메뉴 건너뛰기




Volumn 723, Issue 1, 2014, Pages 473-480

Inhibitory effects of obovatol on osteoclast differentiation and bone resorption

Author keywords

Apoptosis; Bone resorption; Cytoskeletal organization; Obovatol; Osteoclast; RANKL

Indexed keywords

APOPTOSIS; BONE RESORPTION; CYTOSKELETAL ORGANIZATION; OBOVATOL; OSTEOCLAST; RANKL;

EID: 84893756178     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.10.027     Document Type: Article
Times cited : (8)

References (43)
  • 2
    • 33846031926 scopus 로고    scopus 로고
    • The molecular understanding of osteoclast differentiation
    • DOI 10.1016/j.bone.2006.09.023, PII S8756328206007009
    • M. Asagiri, and H. Takayanagi The molecular understanding of osteoclast differentiation Bone 40 2007 251 264 (Pubitemid 46054562)
    • (2007) Bone , vol.40 , Issue.2 , pp. 251-264
    • Asagiri, M.1    Takayanagi, H.2
  • 3
    • 84856783815 scopus 로고    scopus 로고
    • Update on bone anabolics in osteoporosis treatment: Rationale, current status, and perspectives
    • R. Baron, and E. Hesse Update on bone anabolics in osteoporosis treatment: rationale, current status, and perspectives J. Clin. Endocrinol. Metab. 97 2012 311 325
    • (2012) J. Clin. Endocrinol. Metab. , vol.97 , pp. 311-325
    • Baron, R.1    Hesse, E.2
  • 5
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • DOI 10.1038/nature01658
    • W.J. Boyle, W.S. Simonet, and D.L. Lacey Osteoclast differentiation and activation Nature 423 2003 337 342 (Pubitemid 40852708)
    • (2003) Nature , vol.423 , Issue.6937 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 6
    • 33845984343 scopus 로고    scopus 로고
    • Molecular regulation of osteoclast activity
    • DOI 10.1007/s11154-006-9009-x, Special Issue on Osteoporosis
    • A. Bruzzaniti, and R. Baron Molecular regulation of osteoclast activity Rev. Endocr. Metab. Disord. 7 2006 123 139 (Pubitemid 46044352)
    • (2006) Reviews in Endocrine and Metabolic Disorders , vol.7 , Issue.1-2 , pp. 123-139
    • Bruzzaniti, A.1    Baron, R.2
  • 7
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • DOI 10.1038/35065000
    • L. Chang, and M. Karin Mammalian MAP kinase signalling cascades Nature 410 2001 37 40 (Pubitemid 32225829)
    • (2001) Nature , vol.410 , Issue.6824 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 10
    • 33846260180 scopus 로고    scopus 로고
    • Inhibitory effect of obovatol on nitric oxide production and activation of NF-κB/MAP kinases in lipopolysaccharide-treated RAW 264.7cells
    • DOI 10.1016/j.ejphar.2006.10.054, PII S001429990601185X
    • M.S. Choi, S.H. Lee, H.S. Cho, Y. Kim, Y.P. Yun, H.Y. Jung, J.K. Jung, B.C. Lee, H.B. Pyo, and J.T. Hong Inhibitory effect of obovatol on nitric oxide production and activation of NF-kappaB/MAP kinases in lipopolysaccharide-treated RAW 264.7cells Eur. J. Pharmacol. 556 2007 181 189 (Pubitemid 46098933)
    • (2007) European Journal of Pharmacology , vol.556 , Issue.1-3 , pp. 181-189
    • Choi, M.S.1    Lee, S.H.2    Cho, H.S.3    Kim, Y.4    Yun, Y.P.5    Jung, H.Y.6    Jung, J.K.7    Lee, B.C.8    Pyo, H.B.9    Hong, J.T.10
  • 14
    • 1842690120 scopus 로고    scopus 로고
    • The Calcineurin/Nuclear Factor of Activated T Cells Signaling Pathway Regulates Osteoclastogenesis in RAW264.7 Cells
    • DOI 10.1074/jbc.M213067200
