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Volumn 69, Issue , 2014, Pages 145-156

Novel molecular approaches for improving enzymatic and nonenzymatic detoxification of 4-hydroxynonenal: Toward the discovery of a novel class of bioactive compounds

Author keywords

4 Hydroxy trans 2 nonenal; Advanced lipoxidation end products; Carnosine; Free radicals; Sequestering agents

Indexed keywords

4-HYDROXY-TRANS-2-NONENAL; ADVANCED LIPOXIDATION END PRODUCTS; CARNOSINE; FREE RADICALS; SEQUESTERING AGENTS;

EID: 84893822259     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.01.017     Document Type: Review
Times cited : (41)

References (106)
  • 1
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • H. Esterbauer, R.J. Schaur, and H. Zollner Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes Free Radic. Biol. Med. 11 1991 81 128 (Pubitemid 121003917)
    • (1991) Free Radical Biology and Medicine , vol.11 , Issue.1 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 2
    • 70349492687 scopus 로고    scopus 로고
    • Molecular mechanisms of 4-hydroxy-2-nonenal and acrolein toxicity: Nucleophilic targets and adduct formation
    • R.M. LoPachin, T. Gavin, D.R. Petersen, and D.S. Barber Molecular mechanisms of 4-hydroxy-2-nonenal and acrolein toxicity: nucleophilic targets and adduct formation Chem. Res. Toxicol. 22 2009 1499 1508
    • (2009) Chem. Res. Toxicol. , vol.22 , pp. 1499-1508
    • Lopachin, R.M.1    Gavin, T.2    Petersen, D.R.3    Barber, D.S.4
  • 3
    • 0043172509 scopus 로고    scopus 로고
    • Basic aspects of the biochemical reactivity of 4-hydroxynonenal
    • DOI 10.1016/S0098-2997(03)00009-8
    • R.J. Schaur Basic aspects of the biochemical reactivity of 4-hydroxynonenal Mol. Aspects Med. 24 2003 149 159 (Pubitemid 36945015)
    • (2003) Molecular Aspects of Medicine , vol.24 , Issue.4-5 , pp. 149-159
    • Schaur, R.J.1
  • 4
    • 0036852609 scopus 로고    scopus 로고
    • Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal
    • DOI 10.1021/tx025590o
    • J.A. Doorn, and D.R. Petersen Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal Chem. Res. Toxicol. 15 2002 1445 1450 (Pubitemid 35364906)
    • (2002) Chemical Research in Toxicology , vol.15 , Issue.11 , pp. 1445-1450
    • Doorn, J.A.1    Petersen, D.R.2
  • 5
    • 58149163597 scopus 로고    scopus 로고
    • Synaptosomal toxicity and nucleophilic targets of 4-hydroxy-2-nonenal
    • R.M. Lopachin, B.C. Geohagen, and T. Gavin Synaptosomal toxicity and nucleophilic targets of 4-hydroxy-2-nonenal Toxicol. Sci. 107 2009 171 181
    • (2009) Toxicol. Sci. , vol.107 , pp. 171-181
    • Lopachin, R.M.1    Geohagen, B.C.2    Gavin, T.3
  • 6
    • 52049088770 scopus 로고    scopus 로고
    • Oxidative stress and covalent modification of protein with bioactive aldehydes
    • P.A. Grimsrud, H. Xie, T.J. Griffin, and D.A. Bernlohr Oxidative stress and covalent modification of protein with bioactive aldehydes J. Biol. Chem. 283 2008 21837 21841
    • (2008) J. Biol. Chem. , vol.283 , pp. 21837-21841
    • Grimsrud, P.A.1    Xie, H.2    Griffin, T.J.3    Bernlohr, D.A.4
  • 7
    • 79954521978 scopus 로고    scopus 로고
    • Michael-type addition of azoles of broad-scale acidity to methyl acrylate
    • S. Boncel, K. Saletra, B. Hefczyc, and K. Walczak Michael-type addition of azoles of broad-scale acidity to methyl acrylate Beilstein J. Org. Chem. 7 2011 173 178
    • (2011) Beilstein J. Org. Chem. , vol.7 , pp. 173-178
    • Boncel, S.1    Saletra, K.2    Hefczyc, B.3    Walczak, K.4
  • 8
    • 3242768438 scopus 로고    scopus 로고
    • Modification of cytochrome c by 4-hydroxy-2-nonenal: Evidence for histidine, lysine, and arginine-aldehyde adducts
    • DOI 10.1016/j.jasms.2004.03.013, PII S1044030504001898
    • A.L. Isom, S. Barnes, L. Wilson, M. Kirk, L. Coward, and V. Darley-Usmar Modification of cytochrome c by 4-hydroxy-2-nonenal: evidence for histidine, lysine, and arginine-aldehyde adducts J. Am. Soc. Mass Spectrom. 15 2004 1136 1147 (Pubitemid 38970057)
    • (2004) Journal of the American Society for Mass Spectrometry , vol.15 , Issue.8 , pp. 1136-1147
    • Isom, A.L.1    Barnes, S.2    Wilson, L.3    Kirk, M.4    Coward, L.5    Darley-Usmar, V.6
  • 9
    • 84866724337 scopus 로고    scopus 로고
    • Mass spectrometric evidence of malonaldehyde and 4-hydroxynonenal adductions to radical-scavenging soy peptides
    • J. Zhao, J. Chen, H. Zhu, and Y.L. Xiong Mass spectrometric evidence of malonaldehyde and 4-hydroxynonenal adductions to radical-scavenging soy peptides J. Agric. Food Chem. 60 2012 9727 9736
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 9727-9736
    • Zhao, J.1    Chen, J.2    Zhu, H.3    Xiong, Y.L.4
  • 10
    • 33846849624 scopus 로고    scopus 로고
    • Submicromolar concentrations of 4-hydroxynonenal induce glutamate cysteine ligase expression in HBE1 cells
    • DOI 10.1179/135100007X162266
    • H. Zhang, N. Court, and H.J. Forman Submicromolar concentrations of 4-hydroxynonenal induce glutamate cysteine ligase expression in HBE1 cells Redox Rep. 12 2007 101 106 (Pubitemid 46210366)
