-
1
-
-
0025078156
-
Effects of L-dopa on extracellular dopamine in striatum of normal and 6-hydroxydopamine-treated rats
-
Abercrombie E.D., Bonatz A.E., Zigmond M.J. Effects of L-dopa on extracellular dopamine in striatum of normal and 6-hydroxydopamine-treated rats. Brain Res. 1990, 525:36-44.
-
(1990)
Brain Res.
, vol.525
, pp. 36-44
-
-
Abercrombie, E.D.1
Bonatz, A.E.2
Zigmond, M.J.3
-
2
-
-
80051855181
-
Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro in cultured macrophages and lipoproteins
-
Aviram M., Volkova N., Coleman R., Dreher M., Reddy M.K., Ferreira D., Rosenblat M. Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro in cultured macrophages and lipoproteins. J. Agric. Food Chem. 2008, 56:1148-1157.
-
(2008)
J. Agric. Food Chem.
, vol.56
, pp. 1148-1157
-
-
Aviram, M.1
Volkova, N.2
Coleman, R.3
Dreher, M.4
Reddy, M.K.5
Ferreira, D.6
Rosenblat, M.7
-
3
-
-
80052653019
-
Research strategies in the study of the pro-oxidant nature of polyphenol nutraceuticals
-
Babich H., Schuck A.G., Weisburg J.H., Zuckerbraun H.L. Research strategies in the study of the pro-oxidant nature of polyphenol nutraceuticals. J. Toxicol. 2011, 2011:467305.
-
(2011)
J. Toxicol.
, vol.2011
, pp. 467305
-
-
Babich, H.1
Schuck, A.G.2
Weisburg, J.H.3
Zuckerbraun, H.L.4
-
4
-
-
34547190796
-
Glutathione as a mediator of the in vitro cytotoxicity of a green tea polyphenol extract
-
Babich H., Selevan A.R., Ravkin E.R. Glutathione as a mediator of the in vitro cytotoxicity of a green tea polyphenol extract. Toxicol. Mech. Methods 2007, 17:357-369.
-
(2007)
Toxicol. Mech. Methods
, vol.17
, pp. 357-369
-
-
Babich, H.1
Selevan, A.R.2
Ravkin, E.R.3
-
5
-
-
1542513224
-
Chronic administration of rotenone increases levels of nitric oxide and lipid peroxidation products in rat brain
-
Bashkatova V., Alam M., Vanin A., Schmidt W.J. Chronic administration of rotenone increases levels of nitric oxide and lipid peroxidation products in rat brain. Exp. Neurol. 2004, 186:235-241.
-
(2004)
Exp. Neurol.
, vol.186
, pp. 235-241
-
-
Bashkatova, V.1
Alam, M.2
Vanin, A.3
Schmidt, W.J.4
-
6
-
-
25444474703
-
Mitochondria take center stage in aging and neurodegeneration
-
Beal M.F. Mitochondria take center stage in aging and neurodegeneration. Ann. Neurol. 2005, 58:495-505.
-
(2005)
Ann. Neurol.
, vol.58
, pp. 495-505
-
-
Beal, M.F.1
-
7
-
-
0025189864
-
Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide
-
Beckman J.S., Beckman T.W., Chen J., Marshall P.A., Freeman B.A. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. U. S. A 1990, 87:1620-1624.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A
, vol.87
, pp. 1620-1624
-
-
Beckman, J.S.1
Beckman, T.W.2
Chen, J.3
Marshall, P.A.4
Freeman, B.A.5
-
8
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R., Sherer T.B., MacKenzie G., Garcia-Osuna M., Panov A.V., Greenamyre J.T. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci. 2000, 3:1301-1306.
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
9
-
-
33846565752
-
Prooxidant DNA breakage induced by caffeic acid in human peripheral lymphocytes: involvement of endogenous copper and a putative mechanism for anticancer properties
-
Bhat S.H., Azmi A.S., Hadi S.M. Prooxidant DNA breakage induced by caffeic acid in human peripheral lymphocytes: involvement of endogenous copper and a putative mechanism for anticancer properties. Toxicol. Appl. Pharmacol. 2007, 218:249-255.
-
(2007)
Toxicol. Appl. Pharmacol.
, vol.218
, pp. 249-255
-
-
Bhat, S.H.1
Azmi, A.S.2
Hadi, S.M.3
-
10
-
-
24144453087
-
Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism
-
Block M.L., Hong J.S. Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Prog. Neurobiol. 2005, 76:77-98.
-
(2005)
Prog. Neurobiol.
, vol.76
, pp. 77-98
-
-
Block, M.L.1
Hong, J.S.2
-
11
-
-
0028364696
-
Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease
-
Boka G., Anglade P., Wallach D., Javoy-Agid F., Agid Y., Hirsch E.C. Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease. Neurosci. Lett. 1994, 172:151-154.
-
(1994)
Neurosci. Lett.
, vol.172
, pp. 151-154
-
-
Boka, G.1
Anglade, P.2
Wallach, D.3
Javoy-Agid, F.4
Agid, Y.5
Hirsch, E.C.6
-
12
-
-
77957363916
-
Exogenous antioxidants - Double-edged swords in cellular redox state: Health beneficial effects at physiologic doses versus deleterious effects at high doses
-
Bouayed J., Bohn T. Exogenous antioxidants - Double-edged swords in cellular redox state: Health beneficial effects at physiologic doses versus deleterious effects at high doses. Oxid. Med. Cell Longev. 2010, 3:228-237.