    • H. Hirotani, N.A. Tuohy, J.T. Woo, P.H. Stern, and N.A. Clipstone The calcineurin/nuclear factor of activated T cells signaling pathway regulates osteoclastogenesis in RAW264.7 cells J. Biol. Chem. 279 2004 13984 13992 (Pubitemid 38468932)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.14 , pp. 13984-13992
    • Hirotani, H.1    Tuohy, N.A.2    Woo, J.-T.3    Stern, P.H.4    Clipstone, N.A.5
  • 15
    • 79951822972 scopus 로고    scopus 로고
    • Calpain-6, a target molecule of glucocorticoids, regulates osteoclastic bone resorption via cytoskeletal organization and microtubule acetylation
    • J.M. Hong, S.L. Teitelbaum, T.H. Kim, F.P. Ross, S.Y. Kim, and H.J. Kim Calpain-6, a target molecule of glucocorticoids, regulates osteoclastic bone resorption via cytoskeletal organization and microtubule acetylation J. Bone Miner. Res. 26 2011 657 665
    • (2011) J. Bone Miner. Res. , vol.26 , pp. 657-665
    • Hong, J.M.1    Teitelbaum, S.L.2    Kim, T.H.3    Ross, F.P.4    Kim, S.Y.5    Kim, H.J.6
  • 17
    • 0037135568 scopus 로고    scopus 로고
    • Transforming growth factor-β induces expression of receptor activator of NF-κB ligand in vascular endothelial cells derived from bone
    • DOI 10.1074/jbc.M111093200
    • A. Ishida, N. Fujita, R. Kitazawa, and T. Tsuruo Transforming growth factor-beta induces expression of receptor activator of NF-kappa B ligand in vascular endothelial cells derived from bone J. Biol. Chem. 277 2002 26217 26224 (Pubitemid 34967109)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.29 , pp. 26217-26224
    • Ishida, A.1    Fujita, N.2    Kitazawa, R.3    Tsuruo, T.4
  • 18
    • 0026486816 scopus 로고
    • Pleiotropic effects of a null mutation in the c-fos proto-oncogene
    • R.S. Johnson, B.M. Spiegelman, and V. Papaioannou Pleiotropic effects of a null mutation in the c-fos proto-oncogene Cell 71 1992 577 586
    • (1992) Cell , vol.71 , pp. 577-586
    • Johnson, R.S.1    Spiegelman, B.M.2    Papaioannou, V.3
  • 19
    • 84864948721 scopus 로고    scopus 로고
    • Early growth response 2 negatively modulates osteoclast differentiation through upregulation of Id helix-loop-helix proteins
    • H.J. Kim, J.M. Hong, K.A. Yoon, N. Kim, D.W. Cho, J.Y. Choi, I.K. Lee, and S.Y. Kim Early growth response 2 negatively modulates osteoclast differentiation through upregulation of Id helix-loop-helix proteins Bone 51 2012 643 650
    • (2012) Bone , vol.51 , pp. 643-650
    • Kim, H.J.1    Hong, J.M.2    Yoon, K.A.3    Kim, N.4    Cho, D.W.5    Choi, J.Y.6    Lee, I.K.7    Kim, S.Y.8
  • 22
    • 84860715199 scopus 로고    scopus 로고
    • Effects of obovatol on GSH depleted glia-mediated neurotoxicity and oxidative damage
    • M. Lee, B.M. Kwon, K. Suk, E. McGeer, and P.L. McGeer Effects of obovatol on GSH depleted glia-mediated neurotoxicity and oxidative damage J. Neuroimmunol. Pharmacol. 7 2012 173 186
    • (2012) J. Neuroimmunol. Pharmacol. , vol.7 , pp. 173-186
    • Lee, M.1    Kwon, B.M.2    Suk, K.3    McGeer, E.4    McGeer, P.L.5
  • 23
    • 51649118760 scopus 로고    scopus 로고
    • Obovatol inhibits colorectal cancer growth by inhibiting tumor cell proliferation and inducing apoptosis
    • S.K. Lee, H.N. Kim, Y.R. Kang, C.W. Lee, H.M. Kim, D.C. Han, J. Shin, K. Bae, and B.M. Kwon Obovatol inhibits colorectal cancer growth by inhibiting tumor cell proliferation and inducing apoptosis Bioorg. Med. Chem. 16 2008 8397 8402
