Downregulation of mitogen-activated protein kinase 1 of Leishmania donovani field isolates is associated with antimony resistance

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 1, 2012, Pages 518-525

  Ashutosh, ^a   Garg, Mansi ^a   Sundar, Shyam ^b   Duncan, Robert ^c   Nakhasi, Hira L ^c   Goyal, Neena ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b BANARAS HINDU UNIVERSITY   (India)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMONY; ANTIMONY TARTRATE; MITOGEN ACTIVATED PROTEIN KINASE 1; MYELIN BASIC PROTEIN; STAUROSPORINE; STIBOGLUCONATE SODIUM;

ARTICLE; DNA MICROARRAY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME STRUCTURE; ESCHERICHIA COLI; GENE EXPRESSION; KINETOPLAST; LEISHMANIA DONOVANI; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; WESTERN BLOTTING;

ANTIMONY; ANTIPROTOZOAL AGENTS; DOWN-REGULATION; DRUG RESISTANCE; ESCHERICHIA COLI; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INDIA; KINETICS; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MYELIN SHEATH; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARASITIC SENSITIVITY TESTS; PROTOZOAN PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; STAUROSPORINE;

EID: 84455173162     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00736-11     Document Type: Article

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