메뉴 건너뛰기




Volumn 183, Issue 2, 2012, Pages 166-176

Discovery of factors linked to antimony resistance in Leishmania panamensis through differential proteome analysis

Author keywords

Antimony resistance; Leishmania panamensis; Proteomics; S Adenosylhomocysteine hydrolase; S Adenosylmethionine synthetase

Indexed keywords

ADENOSYLHOMOCYSTEINASE; ANTIMONY; METHIONINE ADENOSYLTRANSFERASE; PROTEOME; THIOL; TRYPANOTHIONE;

EID: 84859612403     PISSN: 01666851     EISSN: 18729428     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2012.03.002     Document Type: Article
Times cited : (74)

References (77)
  • 1
    • 0033517487 scopus 로고    scopus 로고
    • Leishmaniasis
    • B.L. Herwaldt Leishmaniasis Lancet 354 9185 1999 1191 1199
    • (1999) Lancet , vol.354 , Issue.9185 , pp. 1191-1199
    • Herwaldt, B.L.1
  • 2
    • 0030997216 scopus 로고    scopus 로고
    • In vitro and in vivo resistance of Leishmania infantum to meglumine antimoniate: A study of 37 strains collected from patients with visceral leishmaniasis
    • F. Faraut-Gambarelli, R. Piarroux, M. Deniau, B. Giusiano, P. Marty, and G. Michel In vitro and in vivo resistance of Leishmania infantum to meglumine antimoniate: a study of 37 strains collected from patients with visceral leishmaniasis Antimicrob Agents Chemother 41 4 1997 827 830
    • (1997) Antimicrob Agents Chemother , vol.41 , Issue.4 , pp. 827-830
    • Faraut-Gambarelli, F.1    Piarroux, R.2    Deniau, M.3    Giusiano, B.4    Marty, P.5    Michel, G.6
  • 3
    • 0034780949 scopus 로고    scopus 로고
    • Drug resistance in Indian visceral leishmaniasis
    • S. Sundar Drug resistance in Indian visceral leishmaniasis Trop Med Int Health 6 11 2001 849 854
    • (2001) Trop Med Int Health , vol.6 , Issue.11 , pp. 849-854
    • Sundar, S.1
  • 4
    • 0033540005 scopus 로고    scopus 로고
    • Miltefosine: An oral agent, for the treatment of Indian visceral leishmaniasis
    • T.K. Jha, S. Sundar, C.P. Thakur, P. Bachmann, J. Karbwang, and C. Fischer Miltefosine: an oral agent, for the treatment of Indian visceral leishmaniasis N Engl J Med 341 24 1999 1795 1800
    • (1999) N Engl J Med , vol.341 , Issue.24 , pp. 1795-1800
    • Jha, T.K.1    Sundar, S.2    Thakur, C.P.3    Bachmann, P.4    Karbwang, J.5    Fischer, C.6
  • 6
    • 0026541511 scopus 로고
    • Allopurinol in the treatment of American cutaneous leishmaniasis
    • S. Martinez, and J.J. Marr Allopurinol in the treatment of American cutaneous leishmaniasis N Engl J Med 326 11 1992 741 744
    • (1992) N Engl J Med , vol.326 , Issue.11 , pp. 741-744
    • Martinez, S.1    Marr, J.J.2
  • 7
    • 0031043418 scopus 로고    scopus 로고
    • Treatment of cutaneous leishmaniasis with allopurinol and stibogluconate
    • S. Martinez, M. Gonzalez, and M.E. Vernaza Treatment of cutaneous leishmaniasis with allopurinol and stibogluconate Clin Infect Dis 24 2 1997 165 169
    • (1997) Clin Infect Dis , vol.24 , Issue.2 , pp. 165-169
    • Martinez, S.1    Gonzalez, M.2    Vernaza, M.E.3
  • 8
    • 0031049914 scopus 로고    scopus 로고
    • Inefficacy of allopurinol as monotherapy for Colombian cutaneous leishmaniasis. A randomized: Controlled trial
    • I. Velez, S. Agudelo, E. Hendrickx, J. Puerta, M. Grogl, and F. Modabber Inefficacy of allopurinol as monotherapy for Colombian cutaneous leishmaniasis. A randomized: controlled trial Ann Intern Med 126 3 1997 232 236
    • (1997) Ann Intern Med , vol.126 , Issue.3 , pp. 232-236
    • Velez, I.1    Agudelo, S.2    Hendrickx, E.3    Puerta, J.4    Grogl, M.5    Modabber, F.6
  • 9
    • 33646350272 scopus 로고    scopus 로고
    • Resistance to antimony and treatment failure in human Leishmania (Viannia) infection
    • R. Rojas, L. Valderrama, M. Valderrama, M.X. Varona, M. Ouellette, and N.G. Saravia Resistance to antimony and treatment failure in human Leishmania (Viannia) infection J Infect Dis 193 10 2006 1375 1383
    • (2006) J Infect Dis , vol.193 , Issue.10 , pp. 1375-1383
    • Rojas, R.1    Valderrama, L.2    Valderrama, M.3    Varona, M.X.4    Ouellette, M.5    Saravia, N.G.6
  • 10
    • 0029031644 scopus 로고
    • In vitro antileishmanial properties of tri- and pentavalent antimonial preparations
    • W.L. Roberts, J.D. Berman, and P.M. Rainey In vitro antileishmanial properties of tri- and pentavalent antimonial preparations Antimicrob Agents Chemother 39 6 1995 1234 1239
    • (1995) Antimicrob Agents Chemother , vol.39 , Issue.6 , pp. 1234-1239
