-
1
-
-
84861665791
-
Leishmaniasis worldwide and global estimates of its incidence
-
Alvar, J., Velez, I.D., Bern, C., Herrero, M., Desjeux, P., Cano, J., etal. (2012) Leishmaniasis worldwide and global estimates of its incidence. PLoS ONE 7: e35671.
-
(2012)
PLoS ONE
, vol.7
-
-
Alvar, J.1
Velez, I.D.2
Bern, C.3
Herrero, M.4
Desjeux, P.5
Cano, J.6
-
2
-
-
75549088870
-
TriTrypDB: a functional genomic resource for the Trypanosomatidae
-
Aslett, M., Aurrecoechea, C., Berriman, M., Brestelli, J., Brunk, B.P., Carrington, M., etal. (2010) TriTrypDB: a functional genomic resource for the Trypanosomatidae. Nucleic Acids Res 38: D457-D462.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Aslett, M.1
Aurrecoechea, C.2
Berriman, M.3
Brestelli, J.4
Brunk, B.P.5
Carrington, M.6
-
3
-
-
0026072572
-
Gene amplification in Leishmania
-
Beverley, S.M. (1991) Gene amplification in Leishmania. Annu Rev Microbiol 45: 417-444.
-
(1991)
Annu Rev Microbiol
, vol.45
, pp. 417-444
-
-
Beverley, S.M.1
-
4
-
-
79960964869
-
Molecular mechanisms generating and stabilizing terminal 22q13 deletions in 44 subjects with Phelan/McDermid syndrome
-
Bonaglia, M.C., Giorda, R., Beri, S., Agostini, C.D., Novara, F., Fichera, M., etal. (2011) Molecular mechanisms generating and stabilizing terminal 22q13 deletions in 44 subjects with Phelan/McDermid syndrome. PLoS Genet 7: e1002173.
-
(2011)
PLoS Genet
, vol.7
-
-
Bonaglia, M.C.1
Giorda, R.2
Beri, S.3
Agostini, C.D.4
Novara, F.5
Fichera, M.6
-
5
-
-
0141994732
-
Antimony uptake systems in the protozoan parasite Leishmania and accumulation differences in antimony-resistant parasites
-
Brochu, C., Wang, J., Roy, G., Messier, N., Wang, X.Y., Saravia, N.G., and Ouellette, M. (2003) Antimony uptake systems in the protozoan parasite Leishmania and accumulation differences in antimony-resistant parasites. Antimicrob Agents Chemother 47: 3073-3079.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 3073-3079
-
-
Brochu, C.1
Wang, J.2
Roy, G.3
Messier, N.4
Wang, X.Y.5
Saravia, N.G.6
Ouellette, M.7
-
6
-
-
58149218240
-
High-resolution mapping of copy-number alterations with massively parallel sequencing
-
Chiang, D.Y., Getz, G., Jaffe, D.B., O'Kelly, M.J., Zhao, X., Carter, S.L., etal. (2009) High-resolution mapping of copy-number alterations with massively parallel sequencing. Nat Methods 6: 99-103.
-
(2009)
Nat Methods
, vol.6
, pp. 99-103
-
-
Chiang, D.Y.1
Getz, G.2
Jaffe, D.B.3
O'Kelly, M.J.4
Zhao, X.5
Carter, S.L.6
-
7
-
-
84857860666
-
Multiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencing
-
Coelho, A.C., Boisvert, S., Mukherjee, A., Leprohon, P., Corbeil, J., and Ouellette, M. (2012) Multiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencing. PLoS Negl Trop Dis 6: e1512.
-
(2012)
PLoS Negl Trop Dis
, vol.6
-
-
Coelho, A.C.1
Boisvert, S.2
Mukherjee, A.3
Leprohon, P.4
Corbeil, J.5
Ouellette, M.6
-
8
-
-
62149135922
-
Inhibition of Trypanosoma brucei glucose-6-phosphate dehydrogenase by human steroids and their effects on the viability of cultured parasites
-
Cordeiro, A.T., Thiemann, O.H., and Michels, P.A. (2009) Inhibition of Trypanosoma brucei glucose-6-phosphate dehydrogenase by human steroids and their effects on the viability of cultured parasites. Bioorg Med Chem 17: 2483-2489.
