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Volumn 10, Issue 1, 2014, Pages

C/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitors

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; APOPTOSIS; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; MICE;

EID: 84893744924     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004079     Document Type: Article
Times cited : (83)

References (62)
  • 1
    • 43749110075 scopus 로고    scopus 로고
    • Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal
    • Zon LI, (2008) Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal. Nature 453: 306-313.
    • (2008) Nature , vol.453 , pp. 306-313
    • Zon, L.I.1
  • 2
    • 84866129506 scopus 로고    scopus 로고
    • Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice
    • Rossi L, Lin KK, Boles NC, Yang L, King KY, et al. (2012) Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice. Cell Stem Cell 11: 302-317.
    • (2012) Cell Stem Cell , vol.11 , pp. 302-317
    • Rossi, L.1    Lin, K.K.2    Boles, N.C.3    Yang, L.4    King, K.Y.5
  • 3
    • 80052392586 scopus 로고    scopus 로고
    • Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice
    • Ng AP, Loughran SJ, Metcalf D, Hyland CD, de Graaf CA, et al. (2011) Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice. Blood 118: 2454-2461.
    • (2011) Blood , vol.118 , pp. 2454-2461
    • Ng, A.P.1    Loughran, S.J.2    Metcalf, D.3    Hyland, C.D.4    de Graaf, C.A.5
  • 4
    • 45549102935 scopus 로고    scopus 로고
    • The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells
    • Loughran SJ, Kruse EA, Hacking DF, de Graaf CA, Hyland CD, et al. (2008) The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells. Nature immunology 9: 810-819.
    • (2008) Nature Immunology , vol.9 , pp. 810-819
    • Loughran, S.J.1    Kruse, E.A.2    Hacking, D.F.3    de Graaf, C.A.4    Hyland, C.D.5
  • 5
    • 76049120037 scopus 로고    scopus 로고
    • Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation
    • Lieu YK, Reddy EP, (2009) Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation. Proceedings of the National Academy of Sciences of the United States of America 106: 21689-21694.
    • (2009) Proceedings of the National Academy of Sciences of the United States of America , vol.106 , pp. 21689-21694
    • Lieu, Y.K.1    Reddy, E.P.2
  • 6
    • 23944446085 scopus 로고    scopus 로고
    • Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation
    • Iwasaki H, Somoza C, Shigematsu H, Duprez EA, Iwasaki-Arai J, et al. (2005) Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation. Blood 106: 1590-1600.
    • (2005) Blood , vol.106 , pp. 1590-1600
    • Iwasaki, H.1    Somoza, C.2    Shigematsu, H.3    Duprez, E.A.4    Iwasaki-Arai, J.5
  • 7
    • 34547668398 scopus 로고    scopus 로고
    • Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells
    • Kim I, Saunders TL, Morrison SJ, (2007) Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells. Cell 130: 470-483.
    • (2007) Cell , vol.130 , pp. 470-483
    • Kim, I.1    Saunders, T.L.2    Morrison, S.J.3
  • 8
    • 7244231429 scopus 로고    scopus 로고
    • Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells
    • Hock H, Hamblen MJ, Rooke HM, Schindler JW, Saleque S, et al. (2004) Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells. Nature 431: 1002-1007.
    • (2004) Nature , vol.431 , pp. 1002-1007
    • Hock, H.1    Hamblen, M.J.2    Rooke, H.M.3    Schindler, J.W.4    Saleque, S.5
  • 9
    • 4644274431 scopus 로고    scopus 로고
    • Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival
    • Hock H, Meade E, Medeiros S, Schindler JW, Valk PJ, et al. (2004) Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival. Genes & development 18: 2336-2341.
    • (2004) Genes & Development , vol.18 , pp. 2336-2341
    • Hock, H.1    Meade, E.2    Medeiros, S.3    Schindler, J.W.4    Valk, P.J.5
  • 10
    • 10344258563 scopus 로고    scopus 로고
    • Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1
    • Iwama A, Oguro H, Negishi M, Kato Y, Morita Y, et al. (2004) Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity 21: 843-851.