-
(2010)
Oxid. Med. Cell Longev.
, vol.3
, pp. 228-237
-
-
Bouayed, J.1
Bohn, T.2
-
13
-
-
0031200869
-
Free radicals and the pathobiology of brain dopamine systems
-
Cadet J.L., Brannock C. Free radicals and the pathobiology of brain dopamine systems. Neurochem. Int. 1998, 32:117-131.
-
(1998)
Neurochem. Int.
, vol.32
, pp. 117-131
-
-
Cadet, J.L.1
Brannock, C.2
-
14
-
-
64449085359
-
A highly reproducible rotenone model of Parkinson's disease
-
Cannon J.R., Tapias V., Na H.M., Honick A.S., Drolet R.E., Greenamyre J.T. A highly reproducible rotenone model of Parkinson's disease. Neurobiol. Dis. 2009, 34:279-290.
-
(2009)
Neurobiol. Dis.
, vol.34
, pp. 279-290
-
-
Cannon, J.R.1
Tapias, V.2
Na, H.M.3
Honick, A.S.4
Drolet, R.E.5
Greenamyre, J.T.6
-
15
-
-
0037449191
-
Contribution of hydrogen peroxide to the cytotoxicity of green tea and red wines
-
Chai P.C., Long L.H., Halliwell B. Contribution of hydrogen peroxide to the cytotoxicity of green tea and red wines. Biochem. Biophys. Res. Commun. 2003, 304:650-654.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 650-654
-
-
Chai, P.C.1
Long, L.H.2
Halliwell, B.3
-
16
-
-
38449097902
-
Inducible alterations of glutathione levels in adult dopaminergic midbrain neurons result in nigrostriatal degeneration
-
Chinta S.J., Kumar M.J., Hsu M., Rajagopalan S., Kaur D., Rane A., Nicholls D.G., Choi J., Andersen J.K. Inducible alterations of glutathione levels in adult dopaminergic midbrain neurons result in nigrostriatal degeneration. J. Neurosci. 2007, 27:13997-14006.
-
(2007)
J. Neurosci.
, vol.27
, pp. 13997-14006
-
-
Chinta, S.J.1
Kumar, M.J.2
Hsu, M.3
Rajagopalan, S.4
Kaur, D.5
Rane, A.6
Nicholls, D.G.7
Choi, J.8
Andersen, J.K.9
-
17
-
-
78651367197
-
Effects of intrastriatal GDNF on the response of dopamine neurons to 6-hydroxydopamine: time course of protection and neurorestoration
-
Cohen A.D., Zigmond M.J., Smith A.D. Effects of intrastriatal GDNF on the response of dopamine neurons to 6-hydroxydopamine: time course of protection and neurorestoration. Brain Res. 2011, 1370:80-88.
-
(2011)
Brain Res.
, vol.1370
, pp. 80-88
-
-
Cohen, A.D.1
Zigmond, M.J.2
Smith, A.D.3
-
18
-
-
77955123767
-
Melatonin prevents the decreased activity of antioxidant enzymes and activates nuclear erythroid 2-related factor 2 signaling in an animal model of fulminant hepatic failure of viral origin
-
Crespo I., Miguel B.S., Laliena A., Alvarez M., Culebras J.M., Gonzalez-Gallego J., Tunon M.J. Melatonin prevents the decreased activity of antioxidant enzymes and activates nuclear erythroid 2-related factor 2 signaling in an animal model of fulminant hepatic failure of viral origin. J. Pineal Res. 2010, 49:193-200.
-
(2010)
J. Pineal Res.
, vol.49
, pp. 193-200
-
-
Crespo, I.1
Miguel, B.S.2
Laliena, A.3
Alvarez, M.4
Culebras, J.M.5
Gonzalez-Gallego, J.6
Tunon, M.J.7
-
19
-
-
42649144101
-
Oxidative and nitrative protein modifications in Parkinson's disease
-
Danielson S.R., Andersen J.K. Oxidative and nitrative protein modifications in Parkinson's disease. Free Radic. Biol. Med. 2008, 44:1787-1794.
-
(2008)
Free Radic. Biol. Med.
, vol.44
, pp. 1787-1794
-
-
Danielson, S.R.1
Andersen, J.K.2
-
20
-
-
0029873904
-
Threshold effects and control of oxidative phosphorylation in nonsynaptic rat brain mitochondria
-
Davey G.P., Clark J.B. Threshold effects and control of oxidative phosphorylation in nonsynaptic rat brain mitochondria. J. Neurochem. 1996, 66:1617-1624.
-
(1996)
J. Neurochem.
, vol.66
, pp. 1617-1624
-
-
Davey, G.P.1
Clark, J.B.2
-
21
-
-
69249214137
-
Quercetin can act either as an inhibitor or an inducer of the mitochondrial permeability transition pore: A demonstration of the ambivalent redox character of polyphenols
-
De Marchi U., Biasutto L., Garbisa S., Toninello A., Zoratti M. Quercetin can act either as an inhibitor or an inducer of the mitochondrial permeability transition pore: A demonstration of the ambivalent redox character of polyphenols. Biochim. Biophys. Acta. 2009, 1787:1425-1432.