    • (2007) Redox Report , vol.12 , Issue.1-2 , pp. 101-106
    • Zhang, H.1    Court, N.2    Forman, H.J.3
  • 12
    • 78049269927 scopus 로고    scopus 로고
    • Low concentration of 4-hydroxy hexenal increases heme oxygenase-1 expression through activation of Nrf2 and antioxidative activity in vascular endothelial cells
    • A. Ishikado, Y. Nishio, K. Morino, S. Ugi, H. Kondo, T. Makino, A. Kashiwagi, and H. Maegawa Low concentration of 4-hydroxy hexenal increases heme oxygenase-1 expression through activation of Nrf2 and antioxidative activity in vascular endothelial cells Biochem. Biophys. Res. Commun. 402 2010 99 104
    • (2010) Biochem. Biophys. Res. Commun. , vol.402 , pp. 99-104
    • Ishikado, A.1    Nishio, Y.2    Morino, K.3    Ugi, S.4    Kondo, H.5    Makino, T.6    Kashiwagi, A.7    Maegawa, H.8
  • 13
    • 1642396537 scopus 로고    scopus 로고
    • Role of Nrf2 in the Regulation of CD36 and Stress Protein Expression in Murine Macrophages: Activation by Oxidatively Modified LDL and 4-Hydroxynonenal
    • DOI 10.1161/01.RES.0000119171.44657.45
    • T. Ishii, K. Itoh, E. Ruiz, D.S. Leake, H. Unoki, M. Yamamoto, and G.E. Mann Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal Circ. Res. 94 2004 609 616 (Pubitemid 38387743)
    • (2004) Circulation Research , vol.94 , Issue.5 , pp. 609-616
    • Ishii, T.1    Itoh, K.2    Ruiz, E.3    Leake, D.S.4    Unoki, H.5    Yamamoto, M.6    Mann, G.E.7
  • 14
    • 29644437160 scopus 로고    scopus 로고
    • 4-Hydroxynonenal induces adaptive response and enhances PC12 cell tolerance primarily through induction of thioredoxin reductase 1 via activation of Nrf2
    • DOI 10.1074/jbc.M508556200
    • Z.H. Chen, Y. Saito, Y. Yoshida, A. Sekine, N. Noguchi, and E. Niki 4-Hydroxynonenal induces adaptive response and enhances PC12 cell tolerance primarily through induction of thioredoxin reductase 1 via activation of Nrf2 J. Biol. Chem. 280 2005 41921 41927 (Pubitemid 43023161)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.51 , pp. 41921-41927
    • Chen, Z.-H.1    Saito, Y.2    Yoshida, Y.3    Sekine, A.4    Noguchi, N.5    Niki, E.6
  • 15
    • 84870920138 scopus 로고    scopus 로고
    • Anti-oxidative stress regulator NF-E2-related factor 2 mediates the adaptive induction of antioxidant and detoxifying enzymes by lipid peroxidation metabolite 4-hydroxynonenal
    • Y. Huang, W. Li, and A.N. Kong Anti-oxidative stress regulator NF-E2-related factor 2 mediates the adaptive induction of antioxidant and detoxifying enzymes by lipid peroxidation metabolite 4-hydroxynonenal Cell Biosci. 2 2012 40
    • (2012) Cell Biosci. , vol.2 , pp. 40
    • Huang, Y.1    Li, W.2    Kong, A.N.3
  • 16
    • 33744970045 scopus 로고    scopus 로고
    • γ-Glutamyl transpeptidase is induced by 4-hydroxynonenal via EpRE/Nrf2 signaling in rat epithelial type II cells
    • DOI 10.1016/j.freeradbiomed.2005.11.005, PII S0891584905007008
    • H.Q. Zhang, H.L. Liu, D.A. Dickinson, R.M. Liu, E.M. Postlethwait, Y. Laperche, and H.J. Forman γ-Glutamyl transpeptidase is induced by 4-hydroxynonenal via EpRE/Nrf2 signaling in rat epithelial type II cells Free Radic. Biol. Med. 40 2006 1281 1292 (Pubitemid 44316497)
    • (2006) Free Radical Biology and Medicine , vol.40 , Issue.8 , pp. 1281-1292
    • Zhang, H.1    Liu, H.2    Dickinson, D.A.3    Liu, R.-M.4    Postlethwait, E.M.5    Laperche, Y.6    Forman, H.J.7
  • 17
    • 77956234404 scopus 로고    scopus 로고
    • Reactive oxygen species and alpha,beta-unsaturated aldehydes as second messengers in signal transduction
    • H.J. Forman Reactive oxygen species and alpha,beta-unsaturated aldehydes as second messengers in signal transduction Ann. N. Y. Acad. Sci. 1203 2010 35 44
    • (2010) Ann. N. Y. Acad. Sci. , vol.1203 , pp. 35-44
    • Forman, H.J.1
  • 19
    • 45249124663 scopus 로고    scopus 로고
    • 4-Hydroxynonenal: A membrane lipid oxidation product of medicinal interest
    • DOI 10.1002/med.20117
    • G. Poli, R.J. Schaur, W.G. Siems, and G. Leonarduzzi 4-Hydroxynonenal: a membrane lipid oxidation product of medicinal interest Med. Res. Rev. 28 2008 569 631 (Pubitemid 351842143)
    • (2008) Medicinal Research Reviews , vol.28 , Issue.4 , pp. 569-631
    • Poli, G.1    Schaur, R.J.2    Siems, W.G.3    Leonarduzzi, G.4
  • 20
    • 84893273332 scopus 로고    scopus 로고
    • 4-Hydroxynonenal in the pathogenesis and progression of human diseases
    • M. Shoeb, N.H. Ansari, S.K. Srivastava, and K.V. Ramana 4-Hydroxynonenal in the pathogenesis and progression of human diseases Curr. Med. Chem. 21 2013 230 237
    • (2013) Curr. Med. Chem. , vol.21 , pp. 230-237
    • Shoeb, M.1    Ansari, N.H.2    Srivastava, S.K.3    Ramana, K.V.4
  • 23
    • 41149143613 scopus 로고    scopus 로고
    • Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice
    • DOI 10.1021/bi702124u
    • S.P. Singh, M. Niemczyk, D. Saini, Y.C. Awasthi, L. Zimniak, and P. Zimniak Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice Biochemistry 47 2008 3900 3911 (Pubitemid 351431379)
