005. PubMed: 16251303
-
Decuypere S, Rijal S, Yardley V, De Doncker S, Laurent T et al. (2005) Gene expression analysis of the mechanism of natural Sb(V) resistance in Leishmania donovani isolates from Nepal. Antimicrob Agents Chemother 49: 4616-4621. doi:10.1128/AAC.49.11.4616-4621.2005. PubMed: 16251303.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 4616-4621
-
-
Decuypere, S.1
Rijal, S.2
Yardley, V.3
De Doncker, S.4
Laurent, T.5
-
15
-
-
77950336943
-
Assessing aquaglyceroporin gene status and expression profile in antimony-susceptible and -resistant clinical isolates of Leishmania donovani from India
-
doi:10.1093/jac/dkp468. PubMed: 20067981
-
Mandal S, Maharjan M, Singh S, Chatterjee M, Madhubala R (2010) Assessing aquaglyceroporin gene status and expression profile in antimony-susceptible and -resistant clinical isolates of Leishmania donovani from India. J Antimicrob Chemother 65: 496-507. doi:10.1093/jac/dkp468. PubMed: 20067981.
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 496-507
-
-
Mandal, S.1
Maharjan, M.2
Singh, S.3
Chatterjee, M.4
Madhubala, R.5
-
16
-
-
0025822869
-
Drug resistance and P-glycoprotein gene amplification in the protozoan parasite Leishmania
-
doi:10.1016/0923-2508(91)90089-S. PubMed: 1961984
-
Ouellette M, Borst P (1991) Drug resistance and P-glycoprotein gene amplification in the protozoan parasite Leishmania. Res Microbiol 142: 737-746. doi:10.1016/0923-2508(91)90089-S. PubMed: 1961984.
-
(1991)
Res Microbiol
, vol.142
, pp. 737-746
-
-
Ouellette, M.1
Borst, P.2
-
17
-
-
0027157185
-
Homologous recombination between direct repeat sequences yields P-glycoprotein containing amplicons in arsenite resistant Leishmania
-
doi:10.1093/nar/21.8.1895. PubMed: 8098523
-
Grondin K, Papadopoulou B, Ouellette M (1993) Homologous recombination between direct repeat sequences yields P-glycoprotein containing amplicons in arsenite resistant Leishmania. Nucleic Acids Res 21: 1895-1901. doi:10.1093/nar/21.8.1895. PubMed: 8098523.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 1895-1901
-
-
Grondin, K.1
Papadopoulou, B.2
Ouellette, M.3
-
18
-
-
0030924243
-
Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae
-
doi:10.1093/emboj/16.11.3057. PubMed: 9214623
-
Grondin K, Haimeur A, Mukhopadhyay R, Rosen BP, Ouellette M (1997) Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae. EMBO J 16: 3057-3065. doi:10.1093/emboj/16.11.3057. PubMed: 9214623.
-
(1997)
EMBO J
, vol.16
, pp. 3057-3065
-
-
Grondin, K.1
Haimeur, A.2
Mukhopadhyay, R.3
Rosen, B.P.4
Ouellette, M.5
-
19
-
-
0034732687
-
Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (SbIII) resistant Leishmania tarentolae
-
doi:10.1016/S0166-6851(00)00187-0. PubMed: 10802326
-
Haimeur A, Brochu C, Genest P, Papadopoulou B, Ouellette M (2000) Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (SbIII) resistant Leishmania tarentolae. Mol Biochem Parasitol 108: 131-135. doi:10.1016/S0166-6851(00)00187-0. PubMed: 10802326.
-
(2000)
Mol Biochem Parasitol
, vol.108
, pp. 131-135
-
-
Haimeur, A.1
Brochu, C.2
Genest, P.3
Papadopoulou, B.4
Ouellette, M.5
-
20
-
-
63249133197
-
Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum
-
doi:10.1093/nar/gkn1069. PubMed: 19129236
-
Leprohon P, Légaré D, Raymond F, Madore E, Hardiman G et al. (2009) Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum. Nucleic Acids Res 37: 1387-1399. doi:10.1093/nar/gkn1069. PubMed: 19129236.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1387-1399
-
-
Leprohon, P.1
Légaré, D.2
Raymond, F.3
Madore, E.4
Hardiman, G.5
-
21
-
-
34249747773
-
Characterization of natural antimony resistance in Leishmania donovani isolates
-
PubMed: 17426170
-
Mittal MK, Rai S, Ashutosh, Ravinder, Gupta S et al. (2007) Characterization of natural antimony resistance in Leishmania donovani isolates. Am J Trop Med Hyg 76: 681-688. PubMed: 17426170.
