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Volumn 134, Issue 12, 2007, Pages 1679-1687

Increased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimony

Author keywords

Antimonial resistance; Oxidative stress; Reactive oxygen species; Thiols; Visceral leishmaniasis

Indexed keywords

ANTIMONY; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; THIOL;

EID: 34948899791     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182007003150     Document Type: Article
Times cited : (97)

References (34)
  • 1
    • 0028822932 scopus 로고
    • New mechanisms of drug resistance in parasitic protozoa
    • Borst, P. and Ouellette, M. (1995). New mechanisms of drug resistance in parasitic protozoa. Annual Review of Microbiology 49, 427-460.
    • (1995) Annual Review of Microbiology , vol.49 , pp. 427-460
    • Borst, P.1    Ouellette, M.2
  • 2
    • 0024299411 scopus 로고
    • Mode of action of pentavalent antimonials: Specific inhibition of type I DNA topoisomerase of Leishmania donovani
    • Chakraborty, A. K. and Majumder, H. K. (1988). Mode of action of pentavalent antimonials: specific inhibition of type I DNA topoisomerase of Leishmania donovani. Biochemical and Biophysical Research Communications 152, 605-611.
    • (1988) Biochemical and Biophysical Research Communications , vol.152 , pp. 605-611
    • Chakraborty, A.K.1    Majumder, H.K.2
  • 5
    • 0026793462 scopus 로고
    • Metabolism and functions of trypanothione in the Kinetoplastida
    • Fairlamb, A. H. and Cerami, A. (1992). Metabolism and functions of trypanothione in the Kinetoplastida. Annual Review of Microbiology 46, 695-729.
    • (1992) Annual Review of Microbiology , vol.46 , pp. 695-729
    • Fairlamb, A.H.1    Cerami, A.2
  • 6
    • 0037328022 scopus 로고    scopus 로고
    • Role of superoxide dismutase in survival of Leishmania within the macrophage
    • Ghosh, S., Goswami, S. and Adhya, S. (2003). Role of superoxide dismutase in survival of Leishmania within the macrophage. The Biochemical Journal 369, 447-452.
    • (2003) The Biochemical Journal , vol.369 , pp. 447-452
    • Ghosh, S.1    Goswami, S.2    Adhya, S.3
  • 7
    • 0036176510 scopus 로고    scopus 로고
    • Mechanisms of cancer drug resistance
    • Gottesman, M. M. (2002). Mechanisms of cancer drug resistance. Annual Review of Medicine 53, 615-627.
    • (2002) Annual Review of Medicine , vol.53 , pp. 615-627
    • Gottesman, M.M.1
  • 8
    • 0018666729 scopus 로고
    • Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)
    • Griffith, O. W. and Meister, A. (1979). Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). Journal of Biological Chemistry 254, 7558-7560.
    • (1979) Journal of Biological Chemistry , vol.254 , pp. 7558-7560
    • Griffith, O.W.1    Meister, A.2
  • 9
    • 0030924243 scopus 로고    scopus 로고
    • Coamplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite resistant Leishmania tarentolae
    • Grondin, K., Haimeur, A., Mukhopadhyay, R., Rosen, B. P. and Ouellette, M. (1997). Coamplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite resistant Leishmania tarentolae. EMBO Journal 16, 3057-3065.
    • (1997) EMBO Journal , vol.16 , pp. 3057-3065
    • Grondin, K.1    Haimeur, A.2    Mukhopadhyay, R.3    Rosen, B.P.4    Ouellette, M.5
  • 11
    • 0034732687 scopus 로고    scopus 로고
    • Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (Sb III) resistant Leishmania tarentolae
    • Haimeur, A., Brochu, C., Genest, P., Papadopoulou, B. and Ouellette, M. (2000). Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (Sb III) resistant Leishmania tarentolae. Molecular and Biochemical Parasitology 108, 131-135.
    • (2000) Molecular and Biochemical Parasitology , vol.108 , pp. 131-135
    • Haimeur, A.1    Brochu, C.2    Genest, P.3    Papadopoulou, B.4    Ouellette, M.5
  • 12
    • 0032744407 scopus 로고    scopus 로고