    • (2008) Biochemistry , vol.47 , Issue.12 , pp. 3900-3911
    • Singh, S.P.1    Niemczyk, M.2    Saini, D.3    Awasthi, Y.C.4    Zimniak, L.5    Zimniak, P.6
  • 24
    • 79956155956 scopus 로고    scopus 로고
    • Structural and functional changes in human insulin induced by the lipid peroxidation byproducts 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenal
    • N.J. Pillon, R.E. Vella, L. Souleere, M. Becchi, M. Lagarde, and C.O. Soulage Structural and functional changes in human insulin induced by the lipid peroxidation byproducts 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenal Chem. Res. Toxicol. 24 2011 752 762
    • (2011) Chem. Res. Toxicol. , vol.24 , pp. 752-762
    • Pillon, N.J.1    Vella, R.E.2    Souleere, L.3    Becchi, M.4    Lagarde, M.5    Soulage, C.O.6
  • 25
    • 84860338652 scopus 로고    scopus 로고
    • The lipid peroxidation by-product 4-hydroxy-2-nonenal (4-HNE) induces insulin resistance in skeletal muscle through both carbonyl and oxidative stress
    • N.J. Pillon, M.L. Croze, R.E. Vella, L. Soulère, M. Lagarde, and C.O. Soulage The lipid peroxidation by-product 4-hydroxy-2-nonenal (4-HNE) induces insulin resistance in skeletal muscle through both carbonyl and oxidative stress Endocrinology 153 2012 2099 2111
    • (2012) Endocrinology , vol.153 , pp. 2099-2111
    • Pillon, N.J.1    Croze, M.L.2    Vella, R.E.3    Soulère, L.4    Lagarde, M.5    Soulage, C.O.6
  • 26
    • 0034464215 scopus 로고    scopus 로고
    • Inhibition of glucose-induced insulin secretion by 4-hydroxy-2-nonenal and other lipid peroxidation products
    • DOI 10.1210/en.141.8.2767
    • I. Miwa, N. Ichimura, M. Sugiura, Y. Hamada, and S. Taniguchi Inhibition of glucose-induced insulin secretion by 4-hydroxy-2-nonenal and other lipid peroxidation products Endocrinology 141 2000 2767 2772 (Pubitemid 32250437)
    • (2000) Endocrinology , vol.141 , Issue.8 , pp. 2767-2772
    • Miwa, I.1    Ichimura, N.2    Sugiura, M.3    Hamada, Y.4    Taniguchi, S.5
  • 27
    • 7444224175 scopus 로고    scopus 로고
    • Signaling kinases modulated by 4-hydroxynonenal
    • DOI 10.1016/j.freeradbiomed.2004.08.027, PII S0891584904006884
    • G. Leonarduzzi, F. Robbesyn, and G. Poli Signaling kinases modulated by 4-hydroxynonenal Free Radic. Biol. Med. 37 2004 1694 1702 (Pubitemid 39445371)
    • (2004) Free Radical Biology and Medicine , vol.37 , Issue.11 , pp. 1694-1702
    • Leonarduzzi, G.1    Robbesyn, F.2    Poli, G.3
  • 28
    • 34247361278 scopus 로고    scopus 로고
    • Carbonylation of adipose proteins in obesity and insulin resistance: Identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal
    • DOI 10.1074/mcp.M600120-MCP200
    • P.A. Grimsrud, M.J. Picklo, T.J. Griffin, and D.A. Bernlohr Carbonylation of adipose proteins in obesity and insulin resistance: identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal Mol. Cell. Proteomics 6 2007 624 637 (Pubitemid 46630095)
    • (2007) Molecular and Cellular Proteomics , vol.6 , Issue.4 , pp. 624-637
    • Grimsrud, P.A.1    Picklo Sr., M.J.2    Griffin, T.J.3    Bernlohr, D.A.4
  • 30
    • 84881096859 scopus 로고    scopus 로고
    • Increased 4-hydroxynonenal formation contributes to obesity-related lipolytic activation in adipocytes
    • X. Zhang, Z. Wang, J. Li, D. Gu, S. Li, C. Shen, and Z. Song Increased 4-hydroxynonenal formation contributes to obesity-related lipolytic activation in adipocytes PLoS One 8 2013 e70663
    • (2013) PLoS One , vol.8 , pp. 70663
    • Zhang, X.1    Wang, Z.2    Li, J.3    Gu, D.4    Li, S.5    Shen, C.6    Song, Z.7
  • 32
    • 0027519515 scopus 로고
    • Immunostaining of human autopsy aortas with antibodies to modified apolipoprotein B and apoprotein(a)
    • G. Jürgens, Q. Chen, H. Esterbauer, S. Mair, G. Ledinski, and H.P. Dinges Immunostaining of human autopsy aortas with antibodies to modified apolipoprotein B and apoprotein(a) Arterioscler. Thromb. 13 1993 1689 1699 (Pubitemid 23328490)
    • (1993) Arteriosclerosis and Thrombosis , vol.13 , Issue.11 , pp. 1689-1699
    • Jurgens, G.1    Chen, Q.2    Esterbauer, H.3    Mair, S.4    Ledinski, G.5    Dinges, H.P.6
  • 34
    • 36348954964 scopus 로고    scopus 로고
    • Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion
    • DOI 10.2353/ajpath.2007.070218
    • Y.M. Go, P.J. Halvey, J.M. Hansen, M. Reed, J. Pohl, and D.P. Jones Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion Am. J. Pathol. 171 2007 1670 1681 (Pubitemid 350158327)
    • (2007) American Journal of Pathology , vol.171 , Issue.5 , pp. 1670-1681
    • Go, Y.-M.1    Halvey, P.J.2    Hansen, J.M.3    Reed, M.4    Pohl, J.5    Jones, D.P.6
  • 35
    • 84879070907 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal enhances tissue factor activity in human monocytic cells via p38 mitogen-activated protein kinase activation-dependent phosphatidylserine exposure