-
(2007)
Am J Trop Med Hyg
, vol.76
, pp. 681-688
-
-
Mittal, M.K.1
Rai, S.2
Ashutosh3
Ravinder4
Gupta, S.5
-
22
-
-
33947528405
-
Role of ABC transporter MRPA, gamma-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani
-
PubMed: 17213267
-
Mukherjee A, Padmanabhan PK, Singh S, Roy G, Girard I et al. (2007) Role of ABC transporter MRPA, gamma-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani. J Antimicrob Chemother 59: 204-211. PubMed: 17213267.
-
(2007)
J Antimicrob Chemother
, vol.59
, pp. 204-211
-
-
Mukherjee, A.1
Padmanabhan, P.K.2
Singh, S.3
Roy, G.4
Girard, I.5
-
23
-
-
0029841913
-
Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania
-
doi:10.1073/pnas.93.19.10383. PubMed: 8816809
-
Mukhopadhyay R, Dey S, Xu N, Gage D, Lightbody J et al. (1996) Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania. Proc Natl Acad Sci U S A 93: 10383-10387. doi:10.1073/pnas.93.19. 10383. PubMed: 8816809.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 10383-10387
-
-
Mukhopadhyay, R.1
Dey, S.2
Xu, N.3
Gage, D.4
Lightbody, J.5
-
24
-
-
0031282335
-
Efflux systems and increased trypanothione levels in arsenite-resistant Leishmania
-
doi:10.1006/expr.1997.4222. PubMed: 9371094
-
Légaré D, Papadopoulou B, Roy G, Mukhopadhyay R, Haimeur A et al. (1997) Efflux systems and increased trypanothione levels in arsenite-resistant Leishmania. Exp Parasitol 87: 275-282. doi:10.1006/expr.1997. 4222. PubMed: 9371094.
-
(1997)
Exp Parasitol
, vol.87
, pp. 275-282
-
-
Légaré, D.1
Papadopoulou, B.2
Roy, G.3
Mukhopadhyay, R.4
Haimeur, A.5
-
25
-
-
0032744407
-
Elevated levels of polyamines and trypanothione resulting from overexpression of the ornithine decarboxylase gene in arseniteresistant Leishmania
-
doi:10.1046/j.1365-2958.1999.01634.x. PubMed: 10564512
-
Haimeur A, Guimond C, Pilote S, Mukhopadhyay R, Rosen BP et al. (1999) Elevated levels of polyamines and trypanothione resulting from overexpression of the ornithine decarboxylase gene in arseniteresistant Leishmania. Mol Microbiol 34: 726-735. doi:10.1046/j.1365-2958.1999.01634.x. PubMed: 10564512.
-
(1999)
Mol Microbiol
, vol.34
, pp. 726-735
-
-
Haimeur, A.1
Guimond, C.2
Pilote, S.3
Mukhopadhyay, R.4
Rosen, B.P.5
-
26
-
-
10744222969
-
Modulation of gene expression in Leishmania drug resistant mutants as determined by targeted DNA microarrays
-
doi:10.1093/nar/gkg806. PubMed: 14530437
-
Guimond C, Trudel N, Brochu C, Marquis N, El Fadili A et al. (2003) Modulation of gene expression in Leishmania drug resistant mutants as determined by targeted DNA microarrays. Nucleic Acids Res 31: 5886-5896. doi:10.1093/nar/gkg806. PubMed: 14530437.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 5886-5896
-
-
Guimond, C.1
Trudel, N.2
Brochu, C.3
Marquis, N.4
El Fadili, A.5
-
27
-
-
70449562301
-
The gamma-glutamylcysteine synthetase gene of Leishmania is essential and involved in response to oxidants
-
doi:10.1111/j.1365-2958.2009.06907.x. PubMed: 19818018
-
Mukherjee A, Roy G, Guimond C, Ouellette M (2009) The gamma-glutamylcysteine synthetase gene of Leishmania is essential and involved in response to oxidants. Mol Microbiol 74: 914-927. doi:10.1111/j.1365-2958. 2009.06907.x. PubMed: 19818018.