    • Roberts, W.L.1    Berman, J.D.2    Rainey, P.M.3
  • 11
    • 0031760626 scopus 로고    scopus 로고
    • Axenically grown amastigotes of Leishmania infantum used as an in vitro model to investigate the pentavalent antimony mode of action
    • D. Sereno, M. Cavaleyra, K. Zemzoumi, S. Maquaire, A. Ouaissi, and J.L. Lemesre Axenically grown amastigotes of Leishmania infantum used as an in vitro model to investigate the pentavalent antimony mode of action Antimicrob Agents Chemother 42 12 1998 3097 3102
    • (1998) Antimicrob Agents Chemother , vol.42 , Issue.12 , pp. 3097-3102
    • Sereno, D.1    Cavaleyra, M.2    Zemzoumi, K.3    Maquaire, S.4    Ouaissi, A.5    Lemesre, J.L.6
  • 12
    • 0035830909 scopus 로고    scopus 로고
    • Novel intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani
    • P. Shaked-Mishan, N. Ulrich, M. Ephros, and D. Zilberstein Novel intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani J Biol Chem 276 6 2001 3971 3976
    • (2001) J Biol Chem , vol.276 , Issue.6 , pp. 3971-3976
    • Shaked-Mishan, P.1    Ulrich, N.2    Ephros, M.3    Zilberstein, D.4
  • 13
    • 0032990769 scopus 로고    scopus 로고
    • Stage-specific activity of pentavalent antimony against Leishmania donovani axenic amastigotes
    • M. Ephros, A. Bitnun, P. Shaked, E. Waldman, and D. Zilberstein Stage-specific activity of pentavalent antimony against Leishmania donovani axenic amastigotes Antimicrob Agents Chemother 43 2 1999 278 282
    • (1999) Antimicrob Agents Chemother , vol.43 , Issue.2 , pp. 278-282
    • Ephros, M.1    Bitnun, A.2    Shaked, P.3    Waldman, E.4    Zilberstein, D.5
  • 14
    • 0037412052 scopus 로고    scopus 로고
    • Thiol-induced reduction of antimony(V) into antimony(III): A comparative study with trypanothione, cysteinyl-glycine, cysteine and glutathione
    • S. Ferreira Cdos, P.S. Martins, C. Demicheli, C. Brochu, M. Ouellette, and F. Frezard Thiol-induced reduction of antimony(V) into antimony(III): a comparative study with trypanothione, cysteinyl-glycine, cysteine and glutathione Biometals 16 3 2003 441 446
    • (2003) Biometals , vol.16 , Issue.3 , pp. 441-446
    • Ferreira Cdos, S.1    Martins, P.S.2    Demicheli, C.3    Brochu, C.4    Ouellette, M.5    Frezard, F.6
  • 15
    • 4444301522 scopus 로고    scopus 로고
    • Leishmania major LmACR2 is a pentavalent antimony reductase that confers sensitivity to the drug pentostam
    • Y. Zhou, N. Messier, M. Ouellette, B.P. Rosen, and R. Mukhopadhyay Leishmania major LmACR2 is a pentavalent antimony reductase that confers sensitivity to the drug pentostam J Biol Chem 279 36 2004 37445 37451
    • (2004) J Biol Chem , vol.279 , Issue.36 , pp. 37445-37451
    • Zhou, Y.1    Messier, N.2    Ouellette, M.3    Rosen, B.P.4    Mukhopadhyay, R.5
  • 16
    • 3242748862 scopus 로고    scopus 로고
    • Reduction of anti-leishmanial pentavalent antimonial drugs by a parasite-specific thiol-dependent reductase, TDR1
    • H. Denton, J.C. McGregor, and G.H. Coombs Reduction of anti-leishmanial pentavalent antimonial drugs by a parasite-specific thiol-dependent reductase, TDR1 Biochem J 381 Pt 2 2004 405 412
    • (2004) Biochem J , vol.381 , Issue.PART 2 , pp. 405-412
    • Denton, H.1    McGregor, J.C.2    Coombs, G.H.3
  • 17
    • 0141994732 scopus 로고    scopus 로고
    • Antimony uptake systems in the protozoan parasite Leishmania and accumulation differences in antimony-resistant parasites
    • C. Brochu, J. Wang, G. Roy, N. Messier, X.Y. Wang, and N.G. Saravia Antimony uptake systems in the protozoan parasite Leishmania and accumulation differences in antimony-resistant parasites Antimicrob Agents Chemother 47 10 2003 3073 3079
    • (2003) Antimicrob Agents Chemother , vol.47 , Issue.10 , pp. 3073-3079
    • Brochu, C.1    Wang, J.2    Roy, G.3    Messier, N.4    Wang, X.Y.5    Saravia, N.G.6
  • 18
    • 3843084085 scopus 로고    scopus 로고
    • Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin
    • B. Gourbal, N. Sonuc, H. Bhattacharjee, D. Legare, S. Sundar, and M. Ouellette Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin J Biol Chem 279 30 2004 31010 31017
    • (2004) J Biol Chem , vol.279 , Issue.30 , pp. 31010-31017
    • Gourbal, B.1    Sonuc, N.2    Bhattacharjee, H.3    Legare, D.4    Sundar, S.5    Ouellette, M.6
  • 19
    • 7944237421 scopus 로고    scopus 로고
    • Leishmaniasis: Drugs in the clinic, resistance and new developments