    • (2008) Bioorg. Med. Chem. , vol.16 , pp. 8397-8402
    • Lee, S.K.1    Kim, H.N.2    Kang, Y.R.3    Lee, C.W.4    Kim, H.M.5    Han, D.C.6    Shin, J.7    Bae, K.8    Kwon, B.M.9
  • 24
    • 39149104633 scopus 로고    scopus 로고
    • Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB
    • S.Y. Lee, D.Y. Yuk, H.S. Song, Y. Yoondo, J.K. Jung, D.C. Moon, B.S. Lee, and J.T. Hong Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB Eur. J. Pharmacol. 582 2008 17 25
    • (2008) Eur. J. Pharmacol. , vol.582 , pp. 17-25
    • Lee, S.Y.1    Yuk, D.Y.2    Song, H.S.3    Yoondo, Y.4    Jung, J.K.5    Moon, D.C.6    Lee, B.S.7    Hong, J.T.8
  • 26
    • 13244267455 scopus 로고    scopus 로고
    • Osteoclast-derived activity in the coupling of bone formation to resorption
    • DOI 10.1016/j.molmed.2004.12.004, PII S1471491404003132
    • T.J. Martin, and N.A. Sims Osteoclast-derived activity in the coupling of bone formation to resorption Trends Mol. Med. 11 2005 76 81 (Pubitemid 40193486)
    • (2005) Trends in Molecular Medicine , vol.11 , Issue.2 , pp. 76-81
    • Martin, T.J.1    Sims, N.A.2
  • 28
    • 84859766698 scopus 로고    scopus 로고
    • New regulation mechanisms of osteoclast differentiation
    • T. Nakashima, and H. Takayanagi New regulation mechanisms of osteoclast differentiation Ann. N.Y. Acad. Sci. 1240 2011 E13 18
    • (2011) Ann. N.Y. Acad. Sci. , vol.1240 , pp. 13-18
    • Nakashima, T.1    Takayanagi, H.2
  • 30
    • 77950202753 scopus 로고    scopus 로고
    • Obovatol attenuates microglia-mediated neuroinflammation by modulating redox regulation
    • J. Ock, H.S. Han, S.H. Hong, S.Y. Lee, Y.M. Han, B.M. Kwon, and K. Suk Obovatol attenuates microglia-mediated neuroinflammation by modulating redox regulation Br. J. Pharmacol. 159 2010 1646 1662
    • (2010) Br. J. Pharmacol. , vol.159 , pp. 1646-1662
    • Ock, J.1    Han, H.S.2    Hong, S.H.3    Lee, S.Y.4    Han, Y.M.5    Kwon, B.M.6    Suk, K.7
  • 31
    • 80052056767 scopus 로고    scopus 로고
    • Antiplatelet activity of obovatol, a biphenolic component of Magnolia Obovata, in rat arterial thrombosis and rabbit platelet aggregation
    • E.S. Park, Y. Lim, S.H. Lee, B.M. Kwon, H.S. Yoo, J.T. Hong, and Y.P. Yun Antiplatelet activity of obovatol, a biphenolic component of Magnolia Obovata, in rat arterial thrombosis and rabbit platelet aggregation J. Atheroscler. Thromb. 18 2011 659 669
    • (2011) J. Atheroscler. Thromb. , vol.18 , pp. 659-669
    • Park, E.S.1    Lim, Y.2    Lee, S.H.3    Kwon, B.M.4    Yoo, H.S.5    Hong, J.T.6    Yun, Y.P.7
  • 32
    • 0036594745 scopus 로고    scopus 로고
    • Anti-platelet effect of the constituents isolated from the barks and fruits of Magnolia obovata
    • M.K. Pyo, Y. Lee, and H.S. Yun-Choi Anti-platelet effect of the constituents isolated from the barks and fruits of Magnolia obovata Arch. Pharmacal. Res. 25 2002 325 328
    • (2002) Arch. Pharmacal. Res. , vol.25 , pp. 325-328
    • Pyo, M.K.1    Lee, Y.2    Yun-Choi, H.S.3
  • 33
    • 19344374949 scopus 로고    scopus 로고
    • IκB kinase (IKK)β, but not IKKα, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss
    • DOI 10.1084/jem.20042081
    • M.G. Ruocco, S. Maeda, J.M. Park, T. Lawrence, L.C. Hsu, Y. Cao, G. Schett, E.F. Wagner, and M. Karin I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss J. Exp. Med. 201 2005 1677 1687 (Pubitemid 40721011)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.10 , pp. 1677-1687