-
(2009)
Biochim. Biophys. Acta.
, vol.1787
, pp. 1425-1432
-
-
De Marchi, U.1
Biasutto, L.2
Garbisa, S.3
Toninello, A.4
Zoratti, M.5
-
22
-
-
0024585155
-
Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease
-
Dexter D.T., Carter C.J., Wells F.R., Javoy-Agid F., Agid Y., Lees A., Jenner P., Marsden C.D. Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease. J. Neurochem. 1989, 52:381-389.
-
(1989)
J. Neurochem.
, vol.52
, pp. 381-389
-
-
Dexter, D.T.1
Carter, C.J.2
Wells, F.R.3
Javoy-Agid, F.4
Agid, Y.5
Lees, A.6
Jenner, P.7
Marsden, C.D.8
-
23
-
-
18144407246
-
Green tea extract and (-)-epigallocatechin-3-gallate, the major tea catechin, exert oxidant but lack antioxidant activities
-
Elbling L., Weiss R.M., Teufelhofer O., Uhl M., Knasmueller S., Schulte-Hermann R., Berger W., Micksche M. Green tea extract and (-)-epigallocatechin-3-gallate, the major tea catechin, exert oxidant but lack antioxidant activities. FASEB J. 2005, 19:807-809.
-
(2005)
FASEB J.
, vol.19
, pp. 807-809
-
-
Elbling, L.1
Weiss, R.M.2
Teufelhofer, O.3
Uhl, M.4
Knasmueller, S.5
Schulte-Hermann, R.6
Berger, W.7
Micksche, M.8
-
24
-
-
0025814980
-
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
-
Esterbauer H., Schaur R.J., Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 1991, 11:81-128.
-
(1991)
Free Radic. Biol. Med.
, vol.11
, pp. 81-128
-
-
Esterbauer, H.1
Schaur, R.J.2
Zollner, H.3
-
25
-
-
2442571064
-
Cytotoxicity, ROS-generation activity and radical-scavenging activity of curcumin and related compounds
-
Fujisawa S., Atsumi T., Ishihara M., Kadoma Y. Cytotoxicity, ROS-generation activity and radical-scavenging activity of curcumin and related compounds. Anticancer Res. 2004, 24:563-569.
-
(2004)
Anticancer Res.
, vol.24
, pp. 563-569
-
-
Fujisawa, S.1
Atsumi, T.2
Ishihara, M.3
Kadoma, Y.4
-
26
-
-
0033852366
-
Assessing antioxidant and prooxidant activities of phenolic compounds
-
Fukumoto L.R., Mazza G. Assessing antioxidant and prooxidant activities of phenolic compounds. J. Agric. Food Chem. 2000, 48:3597-3604.
-
(2000)
J. Agric. Food Chem.
, vol.48
, pp. 3597-3604
-
-
Fukumoto, L.R.1
Mazza, G.2
-
27
-
-
31644435641
-
Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins
-
Galati G., Lin A., Sultan A.M., O'Brien P.J. Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins. Free Radic. Biol. Med. 2006, 40:570-580.
-
(2006)
Free Radic. Biol. Med.
, vol.40
, pp. 570-580
-
-
Galati, G.1
Lin, A.2
Sultan, A.M.3
O'Brien, P.J.4
-
28
-
-
3042574709
-
Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties
-
Galati G., O'Brien P.J. Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties. Free Radic. Biol. Med. 2004, 37:287-303.
-
(2004)
Free Radic. Biol. Med.
, vol.37
, pp. 287-303
-
-
Galati, G.1
O'Brien, P.J.2
-
29
-
-
0037096193
-
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases
-
Giasson B.I., Ischiropoulos H., Lee V.M., Trojanowski J.Q. The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases. Free Radic. Biol. Med. 2002, 32:1264-1275.
-
(2002)
Free Radic. Biol. Med.
, vol.32
, pp. 1264-1275
-
-
Giasson, B.I.1
Ischiropoulos, H.2
Lee, V.M.3
Trojanowski, J.Q.4
-
30
-
-
0033788223
-
Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing
-
Gil M.I., Tomas-Barberan F.A., Hess-Pierce B., Holcroft D.M., Kader A.A. Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J. Agric. Food Chem. 2000, 48:4581-4589.
-
(2000)
J. Agric. Food Chem.
, vol.48
, pp. 4581-4589
-
-
Gil, M.I.1
Tomas-Barberan, F.A.2
Hess-Pierce, B.3
Holcroft, D.M.4
Kader, A.A.5
-
31
-
-
0031939204
-
Protein nitration in Parkinson's disease
-
Good P.F., Hsu A., Werner P., Perl D.P., Olanow C.W. Protein nitration in Parkinson's disease. J. Neuropathol. Exp. Neurol. 1998, 57:338-342.
-
(1998)
J. Neuropathol. Exp. Neurol.
, vol.57
, pp. 338-342
-
-
Good, P.F.1
Hsu, A.2
Werner, P.3
Perl, D.P.4
Olanow, C.W.5
-
32
-
-
34548416749
-
Differential regulation of CD11b on gammadelta T cells and monocytes in response to unripe apple polyphenols
-
Graff J.C., Jutila M.A. Differential regulation of CD11b on gammadelta T cells and monocytes in response to unripe apple polyphenols. J. Leukoc. Biol. 2007, 82:603-607.
