Gene expression changes induced by green tea polyphenol (-)-epigallocatechin-3-gallate in human bronchial epithelial 21BES cells analyzed by DNA microarray

Molecular Cancer Therapeutics

Volumn 3, Issue 9, 2004, Pages 1091-1099

  Vittal, Ragini ^a   Selvanayagam, Zachariah E ^b   Sun, Yi ^a   Hong, Jungil ^a   Liu, Fang ^a,b   Chin, Khew Voon ^a   Yang, Chung S ^a  

^a RUTGERS UNIVERSITY   (United States)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BONE MORPHOGENETIC PROTEIN; CATALASE; CYCLOPHILIN; EPIGALLOCATECHIN GALLATE; HOMEODOMAIN PROTEIN; HYDROGEN PEROXIDE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYPHENOL DERIVATIVE; RAS PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BRONCHUS MUCOSA; CELL METABOLISM; CELL TRANSFORMATION; CONTROLLED STUDY; DNA MICROARRAY; DRUG CYTOTOXICITY; DRUG MECHANISM; GENE EXPRESSION; HUMAN; HUMAN CELL; ONCOGENE H RAS; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; SIGNAL TRANSDUCTION; TEA; TRANSACTIVATION;

ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BRONCHI; CATALASE; CATECHIN; CELL LINE, TRANSFORMED; EPITHELIAL CELLS; ESCHERICHIA COLI PROTEINS; FLAVONOIDS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENES, RAS; HOMEODOMAIN PROTEINS; HUMANS; HYDROGEN PEROXIDE; MIXED FUNCTION OXYGENASES; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDYLPROLYL ISOMERASE; PHENOLS; TEA; TRANSCRIPTION FACTORS;

