Mutagenesis studies of the 14 Å internal cavity of histone deacetylase 1: Insights toward the acetate-escape hypothesis and selective inhibitor design

Journal of Medicinal Chemistry

Volumn 57, Issue 3, 2014, Pages 642-650

  Wambua, Magdalene K ^a   Nalawansha, Dhanusha A ^a   Negmeldin, Ahmed T ^a   Pflum, Mary Kay H ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETATES; AMINO ACIDS; ANTINEOPLASTIC AGENTS; CATALYTIC DOMAIN; DEPSIPEPTIDES; DRUG DESIGN; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; JURKAT CELLS; MOLECULAR DOCKING SIMULATION; MUTATION;

EID: 84894031215     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401837e     Document Type: Article

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