Inhibition of human mitochondrial aldehyde dehydrogenase by 4-hydroxynon-2-enal and 4-oxonon-2-enal

Chemical Research in Toxicology

Volumn 19, Issue 1, 2006, Pages 102-110

  Doorn, Jonathan A ^a   Hurley, Thomas D ^b   Petersen, Dennis R ^c  

^a UNIVERSITY OF IOWA   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; 4 OXONON 2 ENAL; 4 OXONON 2 ENOIC ACID; ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE INHIBITOR; MITOCHONDRIAL ENZYME; UNCLASSIFIED DRUG;

CATALYSIS; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONFERENCE PAPER; COVALENT BOND; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME MODIFICATION; GLUTATHIONE METABOLISM; HUMAN; LIPID PEROXIDATION; MITOCHONDRIAL RESPIRATION; OXIDATION KINETICS;

ALDEHYDE DEHYDROGENASE; ALDEHYDES; ALKYLATION; BINDING SITES; ENZYME INHIBITORS; FATTY ACIDS, UNSATURATED; GLUTATHIONE; HUMANS; KINETICS; MITOCHONDRIA; NAD; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; RECOMBINANT PROTEINS; TRYPSIN;

EID: 31844443064     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0501839     Document Type: Conference Paper

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