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 2483-2489
-
-
Cordeiro, A.T.1
Thiemann, O.H.2
Michels, P.A.3
-
9
-
-
27644513649
-
Gene expression analysis of the mechanism of natural Sb(V) resistance in Leishmania donovani isolates from Nepal
-
Decuypere, S., Rijal, S., Yardley, V., Doncker, S.D., Laurent, T., Khanal, B., etal. (2005) Gene expression analysis of the mechanism of natural Sb(V) resistance in Leishmania donovani isolates from Nepal. Antimicrob Agents Chemother 49: 4616-4621.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 4616-4621
-
-
Decuypere, S.1
Rijal, S.2
Yardley, V.3
Doncker, S.D.4
Laurent, T.5
Khanal, B.6
-
10
-
-
84857852404
-
Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background
-
Decuypere, S., Vanaerschot, M., Brunker, K., Imamura, H., Muller, S., Khanal, B., etal. (2012) Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background. PLoS Negl Trop Dis 6: e1514.
-
(2012)
PLoS Negl Trop Dis
, vol.6
-
-
Decuypere, S.1
Vanaerschot, M.2
Brunker, K.3
Imamura, H.4
Muller, S.5
Khanal, B.6
-
11
-
-
83055168329
-
Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance
-
Downing, T., Imamura, H., Decuypere, S., Clark, T.G., Coombs, G.H., Cotton, J.A., etal. (2011) Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance. Genome Res 21: 2143-2156.
-
(2011)
Genome Res
, vol.21
, pp. 2143-2156
-
-
Downing, T.1
Imamura, H.2
Decuypere, S.3
Clark, T.G.4
Coombs, G.H.5
Cotton, J.A.6
-
12
-
-
0032990769
-
Stage-specific activity of pentavalent antimony against Leishmania donovani axenic amastigotes
-
Ephros, M., Bitnun, A., Shaked, P., Waldman, E., and Zilberstein, D. (1999) Stage-specific activity of pentavalent antimony against Leishmania donovani axenic amastigotes. Antimicrob Agents Chemother 43: 278-282.
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 278-282
-
-
Ephros, M.1
Bitnun, A.2
Shaked, P.3
Waldman, E.4
Zilberstein, D.5
-
13
-
-
43349103776
-
Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes
-
Glover, L., McCulloch, R., and Horn, D. (2008) Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes. Nucleic Acids Res 36: 2608-2618.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 2608-2618
-
-
Glover, L.1
McCulloch, R.2
Horn, D.3
-
14
-
-
79952352962
-
Microhomology-mediated deletion and gene conversion in African trypanosomes
-
Glover, L., Jun, J., and Horn, D. (2011) Microhomology-mediated deletion and gene conversion in African trypanosomes. Nucleic Acids Res 39: 1372-1380.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 1372-1380
-
-
Glover, L.1
Jun, J.2
Horn, D.3
-
15
-
-
3843084085
-
Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin
-
Gourbal, B., Sonuc, N., Bhattacharjee, H., Legare, D., Sundar, S., Ouellette, M., etal. (2004) Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin. J Biol Chem 279: 31010-31017.
-
(2004)
J Biol Chem
, vol.279
, pp. 31010-31017
-
-
Gourbal, B.1
Sonuc, N.2
Bhattacharjee, H.3
Legare, D.4
Sundar, S.5
Ouellette, M.6
-
16
-
-
0027157185
-
Homologous recombination between direct repeat sequences yields P-glycoprotein containing amplicons in arsenite resistant Leishmania
-
Grondin, K., Papadopoulou, B., and Ouellette, M. (1993) Homologous recombination between direct repeat sequences yields P-glycoprotein containing amplicons in arsenite resistant Leishmania. Nucleic Acids Res 21: 1895-1901.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 1895-1901
-
-
Grondin, K.1
Papadopoulou, B.2
Ouellette, M.3
-
17
-
-
0029975465
-
Formation of extrachromosomal circular amplicons with direct or inverted duplications in drug-resistant Leishmania tarentolae
-
Grondin, K., Roy, G., and Ouellette, M. (1996) Formation of extrachromosomal circular amplicons with direct or inverted duplications in drug-resistant Leishmania tarentolae. Mol Cell Biol 16: 3587-3595.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 3587-3595
-
-
Grondin, K.1
Roy, G.2
Ouellette, M.3
-
18
-
-
0030924243
-
Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae
-
Grondin, K., Haimeur, A., Mukhopadhyay, R., Rosen, B.P., and Ouellette, M. (1997) Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae. EMBO J 16: 3057-3065.
