Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 11, 2007, Pages 4297-4302

  Guo, Liang ^a   Han, Aidong ^a,b   Bates, Darren L ^a   Cao, Jue ^a   Chen, Lin ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Amyloid; Transcription

Indexed keywords

AMYLOID; GLUTAMINE; HISTONE DEACETYLASE 4; HDAC4 PROTEIN, HUMAN; HISTONE DEACETYLASE; REPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METHODOLOGY; MOLECULAR GENETICS; MUTAGENESIS; PH; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; GLUTAMINE; HISTONE DEACETYLASES; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 34248344283     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0608041104     Document Type: Article

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