    • M. Ouellette, J. Drummelsmith, and B. Papadopoulou Leishmaniasis: drugs in the clinic, resistance and new developments Drug Resist Updat 7 4-5 2004 257 266
    • (2004) Drug Resist Updat , vol.7 , Issue.45 , pp. 257-266
    • Ouellette, M.1    Drummelsmith, J.2    Papadopoulou, B.3
  • 20
    • 0029841913 scopus 로고    scopus 로고
    • Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania
    • R. Mukhopadhyay, S. Dey, N. Xu, D. Gage, J. Lightbody, and M. Ouellette Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania Proc Natl Acad Sci USA 93 19 1996 10383 10387
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.19 , pp. 10383-10387
    • Mukhopadhyay, R.1    Dey, S.2    Xu, N.3    Gage, D.4    Lightbody, J.5    Ouellette, M.6
  • 21
    • 0028145546 scopus 로고
    • High level arsenite resistance in Leishmania tarentolae is mediated by an active extrusion system
    • S. Dey, B. Papadopoulou, A. Haimeur, G. Roy, K. Grondin, and D. Dou High level arsenite resistance in Leishmania tarentolae is mediated by an active extrusion system Mol Biochem Parasitol 67 1 1994 49 57
    • (1994) Mol Biochem Parasitol , vol.67 , Issue.1 , pp. 49-57
    • Dey, S.1    Papadopoulou, B.2    Haimeur, A.3    Roy, G.4    Grondin, K.5    Dou, D.6
  • 22
    • 0031282335 scopus 로고    scopus 로고
    • Efflux systems and increased trypanothione levels in arsenite-resistant Leishmania
    • D. Legare, B. Papadopoulou, G. Roy, R. Mukhopadhyay, A. Haimeur, and S. Dey Efflux systems and increased trypanothione levels in arsenite-resistant Leishmania Exp Parasitol 87 3 1997 275 282
    • (1997) Exp Parasitol , vol.87 , Issue.3 , pp. 275-282
    • Legare, D.1    Papadopoulou, B.2    Roy, G.3    Mukhopadhyay, R.4    Haimeur, A.5    Dey, S.6
  • 23
    • 0034732687 scopus 로고    scopus 로고
    • Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (SbIII) resistant Leishmania tarentolae
    • A. Haimeur, C. Brochu, P. Genest, B. Papadopoulou, and M. Ouellette Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (SbIII) resistant Leishmania tarentolae Mol Biochem Parasitol 108 1 2000 131 135
    • (2000) Mol Biochem Parasitol , vol.108 , Issue.1 , pp. 131-135
    • Haimeur, A.1    Brochu, C.2    Genest, P.3    Papadopoulou, B.4    Ouellette, M.5
  • 24
    • 0032744407 scopus 로고    scopus 로고
    • Elevated levels of polyamines and trypanothione resulting from overexpression of the ornithine decarboxylase gene in arsenite-resistant Leishmania
    • A. Haimeur, C. Guimond, S. Pilote, R. Mukhopadhyay, B.P. Rosen, and R. Poulin Elevated levels of polyamines and trypanothione resulting from overexpression of the ornithine decarboxylase gene in arsenite-resistant Leishmania Mol Microbiol 34 4 1999 726 735
    • (1999) Mol Microbiol , vol.34 , Issue.4 , pp. 726-735
    • Haimeur, A.1    Guimond, C.2    Pilote, S.3    Mukhopadhyay, R.4    Rosen, B.P.5    Poulin, R.6
  • 25
    • 0035854830 scopus 로고    scopus 로고
    • The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase
    • D. Legare, D. Richard, R. Mukhopadhyay, Y.D. Stierhof, B.P. Rosen, and A. Haimeur The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase J Biol Chem 276 28 2001 26301 26307
    • (2001) J Biol Chem , vol.276 , Issue.28 , pp. 26301-26307
    • Legare, D.1    Richard, D.2    Mukhopadhyay, R.3    Stierhof, Y.D.4    Rosen, B.P.5    Haimeur, A.6
  • 26
    • 0030924243 scopus 로고    scopus 로고
    • Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae
    • K. Grondin, A. Haimeur, R. Mukhopadhyay, B.P. Rosen, and M. Ouellette Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae EMBO J 16 11 1997 3057 3065
    • (1997) EMBO J , vol.16 , Issue.11 , pp. 3057-3065
    • Grondin, K.1    Haimeur, A.2    Mukhopadhyay, R.3    Rosen, B.P.4    Ouellette, M.5
  • 27
    • 0032323671 scopus 로고    scopus 로고
    • Amplification of ABC transporter gene pgpA and of other heavy metal resistance genes in Leishmania tarentolae and their study by gene transfection and gene disruption
    • M. Ouellette, A. Haimeur, K. Grondin, D. Legare, and B. Papadopoulou Amplification of ABC transporter gene pgpA and of other heavy metal resistance genes in Leishmania tarentolae and their study by gene transfection and gene disruption Methods Enzymol 292 1998 182 193
    • (1998) Methods Enzymol , vol.292 , pp. 182-193
    • Ouellette, M.1    Haimeur, A.2    Grondin, K.3    Legare, D.4    Papadopoulou, B.5
  • 28