    • (2004) Immunity , vol.21 , pp. 843-851
    • Iwama, A.1    Oguro, H.2    Negishi, M.3    Kato, Y.4    Morita, Y.5
  • 11
    • 0038349957 scopus 로고    scopus 로고
    • Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
    • Park IK, Qian D, Kiel M, Becker MW, Pihalja M, et al. (2003) Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 423: 302-305.
    • (2003) Nature , vol.423 , pp. 302-305
    • Park, I.K.1    Qian, D.2    Kiel, M.3    Becker, M.W.4    Pihalja, M.5
  • 12
    • 70350654370 scopus 로고    scopus 로고
    • DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
    • Broske AM, Vockentanz L, Kharazi S, Huska MR, Mancini E, et al. (2009) DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nature genetics 41: 1207-1215.
    • (2009) Nature Genetics , vol.41 , pp. 1207-1215
    • Broske, A.M.1    Vockentanz, L.2    Kharazi, S.3    Huska, M.R.4    Mancini, E.5
  • 13
    • 70349469788 scopus 로고    scopus 로고
    • DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
    • Trowbridge JJ, Snow JW, Kim J, Orkin SH, (2009) DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. Cell Stem Cell 5: 442-449.
    • (2009) Cell Stem Cell , vol.5 , pp. 442-449
    • Trowbridge, J.J.1    Snow, J.W.2    Kim, J.3    Orkin, S.H.4
  • 14
    • 34548462072 scopus 로고    scopus 로고
    • Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors
    • Jude CD, Climer L, Xu D, Artinger E, Fisher JK, et al. (2007) Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors. Cell Stem Cell 1: 324-337.
    • (2007) Cell Stem Cell , vol.1 , pp. 324-337
    • Jude, C.D.1    Climer, L.2    Xu, D.3    Artinger, E.4    Fisher, J.K.5
  • 16
    • 41749108163 scopus 로고    scopus 로고
    • Stem cell regulation by polycomb repressors: postponing commitment
    • Pietersen AM, van Lohuizen M, (2008) Stem cell regulation by polycomb repressors: postponing commitment. Current opinion in cell biology 20: 201-207.
    • (2008) Current Opinion in Cell Biology , vol.20 , pp. 201-207
    • Pietersen, A.M.1    van Lohuizen, M.2
  • 17
    • 84857192635 scopus 로고    scopus 로고
    • FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors
    • Mancini E, Sanjuan-Pla A, Luciani L, Moore S, Grover A, et al. (2012) FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors. The EMBO journal 31: 351-365.
    • (2012) The EMBO Journal , vol.31 , pp. 351-365
    • Mancini, E.1    Sanjuan-Pla, A.2    Luciani, L.3    Moore, S.4    Grover, A.5
  • 18
    • 22344437854 scopus 로고    scopus 로고
    • Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage
    • Porse BT, Bryder D, Theilgaard-Monch K, Hasemann MS, Anderson K, et al. (2005) Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage. J Exp Med 202: 85-96.
    • (2005) J Exp Med , vol.202 , pp. 85-96
    • Porse, B.T.1    Bryder, D.2    Theilgaard-Monch, K.3    Hasemann, M.S.4    Anderson, K.5
  • 19
    • 0035913913 scopus 로고    scopus 로고
    • E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo
    • Porse BT, Pedersen TA, Xu X, Lindberg B, Wewer UM, et al. (2001) E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo. Cell 107: 247-258.
    • (2001) Cell , vol.107 , pp. 247-258
    • Porse, B.T.1    Pedersen, T.A.2    Xu, X.3    Lindberg, B.4    Wewer, U.M.5
  • 21
    • 10344230611 scopus 로고    scopus 로고
    • Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha
    • Zhang P, Iwasaki-Arai J, Iwasaki H, Fenyus ML, Dayaram T, et al. (2004) Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha. Immunity 21: 853-863.
