Obovatol attenuates microglia-mediated neuroinflammation by modulating redox regulation

British Journal of Pharmacology

Volumn 159, Issue 8, 2010, Pages 1646-1662

  Ock, Jiyeon ^a   Han, Hyung S ^a   Hong, Su H ^b   Lee, So Y ^c   Han, Young Min ^c   Kwon, Byoung Mog ^c   Suk, Kyoungho ^a  

^a Kyungpook National University School of Medicine   (South Korea)

^b Kyungpook National University   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Chemical genetics; Microglia; Neuroinflammation; Neuroprotection; Obovatol; Peroxiredoxin 2

Indexed keywords

ANTIINFLAMMATORY AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; OBOVATOL; PEROXIREDOXIN 2; REACTIVE OXYGEN METABOLITE; STAT1 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG STRUCTURE; ENZYME ACTIVATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MASS SPECTROMETRY; MICROGLIA; MOUSE; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANIMALS; BIPHENYL COMPOUNDS; BLOTTING, WESTERN; CELL LINE; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; INFLAMMATION; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED ICR; MICROGLIA; NITRIC OXIDE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATION-REDUCTION; PHENYL ETHERS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 77950202753     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00659.x     Document Type: Article

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