Role of aldose reductase in the metabolism and detoxification of carnosine-acrolein conjugates

Journal of Biological Chemistry

Volumn 288, Issue 39, 2013, Pages 28163-28179

  Baba, Shahid P ^a,b   Hoetker, Joseph David ^a,b   Merchant, Michael ^b   Klein, Jon B ^b   Cai, Jian ^b   Barski, Oleg A ^a,b   Conklin, Daniel J ^a,b   Bhatnagar, Aruni ^a,b  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSE REDUCTASE; DI-PEPTIDES; LIPID PEROXIDATION; TISSUE INJURY; UNSATURATED ALDEHYDES;

DETOXIFICATION; PROTEINS;

ALDEHYDES;

ACROLEIN; ALDEHYDE REDUCTASE; CARNOSINE; NUCLEOPHILE; PROPANOL; PROPIONALDEHYDE;

AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CATALYSIS; CONTROLLED STUDY; DETOXIFICATION; EX VIVO STUDY; HEART; HUMAN; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METABOLISM; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CARNOSINYLATION; PROTEIN MODIFICATION; REDUCTION; REPERFUSION INJURY; SKELETAL MUSCLE; TISSUE DISTRIBUTION; URINARY EXCRETION;

BRAIN METABOLISM; CARDIAC METABOLISM; ISCHEMIA; METABOLISM; POST TRANSLATIONAL MODIFICATION; PROTEIN CHEMICAL MODIFICATION; PROTEIN CROSS-LINKING; SKELETAL MUSCLE;

ACETYLCYSTEINE; ACROLEIN; ALDEHYDE REDUCTASE; ANIMALS; ANTIOXIDANTS; CARNOSINE; HUMANS; INFLAMMATION; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; REPERFUSION INJURY; TISSUE DISTRIBUTION;

EID: 84884784140     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.504753     Document Type: Article

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