-
(2007)
J. Leukoc. Biol.
, vol.82
, pp. 603-607
-
-
Graff, J.C.1
Jutila, M.A.2
-
33
-
-
0036138997
-
Complex I and Parkinson's disease
-
Greenamyre J.T., Sherer T.B., Betarbet R., Panov A.V. Complex I and Parkinson's disease. IUBMB Life 2001, 52:135-141.
-
(2001)
IUBMB Life
, vol.52
, pp. 135-141
-
-
Greenamyre, J.T.1
Sherer, T.B.2
Betarbet, R.3
Panov, A.V.4
-
34
-
-
36549060678
-
Protective effects of green tea polyphenols in the 6-OHDA rat model of Parkinson's disease through inhibition of ROS-NO pathway
-
Guo S., Yan J., Yang T., Yang X., Bezard E., Zhao B. Protective effects of green tea polyphenols in the 6-OHDA rat model of Parkinson's disease through inhibition of ROS-NO pathway. Biol. Psychiatry 2007, 62:1353-1362.
-
(2007)
Biol. Psychiatry
, vol.62
, pp. 1353-1362
-
-
Guo, S.1
Yan, J.2
Yang, T.3
Yang, X.4
Bezard, E.5
Zhao, B.6
-
35
-
-
33750807197
-
Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease
-
Hartman R.E., Shah A., Fagan A.M., Schwetye K.E., Parsadanian M., Schulman R.N., Finn M.B., Holtzman D.M. Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease. Neurobiol. Dis. 2006, 24:506-515.
-
(2006)
Neurobiol. Dis.
, vol.24
, pp. 506-515
-
-
Hartman, R.E.1
Shah, A.2
Fagan, A.M.3
Schwetye, K.E.4
Parsadanian, M.5
Schulman, R.N.6
Finn, M.B.7
Holtzman, D.M.8
-
36
-
-
0141767129
-
Role of nitric oxide in rotenone-induced nigro-striatal injury
-
He Y., Imam S.Z., Dong Z., Jankovic J., Ali S.F., Appel S.H., Le W. Role of nitric oxide in rotenone-induced nigro-striatal injury. J. Neurochem. 2003, 86:1338-1345.
-
(2003)
J. Neurochem.
, vol.86
, pp. 1338-1345
-
-
He, Y.1
Imam, S.Z.2
Dong, Z.3
Jankovic, J.4
Ali, S.F.5
Appel, S.H.6
Le, W.7
-
37
-
-
0031771518
-
Interaction of alpha-phenyl-N-tert-butyl nitrone and alternative electron acceptors with complex I indicates a substrate reduction site upstream from the rotenone binding site
-
Hensley K., Pye Q.N., Maidt M.L., Stewart C.A., Robinson K.A., Jaffrey F., Floyd R.A. Interaction of alpha-phenyl-N-tert-butyl nitrone and alternative electron acceptors with complex I indicates a substrate reduction site upstream from the rotenone binding site. J. Neurochem. 1998, 71:2549-2557.
-
(1998)
J. Neurochem.
, vol.71
, pp. 2549-2557
-
-
Hensley, K.1
Pye, Q.N.2
Maidt, M.L.3
Stewart, C.A.4
Robinson, K.A.5
Jaffrey, F.6
Floyd, R.A.7
-
38
-
-
77953262917
-
Neuroprotective effectsof hydrogen sulfide on Parkinson's disease rat models
-
Hu L.F., Lu M., Tiong C.X., Dawe G.S., Hu G., Bian J.S. Neuroprotective effectsof hydrogen sulfide on Parkinson's disease rat models. Aging Cell 2010, 9:135-146.
-
(2010)
Aging Cell
, vol.9
, pp. 135-146
-
-
Hu, L.F.1
Lu, M.2
Tiong, C.X.3
Dawe, G.S.4
Hu, G.5
Bian, J.S.6
-
39
-
-
0030842085
-
Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease
-
Hunot S., Brugg B., Ricard D., Michel P.P., Muriel M.P., Ruberg M., Faucheux B.A., Agid Y., Hirsch E.C. Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease. Proc. Natl. Acad. Sci. U. S. A 1997, 94:7531-7536.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A
, vol.94
, pp. 7531-7536
-
-
Hunot, S.1
Brugg, B.2
Ricard, D.3
Michel, P.P.4
Muriel, M.P.5
Ruberg, M.6
Faucheux, B.A.7
Agid, Y.8
Hirsch, E.C.9
-
40
-
-
0037378026
-
Oxidative stress in Parkinson's disease
-
discussion S36-8
-
Jenner P. Oxidative stress in Parkinson's disease. Ann. Neurol. 2003, 53(Suppl 3):S26-S36. discussion S36-8.
-
(2003)
Ann. Neurol.
, vol.53
, Issue.SUPPL 3
-
-
Jenner, P.1
-
41
-
-
0034520395
-
Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenases-1 and -2
-
Knott C., Stern G., Wilkin G.P. Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenases-1 and -2. Mol. Cell Neurosci. 2000, 16:724-739.