    • (2004) Immunity , vol.21 , pp. 853-863
    • Zhang, P.1    Iwasaki-Arai, J.2    Iwasaki, H.3    Fenyus, M.L.4    Dayaram, T.5
  • 22
    • 70350497395 scopus 로고    scopus 로고
    • Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML
    • Bereshchenko O, Mancini E, Moore S, Bilbao D, Mansson R, et al. (2009) Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML. Cancer Cell 16: 390-400.
    • (2009) Cancer Cell , vol.16 , pp. 390-400
    • Bereshchenko, O.1    Mancini, E.2    Moore, S.3    Bilbao, D.4    Mansson, R.5
  • 23
    • 84876482887 scopus 로고    scopus 로고
    • C/EBPa controls acquisition and maintenance of adult haematopoietic stem cell quiescence
    • Ye M, Zhang H, Amabile G, Yang H, Staber PB, et al. (2013) C/EBPa controls acquisition and maintenance of adult haematopoietic stem cell quiescence. Nature cell biology 15 (4) (): 385-94.
    • (2013) Nature Cell Biology , vol.15 , Issue.4 , pp. 385-394
    • Ye, M.1    Zhang, H.2    Amabile, G.3    Yang, H.4    Staber, P.B.5
  • 25
    • 21644462493 scopus 로고    scopus 로고
    • Molecular stop signs: regulation of cell-cycle arrest by C/EBP transcription factors
    • Johnson PF, (2005) Molecular stop signs: regulation of cell-cycle arrest by C/EBP transcription factors. J Cell Sci 118: 2545-2555.
    • (2005) J Cell Sci , vol.118 , pp. 2545-2555
    • Johnson, P.F.1
  • 26
    • 73949103238 scopus 로고    scopus 로고
    • The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis
    • Kimura A, Rieger MA, Simone JM, Chen W, Wickre MC, et al. (2009) The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis. Blood 114: 4721-4728.
    • (2009) Blood , vol.114 , pp. 4721-4728
    • Kimura, A.1    Rieger, M.A.2    Simone, J.M.3    Chen, W.4    Wickre, M.C.5
  • 27
    • 0028900074 scopus 로고
    • DNA-binding specificity of NGFI-A and related zinc finger transcription factors
    • Swirnoff AH, Milbrandt J, (1995) DNA-binding specificity of NGFI-A and related zinc finger transcription factors. Molecular and Cellular Biology 15: 2275-2287.
    • (1995) Molecular and Cellular Biology , vol.15 , pp. 2275-2287
    • Swirnoff, A.H.1    Milbrandt, J.2
  • 28
    • 84857190947 scopus 로고    scopus 로고
    • Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling
    • Seiler MP, Mathew R, Liszewski MK, Spooner CJ, Barr K, et al. (2012) Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling. Nature immunology 13: 264-271.
    • (2012) Nature Immunology , vol.13 , pp. 264-271
    • Seiler, M.P.1    Mathew, R.2    Liszewski, M.K.3    Spooner, C.J.4    Barr, K.5
  • 30
    • 35148865583 scopus 로고    scopus 로고
    • Regulation of the extrinsic apoptotic pathway by the extracellular matrix glycoprotein EMILIN2
    • Mongiat M, Ligresti G, Marastoni S, Lorenzon E, Doliana R, et al. (2007) Regulation of the extrinsic apoptotic pathway by the extracellular matrix glycoprotein EMILIN2. Molecular and cellular biology 27: 7176-7187.
    • (2007) Molecular and Cellular Biology , vol.27 , pp. 7176-7187
    • Mongiat, M.1    Ligresti, G.2    Marastoni, S.3    Lorenzon, E.4    Doliana, R.5
  • 31
    • 84860215207 scopus 로고    scopus 로고
    • Molecular mechanisms and potential functions of histone demethylases
    • Kooistra SM, Helin K, (2012) Molecular mechanisms and potential functions of histone demethylases. Nature reviews Molecular cell biology 13: 297-311.