-
(1997)
EMBO J
, vol.16
, pp. 3057-3065
-
-
Grondin, K.1
Haimeur, A.2
Mukhopadhyay, R.3
Rosen, B.P.4
Ouellette, M.5
-
19
-
-
0034732687
-
Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (SbIII) resistant Leishmania tarentolae
-
Haimeur, A., Brochu, C., Genest, P., Papadopoulou, B., and Ouellette, M. (2000) Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (SbIII) resistant Leishmania tarentolae. Mol Biochem Parasitol 108: 131-135.
-
(2000)
Mol Biochem Parasitol
, vol.108
, pp. 131-135
-
-
Haimeur, A.1
Brochu, C.2
Genest, P.3
Papadopoulou, B.4
Ouellette, M.5
-
20
-
-
59249105978
-
A microhomology-mediated break-induced replication model for the origin of human copy number variation
-
Hastings, P.J., Ira, G., and Lupski, J.R. (2009) A microhomology-mediated break-induced replication model for the origin of human copy number variation. PLoS Genet 5: e1000327.
-
(2009)
PLoS Genet
, vol.5
-
-
Hastings, P.J.1
Ira, G.2
Lupski, J.R.3
-
21
-
-
22244437571
-
The genome of the kinetoplastid parasite, Leishmania major
-
Ivens, A.C., Peacock, C.S., Worthey, E.A., Murphy, L., Aggarwal, G., Berriman, M., etal. (2005) The genome of the kinetoplastid parasite, Leishmania major. Science 309: 436-442.
-
(2005)
Science
, vol.309
, pp. 436-442
-
-
Ivens, A.C.1
Peacock, C.S.2
Worthey, E.A.3
Murphy, L.4
Aggarwal, G.5
Berriman, M.6
-
22
-
-
0033540005
-
Miltefosine, an oral agent, for the treatment of Indian visceral leishmaniasis
-
Jha, T.K., Sundar, S., Thakur, C.P., Bachmann, P., Karbwang, J., Fischer, C., etal. (1999) Miltefosine, an oral agent, for the treatment of Indian visceral leishmaniasis. N Engl J Med 341: 1795-1800.
-
(1999)
N Engl J Med
, vol.341
, pp. 1795-1800
-
-
Jha, T.K.1
Sundar, S.2
Thakur, C.P.3
Bachmann, P.4
Karbwang, J.5
Fischer, C.6
-
23
-
-
69649109364
-
Circos: an information aesthetic for comparative genomics
-
Krzywinski, M., Schein, J., Birol, I., Connors, J., Gascoyne, R., Horsman, D., etal. (2009) Circos: an information aesthetic for comparative genomics. Genome Res 19: 1639-1645.
-
(2009)
Genome Res
, vol.19
, pp. 1639-1645
-
-
Krzywinski, M.1
Schein, J.2
Birol, I.3
Connors, J.4
Gascoyne, R.5
Horsman, D.6
-
24
-
-
84862771688
-
Biomarkers of antimony resistance: need for expression analysis of multiple genes to distinguish resistance phenotype in clinical isolates of Leishmania donovani
-
Kumar, D., Singh, R., Bhandari, V., Kulshrestha, A., Negi, N.S., and Salotra, P. (2012) Biomarkers of antimony resistance: need for expression analysis of multiple genes to distinguish resistance phenotype in clinical isolates of Leishmania donovani. Parasitol Res 111: 223-230.
-
(2012)
Parasitol Res
, vol.111
, pp. 223-230
-
-
Kumar, D.1
Singh, R.2
Bhandari, V.3
Kulshrestha, A.4
Negi, N.S.5
Salotra, P.6
-
25
-
-
0036144405
-
Programmed cell death in the unicellular protozoan parasite Leishmania
-
Lee, N., Bertholet, S., Debrabant, A., Muller, J., Duncan, R., and Nakhasi, H.L. (2002) Programmed cell death in the unicellular protozoan parasite Leishmania. Cell Death Differ 9: 53-64.