    • Ruocco, M.G.1    Maeda, S.2    Park, J.M.3    Lawrence, T.4    Hsu, L.-C.5    Cao, Y.6    Schett, G.7    Wagner, E.F.8    Karin, M.9
  • 35
    • 28544452658 scopus 로고    scopus 로고
    • Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system
    • S. Tanaka, K. Nakamura, N. Takahasi, and T. Suda Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system Immunol. Rev. 208 2005 30 49 (Pubitemid 41746383)
    • (2005) Immunological Reviews , vol.208 , pp. 30-49
    • Tanaka, S.1    Nakamura, K.2    Takahasi, N.3    Suda, T.4
  • 36
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • S.L. Teitelbaum Bone resorption by osteoclasts Science 289 2000 1504 1508
    • (2000) Science , vol.289 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 37
    • 33947497852 scopus 로고    scopus 로고
    • Osteoclasts: What do they do and how do they do it?
    • DOI 10.2353/ajpath.2007.060834
    • S.L. Teitelbaum Osteoclasts: what do they do and how do they do it? Am. J. Pathol. 170 2007 427 435 (Pubitemid 47339379)
    • (2007) American Journal of Pathology , vol.170 , Issue.2 , pp. 427-435
    • Teitelbaum, S.L.1
  • 38
    • 0043267732 scopus 로고    scopus 로고
    • Genetic regulation of osteoclast development and function
    • DOI 10.1038/nrg1122
    • S.L. Teitelbaum, and F.P. Ross Genetic regulation of osteoclast development and function Nat. Rev. Genet. 4 2003 638 649 (Pubitemid 36917505)
    • (2003) Nature Reviews Genetics , vol.4 , Issue.8 , pp. 638-649
    • Teitelbaum, S.L.1    Ross, F.P.2
  • 39
    • 75749109330 scopus 로고    scopus 로고
    • Bone development and inflammatory disease is regulated by AP-1 (Fos/Jun)
    • E.F. Wagner Bone development and inflammatory disease is regulated by AP-1 (Fos/Jun) Ann. Rheum. Dis. 69 Suppl. 1 2010 i86 88
    • (2010) Ann. Rheum. Dis. , vol.69 , Issue.SUPPL. 1 , pp. 86-88
    • Wagner, E.F.1
  • 41
    • 0031439265 scopus 로고    scopus 로고
    • TRANCE (Tumor necrosis factor [TNF]-related Activation-induced Cytokine), a new TNF family member predominantly expressed in t cells, is a dendritic cell-specific survival factor
    • DOI 10.1084/jem.186.12.2075
    • B.R. Wong, R. Josien, S.Y. Lee, B. Sauter, H.L. Li, R.M. Steinman, and Y. Choi TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor J. Exp. Med. 186 1997 2075 2080 (Pubitemid 28013694)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.12 , pp. 2075-2080
    • Wong, B.R.1    Josien, R.2    Lee, S.Y.3    Sauter, B.4    Li, H.-L.5    Steinman, R.M.6    Choi, Y.7
  • 42
    • 34547124586 scopus 로고    scopus 로고
    • NF-κB p50 and p52 regulate receptor activator of NF-κB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1
    • DOI 10.1074/jbc.M610701200
    • T. Yamashita, Z. Yao, F. Li, Q. Zhang, I.R. Badell, E.M. Schwarz, S. Takeshita, E.F. Wagner, M. Noda, K. Matsuo, L. Xing, and B.F. Boyce NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1 J. Biol. Chem. 282 2007 18245 18253 (Pubitemid 47100255)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.25 , pp. 18245-18253
    • Yamashita, T.1    Yao, Z.2    Li, F.3    Zhang, Q.4    Badell, I.R.5    Schwarz, E.M.6    Takeshita, S.7    Wagner, E.F.8    Noda, M.9    Matsuo, K.10    Xing, L.11    Boyce, B.F.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.