-
(2009)
Mol Microbiol
, vol.74
, pp. 914-927
-
-
Mukherjee, A.1
Roy, G.2
Guimond, C.3
Ouellette, M.4
-
28
-
-
34948899791
-
Increased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimony
-
PubMed: 17612420
-
Mandal G, Wyllie S, Singh N, Sundar S, Fairlamb AH et al. (2007) Increased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimony. Parasitology 134: 1679-1687. PubMed: 17612420.
-
(2007)
Parasitology
, vol.134
, pp. 1679-1687
-
-
Mandal, G.1
Wyllie, S.2
Singh, N.3
Sundar, S.4
Fairlamb, A.H.5
-
29
-
-
34248397955
-
Differential gene expression analysis in antimony-unresponsive Indian kala azar (visceral leishmaniasis) clinical isolates by DNA microarray
-
doi:10.1017/S0031182007002284. PubMed: 17306059
-
Singh N, Almeida R, Kothari H, Kumar P, Mandal G et al. (2007) Differential gene expression analysis in antimony-unresponsive Indian kala azar (visceral leishmaniasis) clinical isolates by DNA microarray. Parasitology 134: 777-787. doi:10.1017/S0031182007002284. PubMed: 17306059.
-
(2007)
Parasitology
, vol.134
, pp. 777-787
-
-
Singh, N.1
Almeida, R.2
Kothari, H.3
Kumar, P.4
Mandal, G.5
-
30
-
-
33847219040
-
Molecular mechanisms of antimony resistance in Leishmania
-
doi:10.1099/jmm.0.46841-0. PubMed: 17244793
-
Ashutosh, Sundar S, Goyal N (2007) Molecular mechanisms of antimony resistance in Leishmania. J Med Microbiol 56: 143-153. doi:10.1099/jmm.0.46841- 0. PubMed: 17244793.
-
(2007)
J Med Microbiol
, vol.56
, pp. 143-153
-
-
Ashutosh1
Sundar, S.2
Goyal, N.3
-
31
-
-
33846554383
-
A proteomics screen implicates HSP83 and a small kinetoplastid calpain-related protein in drug resistance in Leishmania donovani clinical field isolates by modulating drug-induced programmed cell death
-
PubMed: 17050524
-
Vergnes B, Gourbal B, Girard I, Sundar S, Drummelsmith J et al. (2007) A proteomics screen implicates HSP83 and a small kinetoplastid calpain-related protein in drug resistance in Leishmania donovani clinical field isolates by modulating drug-induced programmed cell death. Mol Cell Proteomics 6: 88-101. PubMed: 17050524.
-
(2007)
Mol Cell Proteomics
, vol.6
, pp. 88-101
-
-
Vergnes, B.1
Gourbal, B.2
Girard, I.3
Sundar, S.4
Drummelsmith, J.5
-
32
-
-
68049132858
-
Down regulation of KMP-11 in Leishmania infantum axenic antimony resistant amastigotes as revealed by a proteomic screen
-
doi:10.1016/j.exppara.2009.05.013. PubMed: 19500579
-
El Fadili K, Drummelsmith J, Roy G, Jardim A, Ouellette M (2009) Down regulation of KMP-11 in Leishmania infantum axenic antimony resistant amastigotes as revealed by a proteomic screen. Exp Parasitol 123: 51-57. doi:10.1016/j.exppara.2009.05.013. PubMed: 19500579.
-
(2009)
Exp Parasitol
, vol.123
, pp. 51-57
-
-
El Fadili, K.1
Drummelsmith, J.2
Roy, G.3
Jardim, A.4
Ouellette, M.5
-
33
-
-
77956577653
-
Proteome mapping of overexpressed membrane-enriched and cytosolic proteins in sodium antimony gluconate (SAG) resistant clinical isolate of Leishmania donovani
-
doi:10.1111/j.1365-2125.2010.03716.x. PubMed: 20840452
-
Kumar A, Sisodia B, Misra P, Sundar S, Shasany AK et al. (2010) Proteome mapping of overexpressed membrane-enriched and cytosolic proteins in sodium antimony gluconate (SAG) resistant clinical isolate of Leishmania donovani. Br J Clin Pharmacol 70: 609-617. doi:10.1111/j.1365-2125.2010.03716.x. PubMed: 20840452.