    • R. Vatsyayan, H. Kothari, U.R. Pendurthi, and L.V. Rao 4-Hydroxy-2-nonenal enhances tissue factor activity in human monocytic cells via p38 mitogen-activated protein kinase activation-dependent phosphatidylserine exposure Arterioscler. Thromb. Vasc. Biol. 33 2013 1601 1611
    • (2013) Arterioscler. Thromb. Vasc. Biol. , vol.33 , pp. 1601-1611
    • Vatsyayan, R.1    Kothari, H.2    Pendurthi, U.R.3    Rao, L.V.4
  • 36
    • 23844442198 scopus 로고    scopus 로고
    • Cysteine modification by lipid peroxidation products inhibits protein disulfide isomerase
    • DOI 10.1021/tx050078z
    • D.L. Carbone, J.A. Doorn, Z. Kiebler, and D.R. Petersen Cysteine modification by lipid peroxidation products inhibits protein disulfide isomerase Chem. Res. Toxicol. 18 2005 1324 1331 (Pubitemid 41174583)
    • (2005) Chemical Research in Toxicology , vol.18 , Issue.8 , pp. 1324-1331
    • Carbone, D.L.1    Doorn, J.A.2    Kiebler, Z.3    Petersen, D.R.4
  • 38
    • 84866848255 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neurodegenerative diseases: A toxic combination illuminated by redox proteomics studies
    • M. Perluigi, R. Coccia, and D.A. Butterfield 4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neurodegenerative diseases: a toxic combination illuminated by redox proteomics studies Antioxid. Redox Signaling 17 2012 1590 1609
    • (2012) Antioxid. Redox Signaling , vol.17 , pp. 1590-1609
    • Perluigi, M.1    Coccia, R.2    Butterfield, D.A.3
  • 39
    • 84884877254 scopus 로고    scopus 로고
    • Lipid peroxidation triggers neurodegeneration: A redox proteomics view into the Alzheimer disease brain
    • R. Sultana, M. Perluigi, and D. Allan Butterfield Lipid peroxidation triggers neurodegeneration: a redox proteomics view into the Alzheimer disease brain Free Radic. Biol. Med. 62 2013 157 169
    • (2013) Free Radic. Biol. Med. , vol.62 , pp. 157-169
    • Sultana, R.1    Perluigi, M.2    Allan Butterfield, D.3
  • 42
    • 85005814220 scopus 로고    scopus 로고
    • The link between intraneuronal N-truncated amyloid-β peptide and oxidatively modified lipids in idiopathic autism and dup(15q11.2-q13)/autism
    • J. Frackowiak, B. Mazur-Kolecka, N.C. Schanen, W.T. Brown, and J. Wegiel The link between intraneuronal N-truncated amyloid-β peptide and oxidatively modified lipids in idiopathic autism and dup(15q11.2-q13)/autism Acta Neuropathol. Commun. 1 2013 61
    • (2013) Acta Neuropathol. Commun. , vol.1 , pp. 61
    • Frackowiak, J.1    Mazur-Kolecka, B.2    Schanen, N.C.3    Brown, W.T.4    Wegiel, J.5
  • 46
    • 19544387017 scopus 로고    scopus 로고
    • II-mediated decomposition of a linoleic acid-derived lipid hydroperoxide by liquid chromatography/mass spectrometry
    • DOI 10.1002/jms.838
    • S. Lee, T. Oe, J. Arora, and I. Blair Analysis of Fe(II)-mediated decomposition of a linoleic acid-derived lipid hydroperoxide by liquid chromatography/mass spectrometry J. Mass Spectrom. 40 2005 661 668 (Pubitemid 40733324)
    • (2005) Journal of Mass Spectrometry , vol.40 , Issue.5 , pp. 661-668
    • Lee, S.H.1    Oe, T.2    Arora, J.S.3    Blair, I.A.4
  • 47
    • 0033520879 scopus 로고    scopus 로고
    • Mode of action of sesame lignans in protecting low-density lipoprotein against oxidative damage in vitro
    • PII S0024320599005743
    • M.H. Kang, M. Naito, K. Sakai, K. Uchida, and T. Osawa Mode of action of sesame lignans in protecting low-density lipoprotein against oxidative damage in vitro Life Sci. 66 2000 161 171 (Pubitemid 30025463)
    • (2000) Life Sciences , vol.66 , Issue.2 , pp. 161-171
    • Kang, M.-H.1    Naito, M.2    Sakai, K.3    Uchida, K.4    Osawa, T.5
  • 48
    • 34548393689 scopus 로고    scopus 로고
    • Inhibition of lipid peroxidation induced by hydroxyprogesterone caproate by some conventional antioxidants in goat liver homogenates
    • K. De, K. Roy, and C. Sengupta Inhibition of lipid peroxidation induced by hydroxyprogesterone caproate by some conventional antioxidants in goat liver homogenates Acta Pol. Pharm 64 2007 201 210 (Pubitemid 351360421)
    • (2007) Acta Poloniae Pharmaceutica - Drug Research , vol.64 , Issue.3 , pp. 201-210
    • De, K.1    Roy, K.2    Sengupta, C.3
  • 50
    • 49649128383 scopus 로고    scopus 로고
    • A dose-response study on the effects of purified lycopene supplementation on biomarkers of oxidative stress
    • S. Devaraj, S. Mathur, A. Basu, H.H. Aung, V.T. Vasu, S. Meyers, and I. Jialal A dose-response study on the effects of purified lycopene supplementation on biomarkers of oxidative stress J. Am. Coll. Nutr. 27 2008 267 273
    • (2008) J. Am. Coll. Nutr. , vol.27 , pp. 267-273
    • Devaraj, S.1    Mathur, S.2    Basu, A.3    Aung, H.H.4    Vasu, V.T.5    Meyers, S.6    Jialal, I.7
  • 51
    • 67649908957 scopus 로고    scopus 로고
    • Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells
    • C.L. Miranda, R.L. Reed, H.C. Kuiper, S. Alber, and J.F. Stevens Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells Chem. Res. Toxicol. 22 2009 863 874
    • (2009) Chem. Res. Toxicol. , vol.22 , pp. 863-874