    • 10744222969 scopus 로고    scopus 로고
    • Modulation of gene expression in Leishmania drug resistant mutants as determined by targeted DNA microarrays
    • C. Guimond, N. Trudel, C. Brochu, N. Marquis, A. El Fadili, and R. Peytavi Modulation of gene expression in Leishmania drug resistant mutants as determined by targeted DNA microarrays Nucleic Acids Res 31 20 2003 5886 5896
    • (2003) Nucleic Acids Res , vol.31 , Issue.20 , pp. 5886-5896
    • Guimond, C.1    Trudel, N.2    Brochu, C.3    Marquis, N.4    El Fadili, A.5    Peytavi, R.6
  • 29
    • 4444278762 scopus 로고    scopus 로고
    • A trypanothione-dependent glyoxalase i with a prokaryotic ancestry in Leishmania major
    • T.J. Vickers, N. Greig, and A.H. Fairlamb A trypanothione-dependent glyoxalase I with a prokaryotic ancestry in Leishmania major Proc Natl Acad Sci USA 101 36 2004 13186 13191
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.36 , pp. 13186-13191
    • Vickers, T.J.1    Greig, N.2    Fairlamb, A.H.3
  • 30
    • 10444255569 scopus 로고    scopus 로고
    • Leishmania major elongation factor 1B complex has trypanothione S-transferase and peroxidase activity
    • T.J. Vickers, S. Wyllie, and A.H. Fairlamb Leishmania major elongation factor 1B complex has trypanothione S-transferase and peroxidase activity J Biol Chem 279 47 2004 49003 49009
    • (2004) J Biol Chem , vol.279 , Issue.47 , pp. 49003-49009
    • Vickers, T.J.1    Wyllie, S.2    Fairlamb, A.H.3
  • 32
    • 0031861799 scopus 로고    scopus 로고
    • Gene amplification in Leishmania tarentolae selected for resistance to sodium stibogluconate
    • A. Haimeur, and M. Ouellette Gene amplification in Leishmania tarentolae selected for resistance to sodium stibogluconate Antimicrob Agents Chemother 42 7 1998 1689 1694
    • (1998) Antimicrob Agents Chemother , vol.42 , Issue.7 , pp. 1689-1694
    • Haimeur, A.1    Ouellette, M.2
  • 33
    • 0037871961 scopus 로고    scopus 로고
    • Structural and functional analysis of an amplification containing a PGPA gene in a glucantime-resistant Leishmania (Viannia) guyanensis cell line
    • C. Anacleto, M.C. Abdo, A.V. Ferreira, S.M. Murta, A.J. Romanha, and A.P. Fernandes Structural and functional analysis of an amplification containing a PGPA gene in a glucantime-resistant Leishmania (Viannia) guyanensis cell line Parasitol Res 90 2 2003 110 118
    • (2003) Parasitol Res , vol.90 , Issue.2 , pp. 110-118
    • Anacleto, C.1    Abdo, M.C.2    Ferreira, A.V.3    Murta, S.M.4    Romanha, A.J.5    Fernandes, A.P.6
  • 34
    • 68049132858 scopus 로고    scopus 로고
    • Down regulation of KMP-11 in Leishmania infantum axenic antimony resistant amastigotes as revealed by a proteomic screen
    • K. El Fadili, J. Drummelsmith, G. Roy, A. Jardim, and M. Ouellette Down regulation of KMP-11 in Leishmania infantum axenic antimony resistant amastigotes as revealed by a proteomic screen Exp Parasitol 123 1 2009 51 57
    • (2009) Exp Parasitol , vol.123 , Issue.1 , pp. 51-57
    • El Fadili, K.1    Drummelsmith, J.2    Roy, G.3    Jardim, A.4    Ouellette, M.5
  • 35
    • 0033747235 scopus 로고    scopus 로고
    • Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models
    • G. Roy, C. Dumas, D. Sereno, Y. Wu, A.K. Singh, and M.J. Tremblay Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models Mol Biochem Parasitol 110 2 2000 195 206
    • (2000) Mol Biochem Parasitol , vol.110 , Issue.2 , pp. 195-206
    • Roy, G.1    Dumas, C.2    Sereno, D.3    Wu, Y.4    Singh, A.K.5    Tremblay, M.J.6
  • 36
    • 29144474202 scopus 로고    scopus 로고
    • Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro
    • I.C. Romero, N.G. Saravia, and J. Walker Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro J Parasitol 91 6 2005 1474 1479
    • (2005) J Parasitol , vol.91 , Issue.6 , pp. 1474-1479
    • Romero, I.C.1    Saravia, N.G.2    Walker, J.3
  • 37
    • 0032445395 scopus 로고    scopus 로고
    • Permissiveness of human monocytes and monocyte-derived macrophages to infection by promastigotes of Leishmania (Viannia) panamensis
    • F. Bosque, G. Milon, L. Valderrama, and N.G. Saravia Permissiveness of human monocytes and monocyte-derived macrophages to infection by promastigotes of Leishmania (Viannia) panamensis J Parasitol 84 6 1998 1250 1256
    • (1998) J Parasitol , vol.84 , Issue.6 , pp. 1250-1256
    • Bosque, F.1    Milon, G.2    Valderrama, L.3    Saravia, N.G.4
  • 38
    • 0029128640 scopus 로고