-
(2000)
Mol. Cell Neurosci.
, vol.16
, pp. 724-739
-
-
Knott, C.1
Stern, G.2
Wilkin, G.P.3
-
42
-
-
74649084016
-
Pomegranate extract induces apoptosis in human prostate cancer cells by modulation of the IGF-IGFBP axis
-
Koyama S., Cobb L.J., Mehta H.H., Seeram N.P., Heber D., Pantuck A.J., Cohen P. Pomegranate extract induces apoptosis in human prostate cancer cells by modulation of the IGF-IGFBP axis. Growth Horm. IGF Res. 2010, 20:55-62.
-
(2010)
Growth Horm. IGF Res.
, vol.20
, pp. 55-62
-
-
Koyama, S.1
Cobb, L.J.2
Mehta, H.H.3
Seeram, N.P.4
Heber, D.5
Pantuck, A.J.6
Cohen, P.7
-
43
-
-
72149118194
-
Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice
-
Lambert J.D., Kennett M.J., Sang S., Reuhl K.R., Ju J., Yang C.S. Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice. Food Chem. Toxicol. 2010, 48:409-416.
-
(2010)
Food Chem. Toxicol.
, vol.48
, pp. 409-416
-
-
Lambert, J.D.1
Kennett, M.J.2
Sang, S.3
Reuhl, K.R.4
Ju, J.5
Yang, C.S.6
-
44
-
-
0036145435
-
Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-kappaB) activation and cell death by tea extracts in neuronal cultures
-
Levites Y., Youdim M.B., Maor G., Mandel S. Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-kappaB) activation and cell death by tea extracts in neuronal cultures. Biochem. Pharmacol. 2002, 63:21-29.
-
(2002)
Biochem. Pharmacol.
, vol.63
, pp. 21-29
-
-
Levites, Y.1
Youdim, M.B.2
Maor, G.3
Mandel, S.4
-
45
-
-
34247359586
-
An orally active catalytic metalloporphyrin protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in vivo
-
Liang L.P., Huang J., Fulton R., Day B.J., Patel M. An orally active catalytic metalloporphyrin protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in vivo. J. Neurosci. 2007, 27:4326-4333.
-
(2007)
J. Neurosci.
, vol.27
, pp. 4326-4333
-
-
Liang, L.P.1
Huang, J.2
Fulton, R.3
Day, B.J.4
Patel, M.5
-
46
-
-
0032710609
-
Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease
-
Liberatore G.T., Jackson-Lewis V., Vukosavic S., Mandir A.S., Vila M., McAuliffe W.G., Dawson V.L., Dawson T.M., Przedborski S. Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease. Nat. Med. 1999, 5:1403-1409.
-
(1999)
Nat. Med.
, vol.5
, pp. 1403-1409
-
-
Liberatore, G.T.1
Jackson-Lewis, V.2
Vukosavic, S.3
Mandir, A.S.4
Vila, M.5
McAuliffe, W.G.6
Dawson, V.L.7
Dawson, T.M.8
Przedborski, S.9
-
47
-
-
78650525484
-
ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease
-
Maher P., Dargusch R., Bodai L., Gerard P.E., Purcell J.M., Marsh J.L. ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease. Hum. Mol. Genet. 2011, 20:261-270.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 261-270
-
-
Maher, P.1
Dargusch, R.2
Bodai, L.3
Gerard, P.E.4
Purcell, J.M.5
Marsh, J.L.6
-
48
-
-
0023789193
-
Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
-
McGeer P.L., Itagaki S., Boyes B.E., McGeer E.G. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 1988, 38:1285-1291.
-
(1988)
Neurology
, vol.38
, pp. 1285-1291
-
-
McGeer, P.L.1
Itagaki, S.2
Boyes, B.E.3
McGeer, E.G.4
-
49
-
-
0345148810
-
Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal product
-
Metodiewa D., Jaiswal A.K., Cenas N., Dickancaite E., Segura-Aguilar J. Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal product. Free Radic. Biol. Med. 1999, 26:107-116.
-
(1999)
Free Radic. Biol. Med.
, vol.26
, pp. 107-116
-
-
Metodiewa, D.1
Jaiswal, A.K.2
Cenas, N.3
Dickancaite, E.4
Segura-Aguilar, J.5
-
50
-
-
0030582991
-
Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease
-
Mogi M., Harada M., Narabayashi H., Inagaki H., Minami M., Nagatsu T. Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease. Neurosci. Lett. 1996, 211:13-16.
-
(1996)
Neurosci. Lett.
, vol.211
, pp. 13-16
-
-
Mogi, M.1
Harada, M.2
Narabayashi, H.3
Inagaki, H.4
Minami, M.5
Nagatsu, T.6
-
51
-
-
4544236944
-
Generation of hydrogen peroxide primarily contributes to the induction of Fe(II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate
-
Nakagawa H., Hasumi K., Woo J.T., Nagai K., Wachi M. Generation of hydrogen peroxide primarily contributes to the induction of Fe(II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate. Carcinogenesis 2004, 25:1567-1574.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1567-1574
-
-
Nakagawa, H.1
Hasumi, K.2
Woo, J.T.3
Nagai, K.4
Wachi, M.5
-
52
-
-
0042195863
-
Catechins induce oxidative damage to cellular and isolated DNA through the generation of reactive oxygen species
-
Oikawa S., Furukawaa A., Asada H., Hirakawa K., Kawanishi S. Catechins induce oxidative damage to cellular and isolated DNA through the generation of reactive oxygen species. Free Radic. Res. 2003, 37:881-890.