    • Miranda, C.L.1    Reed, R.L.2    Kuiper, H.C.3    Alber, S.4    Stevens, J.F.5
  • 52
    • 33746549327 scopus 로고    scopus 로고
    • Neuroprotective effects of edaravone: A novel free radical scavenger in cerebrovascular injury
    • DOI 10.1111/j.1527-3458.2006.00009.x
    • H. Yoshida, H. Yanai, Y. Namiki, K. Fukatsu-Sasaki, N. Furutani, and N. Tada Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury CNS Drug Rev. 12 2006 9 20 (Pubitemid 44133577)
    • (2006) CNS Drug Reviews , vol.12 , Issue.1 , pp. 9-20
    • Yoshida, H.1    Yanai, H.2    Namiki, Y.3    Fukatsu-Sasaki, K.4    Furutani, N.5    Tada, N.6
  • 53
    • 84883044650 scopus 로고    scopus 로고
    • Neuroprotective effects of edaravone on cognitive deficit, oxidative stress and tau hyperphosphorylation induced by intracerebroventricular streptozotocin in rats
    • S. Zhou, G. Yu, L. Chi, J. Zhu, W. Zhang, Y. Zhang, and L. Zhang Neuroprotective effects of edaravone on cognitive deficit, oxidative stress and tau hyperphosphorylation induced by intracerebroventricular streptozotocin in rats Neurotoxicology 38C 2013 136 145
    • (2013) Neurotoxicology , vol.38 C , pp. 136-145
    • Zhou, S.1    Yu, G.2    Chi, L.3    Zhu, J.4    Zhang, W.5    Zhang, Y.6    Zhang, L.7
  • 54
    • 26444613280 scopus 로고    scopus 로고
    • Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain
    • DOI 10.1161/01.STR.0000182241.07096.06
    • N. Zhang, M. Komine-Kobayashi, R. Tanaka, M. Liu, Y. Mizuno, and T. Urabe Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain Stroke 36 2005 2220 2225 (Pubitemid 41429250)
    • (2005) Stroke , vol.36 , Issue.10 , pp. 2220-2225
    • Zhang, N.1    Komine-Kobayashi, M.2    Tanaka, R.3    Liu, M.4    Mizuno, Y.5    Urabe, T.6
  • 55
    • 33947162483 scopus 로고    scopus 로고
    • Potent free radical scavenger, edaravone, suppresses oxidative stress-induced endothelial damage and early atherosclerosis
    • DOI 10.1016/j.atherosclerosis.2006.05.040, PII S0021915006003212
    • H. Xi, M. Akishita, K. Nagai, W. Yu, H. Hasegawa, M. Eto, K. Kozaki, and K. Toba Potent free radical scavenger, edaravone, suppresses oxidative stress-induced endothelial damage and early atherosclerosis Atherosclerosis 191 2007 281 289 (Pubitemid 46400711)
    • (2007) Atherosclerosis , vol.191 , Issue.2 , pp. 281-289
    • Xi, H.1    Akishita, M.2    Nagai, K.3    Yu, W.4    Hasegawa, H.5    Eto, M.6    Kozaki, K.7    Toba, K.8
  • 56
    • 75149193424 scopus 로고    scopus 로고
    • Edaravone inhibits protein carbonylation by a direct carbonyl-scavenging mechanism: Focus on reactivity, selectivity, and reaction mechanisms
    • G. Aldini, G. Vistoli, L. Regazzoni, M.C. Benfatto, I. Bettinelli, and M. Carini Edaravone inhibits protein carbonylation by a direct carbonyl-scavenging mechanism: focus on reactivity, selectivity, and reaction mechanisms Antioxid. Redox Signaling 12 2010 381 392
    • (2010) Antioxid. Redox Signaling , vol.12 , pp. 381-392
    • Aldini, G.1    Vistoli, G.2    Regazzoni, L.3    Benfatto, M.C.4    Bettinelli, I.5    Carini, M.6
  • 58
    • 77956543364 scopus 로고    scopus 로고
    • Green tea supplementation affects body weight, lipids, and lipid peroxidation in obese subjects with metabolic syndrome
    • A. Basu, K. Sanchez, M.J. Leyva, M. Wu, N.M. Betts, C.E. Aston, and T.J. Lyons Green tea supplementation affects body weight, lipids, and lipid peroxidation in obese subjects with metabolic syndrome J. Am. Coll. Nutr. 29 2010 31 40
    • (2010) J. Am. Coll. Nutr. , vol.29 , pp. 31-40
    • Basu, A.1    Sanchez, K.2    Leyva, M.J.3    Wu, M.4    Betts, N.M.5    Aston, C.E.6    Lyons, T.J.7
  • 59
    • 84880879037 scopus 로고    scopus 로고
    • Pomegranate polyphenols lower lipid peroxidation in adults with type 2 diabetes but have no effects in healthy volunteers: A pilot study
    • A. Basu, E.D. Newman, A.L. Bryant, T.J. Lyons, and N.M. Betts Pomegranate polyphenols lower lipid peroxidation in adults with type 2 diabetes but have no effects in healthy volunteers: a pilot study J. Nutr. Metab 2013 2013 708381
    • (2013) J. Nutr. Metab , vol.2013 , pp. 708381
    • Basu, A.1    Newman, E.D.2    Bryant, A.L.3    Lyons, T.J.4    Betts, N.M.5
  • 60
    • 78650908678 scopus 로고    scopus 로고
    • Modulation of endogenous antioxidant system by wine polyphenols in human disease
    • R. Rodrigo, A. Miranda, and L. Vergara Modulation of endogenous antioxidant system by wine polyphenols in human disease Clin. Chim. Acta 412 2011 410 424
    • (2011) Clin. Chim. Acta , vol.412 , pp. 410-424
    • Rodrigo, R.1    Miranda, A.2    Vergara, L.3
  • 61
    • 84893831553 scopus 로고    scopus 로고
    • LC-MS/MS quantitation of mercapturic acid conjugates of lipid peroxidation products as markers of oxidative stress
    • (Chap. 17:Unit 17.14.12)
    • H.C. Kuiper, and J.F. Stevens LC-MS/MS quantitation of mercapturic acid conjugates of lipid peroxidation products as markers of oxidative stress Curr. Protoc. Toxicol. 2011 (Chap. 17:Unit 17.14.12)
    • (2011) Curr. Protoc. Toxicol.