-
(2002)
Cell Death Differ
, vol.9
, pp. 53-64
-
-
Lee, N.1
Bertholet, S.2
Debrabant, A.3
Muller, J.4
Duncan, R.5
Nakhasi, H.L.6
-
26
-
-
0035854830
-
The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase
-
Legare, D., Richard, D., Mukhopadhyay, R., Stierhof, Y.D., Rosen, B.P., Haimeur, A., etal. (2001) The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase. J Biol Chem 276: 26301-26307.
-
(2001)
J Biol Chem
, vol.276
, pp. 26301-26307
-
-
Legare, D.1
Richard, D.2
Mukhopadhyay, R.3
Stierhof, Y.D.4
Rosen, B.P.5
Haimeur, A.6
-
27
-
-
63249133197
-
Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum
-
Leprohon, P., Legare, D., Raymond, F., Madore, E., Hardiman, G., Corbeil, J., and Ouellette, M. (2009) Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum. Nucleic Acids Res 37: 1387-1399.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1387-1399
-
-
Leprohon, P.1
Legare, D.2
Raymond, F.3
Madore, E.4
Hardiman, G.5
Corbeil, J.6
Ouellette, M.7
-
28
-
-
77949587649
-
Fast and accurate long-read alignment with Burrows-Wheeler transform
-
Li, H., and Durbin, R. (2010) Fast and accurate long-read alignment with Burrows-Wheeler transform. Bioinformatics 26: 589-595.
-
(2010)
Bioinformatics
, vol.26
, pp. 589-595
-
-
Li, H.1
Durbin, R.2
-
29
-
-
55549097836
-
Mapping short DNA sequencing reads and calling variants using mapping quality scores
-
Li, H., Ruan, J., and Durbin, R. (2008) Mapping short DNA sequencing reads and calling variants using mapping quality scores. Genome Res 18: 1851-1858.
-
(2008)
Genome Res
, vol.18
, pp. 1851-1858
-
-
Li, H.1
Ruan, J.2
Durbin, R.3
-
30
-
-
68549104404
-
The sequence alignment/map format and SAMtools
-
Li, H., Handsaker, B., Wysoker, A., Fennell, T., Ruan, J., Homer, N., etal. (2009) The sequence alignment/map format and SAMtools. Bioinformatics 25: 2078-2079.
-
(2009)
Bioinformatics
, vol.25
, pp. 2078-2079
-
-
Li, H.1
Handsaker, B.2
Wysoker, A.3
Fennell, T.4
Ruan, J.5
Homer, N.6
-
31
-
-
0033509735
-
Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani
-
Lira, R., Sundar, S., Makharia, A., Kenney, R., Gam, A., Saraiva, E., and Sacks, D. (1999) Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani. J Infect Dis 180: 564-567.
-
(1999)
J Infect Dis
, vol.180
, pp. 564-567
-
-
Lira, R.1
Sundar, S.2
Makharia, A.3
Kenney, R.4
Gam, A.5
Saraiva, E.6
Sacks, D.7
-
32
-
-
77950336943
-
Assessing aquaglyceroporin gene status and expression profile in antimony-susceptible and -resistant clinical isolates of Leishmania donovani from India
-
Mandal, S., Maharjan, M., Singh, S., Chatterjee, M., and Madhubala, R. (2010) Assessing aquaglyceroporin gene status and expression profile in antimony-susceptible and -resistant clinical isolates of Leishmania donovani from India. J Antimicrob Chemother 65: 496-507.
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 496-507
-
-
Mandal, S.1
Maharjan, M.2
Singh, S.3
Chatterjee, M.4
Madhubala, R.5
-
33
-
-
25144440472
-
Modulation in aquaglyceroporin AQP1 gene transcript levels in drug-resistant Leishmania
-
Marquis, N., Gourbal, B., Rosen, B.P., Mukhopadhyay, R., and Ouellette, M. (2005) Modulation in aquaglyceroporin AQP1 gene transcript levels in drug-resistant Leishmania. Mol Microbiol 57: 1690-1699.