-
(2010)
Br J Clin Pharmacol
, vol.70
, pp. 609-617
-
-
Kumar, A.1
Sisodia, B.2
Misra, P.3
Sundar, S.4
Shasany, A.K.5
-
34
-
-
80051783081
-
Differential expression of proteins in antimony-susceptible and -resistant isolates of Leishmania donovani
-
doi:10.1016/j.molbiopara.2011.06.004. PubMed: 21736901
-
Biyani N, Singh AK, Mandal S, Chawla B, Madhubala R (2011) Differential expression of proteins in antimony-susceptible and -resistant isolates of Leishmania donovani. Mol Biochem Parasitol 179: 91-99. doi:10.1016/j.molbiopara. 2011.06.004. PubMed: 21736901.
-
(2011)
Mol Biochem Parasitol
, vol.179
, pp. 91-99
-
-
Biyani, N.1
Singh, A.K.2
Mandal, S.3
Chawla, B.4
Madhubala, R.5
-
35
-
-
84859612403
-
Discovery of factors linked to antimony resistance in Leishmania panamensis through differential proteome analysis
-
doi:10.1016/j.molbiopara.2012.03.002. PubMed: 22449941
-
Walker J, Gongora R, Vasquez JJ, Drummelsmith J, Burchmore R et al. (2012) Discovery of factors linked to antimony resistance in Leishmania panamensis through differential proteome analysis. Mol Biochem Parasitol 183: 166-176. doi:10.1016/j.molbiopara.2012.03.002. PubMed: 22449941.
-
(2012)
Mol Biochem Parasitol
, vol.183
, pp. 166-176
-
-
Walker, J.1
Gongora, R.2
Vasquez, J.J.3
Drummelsmith, J.4
Burchmore, R.5
-
36
-
-
83055168329
-
Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance
-
doi:10.1101/gr.123430.111. PubMed: 22038251
-
Downing T, Imamura H, Decuypere S, Clark TG, Coombs GH et al. (2011) Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance. Genome Res 21: 2143-2156. doi:10.1101/gr.123430.111. PubMed: 22038251.
-
(2011)
Genome Res
, vol.21
, pp. 2143-2156
-
-
Downing, T.1
Imamura, H.2
Decuypere, S.3
Clark, T.G.4
Coombs, G.H.5
-
38
-
-
20944442198
-
Role of the ABC transporter MRPA (PGPA) in antimony resistance in Leishmania infantum axenic and intracellular amastigotes
-
doi:10.1128/AAC.49.5.1988-1993.2005. PubMed: 15855523
-
El Fadili K, Messier N, Leprohon P, Roy G, Guimond C et al. (2005) Role of the ABC transporter MRPA (PGPA) in antimony resistance in Leishmania infantum axenic and intracellular amastigotes. Antimicrob Agents Chemother 49: 1988-1993. doi:10.1128/AAC.49.5.1988-1993.2005. PubMed: 15855523.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 1988-1993
-
-
El Fadili, K.1
Messier, N.2
Leprohon, P.3
Roy, G.4
Guimond, C.5
-
39
-
-
67049116076
-
Intracellular localization of the ABCC proteins of Leishmania and their role in resistance to antimonials
-
doi:10.1128/AAC.01474-08. PubMed: 19307364
-
Leprohon P, Légaré D, Ouellette M (2009) Intracellular localization of the ABCC proteins of Leishmania and their role in resistance to antimonials. Antimicrob Agents Chemother 53: 2646-2649. doi:10.1128/AAC.01474- 08. PubMed: 19307364.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 2646-2649
-
-
Leprohon, P.1
Légaré, D.2
Ouellette, M.3
-
40
-
-
80053395366
-
Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania
-
Moreira W, Leprohon P, Ouellette M (2011) Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania. Cell Death Dis 2: e201.
-
(2011)
Cell Death Dis
, vol.2
-
-
Moreira, W.1
Leprohon, P.2
Ouellette, M.3
-
41
-
-
84864598086
-
Analysis of Membrane-Enriched and High Molecular Weight Proteins in Leishmania infantum Promastigotes and Axenic Amastigotes
-
doi:10.1021/pr201248h. PubMed: 22716046
-
Brotherton MC, Racine G, Ouameur AA, Leprohon P, Papadopoulou B et al. (2012) Analysis of Membrane-Enriched and High Molecular Weight Proteins in Leishmania infantum Promastigotes and Axenic Amastigotes. J Proteome Res 11: 3974-3985. doi:10.1021/pr201248h. PubMed: 22716046.
