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Volumn 4, Issue 6, 2009, Pages 967-975

Design, synthesis, and evaluation of carnosine derivatives as selective and efficient sequestering agents of cytotoxic reactive carbonyl species

(8) Vistoli, Giulio a Orioli, Marica a Pedretti, Alessandro a Regazzoni, Luca a Canevotti, Renato b Negrisoli, Gianpaolo b Carini, Marina a Aldini, Giancarlo a

a UNIVERSITY OF MILAN (Italy)

b Flamma SpA (Italy)

Author keywords

Carnosine; Mass spectrometry; Molecular modeling; RCS sequestering agents; Reactive carbonyl species

Indexed keywords

4 HYDROXYNONENAL; AMINOACYLHISTIDINE DIPEPTIDASE; AMINOGUANIDINE; ANTIOXIDANT; CARNOSINE; CARNOSINE DERIVATIVE; DEXTRO CARNOSINE; DIPEPTIDASE; HYDRALAZINE; OXIDIZING AGENT; PYRIDOXAMINE; REACTIVE CARBONYL METABOLITE; UNCLASSIFIED DRUG;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CONFORMATION; DRUG DESIGN; DRUG SELECTIVITY; DRUG STABILITY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ISOMERIZATION; MASS SPECTROMETRY; MOLECULAR MODEL; NORMAL HUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SERUM; STRUCTURE ACTIVITY RELATION;

ACROLEIN; ALDEHYDES; CARNOSINE; CHELATING AGENTS; DIPEPTIDASES; DRUG DESIGN; DRUG STABILITY; FATTY ACIDS, UNSATURATED; HUMANS; LIPID PEROXIDATION; PHYSICOCHEMICAL PROCESSES;

EID: 67049097541 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200800433 Document Type: Article

Times cited : (61)

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