-
(2005)
Mol Microbiol
, vol.57
, pp. 1690-1699
-
-
Marquis, N.1
Gourbal, B.2
Rosen, B.P.3
Mukhopadhyay, R.4
Ouellette, M.5
-
35
-
-
0027325817
-
Telomere capture stabilizes chromosome breakage
-
Meltzer, P.S., Guan, X.Y., and Trent, J.M. (1993) Telomere capture stabilizes chromosome breakage. Nat Genet 4: 252-255.
-
(1993)
Nat Genet
, vol.4
, pp. 252-255
-
-
Meltzer, P.S.1
Guan, X.Y.2
Trent, J.M.3
-
36
-
-
34249747773
-
Characterization of natural antimony resistance in Leishmania donovani isolates
-
Mittal, M.K., Rai, S., Ravinder, A., Gupta, S., Sundar, S., and Goyal, N. (2007) Characterization of natural antimony resistance in Leishmania donovani isolates. Am J Trop Med Hyg 76: 681-688.
-
(2007)
Am J Trop Med Hyg
, vol.76
, pp. 681-688
-
-
Mittal, M.K.1
Rai, S.2
Ravinder, A.3
Gupta, S.4
Sundar, S.5
Goyal, N.6
-
37
-
-
33646456171
-
Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinase and mitogen-activated protein kinase activation in Leishmania donovani-infected macrophages
-
Mookerjee Basu, J., Mookerjee, A., Sen, P., Bhaumik, S., Banerjee, S., Naskar, K., etal. (2006) Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinase and mitogen-activated protein kinase activation in Leishmania donovani-infected macrophages. Antimicrob Agents Chemother 50: 1788-1797.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 1788-1797
-
-
Mookerjee Basu, J.1
Mookerjee, A.2
Sen, P.3
Bhaumik, S.4
Banerjee, S.5
Naskar, K.6
-
38
-
-
80053395366
-
Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania
-
Moreira, W., Leprohon, P., and Ouellette, M. (2011) Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania. Cell Death Dis 2: e201.
-
(2011)
Cell Death Dis
, vol.2
-
-
Moreira, W.1
Leprohon, P.2
Ouellette, M.3
-
39
-
-
33947528405
-
Role of ABC transporter MRPA, gamma-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani
-
Mukherjee, A., Padmanabhan, P.K., Singh, S., Roy, G., Girard, I., Chatterjee, M., etal. (2007) Role of ABC transporter MRPA, gamma-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani. J Antimicrob Chemother 59: 204-211.
-
(2007)
J Antimicrob Chemother
, vol.59
, pp. 204-211
-
-
Mukherjee, A.1
Padmanabhan, P.K.2
Singh, S.3
Roy, G.4
Girard, I.5
Chatterjee, M.6
-
40
-
-
70449562301
-
The gamma-glutamylcysteine synthetase gene of Leishmania is essential and involved in response to oxidants
-
Mukherjee, A., Roy, G., Guimond, C., and Ouellette, M. (2009) The gamma-glutamylcysteine synthetase gene of Leishmania is essential and involved in response to oxidants. Mol Microbiol 74: 914-927.
-
(2009)
Mol Microbiol
, vol.74
, pp. 914-927
-
-
Mukherjee, A.1
Roy, G.2
Guimond, C.3
Ouellette, M.4
-
41
-
-
80053210398
-
Intrachromosomal tandem duplication and repeat expansion during attempts to inactivate the subtelomeric essential gene GSH1 in Leishmania
-
Mukherjee, A., Langston, L.D., and Ouellette, M. (2011) Intrachromosomal tandem duplication and repeat expansion during attempts to inactivate the subtelomeric essential gene GSH1 in Leishmania. Nucleic Acids Res 39: 7499-7511.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 7499-7511
-
-
Mukherjee, A.1
Langston, L.D.2
Ouellette, M.3
-
42
-
-
33745264366
-
The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks
-
Narayanan, V., Mieczkowski, P.A., Kim, H.M., Petes, T.D., and Lobachev, K.S. (2006) The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks. Cell 125: 1283-1296.