-
(2012)
J Proteome Res
, vol.11
, pp. 3974-3985
-
-
Brotherton, M.C.1
Racine, G.2
Ouameur, A.A.3
Leprohon, P.4
Papadopoulou, B.5
-
42
-
-
77955452986
-
Analysis of stage-specific expression of basic proteins in Leishmania infantum
-
doi:10.1021/pr100048m. PubMed: 20583757
-
Brotherton MC, Racine G, Foucher AL, Drummelsmith J, Papadopoulou B et al. (2010) Analysis of stage-specific expression of basic proteins in Leishmania infantum. J Proteome Res 9: 3842-3853. doi:10.1021/pr100048m. PubMed: 20583757.
-
(2010)
J Proteome Res
, vol.9
, pp. 3842-3853
-
-
Brotherton, M.C.1
Racine, G.2
Foucher, A.L.3
Drummelsmith, J.4
Papadopoulou, B.5
-
43
-
-
0029927505
-
Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels
-
doi:10.1021/ac950914h. PubMed: 8779443
-
Shevchenko A, Wilm M, Vorm O, Mann M (1996) Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 68: 850-858. doi:10.1021/ac950914h. PubMed: 8779443.
-
(1996)
Anal Chem
, vol.68
, pp. 850-858
-
-
Shevchenko, A.1
Wilm, M.2
Vorm, O.3
Mann, M.4
-
44
-
-
0037444512
-
Fast-response proteomics by accelerated in-gel digestion of proteins
-
doi:10.1021/ac026136s. PubMed: 12659189
-
Havlis J, Thomas H, Sebela M, Shevchenko A (2003) Fast-response proteomics by accelerated in-gel digestion of proteins. Anal Chem 75: 1300-1306. doi:10.1021/ac026136s. PubMed: 12659189.
-
(2003)
Anal Chem
, vol.75
, pp. 1300-1306
-
-
Havlis, J.1
Thomas, H.2
Sebela, M.3
Shevchenko, A.4
-
45
-
-
34848889259
-
The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra
-
doi:10.1074/mcp.T600050-MCP200. PubMed: 17533153
-
Shilov IV, Seymour SL, Patel AA, Loboda A, Tang WH et al. (2007) The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra. Mol Cell Proteomics 6: 1638-1655. doi:10.1074/mcp.T600050-MCP200. PubMed: 17533153.
-
(2007)
Mol Cell Proteomics
, vol.6
, pp. 1638-1655
-
-
Shilov, I.V.1
Seymour, S.L.2
Patel, A.A.3
Loboda, A.4
Tang, W.H.5
-
46
-
-
84856934639
-
Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species
-
doi:10.1093/nar/gkr834. PubMed: 21998295
-
Raymond F, Boisvert S, Roy G, Ritt JF, Légaré D et al. (2012) Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species. Nucleic Acids Res 40: 1131-1147. doi:10.1093/nar/gkr834. PubMed: 21998295.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 1131-1147
-
-
Raymond, F.1
Boisvert, S.2
Roy, G.3
Ritt, J.F.4
Légaré, D.5
-
47
-
-
34347339518
-
Comparative genomic analysis of three Leishmania species that cause diverse human disease
-
doi:10.1038/ng2053. PubMed: 17572675
-
Peacock CS, Seeger K, Harris D, Murphy L, Ruiz JC et al. (2007) Comparative genomic analysis of three Leishmania species that cause diverse human disease. Nat Genet 39: 839-847. doi:10.1038/ng2053. PubMed: 17572675.