    • Kuiper, H.C.1    Stevens, J.F.2
  • 62
    • 58149331913 scopus 로고    scopus 로고
    • The biochemistry of drug metabolism - An introduction. Part 4. Reactions of conjugation and their enzymes
    • B. Testa, and S.D. Krämer The biochemistry of drug metabolism - an introduction. Part 4. Reactions of conjugation and their enzymes Chem. Biodiversity 5 2008 2171 2336
    • (2008) Chem. Biodiversity , vol.5 , pp. 2171-2336
    • Testa, B.1    Krämer, S.D.2
  • 64
    • 0034743831 scopus 로고    scopus 로고
    • Substituent effects on the stability of carbodiimides
    • D. Tahmassebi Substituent effects on the stability of carbodiimides J. Chem. Soc. Perkin Trans. 2 4 2001 613 617
    • (2001) J. Chem. Soc. Perkin Trans. , vol.2 , Issue.4 , pp. 613-617
    • Tahmassebi, D.1
  • 65
    • 33646764926 scopus 로고    scopus 로고
    • N-acetylcysteine selectively protects cerebellar granule cells from 4-hydroxynonenal-induced cell death
    • DOI 10.1016/j.neures.2006.03.008, PII S0168010206000691
    • M. Arakawa, N. Ushimaru, N. Osada, T. Oda, K. Ishige, and Y. Ito N-acetylcysteine selectively protects cerebellar granule cells from 4-hydroxynonenal-induced cell death Neurosci. Res. 55 2006 255 263 (Pubitemid 43766414)
    • (2006) Neuroscience Research , vol.55 , Issue.3 , pp. 255-263
    • Arakawa, M.1    Ushimaru, N.2    Osada, N.3    Oda, T.4    Ishige, K.5    Ito, Y.6
  • 66
    • 36549029828 scopus 로고    scopus 로고
    • N-acetylcysteine and neurodegenerative diseases: Basic and clinical pharmacology
    • DOI 10.1080/14734220601142878, PII 770199349
    • M. Arakawa, and Y. Ito N-acetylcysteine and neurodegenerative diseases: basic and clinical pharmacology Cerebellum 6 2007 308 314 (Pubitemid 350179062)
    • (2007) Cerebellum , vol.6 , Issue.4 , pp. 308-314
    • Arakawa, M.1    Ito, Y.2
  • 67
    • 0030854637 scopus 로고    scopus 로고
    • Efficient scavenging of fatty acid oxidation products by aminoguanidine
    • DOI 10.1021/tx970035l
    • Y. Al-Abed, and R. Bucala Efficient scavenging of fatty acid oxidation products by aminoguanidine Chem. Res. Toxicol. 10 1997 875 879 (Pubitemid 27350046)
    • (1997) Chemical Research in Toxicology , vol.10 , Issue.8 , pp. 875-879
    • Al-Abed, Y.1    Bucala, R.2
  • 68
    • 0034669362 scopus 로고    scopus 로고
    • Congeners of N(α)-acetyl-l-cysteine but not aminoguanidine act as neuroprotectants from the lipid peroxidation product 4-hydroxy-2-nonenal
    • M.D. Neely, L. Zimmerman, M.J. Picklo, J.J. Ou, C.R. Morales, and K.S. Montine Amaranth, V.; Montine, T. J. Congeners of N(α)-acetyl-l-cysteine but not aminoguanidine act as neuroprotectants from the lipid peroxidation product 4-hydroxy-2-nonenal Free Radic. Biol. Med. 29 2000 1028 1036
    • (2000) Free Radic. Biol. Med. , vol.29 , pp. 1028-1036
    • Neely, M.D.1    Zimmerman, L.2    Picklo, M.J.3    Ou, J.J.4    Morales, C.R.5    Montine, K.S.6
  • 69
    • 0034107785 scopus 로고    scopus 로고
    • Kinetics and mechanism of the reaction of aminoguanidine with the α-oxoaldehydes glyoxal, methylglyoxal, and 3-deoxyglucosone under physiological conditions
    • DOI 10.1016/S0006-2952(00)00287-2, PII S0006295200002872
    • P.J. Thornalley, A. Yurek-George, and O.K. Argirov Kinetics and mechanism of the reaction of aminoguanidine with the alpha-oxoaldehydes glyoxal, methylglyoxal, and 3-deoxyglucosone under physiological conditions Biochem. Pharmacol. 60 2000 55 65 (Pubitemid 30243085)
    • (2000) Biochemical Pharmacology , vol.60 , Issue.1 , pp. 55-65
    • Thornalley, P.J.1    Yurek-George, A.2    Argirov, O.K.3
  • 70
    • 0142074864 scopus 로고    scopus 로고
    • Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts
    • DOI 10.1016/j.abb.2003.08.013
    • P.J. Thornalley Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts Arch. Biochem. Biophys 419 2003 31 40 (Pubitemid 37279141)
    • (2003) Archives of Biochemistry and Biophysics , vol.419 , Issue.1 , pp. 31-40
    • Thornalley, P.J.1
  • 72
    • 0034647739 scopus 로고    scopus 로고
    • Pyridoxamine, an inhibitor of advanced glycation reactions, inhibits advanced lipoxidation reactions: Mechanism of action of pyridoxamine
    • DOI 10.1074/jbc.M003263200
    • J.M. Onorato, A.J. Jenkins, S.R. Thorpe, and J.W. Baynes Pyridoxamine, an inhibitor of advanced glycation reactions, also inhibits advanced lipoxidation reactions: mechanism of action of pyridoxamine J. Biol. Chem. 275 2000 21177 21184 (Pubitemid 30481811)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.28 , pp. 21177-21184
    • Onorato, J.M.1    Jenkins, A.J.2    Thorpe, S.R.3    Baynes, J.W.4
  • 73
    • 0142211275 scopus 로고    scopus 로고
    • Pyridoxamine traps intermediates in lipid peroxidation reactions in vivo: Evidence on the role of lipids in chemical modification of protein and development of diabetic complications
    • DOI 10.1074/jbc.M304292200
    • T.O. Metz, N.L. Alderson, M.E. Chachich, S.R. Thorpe, and J.W. Baynes Pyridoxamine traps intermediates in lipid peroxidation reactions in vivo: evidence on the role of lipids in chemical modification of protein and development of diabetic complications J. Biol. Chem. 278 2003 42012 42019 (Pubitemid 37310465)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.43 , pp. 42012-42019
    • Metz, T.O.1    Alderson, N.L.2    Chachich, M.E.3    Thorpe, S.R.4    Baynes, J.W.5
  • 74
    • 23844460628 scopus 로고    scopus 로고
    • Pyridoxamine as a multifunctional pharmaceutical: Targeting pathogenic glycation and oxidative damage
    • DOI 10.1007/s00018-005-5082-7
    • P.A. Voziyan, and B.G. Hudson Pyridoxamine as a multifunctional pharmaceutical: targeting pathogenic glycation and oxidative damage Cell Mol. Life Sci. 62 2005 1671 1681 (Pubitemid 41176049)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.15 , pp. 1671-1681