    • Elevated levels of polyamines and trypanothione resulting from overexpression of the ornithine decarboxylase gene in arsenite resistant Leishmania
    • Haimeur, A., Guimond, C., Pilote, S., Mukhopadhyay, R., Rosen, B. P., Poulin, R. and Ouellette, M. (1999). Elevated levels of polyamines and trypanothione resulting from overexpression of the ornithine decarboxylase gene in arsenite resistant Leishmania. Molecular Microbiology 34, 726-735.
    • (1999) Molecular Microbiology , vol.34 , pp. 726-735
    • Haimeur, A.1    Guimond, C.2    Pilote, S.3    Mukhopadhyay, R.4    Rosen, B.P.5    Poulin, R.6    Ouellette, M.7
  • 13
    • 0033517487 scopus 로고    scopus 로고
    • Leishmaniasis
    • Herwaldt, B. L. (1999). Leishmaniasis. Lancet 354, 1191-1199.
    • (1999) Lancet , vol.354 , pp. 1191-1199
    • Herwaldt, B.L.1
  • 15
    • 0347755366 scopus 로고    scopus 로고
    • Reversing agents for ATP-binding cassette (ABC) transporters: Application in modulating multidrug resistance (MDR)
    • Lee, C. W. (2004). Reversing agents for ATP-binding cassette (ABC) transporters: application in modulating multidrug resistance (MDR). Current Medicinal Chemistry Anti-Cancer Agents 4, 43-52.
    • (2004) Current Medicinal Chemistry Anti-Cancer Agents , vol.4 , pp. 43-52
    • Lee, C.W.1
  • 17
    • 25144440472 scopus 로고    scopus 로고
    • Modulation in aquaglyceroporin AQP1 gene transcript levels in drug-resistant Leishmania
    • Marquis, N., Gourbal, B., Rosen, B. P., Mukhopadhyay, R. and Ouellette, M. (2005). Modulation in aquaglyceroporin AQP1 gene transcript levels in drug-resistant Leishmania. Molecular Microbiology 57, 1690-1699.
    • (2005) Molecular Microbiology , vol.57 , pp. 1690-1699
    • Marquis, N.1    Gourbal, B.2    Rosen, B.P.3    Mukhopadhyay, R.4    Ouellette, M.5
  • 20
    • 33646456171 scopus 로고    scopus 로고
    • Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinase and mitogen-activated protein kinase activation in Leishmania donovani-infected macrophages
    • Mookerjee Basu, J., Mookerjee, A., Sen, P., Bhaumik, S., Sen, P., Banerjee, S., Naskar, K., Choudhuri, S. K., Saha, B., Raha, S. and Roy, S. (2006). Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinase and mitogen-activated protein kinase activation in Leishmania donovani-infected macrophages. Antimicrobial Agents and Chemotherapy 50, 1788-1797.
    • (2006) Antimicrobial Agents and Chemotherapy , vol.50 , pp. 1788-1797
    • Mookerjee Basu, J.1    Mookerjee, A.2    Sen, P.3    Bhaumik, S.4    Sen, P.5    Banerjee, S.6    Naskar, K.7    Choudhuri, S.K.8    Saha, B.9    Raha, S.10    Roy, S.11
  • 21
    • 33947528405 scopus 로고    scopus 로고
    • Role of ABC transporter MRPA, γ-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani
    • Mukherjee, A., Prasad, K. P., Singh, S., Roy, G., Girard, I., Chatterjee, M., Ouellette, M. and Madhubala, R. (2007). Role of ABC transporter MRPA, γ-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani. Journal of Antimicrobial Chemotherapy 59, 204-211.
    • (2007) Journal of Antimicrobial Chemotherapy , vol.59 , pp. 204-211
    • Mukherjee, A.1    Prasad, K.P.2    Singh, S.3    Roy, G.4    Girard, I.5    Chatterjee, M.6    Ouellette, M.7    Madhubala, R.8
  • 24
    • 0024119576 scopus 로고
    • A flow cytometric assay for intracellular nonprotein thiols using mercury orange
    • O'Connor, J. E., Kimler, B. F., Morgan, M. C. and Tempas, K. J. (1988). A flow cytometric assay for intracellular nonprotein thiols using mercury orange. Cytometry 9, 529-532.
    • (1988) Cytometry , vol.9 , pp. 529-532
    • O'Connor, J.E.1    Kimler, B.F.2    Morgan, M.C.3    Tempas, K.J.4
  • 25
    • 0025822869 scopus 로고
    • Drug resistance and P-glycoprotein gene amplification in the protozoan parasite Leishmania
    • Ouellette, M. and Borst, P. (1991). Drug resistance and P-glycoprotein gene amplification in the protozoan parasite Leishmania. Research in Microbiology 142, 737-746.