-
(2007)
Nat Genet
, vol.39
, pp. 839-847
-
-
Peacock, C.S.1
Seeger, K.2
Harris, D.3
Murphy, L.4
Ruiz, J.C.5
-
48
-
-
75549088870
-
TriTrypDB: A functional genomic resource for the Trypanosomatidae
-
doi:10.1093/nar/gkq373. PubMed: 19843604
-
Aslett M, Aurrecoechea C, Berriman M, Brestelli J, Brunk BP et al. (2010) TriTrypDB: a functional genomic resource for the Trypanosomatidae. Nucleic Acids Res 38: D457-D462. doi:10.1093/nar/gkq373. PubMed: 19843604.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Aslett, M.1
Aurrecoechea, C.2
Berriman, M.3
Brestelli, J.4
Brunk, B.P.5
-
49
-
-
67649884743
-
Fast and accurate short read alignment with Burrows-Wheeler transform
-
doi:10.1093/bioinformatics/btp324. PubMed: 19451168
-
Li H, Durbin R (2009) Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25: 1754-1760. doi:10.1093/ bioinformatics/btp324. PubMed: 19451168.
-
(2009)
Bioinformatics
, vol.25
, pp. 1754-1760
-
-
Li, H.1
Durbin, R.2
-
50
-
-
68549104404
-
The Sequence Alignment/Map format and SAMtools
-
doi:10.1093/bioinformatics/btp352. PubMed: 19505943
-
Li H, Handsaker B, Wysoker A, Fennell T, Ruan J et al. (2009) The Sequence Alignment/Map format and SAMtools. Bioinformatics 25: 2078-2079. doi:10.1093/bioinformatics/btp352. PubMed: 19505943.
-
(2009)
Bioinformatics
, vol.25
, pp. 2078-2079
-
-
Li, H.1
Handsaker, B.2
Wysoker, A.3
Fennell, T.4
Ruan, J.5
-
51
-
-
78650568308
-
SAMStat: Monitoring biases in next generation sequencing data
-
doi:10.1093/bioinformatics/btq614. PubMed: 21088025
-
Lassmann T, Hayashizaki Y, Daub CO (2011) SAMStat: monitoring biases in next generation sequencing data. Bioinformatics 27: 130-131. doi:10.1093/bioinformatics/btq614. PubMed: 21088025.
-
(2011)
Bioinformatics
, vol.27
, pp. 130-131
-
-
Lassmann, T.1
Hayashizaki, Y.2
Daub, C.O.3
-
52
-
-
0026779424
-
A novel antifolate resistance gene on the amplified H circle of Leishmania
-
PubMed: 1396560
-
Papadopoulou B, Roy G, Ouellette M (1992) A novel antifolate resistance gene on the amplified H circle of Leishmania. EMBO J 11: 3601-3608. PubMed: 1396560.
-
(1992)
EMBO J
, vol.11
, pp. 3601-3608
-
-
Papadopoulou, B.1
Roy, G.2
Ouellette, M.3
-
53
-
-
84867077750
-
Novel insights into genome plasticity in Eukaryotes: Mosaic aneuploidy in Leishmania
-
PubMed: 22857263
-
Sterkers Y, Lachaud L, Bourgeois N, Crobu L, Bastien P et al. (2012) Novel insights into genome plasticity in Eukaryotes: mosaic aneuploidy in Leishmania. Mol Microbiol 86: 15-23. PubMed: 22857263.
-
(2012)
Mol Microbiol
, vol.86
, pp. 15-23
-
-
Sterkers, Y.1
Lachaud, L.2
Bourgeois, N.3
Crobu, L.4
Bastien, P.5
-
54
-
-
0025371936
-
The major Leishmania donovani chagasi surface glycoprotein in tunicamycin-resistant promastigotes
-
PubMed: 2191040
-
Wilson ME, Hardin KK (1990) The major Leishmania donovani chagasi surface glycoprotein in tunicamycin-resistant promastigotes. J Immunol 144: 4825-4834. PubMed: 2191040.
-
(1990)
J Immunol
, vol.144
, pp. 4825-4834
-
-
Wilson, M.E.1
Hardin, K.K.2
-
55
-
-
0028223568
-
Expression of the major surface glycoprotein of Leishmania, gp63, in wild-type and sinefungin-resistant promastigotes
-
doi:10.1111/j.1432-1033.1994.tb18966.x. PubMed: 8033909
-
Soteriadou KP, Tzinia AK, Mamalaki A, Phelouzat MA, Lawrence F et al. (1994) Expression of the major surface glycoprotein of Leishmania, gp63, in wild-type and sinefungin-resistant promastigotes. Eur J Biochem 223: 61-68. doi:10.1111/j.1432-1033.1994.tb18966.x. PubMed: 8033909.