EID: 4644313472     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Yang CS, Maliakal P, Meng X. Inhibition of carcinogenesis by tea. Annu Rev Pharmacol Toxicol 2002;42:25-54.
2. Yang CS, Wang ZY. Tea and cancer. J Natl Cancer Inst 1993;85: 1038-49.
3. Kohlmeier L, Weterings KG, Steck S, Kok FJ. Tea and cancer prevention: an evaluation of the epidemiologic literature. Nutr Cancer 1997;27: 1-13.
4. Paschka AG, Butler R, Young CY. Induction of apoptosis in prostate cancer cell lines by the green tea component, (-)-epigallocatechin-3-gallate. Cancer Lett 1998;130:1-7.
5. Ahn WS, Huh SW, Bae SM, et al. A major constituent of green tea, EGCG, inhibits the growth of a human cervical cancer cell line, CaSki cells, through apoptosis, G(1) arrest, and regulation of gene expression DNA. Cell Biol 2003;22:217-24.
6. Isemura M, Saeki K, Kimura T, Hayakawa S, Minami T, Sazuka M. Tea catechins and related polyphenols as anti-cancer agents. BioFactors 2000; 13:81-5.
7. Liu JD, Chen SH, Lin CL, Tsai SH, Liang YC. Inhibition of melanoma growth and metastasis by combination with (-)-epigallocatechin-3-gallate and dacarbazine in mice. J Cell Biochem 2001;83:631-42.
8. Masuda M, Suzui M, Weinstein IB. Effects of epigallocatechin-3-gallate on growth, epidermal growth factor receptor signaling pathways, gene expression, and chemosensitivity in human head and neck squamous cell carcinoma cell lines. Clin Cancer Res 2001;7:4220-9.
9. Masuda M, Suzui M, Lim JT, Weinstein IB. Epigallocatechin-3-gallate inhibits activation of HER-2/neu and downstream signaling pathways in human head and neck and breast carcinoma cells. Clin Cancer Res 2003; 9:3486-91.
10. Stammler G, Volm M. Green tea catechins (EGCG and EGC) have modulating effects on the activity of doxorubicin in drug-resistant cell lines. Anticancer Drugs 1997;8:265-8.
11. Naasani I, Seimiya H, Tsuruo T. Telomerase inhibition, telomere shortening, and senescence of cancer cells by tea catechins. Biochem Biophys Res Commun 1998;249:391-6.
12. Naasani I, Oh-Hashi F, Oh-Hara T, et al. Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo. Cancer Res 2003;63:824-30.
13. Chung JY, Huang C, Meng X, Dong Z, Yang CS. Inhibition of activator protein 1 activity and cell growth by purified green tea and black tea polyphenols in H-ras-transformed cells: structure-activity relationship and mechanisms involved. Cancer Res 1999;59:4610-7.
14. Chung JY, Park JO, Phyu H, Dong Z, Yang CS. Mechanisms of inhibition of the Ras-MAP kinase signaling pathway in 30.7b Ras 12 cells by tea polyphenols (-)-epigallocatechin-3-gallate and theaflavin-3,3′-digallate. FASEB J 2001;15:2022-4.
15. Lin JK, Liang YC, Lin-Shiau SY. Cancer chemoprevention by tea polyphenols through mitotic signal transduction blockade. Biochem Pharmacol 1999;58:911-5.
16. Liang YC, Chen YC, Lin YL, Lin-Shiau SY, Ho CT, Lin JK. Suppression of extracellular signals and cell proliferation by the black tea polyphenol, theaflavin-3,3′-digallate. Carcinogenesis 1999;20:733-6.
17. Cao Y, Cao R. Angiogenesis inhibited by drinking tea. Nature 1999; 398:381.
18. Islam S, Islam N, Kermode T, et al. Involvement of caspase-3 in epigallocatechin-3-gallate-mediated apoptosis of human chondrosarcoma cells. Biochem Biophys Res Commun 2000;270:793-7.
19. Yang GY, Liao J, Kim K, Yurkow EJ, Yang CS. Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols. Carcinogenesis 1998;19:611-6.
20. Yang GY, Liao J, Li C, et al. Effect of black and green tea polyphenols on c-jun phosphorylation and H(2)O(2) production in transformed and non-transformed human bronchial cell lines: possible mechanisms of cell growth inhibition and apoptosis induction. Carcinogenesis 2000;21: 2035-9.
21. Hong J, Lu H, Meng X, Ryu JH, Hara Y, Yang CS. Stability, cellular uptake, biotransformation, and efflux of tea polyphenol (-)-epigallocate-chin-3-gallate in HT-29 human colon adenocarcinoma cells. Cancer Res 2002;62:7241-6.
22. Long LH, Clement MV, Halliwell B. Artifacts in cell culture: rapid generation of hydrogen peroxide on addition of (-)-epigallocatechin, (-)-epigallocatechin gallate, (+)-catechin, and quercetin to commonly used cell culture media. Biochem Biophys Res Commun 2000;273:50-3.
23. Dashwood WM, Orner GA, Dashwood RH. Inhibition of β-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations. Biochem Biophys Res Commun 2002;296:584-8.
24. Chin KV, Kong AN. Application of DNA microarrays in pharmacogenomics and toxicogenomics. Pharm Res 2002;19:1773-8.
25. Scherf U, Ross DT, Waltham M, et al. A gene expression database for the molecular pharmacology of cancer. Nat Genet 2000;24:236-44.
26. Zheng X, Ravatn R, Lin Y, et al. Gene expression of TPA induced differentiation in HL-60 cells by DNA microarray analysis. Nucleic Acids Res 2002;30:4489-99.
27. Ogawa N, DeRisi J, Brown PO. New components of a system for phosphate accumulation and polyphosphate metabolism in Saccharomyces cerevisiae revealed by genomic expression analysis. Mol Biol Cell 2000;11:4309-21.
28. Sudarsanam P, Iyer VR, Brown PO, Winston F. Whole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 2000;97:3364-9.
29. Iyer VR, Eisen MB, Ross DT, et al. The transcriptional program in the response of human fibroblasts to serum. Science 1999;283:83-7.
30. Spellman PT, Sherlock G, Zhang MQ, et al. Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Mol Biol Cell 1998;9:3273-97.
31. Weinreb O, Mandel S, Youdim ME. cDNA gene expression profile homology of antioxidants and their antiapoptotic and proapoptotic activities in human neuroblastoma cells. FASEB J 2003;17:935-7.
32. Wang SI, Mukhtar H. Gene expression profile in human prostate LNCaP cancer cells by (-)epigallocatechin-3-gallate. Cancer Lett 2002; 182:43-51.
33. Eisen MB, Spellman PT, Brown PO, Botstein D. Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci U S A 1998;95:14863-8.
34. Long J, Matsuura I, He D, Wang G, Shuai K, Liu F. Repression of Smad transcriptional activity by PIASy, an inhibitor of activated STAT. Proc Natl Acad Sci U S A 2003;100:9791-6.
35. Kusanagi K, Inoue H, Ishidou Y, Mishima HK, Kawabata M, Miyazono K. Characterization of a bone morphogenetic protein-responsive Smad-binding element. Mol Biol Cell 2000;11:555-65.
36. Yamamoto T, Lewis J, Wataha J, et al. Roles of catalase and hydrogen peroxide in green tea polyphenol-induced chemopreventive effects. J Pharmacol Exp Ther 2004;308:317-23.
37. Chuang YY, Chen Y, Gadisetti, et al. Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells. Cancer Res 2002;62:6246-54.
38. Griendling KK, Sorescu D, Lassegue B, Ushio-Fulkai M. Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler Thromb Vasc Biol 2000;20:2175-83.
39. Halliwell B, Clement MV, Ramalingam J, Long LH. Hydrogen peroxide. Ubiquitous in cell culture and in vivo? IUBMB Life 2000;50: 251-7.
40. Shi Y, Massague J. Mechanisms of TGF-β signaling from cell membrane to the nucleus. Cell 2003;113:685-700.
41. Zhao GQ. Consequences of knocking out BMP signaling in the mouse. Genesis 2003;35:43-56.
42. Chong H, Vikis HG, Guan KL. Mechanisms of regulating the Raf kinase family. Cell Signal 2003;15:463-9.
43. Lou J, Tu Y, Li S, Manske PR. Involvement of ERK in BMP-2 induced osteoblastic differentiation of mesenchymal progenitor cell line C3H10T1/2. Biochem Biophys Res Commun 2000;268:757-62.
44. Meerson F, Pozharov V, Minyailenko T. Superresistance against hypoxia after preliminary adaptation to repeated stress. J Appl Physiol 1994;76:1856-61.
45. Lee MJ, Lambert JD, Prabhu S, et al. Delivery of tea polyphenols to the oral cavity by green tea leaves and black tea extract. Cancer Epidemiol Biomarkers Prev 2004;13:132-7.