    • Drug cytotoxicity assay for African trypanosomes and Leishmania species
    • A.L. Bodley, M.W. McGarry, and T.A. Shapiro Drug cytotoxicity assay for African trypanosomes and Leishmania species J Infect Dis 172 4 1995 1157 1159
    • (1995) J Infect Dis , vol.172 , Issue.4 , pp. 1157-1159
    • Bodley, A.L.1    McGarry, M.W.2    Shapiro, T.A.3
  • 39
    • 0035997275 scopus 로고    scopus 로고
    • Establishing two-dimensional gels for the analysis of Leishmania proteomes
    • N. Acestor, S. Masina, J. Walker, N.G. Saravia, N. Fasel, and M. Quadroni Establishing two-dimensional gels for the analysis of Leishmania proteomes Proteomics 2 7 2002 877 879
    • (2002) Proteomics , vol.2 , Issue.7 , pp. 877-879
    • Acestor, N.1    Masina, S.2    Walker, J.3    Saravia, N.G.4    Fasel, N.5    Quadroni, M.6
  • 40
    • 0142030010 scopus 로고    scopus 로고
    • Mapping the proteome of Leishmania Viannia parasites using two-dimensional polyacrylamide gel electrophoresis and associated technologies
    • R. Gongora, N. Acestor, M. Quadroni, N. Fasel, N.G. Saravia, and J. Walker Mapping the proteome of Leishmania Viannia parasites using two-dimensional polyacrylamide gel electrophoresis and associated technologies Biomedica 23 2 2003 153 160
    • (2003) Biomedica , vol.23 , Issue.2 , pp. 153-160
    • Gongora, R.1    Acestor, N.2    Quadroni, M.3    Fasel, N.4    Saravia, N.G.5    Walker, J.6
  • 41
    • 0019887744 scopus 로고
    • Phase separation of integral membrane proteins in Triton X-114 solution
    • C. Bordier Phase separation of integral membrane proteins in Triton X-114 solution J Biol Chem 256 4 1981 1604 1607
    • (1981) J Biol Chem , vol.256 , Issue.4 , pp. 1604-1607
    • Bordier, C.1
  • 42
    • 0018084288 scopus 로고
    • Analytical techniques for cell fractions. XXI. Two-dimensional analysis of serum and tissue proteins: Multiple isoelectric focusing
    • N.G. Anderson, and N.L. Anderson Analytical techniques for cell fractions. XXI. Two-dimensional analysis of serum and tissue proteins: multiple isoelectric focusing Anal Biochem 85 2 1978 331 340
    • (1978) Anal Biochem , vol.85 , Issue.2 , pp. 331-340
    • Anderson, N.G.1    Anderson, N.L.2
  • 43
    • 0018348952 scopus 로고
    • Analytical techniques for cell fractions. XXIV. Isoelectric point standards for two-dimensional electrophoresis
    • N.L. Anderson, and B.J. Hickman Analytical techniques for cell fractions. XXIV. Isoelectric point standards for two-dimensional electrophoresis Anal Biochem 93 2 1979 312 320
    • (1979) Anal Biochem , vol.93 , Issue.2 , pp. 312-320
    • Anderson, N.L.1    Hickman, B.J.2
  • 44
    • 0025733509 scopus 로고
    • Quantitation of human leukocyte proteins after silver staining: A study with two-dimensional electrophoresis
    • C.S. Giometti, M.A. Gemmell, S.L. Tollaksen, and J. Taylor Quantitation of human leukocyte proteins after silver staining: a study with two-dimensional electrophoresis Electrophoresis 12 7-8 1991 536 543
    • (1991) Electrophoresis , vol.12 , Issue.78 , pp. 536-543
    • Giometti, C.S.1    Gemmell, M.A.2    Tollaksen, S.L.3    Taylor, J.4
  • 45
    • 0035403371 scopus 로고    scopus 로고
    • A new silver staining apparatus and procedure for matrix-assisted laser desorption/ionization-time of flight analysis of proteins after two-dimensional electrophoresis
    • P. Sinha, J. Poland, M. Schnolzer, and T. Rabilloud A new silver staining apparatus and procedure for matrix-assisted laser desorption/ionization-time of flight analysis of proteins after two-dimensional electrophoresis Proteomics 1 7 2001 835 840
    • (2001) Proteomics , vol.1 , Issue.7 , pp. 835-840
    • Sinha, P.1    Poland, J.2    Schnolzer, M.3    Rabilloud, T.4
  • 46
    • 0031444888 scopus 로고    scopus 로고
    • Melanie II - A third-generation software package for analysis of two-dimensional electrophoresis images: I. Features and user interface
    • R.D. Appel, P.M. Palagi, D. Walther, J.R. Vargas, J.C. Sanchez, and F. Ravier Melanie II - a third-generation software package for analysis of two-dimensional electrophoresis images: I. Features and user interface Electrophoresis 18 15 1997 2724 2734
    • (1997) Electrophoresis , vol.18 , Issue.15 , pp. 2724-2734
    • Appel, R.D.1    Palagi, P.M.2    Walther, D.3    Vargas, J.R.4    Sanchez, J.C.5    Ravier, F.6
  • 47
    • 0141909066 scopus 로고    scopus 로고