-
(1994)
Eur J Biochem
, vol.223
, pp. 61-68
-
-
Soteriadou, K.P.1
Tzinia, A.K.2
Mamalaki, A.3
Phelouzat, M.A.4
Lawrence, F.5
-
56
-
-
77952997887
-
Overexpression of histone H2A modulates drug susceptibility in Leishmania parasites
-
doi:10.1016/j.ijantimicag.2010.03.012. PubMed: 20427152
-
Singh R, Kumar D, Duncan RC, Nakhasi HL, Salotra P (2010) Overexpression of histone H2A modulates drug susceptibility in Leishmania parasites. Int J Antimicrob Agents 36: 50-57. doi:10.1016/j.ijantimicag.2010.03.012. PubMed: 20427152.
-
(2010)
Int J Antimicrob Agents
, vol.36
, pp. 50-57
-
-
Singh, R.1
Kumar, D.2
Duncan, R.C.3
Nakhasi, H.L.4
Salotra, P.5
-
57
-
-
0022392239
-
Induction of heat shock and stress proteins in promastigotes of three Leishmania species
-
doi:10.1073/pnas.82.13.4414. PubMed: 3859870
-
Lawrence F, Robert-Gero M (1985) Induction of heat shock and stress proteins in promastigotes of three Leishmania species. Proc Natl Acad Sci U S A 82: 4414-4417. doi:10.1073/pnas.82.13.4414. PubMed: 3859870.
-
(1985)
Proc Natl Acad Sci U S A
, vol.82
, pp. 4414-4417
-
-
Lawrence, F.1
Robert-Gero, M.2
-
58
-
-
7644219918
-
The heat shock protein HSP70 and heat shock cognate protein HSC70 contribute to antimony tolerance in the protozoan parasite leishmania
-
doi:10.1379/CSC-15R1.1. PubMed: 15544167
-
Brochu C, Haimeur A, Ouellette M (2004) The heat shock protein HSP70 and heat shock cognate protein HSC70 contribute to antimony tolerance in the protozoan parasite leishmania. Cell Stress Chaperones 9: 294-303. doi:10.1379/CSC-15R1.1. PubMed: 15544167.
-
(2004)
Cell Stress Chaperones
, vol.9
, pp. 294-303
-
-
Brochu, C.1
Haimeur, A.2
Ouellette, M.3
-
59
-
-
0034950111
-
Antimonial-mediated DNA fragmentation in Leishmania infantum amastigotes
-
doi:10.1128/AAC.45.7.2064-2069.2001. PubMed: 11408224
-
Sereno D, Holzmuller P, Mangot I, Cuny G, Ouaissi A et al. (2001) Antimonial-mediated DNA fragmentation in Leishmania infantum amastigotes. Antimicrob Agents Chemother 45: 2064-2069. doi:10.1128/AAC.45.7.2064-2069.2001. PubMed: 11408224.
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 2064-2069
-
-
Sereno, D.1
Holzmuller, P.2
Mangot, I.3
Cuny, G.4
Ouaissi, A.5
-
60
-
-
0036144405
-
Programmed cell death in the unicellular protozoan parasite Leishmania
-
doi:10.1038/sj.cdd.4400952. PubMed: 11803374
-
Lee N, Bertholet S, Debrabant A, Muller J, Duncan R et al. (2002) Programmed cell death in the unicellular protozoan parasite Leishmania. Cell Death Differ 9: 53-64. doi:10.1038/sj.cdd.4400952. PubMed: 11803374.
-
(2002)
Cell Death Differ
, vol.9
, pp. 53-64
-
-
Lee, N.1
Bertholet, S.2
Debrabant, A.3
Muller, J.4
Duncan, R.5
-
61
-
-
0042090390
-
Antimonial-induced increase in intracellular Ca2+ through non-selective cation channels in the host and the parasite is responsible for apoptosis of intracellular Leishmania donovani amastigotes
-
doi:10.1074/jbc.M301975200. PubMed: 12707265
-
Sudhandiran G, Shaha C (2003) Antimonial-induced increase in intracellular Ca2+ through non-selective cation channels in the host and the parasite is responsible for apoptosis of intracellular Leishmania donovani amastigotes. J Biol Chem 278: 25120-25132. doi:10.1074/jbc.M301975200. PubMed: 12707265.