-
(2006)
Cell
, vol.125
, pp. 1283-1296
-
-
Narayanan, V.1
Mieczkowski, P.A.2
Kim, H.M.3
Petes, T.D.4
Lobachev, K.S.5
-
43
-
-
0025321675
-
The amplified H circle of methotrexate-resistant leishmania tarentolae contains a novel P-glycoprotein gene
-
Ouellette, M., Fase-Fowler, F., and Borst, P. (1990) The amplified H circle of methotrexate-resistant leishmania tarentolae contains a novel P-glycoprotein gene. EMBO J 9: 1027-1033.
-
(1990)
EMBO J
, vol.9
, pp. 1027-1033
-
-
Ouellette, M.1
Fase-Fowler, F.2
Borst, P.3
-
44
-
-
0026022969
-
Direct and inverted DNA repeats associated with P-glycoprotein gene amplification in drug resistant Leishmania
-
Ouellette, M., Hettema, E., Wust, D., Fase-Fowler, F., and Borst, P. (1991) Direct and inverted DNA repeats associated with P-glycoprotein gene amplification in drug resistant Leishmania. EMBO J 10: 1009-1016.
-
(1991)
EMBO J
, vol.10
, pp. 1009-1016
-
-
Ouellette, M.1
Hettema, E.2
Wust, D.3
Fase-Fowler, F.4
Borst, P.5
-
45
-
-
77955295646
-
Ascorbate peroxidase from Leishmania major controls the virulence of infective stage of promastigotes by regulating oxidative stress
-
Pal, S., Dolai, S., Yadav, R.K., and Adak, S. (2010) Ascorbate peroxidase from Leishmania major controls the virulence of infective stage of promastigotes by regulating oxidative stress. PLoS ONE 5: e11271.
-
(2010)
PLoS ONE
, vol.5
-
-
Pal, S.1
Dolai, S.2
Yadav, R.K.3
Adak, S.4
-
46
-
-
40649091062
-
Vaccines for leishmaniasis in the fore coming 25 years
-
Palatnik-de-Sousa, C.B. (2008) Vaccines for leishmaniasis in the fore coming 25 years. Vaccine 26: 1709-1724.
-
(2008)
Vaccine
, vol.26
, pp. 1709-1724
-
-
Palatnik-de-Sousa, C.B.1
-
47
-
-
0026779424
-
A novel antifolate resistance gene on the amplified H circle of Leishmania
-
Papadopoulou, B., Roy, G., and Ouellette, M. (1992) A novel antifolate resistance gene on the amplified H circle of Leishmania. EMBO J 11: 3601-3608.
-
(1992)
EMBO J
, vol.11
, pp. 3601-3608
-
-
Papadopoulou, B.1
Roy, G.2
Ouellette, M.3
-
48
-
-
62449137037
-
Formation of new chromosomes as a virulence mechanism in yeast Candida glabrata
-
Polakova, S., Blume, C., Zarate, J.A., Mentel, M., Jorck-Ramberg, D., Stenderup, J., and Piskur, J. (2009) Formation of new chromosomes as a virulence mechanism in yeast Candida glabrata. Proc Natl Acad Sci USA 106: 2688-2693.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2688-2693
-
-
Polakova, S.1
Blume, C.2
Zarate, J.A.3
Mentel, M.4
Jorck-Ramberg, D.5
Stenderup, J.6
Piskur, J.7
-
49
-
-
11144233245
-
Growth phase regulation of the main folate transporter of Leishmania infantum and its role in methotrexate resistance
-
Richard, D., Leprohon, P., Drummelsmith, J., and Ouellette, M. (2004) Growth phase regulation of the main folate transporter of Leishmania infantum and its role in methotrexate resistance. J Biol Chem 279: 54494-54501.
-
(2004)
J Biol Chem
, vol.279
, pp. 54494-54501
-
-
Richard, D.1
Leprohon, P.2
Drummelsmith, J.3
Ouellette, M.4
-
50
-
-
0029031644
-
In vitro antileishmanial properties of tri- and pentavalent antimonial preparations
-
Roberts, W.L., Berman, J.D., and Rainey, P.M. (1995) In vitro antileishmanial properties of tri- and pentavalent antimonial preparations. Antimicrob Agents Chemother 39: 1234-1239.
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 1234-1239
-
-
Roberts, W.L.1
Berman, J.D.2
Rainey, P.M.3
-
51
-
-
83055181962
-
Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania
-
Rogers, M.B., Hilley, J.D., Dickens, N.J., Wilkes, J., Bates, P.A., Depledge, D.P., etal. (2011) Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania. Genome Res 21: 2129-2142.