-
(2003)
Free Radic. Res.
, vol.37
, pp. 881-890
-
-
Oikawa, S.1
Furukawaa, A.2
Asada, H.3
Hirakawa, K.4
Kawanishi, S.5
-
53
-
-
33747286388
-
Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets
-
Ramassamy C. Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets. Eur. J. Pharmacol. 2006, 545:51-64.
-
(2006)
Eur. J. Pharmacol.
, vol.545
, pp. 51-64
-
-
Ramassamy, C.1
-
54
-
-
23944513613
-
Green tea polyphenol epigallocatechin-3-gallate differentially modulates oxidative stress in PC12 cell compartments
-
Raza H., John A. Green tea polyphenol epigallocatechin-3-gallate differentially modulates oxidative stress in PC12 cell compartments. Toxicol. Appl. Pharmacol. 2005, 207:212-220.
-
(2005)
Toxicol. Appl. Pharmacol.
, vol.207
, pp. 212-220
-
-
Raza, H.1
John, A.2
-
55
-
-
0028293038
-
Time course of recovery of extracellular dopamine following partial damage to the nigrostriatal dopamine system
-
Robinson T.E., Mocsary Z., Camp D.M., Whishaw I.Q. Time course of recovery of extracellular dopamine following partial damage to the nigrostriatal dopamine system. J. Neurosci. 1994, 14:2687-2696.
-
(1994)
J. Neurosci.
, vol.14
, pp. 2687-2696
-
-
Robinson, T.E.1
Mocsary, Z.2
Camp, D.M.3
Whishaw, I.Q.4
-
56
-
-
77951546947
-
The major green tea polyphenol, (-)-epigallocatechin-3-gallate, induces heme oxygenase in rat neurons and acts as an effective neuroprotective agent against oxidative stress
-
Romeo L., Intrieri M., D'Agata V., Mangano N.G., Oriani G., Ontario M.L., Scapagnini G. The major green tea polyphenol, (-)-epigallocatechin-3-gallate, induces heme oxygenase in rat neurons and acts as an effective neuroprotective agent against oxidative stress. J. Am. Coll. Nutr. 2009, 28(Suppl):492S-499S.
-
(2009)
J. Am. Coll. Nutr.
, vol.28
, Issue.SUPPL
-
-
Romeo, L.1
Intrieri, M.2
D'Agata, V.3
Mangano, N.G.4
Oriani, G.5
Ontario, M.L.6
Scapagnini, G.7
-
57
-
-
32944475325
-
Synthesis and structure identification of thiol conjugates of (-)-epigallocatechin gallate and their urinary levels in mice
-
Sang S., Lambert J.D., Hong J., Tian S., Lee M.J., Stark R.E., Ho C.T., Yang C.S. Synthesis and structure identification of thiol conjugates of (-)-epigallocatechin gallate and their urinary levels in mice. Chem. Res. Toxicol. 2005, 18:1762-1769.
-
(2005)
Chem. Res. Toxicol.
, vol.18
, pp. 1762-1769
-
-
Sang, S.1
Lambert, J.D.2
Hong, J.3
Tian, S.4
Lee, M.J.5
Stark, R.E.6
Ho, C.T.7
Yang, C.S.8
-
58
-
-
0000431473
-
Intervention strategies for degeneration of dopamine neurons in parkinsonism: optimizing behavioral assessment of outcome
-
Humana Press, Totowa, New Jersey, United States, R.L. Dean, D.F. Emerich, P.R. Sanberg (Eds.)
-
Schallert T., Tillerson J.L. Intervention strategies for degeneration of dopamine neurons in parkinsonism: optimizing behavioral assessment of outcome. Central Nervous System Diseases: Innovative models of CNS diseases from molecule to therapy 2000, 131-151. Humana Press, Totowa, New Jersey, United States. R.L. Dean, D.F. Emerich, P.R. Sanberg (Eds.).
-
(2000)
Central Nervous System Diseases: Innovative models of CNS diseases from molecule to therapy
, pp. 131-151
-
-
Schallert, T.1
Tillerson, J.L.2
-
59
-
-
0024390719
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira A.H., Cooper J.M., Dexter D., Jenner P., Clark J.B., Marsden C.D. Mitochondrial complex I deficiency in Parkinson's disease. Lancet 1989, 1:1269.
-
(1989)
Lancet
, vol.1
, pp. 1269
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Jenner, P.4
Clark, J.B.5
Marsden, C.D.6
-
60
-
-
0037402801
-
Selective microglial activation in the rat rotenone model of Parkinson's disease
-
Sherer T.B., Betarbet R., Kim J.H., Greenamyre J.T. Selective microglial activation in the rat rotenone model of Parkinson's disease. Neurosci. Lett. 2003, 341:87-90.
-
(2003)
Neurosci. Lett.