-
(2003)
J Biol Chem
, vol.278
, pp. 25120-25132
-
-
Sudhandiran, G.1
Shaha, C.2
-
62
-
-
34247387973
-
Cancer drug resistance: The central role of the karyotype
-
doi:10.1016/j.drup.2007.02.003. PubMed: 17387035
-
Duesberg P, Li R, Sachs R, Fabarius A, Upender MB et al. (2007) Cancer drug resistance: the central role of the karyotype. Drug Resist Updat 10: 51-58. doi:10.1016/j.drup.2007.02.003. PubMed: 17387035.
-
(2007)
Drug Resist Updat
, vol.10
, pp. 51-58
-
-
Duesberg, P.1
Li, R.2
Sachs, R.3
Fabarius, A.4
Upender, M.B.5
-
63
-
-
33746506280
-
Aneuploidy and isochromosome formation in drug-resistant Candida albicans
-
doi:10.1126/science.1128242. PubMed: 16857942
-
Selmecki A, Forche A, Berman J (2006) Aneuploidy and isochromosome formation in drug-resistant Candida albicans. Science 313: 367-370. doi:10.1126/science.1128242. PubMed: 16857942.
-
(2006)
Science
, vol.313
, pp. 367-370
-
-
Selmecki, A.1
Forche, A.2
Berman, J.3
-
64
-
-
49049118494
-
Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy
-
doi:10.1186/gb-2008-9-7-r115. PubMed: 18638379
-
Ubeda JM, Légaré D, Raymond F, Ouameur AA, Boisvert S et al. (2008) Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy. Genome Biol 9: R115. doi:10.1186/gb-2008-9-7-r115. PubMed: 18638379.
-
(2008)
Genome Biol
, vol.9
-
-
Ubeda, J.M.1
Légaré, D.2
Raymond, F.3
Ouameur, A.A.4
Boisvert, S.5
-
65
-
-
34548131710
-
Effects of aneuploidy on cellular physiology and cell division in haploid yeast
-
doi:10.1126/science.1142210. PubMed: 17702937
-
Torres EM, Sokolsky T, Tucker CM, Chan LY, Boselli M et al. (2007) Effects of aneuploidy on cellular physiology and cell division in haploid yeast. Science 317: 916-924. doi:10.1126/science.1142210. PubMed: 17702937.
-
(2007)
Science
, vol.317
, pp. 916-924
-
-
Torres, E.M.1
Sokolsky, T.2
Tucker, C.M.3
Chan, L.Y.4
Boselli, M.5
-
66
-
-
0035884996
-
Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines
-
PubMed: 11544330
-
Pathak MK, Yi T (2001) Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines. J Immunol 167: 3391-3397. PubMed: 11544330.
-
(2001)
J Immunol
, vol.167
, pp. 3391-3397
-
-
Pathak, M.K.1
Yi, T.2
-
67
-
-
84883371716
-
Identification of antimony resistance markers in Leishmania tropica field isolates through a cDNA-AFLP approach
-
doi:10.1016/j.exppara.2013.07.018. PubMed: 23928349
-
Kazemi-Rad E, Mohebali M, Khadem-Erfan MB, Saffari M, Raoofian R et al. (2013) Identification of antimony resistance markers in Leishmania tropica field isolates through a cDNA-AFLP approach. Exp Parasitol 135: 344-349. doi:10.1016/j.exppara.2013.07.018. PubMed: 23928349.
-
(2013)
Exp Parasitol
, vol.135
, pp. 344-349
-
-
Kazemi-Rad, E.1
Mohebali, M.2
Khadem-Erfan, M.B.3
Saffari, M.4
Raoofian, R.5
-
68
-
-
84455173162
-
Downregulation of mitogen-activated protein kinase 1 of Leishmania donovani field isolates is associated with antimony resistance
-
doi:10.1128/AAC.00736-11. PubMed: 22064540
-
Ashutosh, Garg M, Sundar S, Duncan R, Nakhasi HL et al. (2012) Downregulation of mitogen-activated protein kinase 1 of Leishmania donovani field isolates is associated with antimony resistance. Antimicrob Agents Chemother 56: 518-525. doi:10.1128/AAC.00736-11. PubMed: 22064540.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 518-525
-
-
Ashutosh1
Garg, M.2
Sundar, S.3
Duncan, R.4
Nakhasi, H.L.5
|