    • Proteome mapping of the protozoan parasite Leishmania and application to the study of drug targets and resistance mechanisms
    • J. Drummelsmith, V. Brochu, I. Girard, N. Messier, and M. Ouellette Proteome mapping of the protozoan parasite Leishmania and application to the study of drug targets and resistance mechanisms Mol Cell Proteomics 2 3 2003 146 155
    • (2003) Mol Cell Proteomics , vol.2 , Issue.3 , pp. 146-155
    • Drummelsmith, J.1    Brochu, V.2    Girard, I.3    Messier, N.4    Ouellette, M.5
  • 48
    • 0000857494 scopus 로고
    • An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database
    • J.K. Eng, A.L. McCormack, and J.R. Yates An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database J Am Soc Mass Spectrom 5 11 1994 976 989
    • (1994) J Am Soc Mass Spectrom , vol.5 , Issue.11 , pp. 976-989
    • Eng, J.K.1    McCormack, A.L.2    Yates, J.R.3
  • 49
    • 69949093708 scopus 로고    scopus 로고
    • Development of a multilocus microsatellite typing approach for discriminating strains of Leishmania (Viannia) species
    • R. Oddone, C. Schweynoch, G. Schonian, S. de Sousa Cdos, E. Cupolillo, and D. Espinosa Development of a multilocus microsatellite typing approach for discriminating strains of Leishmania (Viannia) species J Clin Microbiol 47 9 2009 2818 2825
    • (2009) J Clin Microbiol , vol.47 , Issue.9 , pp. 2818-2825
    • Oddone, R.1    Schweynoch, C.2    Schonian, G.3    De Sousa Cdos, S.4    Cupolillo, E.5    Espinosa, D.6
  • 50
    • 0036668518 scopus 로고    scopus 로고
    • A proteomic approach to identify developmentally regulated proteins in Leishmania infantum
    • Y. El Fakhry, M. Ouellette, and B. Papadopoulou A proteomic approach to identify developmentally regulated proteins in Leishmania infantum Proteomics 2 8 2002 1007 1017
    • (2002) Proteomics , vol.2 , Issue.8 , pp. 1007-1017
    • El Fakhry, Y.1    Ouellette, M.2    Papadopoulou, B.3
  • 51
    • 30544434167 scopus 로고    scopus 로고
    • Comparative protein profiling identifies elongation factor-1beta and tryparedoxin peroxidase as factors associated with metastasis in Leishmania guyanensis
    • J. Walker, N. Acestor, R. Gongora, M. Quadroni, I. Segura, and N. Fasel Comparative protein profiling identifies elongation factor-1beta and tryparedoxin peroxidase as factors associated with metastasis in Leishmania guyanensis Mol Biochem Parasitol 145 2 2006 254 264
    • (2006) Mol Biochem Parasitol , vol.145 , Issue.2 , pp. 254-264
    • Walker, J.1    Acestor, N.2    Gongora, R.3    Quadroni, M.4    Segura, I.5    Fasel, N.6
  • 52
    • 4043094169 scopus 로고    scopus 로고
    • Differential protein expression analysis of Leishmania major reveals novel roles for methionine adenosyltransferase and S-adenosylmethionine in methotrexate resistance
    • J. Drummelsmith, I. Girard, N. Trudel, and M. Ouellette Differential protein expression analysis of Leishmania major reveals novel roles for methionine adenosyltransferase and S-adenosylmethionine in methotrexate resistance J Biol Chem 279 32 2004 33273 33280
    • (2004) J Biol Chem , vol.279 , Issue.32 , pp. 33273-33280
    • Drummelsmith, J.1    Girard, I.2    Trudel, N.3    Ouellette, M.4
  • 53
    • 0141520538 scopus 로고    scopus 로고
    • Developmentally induced changes of the proteome in the protozoan parasite Leishmania donovani
    • M. Bente, S. Harder, M. Wiesgigl, J. Heukeshoven, C. Gelhaus, and E. Krause Developmentally induced changes of the proteome in the protozoan parasite Leishmania donovani Proteomics 3 9 2003 1811 1829
    • (2003) Proteomics , vol.3 , Issue.9 , pp. 1811-1829
    • Bente, M.1    Harder, S.2    Wiesgigl, M.3    Heukeshoven, J.4    Gelhaus, C.5    Krause, E.6
  • 54
    • 33645847251 scopus 로고    scopus 로고
    • Identification of developmentally-regulated proteins in Leishmania panamensis by proteome profiling of promastigotes and axenic amastigotes
    • J. Walker, J.J. Vasquez, M.A. Gomez, J. Drummelsmith, R. Burchmore, and I. Girard Identification of developmentally-regulated proteins in Leishmania panamensis by proteome profiling of promastigotes and axenic amastigotes Mol Biochem Parasitol 147 1 2006 64 73
    • (2006) Mol Biochem Parasitol , vol.147 , Issue.1 , pp. 64-73
    • Walker, J.1    Vasquez, J.J.2    Gomez, M.A.3    Drummelsmith, J.4    Burchmore, R.5    Girard, I.6
  • 55
    • 33645999355 scopus 로고    scopus 로고
    • S-adenosylmethionine: Jack of all trades and master of everything?