    • Voziyan, P.A.1    Hudson, B.G.2
  • 75
    • 84862118638 scopus 로고    scopus 로고
    • Update on potential drugs for the treatment of diabetic kidney disease
    • B. Shepler, C. Nash, C. Smith, A. DiMarco, J. Petty, and S. Szewciw Update on potential drugs for the treatment of diabetic kidney disease Clin. Ther. 34 2012 1237 1246
    • (2012) Clin. Ther. , vol.34 , pp. 1237-1246
    • Shepler, B.1    Nash, C.2    Smith, C.3    Dimarco, A.4    Petty, J.5    Szewciw, S.6
  • 78
    • 33645741763 scopus 로고    scopus 로고
    • Desensitization of platelet-derived growth factor receptor-beta by oxidized lipids in vascular cells and atherosclerotic lesions: Prevention by aldehyde scavengers
    • C. Vindis, I. Escargueil-Blanc, M. Elbaz, B. Marcheix, M.H. Grazide, K. Uchida, R. Salvayre, and A. Nègre-Salvayre Desensitization of platelet-derived growth factor receptor-beta by oxidized lipids in vascular cells and atherosclerotic lesions: prevention by aldehyde scavengers Circ. Res. 98 2006 785 792
    • (2006) Circ. Res. , vol.98 , pp. 785-792
    • Vindis, C.1    Escargueil-Blanc, I.2    Elbaz, M.3    Marcheix, B.4    Grazide, M.H.5    Uchida, K.6    Salvayre, R.7    Nègre-Salvayre, A.8
  • 79
    • 42949163044 scopus 로고    scopus 로고
    • Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury
    • DOI 10.2174/138955708783955953
    • P.C. Burcham, L.M. Kaminskas, D. Tan, and S.M. Pyke Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury Mini Rev. Med. Chem. 8 2008 319 330 (Pubitemid 351606774)
    • (2008) Mini-Reviews in Medicinal Chemistry , vol.8 , Issue.4 , pp. 319-330
    • Burcham, P.C.1    Kaminskas, L.M.2    Tan, D.3    Pyke, S.M.4
  • 80
    • 67049097541 scopus 로고    scopus 로고
    • Design, synthesis, and evaluation of carnosine derivatives as selective and efficient sequestering agents of cytotoxic reactive carbonyl species
    • G. Vistoli, M. Orioli, A. Pedretti, L. Regazzoni, R. Canevotti, G. Negrisoli, M. Carini, and G. Aldini Design, synthesis, and evaluation of carnosine derivatives as selective and efficient sequestering agents of cytotoxic reactive carbonyl species ChemMedChem 4 2009 967 975
    • (2009) ChemMedChem , vol.4 , pp. 967-975
    • Vistoli, G.1    Orioli, M.2    Pedretti, A.3    Regazzoni, L.4    Canevotti, R.5    Negrisoli, G.6    Carini, M.7    Aldini, G.8
  • 82
    • 84885711135 scopus 로고    scopus 로고
    • Physiology and pathophysiology of carnosine
    • A.A. Boldyrev, G. Aldini, and W. Derave Physiology and pathophysiology of carnosine Physiol. Rev. 93 2013 1803 1845
    • (2013) Physiol. Rev. , vol.93 , pp. 1803-1845
    • Boldyrev, A.A.1    Aldini, G.2    Derave, W.3
  • 83
    • 0036931210 scopus 로고    scopus 로고
    • Detoxification of cytotoxic α,Β-unsaturated aldehydes by carnosine: Characterization of conjugated adducts by electrospray ionization tandem mass spectrometry and detection by liquid chromatography/mass spectrometry in rat skeletal muscle
    • DOI 10.1002/jms.381
    • G. Aldini, P. Granata, and M. Carini Detoxification of cytotoxic alpha,beta-unsaturated aldehydes by carnosine: characterization of conjugated adducts by electrospray ionization tandem mass spectrometry and detection by liquid chromatography/mass spectrometry in rat skeletal muscle J. Mass Spectrom. 37 2002 1219 1228 (Pubitemid 36041609)
    • (2002) Journal of Mass Spectrometry , vol.37 , Issue.12 , pp. 1219-1228
    • Aldini, G.1    Granata, P.2    Carini, M.3
  • 85
    • 84862900681 scopus 로고    scopus 로고
    • Predicting the physicochemical profile of diastereoisomeric histidine-containing dipeptides by property space analysis
    • G. Vistoli, V. Straniero, A. Pedretti, L. Fumagalli, C. Bolchi, M. Pallavicini, E. Valoti, and B. Testa Predicting the physicochemical profile of diastereoisomeric histidine-containing dipeptides by property space analysis Chirality 24 2012 566 576
    • (2012) Chirality , vol.24 , pp. 566-576
    • Vistoli, G.1    Straniero, V.2    Pedretti, A.3    Fumagalli, L.4    Bolchi, C.5    Pallavicini, M.6    Valoti, E.7    Testa, B.8
  • 86
    • 27644525132 scopus 로고    scopus 로고
    • LC-ESI-MS/MS determination of 4-hydroxy-trans-2-nonenal Michael adducts with cysteine and histidine-containing peptides as early markers of oxidative stress in excitable tissues
    • DOI 10.1016/j.jchromb.2005.04.025, PII S1570023205003077, Analysis of Antioxidants and Biomarkers of Oxidative Stress
    • M. Orioli, G. Aldini, G. Beretta, R.M. Facino, and M. Carini LC-ESI-MS/MS determination of 4-hydroxy-trans-2-nonenal Michael adducts with cysteine and histidine-containing peptides as early markers of oxidative stress in excitable tissues J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 827 2005 109 118 (Pubitemid 41551604)
    • (2005) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.827 , Issue.1 , pp. 109-118
    • Orioli, M.1    Aldini, G.2    Beretta, G.3    Facino, R.M.4    Carini, M.5
  • 89
    • 84862772594 scopus 로고    scopus 로고
    • Role of l-carnosine in the control of blood glucose, blood pressure, thermogenesis, and lipolysis by autonomic nerves in rats: Involvement of the circadian clock and histamine
    • K. Nagai, M. Tanida, A. Niijima, N. Tsuruoka, Y. Kiso, Y. Horii, J. Shen, and N. Okumura Role of l-carnosine in the control of blood glucose, blood pressure, thermogenesis, and lipolysis by autonomic nerves in rats: involvement of the circadian clock and histamine Amino Acids 43 2012 97 109
    • (2012) Amino Acids , vol.43 , pp. 97-109
