Calpain-6, a target molecule of glucocorticoids, regulates osteoclastic bone resorption via cytoskeletal organization and microtubule acetylation

Journal of Bone and Mineral Research

Volumn 26, Issue 3, 2011, Pages 657-665

  Hong, Jung Min ^a   Teitelbaum, Steven L ^b   Kim, Tae Ho ^a   Ross, F Patrick ^b   Kim, Shin Yoon ^a,c   Kim, Hyun Ju ^a,c  

^a Kyungpook National University Hospital   (South Korea)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Kyungpook National University School of Medicine   (South Korea)

Author keywords

C APN 6; cytoskeleton; glucocorticoids; microtubule; osteoclast

Indexed keywords

ACTIN; BETA3 INTEGRIN; CALPAIN; CALPAIN 6; DEXAMETHASONE; LENTIVIRUS VECTOR; MESSENGER RNA; PROTEIN; REGULATOR PROTEIN; RETROVIRUS VECTOR; SHORT HAIRPIN RNA; TUBULIN; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOSKELETON; DRUG MECHANISM; DRUG TARGETING; GENE OVEREXPRESSION; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MACROPHAGE; MICROTUBULE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING;

ACETYLATION; ANIMALS; BONE RESORPTION; CALPAIN; CELL MOVEMENT; CYTOSKELETON; DEXAMETHASONE; GENE KNOCKDOWN TECHNIQUES; GLUCOCORTICOIDS; INTEGRIN BETA3; MICE; MICE, INBRED C57BL; MICROTUBULES; OSTEOCLASTS; OSTEOGENESIS; UP-REGULATION;

EID: 79951822972     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.241     Document Type: Article

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