    • (1991) Research in Microbiology , vol.142 , pp. 737-746
    • Ouellette, M.1    Borst, P.2
  • 26
    • 0027320366 scopus 로고
    • Antileishmanial activity of sodium stibogluconate fractions
    • Roberts, W. L. and Rainey, P. M. (1993). Antileishmanial activity of sodium stibogluconate fractions. Antimicrobial Agents and Chemotherapy 37, 1842-1846.
    • (1993) Antimicrobial Agents and Chemotherapy , vol.37 , pp. 1842-1846
    • Roberts, W.L.1    Rainey, P.M.2
  • 27
    • 0031760626 scopus 로고    scopus 로고
    • Axenically grown amastigotes of Leishmania infantum used as an in vitro model to investigate the pentavalent antimony mode of action
    • Sereno, D., Cavaleyra, M., Zemzoumi, K., Maquaire, S., Ouaissi, A. and Lemesre, J. L. (1998). Axenically grown amastigotes of Leishmania infantum used as an in vitro model to investigate the pentavalent antimony mode of action. Antimicrobial Agents and Chemotherapy 42, 3097-3102.
    • (1998) Antimicrobial Agents and Chemotherapy , vol.42 , pp. 3097-3102
    • Sereno, D.1    Cavaleyra, M.2    Zemzoumi, K.3    Maquaire, S.4    Ouaissi, A.5    Lemesre, J.L.6
  • 29
    • 0023832140 scopus 로고
    • Levels of polyamines, glutathione and glutathione-spermidine conjugates during growth of the insect trypanosomatid Crithidia fasciculata
    • Shim, H. and Fairlamb, A. H. (1988). Levels of polyamines, glutathione and glutathione-spermidine conjugates during growth of the insect trypanosomatid Crithidia fasciculata. Journal of General Microbiology 134, 807-817.
    • (1988) Journal of General Microbiology , vol.134 , pp. 807-817
    • Shim, H.1    Fairlamb, A.H.2
  • 30
    • 34248397955 scopus 로고    scopus 로고
    • Differential gene expression analysis in antimony unresponsive Indian kala azar (visceral leishmaniasis) clinical isolates by DNA microarray
    • Singh, N., Almeida, R., Kothari, H., Kumar, P., Mandal, G., Chatterjee, M., Venkatachalam, S., Govind, M. K., Mandal, S. K. and Sundar, S. (2007). Differential gene expression analysis in antimony unresponsive Indian kala azar (visceral leishmaniasis) clinical isolates by DNA microarray. Parasitology 134, 777-787.
    • (2007) Parasitology , vol.134 , pp. 777-787
    • Singh, N.1    Almeida, R.2    Kothari, H.3    Kumar, P.4    Mandal, G.5    Chatterjee, M.6    Venkatachalam, S.7    Govind, M.K.8    Mandal, S.K.9    Sundar, S.10
  • 31
    • 33745224305 scopus 로고    scopus 로고
    • Visceral leishmaniasis - current therapeutic modalities
    • Sundar, S. and Chatterjee, M. (2006). Visceral leishmaniasis - current therapeutic modalities. Indian Journal of Medical Research 123, 345-352.
    • (2006) Indian Journal of Medical Research , vol.123 , pp. 345-352
    • Sundar, S.1    Chatterjee, M.2
  • 32
    • 34948908448 scopus 로고    scopus 로고
    • TDR (2005). Leishmaniasis. Seventeenth Programme Report, Progress 2003-2004, 19-25.
    • TDR (2005). Leishmaniasis. Seventeenth Programme Report, Progress 2003-2004, 19-25.
  • 33
    • 0027417221 scopus 로고
    • An automated micro-fluorometric assay for monitoring oxidative burst activity of phagocytes
    • Wan, C. P., Myung, E. and Lau, B. H. (1993). An automated micro-fluorometric assay for monitoring oxidative burst activity of phagocytes. Journal of Immunological Methods 159, 131-138.
    • (1993) Journal of Immunological Methods , vol.159 , pp. 131-138
    • Wan, C.P.1    Myung, E.2    Lau, B.H.3
  • 34
    • 4544289321 scopus 로고    scopus 로고
    • Dual action of antimonial drugs on thiol redox metabolism in the human pathogen Leishmania donovani
    • Wyllie, S., Cunningham, M. L. and Fairlamb, A. H. (2004). Dual action of antimonial drugs on thiol redox metabolism in the human pathogen Leishmania donovani. Journal of Biological Chemistry 279, 39925-39932.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 39925-39932
    • Wyllie, S.1    Cunningham, M.L.2    Fairlamb, A.H.3


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