    • Nagai, K.1    Tanida, M.2    Niijima, A.3    Tsuruoka, N.4    Kiso, Y.5    Horii, Y.6    Shen, J.7    Okumura, N.8
  • 93
    • 79954621602 scopus 로고    scopus 로고
    • Interactions of glutathione transferases with 4-hydroxynonenal
    • L.M. Balogh, and W.M. Atkins Interactions of glutathione transferases with 4-hydroxynonenal Drug Metab. Rev. 43 2011 165 178
    • (2011) Drug Metab. Rev. , vol.43 , pp. 165-178
    • Balogh, L.M.1    Atkins, W.M.2
  • 94
    • 0041669529 scopus 로고    scopus 로고
    • Fate of 4-hydroxynonenal in vivo: Disposition and metabolic pathways
    • DOI 10.1016/S0098-2997(03)00012-8
    • J. Alary, F. Gueraud, and J.-P. Cravedi Fate of 4-hydroxynonenal in vivo: disposition and metabolic pathways Mol. Aspects Med. 24 2003 177 187 (Pubitemid 36945018)
    • (2003) Molecular Aspects of Medicine , vol.24 , Issue.4-5 , pp. 177-187
    • Alary, J.1    Gueraud, F.2    Cravedi, J.-P.3
  • 96
    • 80053958401 scopus 로고    scopus 로고
    • Preconditioning with physiological levels of ethanol protect kidney against ischemia/reperfusion injury by modulating oxidative stress
    • Q. Yuan, S. Hong, S. Han, L. Zeng, F. Liu, G. Ding, Y. Kang, J. Mao, M. Cai, Y. Zhu, and Q.X. Wang Preconditioning with physiological levels of ethanol protect kidney against ischemia/reperfusion injury by modulating oxidative stress PLoS One 6 2011 e25811
    • (2011) PLoS One , vol.6 , pp. 25811
    • Yuan, Q.1    Hong, S.2    Han, S.3    Zeng, L.4    Liu, F.5    Ding, G.6    Kang, Y.7    Mao, J.8    Cai, M.9    Zhu, Y.10    Wang, Q.X.11
  • 97
    • 58149302706 scopus 로고    scopus 로고
    • Time-dependent and ethanol-induced cardiac protection from ischemia mediated by mitochondrial translocation of varepsilonPKC and activation of aldehyde dehydrogenase 2
    • E.N. Churchill, M.H. Disatnik, and D. Mochly-Rosen Time-dependent and ethanol-induced cardiac protection from ischemia mediated by mitochondrial translocation of varepsilonPKC and activation of aldehyde dehydrogenase 2 J. Mol. Cell. Cardiol. 46 2009 278 284
    • (2009) J. Mol. Cell. Cardiol. , vol.46 , pp. 278-284
    • Churchill, E.N.1    Disatnik, M.H.2    Mochly-Rosen, D.3
  • 98
    • 77951472369 scopus 로고    scopus 로고
    • Cardioprotection by regular ethanol consumption: Potential mechanisms and clinical application
    • M. Miyamae, K. Kaneda, N. Domae, and V.M. Figueredo Cardioprotection by regular ethanol consumption: potential mechanisms and clinical application Curr. Drug Abuse Rev. 3 2010 39 48
    • (2010) Curr. Drug Abuse Rev. , vol.3 , pp. 39-48
    • Miyamae, M.1    Kaneda, K.2    Domae, N.3    Figueredo, V.M.4
  • 100
    • 77649273950 scopus 로고    scopus 로고
    • Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCvarepsilon) knockout mice
    • G.R. Budas, M.H. Disatnik, C.H. Chen, and D. Mochly-Rosen Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCvarepsilon) knockout mice J. Mol. Cell. Cardiol. 48 2010 757 764
    • (2010) J. Mol. Cell. Cardiol. , vol.48 , pp. 757-764
    • Budas, G.R.1    Disatnik, M.H.2    Chen, C.H.3    Mochly-Rosen, D.4
  • 101
    • 31844443064 scopus 로고    scopus 로고
    • Inhibition of human mitochondrial aldehyde dehydrogenase by 4-hydroxynon-2-enal and 4-oxonon-2-enal
    • DOI 10.1021/tx0501839
    • J.A. Doorn, T.D. Hurley, and D.R. Petersen Inhibition of human mitochondrial aldehyde dehydrogenase by 4-hydroxynon-2-enal and 4-oxonon-2-enal Chem. Res. Toxicol. 19 2006 102 110 (Pubitemid 43185467)
    • (2006) Chemical Research in Toxicology , vol.19 , Issue.1 , pp. 102-110
    • Doorn, J.A.1    Hurley, T.D.2    Petersen, D.R.3
  • 102
    • 84862781173 scopus 로고    scopus 로고
    • Alpha lipoic acid protects heart against myocardial ischemia-reperfusion injury through a mechanism involving aldehyde dehydrogenase 2 activation
    • L. He, B. Liu, Z. Dai, H.F. Zhang, Y.S. Zhang, X.J. Luo, Q.L. Ma, and J. Peng Alpha lipoic acid protects heart against myocardial ischemia-reperfusion injury through a mechanism involving aldehyde dehydrogenase 2 activation Eur. J. Pharmacol. 678 2012 32 38
    • (2012) Eur. J. Pharmacol. , vol.678 , pp. 32-38
    • He, L.1    Liu, B.2    Dai, Z.3    Zhang, H.F.4    Zhang, Y.S.5    Luo, X.J.6    Ma, Q.L.7    Peng, J.8
  • 103
    • 19444379739 scopus 로고    scopus 로고
    • Nrf2 as a novel molecular target for chemoprevention
    • J.S. Lee, and Y.J. Surh Nrf2 as a novel molecular target for chemoprevention Cancer Lett. 224 2005 171 184
    • (2005) Cancer Lett. , vol.224 , pp. 171-184
    • Lee, J.S.1    Surh, Y.J.2
  • 104
    • 84874633349 scopus 로고    scopus 로고
    • Administration of the Nrf2-ARE activators sulforaphane and carnosic acid attenuates 4-hydroxy-2-nonenal-induced mitochondrial dysfunction ex vivo
    • D.M. Miller, I.N. Singh, J.A. Wang, and E.D. Hall Administration of the Nrf2-ARE activators sulforaphane and carnosic acid attenuates 4-hydroxy-2-nonenal-induced mitochondrial dysfunction ex vivo Free Radic. Biol. Med. 57 2013 1 9
    • (2013) Free Radic. Biol. Med. , vol.57 , pp. 1-9
    • Miller, D.M.1    Singh, I.N.2    Wang, J.A.3    Hall, E.D.4
  • 106
    • 79957557698 scopus 로고    scopus 로고
    • Differences in glyoxal and methylglyoxal metabolism determine cellular susceptibility to protein carbonylation and cytotoxicity
    • K. Yang, D. Qiang, S. Delaney, R. Mehta, W.R. Bruce, and P.J. O Brien Differences in glyoxal and methylglyoxal metabolism determine cellular susceptibility to protein carbonylation and cytotoxicity Chem.-Biol. Interact. 191 2011 322 329
    • (2011) Chem.-Biol. Interact. , vol.191 , pp. 322-329
    • Yang, K.1    Qiang, D.2    Delaney, S.3    Mehta, R.4    Bruce, W.R.5    Brien, P.J.O.6


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