, vol.341
, pp. 87-90
-
-
Sherer, T.B.1
Betarbet, R.2
Kim, J.H.3
Greenamyre, J.T.4
-
61
-
-
0344198025
-
Mechanism of toxicity in rotenone models of Parkinson's disease
-
Sherer T.B., Betarbet R., Testa C.M., Seo B.B., Richardson J.R., Kim J.H., Miller G.W., Yagi T., Matsuno-Yagi A., Greenamyre J.T. Mechanism of toxicity in rotenone models of Parkinson's disease. J. Neurosci. 2003, 23:10756-10764.
-
(2003)
J. Neurosci.
, vol.23
, pp. 10756-10764
-
-
Sherer, T.B.1
Betarbet, R.2
Testa, C.M.3
Seo, B.B.4
Richardson, J.R.5
Kim, J.H.6
Miller, G.W.7
Yagi, T.8
Matsuno-Yagi, A.9
Greenamyre, J.T.10
-
62
-
-
0028075410
-
Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
-
Sian J., Dexter D.T., Lees A.J., Daniel S., Agid Y., Javoy-Agid F., Jenner P., Marsden C.D. Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann. Neurol. 1994, 36:348-355.
-
(1994)
Ann. Neurol.
, vol.36
, pp. 348-355
-
-
Sian, J.1
Dexter, D.T.2
Lees, A.J.3
Daniel, S.4
Agid, Y.5
Javoy-Agid, F.6
Jenner, P.7
Marsden, C.D.8
-
63
-
-
74049134972
-
Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model
-
Tapias V., Cannon J.R., Greenamyre J.T. Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model. J. Neurosci. Res. 2010, 88:420-427.
-
(2010)
J. Neurosci. Res.
, vol.88
, pp. 420-427
-
-
Tapias, V.1
Cannon, J.R.2
Greenamyre, J.T.3
-
64
-
-
68249127673
-
Melatonin and its brainmetabolite N(1)-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice
-
Tapias V., Escames G., Lopez L.C., Lopez A., Camacho E., Carrion M.D., Entrena A., Gallo M.A., Espinosa A., Acuna-Castroviejo D. Melatonin and its brainmetabolite N(1)-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice. J. Neurosci. Res 2009, 87:3002-3010.
-
(2009)
J. Neurosci. Res
, vol.87
, pp. 3002-3010
-
-
Tapias, V.1
Escames, G.2
Lopez, L.C.3
Lopez, A.4
Camacho, E.5
Carrion, M.D.6
Entrena, A.7
Gallo, M.A.8
Espinosa, A.9
Acuna-Castroviejo, D.10
-
65
-
-
84876338056
-
Automated imaging system for fast quantitation of neurons, cell morphology and neurite morphometry in vivo and in vitro
-
Tapias V., Greenamyre J.T., Watkins S.C. Automated imaging system for fast quantitation of neurons, cell morphology and neurite morphometry in vivo and in vitro. Neurobiol. Dis. 2013, 54:158-168.
-
(2013)
Neurobiol. Dis.
, vol.54
, pp. 158-168
-
-
Tapias, V.1
Greenamyre, J.T.2
Watkins, S.C.3
-
66
-
-
0038641723
-
Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration
-
Teismann P., Tieu K., Choi D.K., Wu D.C., Naini A., Hunot S., Vila M., Jackson-Lewis V., Przedborski S. Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration. Proc. Natl. Acad. Sci. U. S. A 2003, 100:5473-5478.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A
, vol.100
, pp. 5473-5478
-
-
Teismann, P.1
Tieu, K.2
Choi, D.K.3
Wu, D.C.4
Naini, A.5
Hunot, S.6
Vila, M.7
Jackson-Lewis, V.8
Przedborski, S.9
-
67
-
-
0034284635
-
Dopamine transporter function assessed by antisense knockdown in the rat: protection from dopamine neurotoxicity
-
Van Kampen J.M., McGeer E.G., Stoessl A.J. Dopamine transporter function assessed by antisense knockdown in the rat: protection from dopamine neurotoxicity. Synapse 2000, 37:171-178.
-
(2000)
Synapse
, vol.37
, pp. 171-178
-
-
Van Kampen, J.M.1
McGeer, E.G.2
Stoessl, A.J.3
-
68
-
-
4644313472
-
Gene expression changes induced by green tea polyphenol (-)-epigallocatechin-3-gallate in human bronchial epithelial 21BES cells analyzed by DNA microarray
-
Vittal R., Selvanayagam Z.E., Sun Y., Hong J., Liu F., Chin K.V., Yang C.S. Gene expression changes induced by green tea polyphenol (-)-epigallocatechin-3-gallate in human bronchial epithelial 21BES cells analyzed by DNA microarray. Mol. Cancer Ther. 2004, 3:1091-1099.
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 1091-1099
-
-
Vittal, R.1
Selvanayagam, Z.E.2
Sun, Y.3
Hong, J.4
Liu, F.5
Chin, K.V.6
Yang, C.S.7
-
69
-
-
14944364739
-
Low concentrations of flavonoids are protective in rat H4IIE cells whereas high concentrations cause DNA damage and apoptosis
-
Watjen W., Michels G., Steffan B., Niering P., Chovolou Y., Kampkotter A., Tran-Thi Q.H., Proksch P., Kahl R. Low concentrations of flavonoids are protective in rat H4IIE cells whereas high concentrations cause DNA damage and apoptosis. J. Nutr. 2005, 135:525-531.