    • W.A. Loenen S-adenosylmethionine: jack of all trades and master of everything? Biochem Soc Trans 34 Pt 2 2006 330 333
    • (2006) Biochem Soc Trans , vol.34 , Issue.PART 2 , pp. 330-333
    • Loenen, W.A.1
  • 56
    • 27644513649 scopus 로고    scopus 로고
    • Gene expression analysis of the mechanism of natural Sb(V) resistance in Leishmania donovani isolates from Nepal
    • S. Decuypere, S. Rijal, V. Yardley, S. De Doncker, T. Laurent, and B. Khanal Gene expression analysis of the mechanism of natural Sb(V) resistance in Leishmania donovani isolates from Nepal Antimicrob Agents Chemother 49 11 2005 4616 4621
    • (2005) Antimicrob Agents Chemother , vol.49 , Issue.11 , pp. 4616-4621
    • Decuypere, S.1    Rijal, S.2    Yardley, V.3    De Doncker, S.4    Laurent, T.5    Khanal, B.6
  • 57
    • 29944447375 scopus 로고    scopus 로고
    • Resistance of Leishmania donovani to sodium stibogluconate is related to the expression of host and parasite gamma-glutamylcysteine synthetase
    • K.C. Carter, S. Hutchison, F.L. Henriquez, D. Legare, M. Ouellette, and C.W. Roberts Resistance of Leishmania donovani to sodium stibogluconate is related to the expression of host and parasite gamma-glutamylcysteine synthetase Antimicrob Agents Chemother 50 1 2006 88 95
    • (2006) Antimicrob Agents Chemother , vol.50 , Issue.1 , pp. 88-95
    • Carter, K.C.1    Hutchison, S.2    Henriquez, F.L.3    Legare, D.4    Ouellette, M.5    Roberts, C.W.6
  • 58
    • 77954761899 scopus 로고    scopus 로고
    • Elevated levels of tryparedoxin peroxidase in antimony unresponsive Leishmania donovani field isolates
    • S. Wyllie, G. Mandal, N. Singh, S. Sundar, A.H. Fairlamb, and M. Chatterjee Elevated levels of tryparedoxin peroxidase in antimony unresponsive Leishmania donovani field isolates Mol Biochem Parasitol 173 2 2010 162 164
    • (2010) Mol Biochem Parasitol , vol.173 , Issue.2 , pp. 162-164
    • Wyllie, S.1    Mandal, G.2    Singh, N.3    Sundar, S.4    Fairlamb, A.H.5    Chatterjee, M.6
  • 59
    • 77950336943 scopus 로고    scopus 로고
    • Assessing aquaglyceroporin gene status and expression profile in antimony-susceptible and -resistant clinical isolates of Leishmania donovani from India
    • S. Mandal, M. Maharjan, S. Singh, M. Chatterjee, and R. Madhubala Assessing aquaglyceroporin gene status and expression profile in antimony-susceptible and -resistant clinical isolates of Leishmania donovani from India J Antimicrob Chemother 65 3 2010 496 507
    • (2010) J Antimicrob Chemother , vol.65 , Issue.3 , pp. 496-507
    • Mandal, S.1    Maharjan, M.2    Singh, S.3    Chatterjee, M.4    Madhubala, R.5
  • 60
    • 57049136229 scopus 로고    scopus 로고
    • Antimony resistance and trypanothione in experimentally selected and clinical strains of Leishmania panamensis
    • D.A. Goyeneche-Patino, L. Valderrama, J. Walker, and N.G. Saravia Antimony resistance and trypanothione in experimentally selected and clinical strains of Leishmania panamensis Antimicrob Agents Chemother 52 12 2008 4503 4506
    • (2008) Antimicrob Agents Chemother , vol.52 , Issue.12 , pp. 4503-4506
    • Goyeneche-Patino, D.A.1    Valderrama, L.2    Walker, J.3    Saravia, N.G.4
  • 61
    • 79952986204 scopus 로고    scopus 로고
    • Comparison of gene expression patterns among Leishmania braziliensis clinical isolates showing a different in vitro susceptibility to pentavalent antimony
    • V. Adaui, K. Schnorbusch, M. Zimic, A. Gutierrez, S. Decuypere, and M. Vanaerschot Comparison of gene expression patterns among Leishmania braziliensis clinical isolates showing a different in vitro susceptibility to pentavalent antimony Parasitology 138 2 2011 183 193
    • (2011) Parasitology , vol.138 , Issue.2 , pp. 183-193
    • Adaui, V.1    Schnorbusch, K.2    Zimic, M.3    Gutierrez, A.4    Decuypere, S.5    Vanaerschot, M.6
  • 62
    • 77954028485 scopus 로고    scopus 로고
    • Targeted gene expression profiling in Leishmania braziliensis and Leishmania guyanensis parasites isolated from Brazilian patients with different antimonial treatment outcomes
    • D.C. Torres, V. Adaui, M. Ribeiro-Alves, G.A. Romero, J. Arevalo, and E. Cupolillo Targeted gene expression profiling in Leishmania braziliensis and Leishmania guyanensis parasites isolated from Brazilian patients with different antimonial treatment outcomes Infect Genet Evol 10 6 2010 727 733
    • (2010) Infect Genet Evol , vol.10 , Issue.6 , pp. 727-733
    • Torres, D.C.1    Adaui, V.2    Ribeiro-Alves, M.3    Romero, G.A.4    Arevalo, J.5    Cupolillo, E.6
  • 63
    • 77957879848 scopus 로고    scopus 로고
    • Linking in vitro and in vivo survival of clinical Leishmania donovani strains
    • M. Vanaerschot, I. Maes, M. Ouakad, V. Adaui, L. Maes, and S. De Doncker Linking in vitro and in vivo survival of clinical Leishmania donovani strains PLoS One 5 8 2010 e12211
    • (2010) PLoS One , vol.5 , Issue.8 , pp. 12211
    • Vanaerschot, M.1    Maes, I.2    Ouakad, M.3    Adaui, V.4    Maes, L.5    De Doncker, S.6
  • 64
    • 0344352478 scopus 로고    scopus 로고
    • Oligopeptidase B-dependent signaling mediates host cell invasion by Trypanosoma cruzi
    • E.V. Caler, S. Vaena de Avalos, P.A. Haynes, N.W. Andrews, and B.A. Burleigh Oligopeptidase B-dependent signaling mediates host cell invasion by Trypanosoma cruzi EMBO J 17 17 1998 4975 4986