-
(2011)
Genome Res
, vol.21
, pp. 2129-2142
-
-
Rogers, M.B.1
Hilley, J.D.2
Dickens, N.J.3
Wilkes, J.4
Bates, P.A.5
Depledge, D.P.6
-
53
-
-
33746506280
-
Aneuploidy and isochromosome formation in drug-resistant Candida albicans
-
Selmecki, A., Forche, A., and Berman, J. (2006) Aneuploidy and isochromosome formation in drug-resistant Candida albicans. Science 313: 367-370.
-
(2006)
Science
, vol.313
, pp. 367-370
-
-
Selmecki, A.1
Forche, A.2
Berman, J.3
-
54
-
-
0031760626
-
Axenically grown amastigotes of Leishmania infantum used as an in vitro model to investigate the pentavalent antimony mode of action
-
Sereno, D., Cavaleyra, M., Zemzoumi, K., Maquaire, S., Ouaissi, A., and Lemesre, J.L. (1998) Axenically grown amastigotes of Leishmania infantum used as an in vitro model to investigate the pentavalent antimony mode of action. Antimicrob Agents Chemother 42: 3097-3102.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 3097-3102
-
-
Sereno, D.1
Cavaleyra, M.2
Zemzoumi, K.3
Maquaire, S.4
Ouaissi, A.5
Lemesre, J.L.6
-
55
-
-
0034950111
-
Antimonial-mediated DNA fragmentation in Leishmania infantum amastigotes
-
Sereno, D., Holzmuller, P., Mangot, I., Cuny, G., Ouaissi, A., and Lemesre, J.L. (2001) Antimonial-mediated DNA fragmentation in Leishmania infantum amastigotes. Antimicrob Agents Chemother 45: 2064-2069.
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 2064-2069
-
-
Sereno, D.1
Holzmuller, P.2
Mangot, I.3
Cuny, G.4
Ouaissi, A.5
Lemesre, J.L.6
-
56
-
-
0035830909
-
Novel Intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani
-
Shaked-Mishan, P., Ulrich, N., Ephros, M., and Zilberstein, D. (2001) Novel Intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani. J Biol Chem 276: 3971-3976.
-
(2001)
J Biol Chem
, vol.276
, pp. 3971-3976
-
-
Shaked-Mishan, P.1
Ulrich, N.2
Ephros, M.3
Zilberstein, D.4
-
57
-
-
4544341015
-
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
-
Smyth, G.K. (2004) Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3: Article3.
-
(2004)
Stat Appl Genet Mol Biol
, vol.3
-
-
Smyth, G.K.1
-
58
-
-
0242333835
-
Normalization of cDNA microarray data
-
Smyth, G.K., and Speed, T. (2003) Normalization of cDNA microarray data. Methods 31: 265-273.
-
(2003)
Methods
, vol.31
, pp. 265-273
-
-
Smyth, G.K.1
Speed, T.2
-
59
-
-
18744369640
-
Use of within-array replicate spots for assessing differential expression in microarray experiments
-
Smyth, G.K., Michaud, J., and Scott, H.S. (2005) Use of within-array replicate spots for assessing differential expression in microarray experiments. Bioinformatics 21: 2067-2075.
-
(2005)
Bioinformatics
, vol.21
, pp. 2067-2075
-
-
Smyth, G.K.1
Michaud, J.2
Scott, H.S.3
-
60
-
-
0042090390
-
2+ through non-selective cation channels in the host and the parasite is responsible for apoptosis of intracellular Leishmania donovani amastigotes
-
2+ through non-selective cation channels in the host and the parasite is responsible for apoptosis of intracellular Leishmania donovani amastigotes. J Biol Chem 278: 25120-25132.
-
(2003)
J Biol Chem
, vol.278
, pp. 25120-25132
-
-
Sudhandiran, G.1
Shaha, C.2
-
61
-
-
0034780949
-
Drug resistance in Indian visceral leishmaniasis
-
Sundar, S. (2001) Drug resistance in Indian visceral leishmaniasis. Trop Med Int Health 6: 849-854.