-
(2005)
J. Nutr.
, vol.135
, pp. 525-531
-
-
Watjen, W.1
Michels, G.2
Steffan, B.3
Niering, P.4
Chovolou, Y.5
Kampkotter, A.6
Tran-Thi, Q.H.7
Proksch, P.8
Kahl, R.9
-
70
-
-
43449119803
-
Enhanced function in the good forelimb of hemi-parkinson rats: compensatory adaptation for contralateral postural instability?
-
Woodlee M.T., Kane J.R., Chang J., Cormack L.K., Schallert T. Enhanced function in the good forelimb of hemi-parkinson rats: compensatory adaptation for contralateral postural instability?. Exp. Neurol. 2008, 211:511-517.
-
(2008)
Exp. Neurol.
, vol.211
, pp. 511-517
-
-
Woodlee, M.T.1
Kane, J.R.2
Chang, J.3
Cormack, L.K.4
Schallert, T.5
-
71
-
-
0036522967
-
Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
-
Wu D.C., Jackson-Lewis V., Vila M., Tieu K., Teismann P., Vadseth C., Choi D.K., Ischiropoulos H., Przedborski S. Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J. Neurosci. 2002, 22:1763-1771.
-
(2002)
J. Neurosci.
, vol.22
, pp. 1763-1771
-
-
Wu, D.C.1
Jackson-Lewis, V.2
Vila, M.3
Tieu, K.4
Teismann, P.5
Vadseth, C.6
Choi, D.K.7
Ischiropoulos, H.8
Przedborski, S.9
-
72
-
-
68949173926
-
Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation
-
Wu H.M., Tzeng N.S., Qian L., Wei S.J., Hu X., Chen S.H., Rawls S.M., Flood P., Hong J.S., Lu R.B. Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation. Neuropsychopharmacology 2009, 34:2344-2357.
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 2344-2357
-
-
Wu, H.M.1
Tzeng, N.S.2
Qian, L.3
Wei, S.J.4
Hu, X.5
Chen, S.H.6
Rawls, S.M.7
Flood, P.8
Hong, J.S.9
Lu, R.B.10
-
73
-
-
20344363680
-
Systematic administration of iptakalim, an ATP-sensitive potassium channel opener, prevents rotenone-induced motor and neurochemical alterations in rats
-
Yang Y., Liu X., Long Y., Wang F., Ding J.H., Liu S.Y., Sun Y.H., Yao H.H., Wang H., Wu J., Hu G. Systematic administration of iptakalim, an ATP-sensitive potassium channel opener, prevents rotenone-induced motor and neurochemical alterations in rats. J. Neurosci. Res. 2005, 80:442-449.
-
(2005)
J. Neurosci. Res.
, vol.80
, pp. 442-449
-
-
Yang, Y.1
Liu, X.2
Long, Y.3
Wang, F.4
Ding, J.H.5
Liu, S.Y.6
Sun, Y.H.7
Yao, H.H.8
Wang, H.9
Wu, J.10
Hu, G.11
-
74
-
-
0842302388
-
Modulation of tea and tea polyphenols on benzo(a)pyrene-induced DNA damage in Chang liver cells
-
Yen G.C., Ju J.W., Wu C.H. Modulation of tea and tea polyphenols on benzo(a)pyrene-induced DNA damage in Chang liver cells. Free Radic. Res. 2004, 38:193-200.
-
(2004)
Free Radic. Res.
, vol.38
, pp. 193-200
-
-
Yen, G.C.1
Ju, J.W.2
Wu, C.H.3
-
75
-
-
0029917194
-
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease
-
Yoritaka A., Hattori N., Uchida K., Tanaka M., Stadtman E.R., Mizuno Y. Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease. Proc. Natl. Acad. Sci. U. S. A 1996, 93:2696-2701.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A
, vol.93
, pp. 2696-2701
-
-
Yoritaka, A.1
Hattori, N.2
Uchida, K.3
Tanaka, M.4
Stadtman, E.R.5
Mizuno, Y.6
-
76
-
-
77949532182
-
Curcumin prevents dopaminergic neuronal death through inhibition of the c-Jun N-terminal kinase pathway
-
Yu S., Zheng W., Xin N., Chi Z.H., Wang N.Q., Nie Y.X., Feng W.Y., Wang Z.Y. Curcumin prevents dopaminergic neuronal death through inhibition of the c-Jun N-terminal kinase pathway. Rejuvenation Res. 2010, 13:55-64.
-
(2010)
Rejuvenation Res.
, vol.13
, pp. 55-64
-
-
Yu, S.1
Zheng, W.2
Xin, N.3
Chi, Z.H.4
Wang, N.Q.5
Nie, Y.X.6
Feng, W.Y.7
Wang, Z.Y.8
-
77
-
-
25444508963
-
Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease
-
Zbarsky V., Datla K.P., Parkar S., Rai D.K., Aruoma O.I., Dexter D.T. Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease. Free Radic. Res. 2005, 39:1119-1125.
-
(2005)
Free Radic. Res.
, vol.39
, pp. 1119-1125
-
-
Zbarsky, V.1
Datla, K.P.2
Parkar, S.3
Rai, D.K.4
Aruoma, O.I.5
Dexter, D.T.6
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