Antiplatelet activity of obovatol, a biphenolic component of magnolia obovata, in rat arterial thrombosis and rabbit platelet aggregation

Journal of Atherosclerosis and Thrombosis

Volumn 18, Issue 8, 2011, Pages 659-669

  Park, Eun Seok ^a   Lim, Yong ^b   Lee, Seung Ho ^a   Kwon, Byoung Mog ^c   Yoo, Hwan Soo ^a   Hong, Jin Tae ^a   Yun, Yeo Pyo ^a  

^a Chungbuk National University   (South Korea)

^b Dong Eui University   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Antiplatelet activity; FeCl3 induced thrombosis model; Obovatol; PLC 2; Thrombosis

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; ARACHIDONIC ACID; CALCIUM; OBOVATOL; PHOSPHOLIPASE C GAMMA2; PLANT EXTRACT; SEROTONIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY THROMBOSIS; ARTICLE; BLOOD CLOTTING TIME; CALCIUM MOBILIZATION; DRUG MECHANISM; ENZYME ACTIVATION; EX VIVO STUDY; IC 50; IN VITRO STUDY; IN VIVO STUDY; MAGNOLIA OBOVATA; MAGNOLIACEAE; MALE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; RAT; SEROTONIN RELEASE; THROMBOCYTE AGGREGATION;

ADMINISTRATION, ORAL; ANIMALS; ARTERIES; BIPHENYL COMPOUNDS; CALCIUM; DISEASE MODELS, ANIMAL; HUMANS; INHIBITORY CONCENTRATION 50; MAGNOLIA; MALE; PHENOL; PHENYL ETHERS; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PLANT EXTRACTS; PLATELET AGGREGATION; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; THROMBOSIS;

EID: 80052056767     PISSN: 13403478     EISSN: 18803873     Source Type: Journal    
DOI: 10.5551/jat.7427     Document Type: Article

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