    • (1998) EMBO J , vol.17 , Issue.17 , pp. 4975-4986
    • Caler, E.V.1    Vaena De Avalos, S.2    Haynes, P.A.3    Andrews, N.W.4    Burleigh, B.A.5
  • 65
    • 0033543644 scopus 로고    scopus 로고
    • Oligopeptidase B from Trypanosoma brucei: A new member of an emerging subgroup of serine oligopeptidases
    • R.E. Morty, J.D. Lonsdale-Eccles, J. Morehead, E.V. Caler, R. Mentele, and E.A. Auerswald Oligopeptidase B from Trypanosoma brucei: a new member of an emerging subgroup of serine oligopeptidases J Biol Chem 274 37 1999 26149 26156
    • (1999) J Biol Chem , vol.274 , Issue.37 , pp. 26149-26156
    • Morty, R.E.1    Lonsdale-Eccles, J.D.2    Morehead, J.3    Caler, E.V.4    Mentele, R.5    Auerswald, E.A.6
  • 67
    • 29044439557 scopus 로고    scopus 로고
    • Characterization of a methionine adenosyltransferase over-expressing strain in the trypanosomatid Leishmania donovani
    • Y. Perez-Pertejo, R.M. Reguera, D. Ordonez, and R. Balana-Fouce Characterization of a methionine adenosyltransferase over-expressing strain in the trypanosomatid Leishmania donovani Biochim Biophys Acta 1760 1 2006 10 19
    • (2006) Biochim Biophys Acta , vol.1760 , Issue.1 , pp. 10-19
    • Perez-Pertejo, Y.1    Reguera, R.M.2    Ordonez, D.3    Balana-Fouce, R.4
  • 68
    • 67649397588 scopus 로고    scopus 로고
    • Epigenetic regulation in African trypanosomes: A new kid on the block
    • L.M. Figueiredo, G.A. Cross, and C.J. Janzen Epigenetic regulation in African trypanosomes: a new kid on the block Nat Rev Microbiol 7 7 2009 504 513
    • (2009) Nat Rev Microbiol , vol.7 , Issue.7 , pp. 504-513
    • Figueiredo, L.M.1    Cross, G.A.2    Janzen, C.J.3
  • 70
    • 7644219918 scopus 로고    scopus 로고
    • The heat shock protein HSP70 and heat shock cognate protein HSC70 contribute to antimony tolerance in the protozoan parasite leishmania
    • C. Brochu, A. Haimeur, and M. Ouellette The heat shock protein HSP70 and heat shock cognate protein HSC70 contribute to antimony tolerance in the protozoan parasite leishmania Cell Stress Chaperones 9 3 2004 294 303
    • (2004) Cell Stress Chaperones , vol.9 , Issue.3 , pp. 294-303
    • Brochu, C.1    Haimeur, A.2    Ouellette, M.3
  • 71
    • 0031036746 scopus 로고    scopus 로고
    • Stress-inducible: Murine protein mSTI1. Characterization of binding domains for heat shock proteins and in vitro phosphorylation by different kinases
    • M. Lassle, G.L. Blatch, V. Kundra, T. Takatori, and B.R. Zetter Stress-inducible: murine protein mSTI1. Characterization of binding domains for heat shock proteins and in vitro phosphorylation by different kinases J Biol Chem 272 3 1997 1876 1884
    • (1997) J Biol Chem , vol.272 , Issue.3 , pp. 1876-1884
    • Lassle, M.1    Blatch, G.L.2    Kundra, V.3    Takatori, T.4    Zetter, B.R.5
  • 72
    • 0035930633 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae multidrug resistance gene expression inversely correlates with the status of the F(0) component of the mitochondrial ATPase
    • X. Zhang, and W.S. Moye-Rowley Saccharomyces cerevisiae multidrug resistance gene expression inversely correlates with the status of the F(0) component of the mitochondrial ATPase J Biol Chem 276 51 2001 47844 47852
    • (2001) J Biol Chem , vol.276 , Issue.51 , pp. 47844-47852
    • Zhang, X.1    Moye-Rowley, W.S.2
  • 73
    • 0035257013 scopus 로고    scopus 로고
    • Rab proteins as membrane organizers
    • M. Zerial, and H. McBride Rab proteins as membrane organizers Nat Rev Mol Cell Biol 2 2 2001 107 117
    • (2001) Nat Rev Mol Cell Biol , vol.2 , Issue.2 , pp. 107-117
    • Zerial, M.1    McBride, H.2
  • 74
    • 0141920730 scopus 로고    scopus 로고
    • Rab7 prevents growth factor-independent survival by inhibiting cell-autonomous nutrient transporter expression
    • A.L. Edinger, R.M. Cinalli, and C.B. Thompson Rab7 prevents growth factor-independent survival by inhibiting cell-autonomous nutrient transporter expression Dev Cell 5 4 2003 571 582
    • (2003) Dev Cell , vol.5 , Issue.4 , pp. 571-582
    • Edinger, A.L.1    Cinalli, R.M.2    Thompson, C.B.3
  • 75
    • 0030833312 scopus 로고    scopus 로고
    • Experimentally induced changes in the endocytic traffic of P-glycoprotein alter drug resistance of cancer cells
    • H. Kim, M. Barroso, R. Samanta, L. Greenberger, and E. Sztul Experimentally induced changes in the endocytic traffic of P-glycoprotein alter drug resistance of cancer cells Am J Physiol 273 2 Pt 1 1997 C687 C702
    • (1997) Am J Physiol , vol.273 , Issue.2 PART 1
    • Kim, H.1    Barroso, M.2    Samanta, R.3    Greenberger, L.4    Sztul, E.5
  • 76
    • 80051783081 scopus 로고    scopus 로고
    • Differential expression of proteins in antimony-susceptible and -resistant isolates of Leishmania donovani
    • [Jun 25 Epub]
    • N. Biyani, A.K. Singh, S. Mandal, B. Chawla, and R. Madhubala Differential expression of proteins in antimony-susceptible and -resistant isolates of Leishmania donovani Mol Biochem Parasitol 2011 [Jun 25 Epub]
    • (2011) Mol Biochem Parasitol
    • Biyani, N.1    Singh, A.K.2    Mandal, S.3    Chawla, B.4    Madhubala, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.