-
(2001)
Trop Med Int Health
, vol.6
, pp. 849-854
-
-
Sundar, S.1
-
62
-
-
0035853759
-
A telomere-mediated chromosome fragmentation approach to assess mitotic stability and ploidy alterations of Leishmania chromosomes
-
Tamar, S., and Papadopoulou, B. (2001) A telomere-mediated chromosome fragmentation approach to assess mitotic stability and ploidy alterations of Leishmania chromosomes. J Biol Chem 276: 11662-11673.
-
(2001)
J Biol Chem
, vol.276
, pp. 11662-11673
-
-
Tamar, S.1
Papadopoulou, B.2
-
63
-
-
49049118494
-
Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy
-
Ubeda, J.M., Legare, D., Raymond, F., Ouameur, A.A., Boisvert, S., Rigault, P., etal. (2008) Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy. Genome Biol 9: R115.
-
(2008)
Genome Biol
, vol.9
-
-
Ubeda, J.M.1
Legare, D.2
Raymond, F.3
Ouameur, A.A.4
Boisvert, S.5
Rigault, P.6
-
64
-
-
33846554383
-
A proteomics screen implicates HSP83 and a small kinetoplastid calpain-related protein in drug resistance in Leishmania donovani clinical field isolates by modulating drug-induced programmed cell death
-
Vergnes, B., Gourbal, B., Girard, I., Sundar, S., Drummelsmith, J., and Ouellette, M. (2007) A proteomics screen implicates HSP83 and a small kinetoplastid calpain-related protein in drug resistance in Leishmania donovani clinical field isolates by modulating drug-induced programmed cell death. Mol Cell Proteomics 6: 88-101.
-
(2007)
Mol Cell Proteomics
, vol.6
, pp. 88-101
-
-
Vergnes, B.1
Gourbal, B.2
Girard, I.3
Sundar, S.4
Drummelsmith, J.5
Ouellette, M.6
-
65
-
-
0025007621
-
A truncated human chromosome 16 associated with alpha thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n
-
Wilkie, A.O., Lamb, J., Harris, P.C., Finney, R.D., and Higgs, D.R. (1990) A truncated human chromosome 16 associated with alpha thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n. Nature 346: 868-871.
-
(1990)
Nature
, vol.346
, pp. 868-871
-
-
Wilkie, A.O.1
Lamb, J.2
Harris, P.C.3
Finney, R.D.4
Higgs, D.R.5
-
66
-
-
42049091432
-
Roles of trypanothione S-transferase and tryparedoxin peroxidase in resistance to antimonials
-
Wyllie, S., Vickers, T.J., and Fairlamb, A.H. (2008) Roles of trypanothione S-transferase and tryparedoxin peroxidase in resistance to antimonials. Antimicrob Agents Chemother 52: 1359-1365.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 1359-1365
-
-
Wyllie, S.1
Vickers, T.J.2
Fairlamb, A.H.3
-
67
-
-
77954761899
-
Elevated levels of tryparedoxin peroxidase in antimony unresponsive Leishmania donovani field isolates
-
Wyllie, S., Mandal, G., Singh, N., Sundar, S., Fairlamb, A.H., and Chatterjee, M. (2010) Elevated levels of tryparedoxin peroxidase in antimony unresponsive Leishmania donovani field isolates. Mol Biochem Parasitol 173: 162-164.
-
(2010)
Mol Biochem Parasitol
, vol.173
, pp. 162-164
-
-
Wyllie, S.1
Mandal, G.2
Singh, N.3
Sundar, S.4
Fairlamb, A.H.5
Chatterjee, M.6
-
68
-
-
65549090043
-
Molecular mechanisms for subtelomeric rearrangements associated with the 9q34.3 microdeletion syndrome
-
Yatsenko, S.A., Brundage, E.K., Roney, E.K., Cheung, S.W., Chinault, A.C., and Lupski, J.R. (2009) Molecular mechanisms for subtelomeric rearrangements associated with the 9q34.3 microdeletion syndrome. Hum Mol Genet 18: 1924-1936.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1924-1936
-
-
Yatsenko, S.A.1
Brundage, E.K.2
Roney, E.K.3
Cheung, S.W.4
Chinault, A.C.5
Lupski, J.R.6
|