    • (2012) Nature Reviews Molecular Cell Biology , vol.13 , pp. 297-311
    • Kooistra, S.M.1    Helin, K.2
  • 32
    • 79952534189 scopus 로고    scopus 로고
    • Regulation of chromatin by histone modifications
    • Bannister AJ, Kouzarides T, (2011) Regulation of chromatin by histone modifications. Cell research 21: 381-395.
    • (2011) Cell Research , vol.21 , pp. 381-395
    • Bannister, A.J.1    Kouzarides, T.2
  • 33
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, et al. (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125: 315-326.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3    Kamal, M.4    Huebert, D.J.5
  • 34
  • 35
    • 79960064353 scopus 로고    scopus 로고
    • Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
    • Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O, Ndiaye-Lobry D, et al. (2011) Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 20: 11-24.
    • (2011) Cancer Cell , vol.20 , pp. 11-24
    • Moran-Crusio, K.1    Reavie, L.2    Shih, A.3    Abdel-Wahab, O.4    Ndiaye-Lobry, D.5
  • 36
    • 79960062301 scopus 로고    scopus 로고
    • TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
    • Quivoron C, Couronne L, Della Valle V, Lopez CK, Plo I, et al. (2011) TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 20: 25-38.
    • (2011) Cancer Cell , vol.20 , pp. 25-38
    • Quivoron, C.1    Couronne, L.2    Della Valle, V.3    Lopez, C.K.4    Plo, I.5
  • 37
    • 79956302047 scopus 로고    scopus 로고
    • TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
    • Williams K, Christensen J, Pedersen MT, Johansen JV, Cloos PA, et al. (2011) TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473: 343-348.
    • (2011) Nature , vol.473 , pp. 343-348
    • Williams, K.1    Christensen, J.2    Pedersen, M.T.3    Johansen, J.V.4    Cloos, P.A.5
  • 38
    • 79551587102 scopus 로고    scopus 로고
    • Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells
    • Koh KP, Yabuuchi A, Rao S, Huang Y, Cunniff K, et al. (2011) Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell 8: 200-213.
    • (2011) Cell Stem Cell , vol.8 , pp. 200-213
    • Koh, K.P.1    Yabuuchi, A.2    Rao, S.3    Huang, Y.4    Cunniff, K.5
  • 39
    • 79961125686 scopus 로고    scopus 로고
    • Tet1 and 5-hydroxymethylation: a genome-wide view in mouse embryonic stem cells
    • Wu H, Zhang Y, (2011) Tet1 and 5-hydroxymethylation: a genome-wide view in mouse embryonic stem cells. Cell Cycle 10: 2428-2436.
    • (2011) Cell Cycle , vol.10 , pp. 2428-2436
    • Wu, H.1    Zhang, Y.2
  • 41
    • 67149091317 scopus 로고    scopus 로고
    • Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion
    • Sato T, Onai N, Yoshihara H, Arai F, Suda T, et al. (2009) Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion. Nature medicine 15: 696-700.
    • (2009) Nature Medicine , vol.15 , pp. 696-700
    • Sato, T.1    Onai, N.2    Yoshihara, H.3    Arai, F.4    Suda, T.5
  • 42
    • 33646351002 scopus 로고    scopus 로고
    • PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
    • Zhang J, Grindley JC, Yin T, Jayasinghe S, He XC, et al. (2006) PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature 441: 518-522.
    • (2006) Nature , vol.441 , pp. 518-522
    • Zhang, J.1    Grindley, J.C.2    Yin, T.3    Jayasinghe, S.4    He, X.C.5
  • 43
    • 33646376411 scopus 로고    scopus 로고
    • Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
    • Yilmaz OH, Valdez R, Theisen BK, Guo W, Ferguson DO, et al. (2006) Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441: 475-482.
    • (2006) Nature , vol.441 , pp. 475-482
    • Yilmaz, O.H.1    Valdez, R.2    Theisen, B.K.3    Guo, W.4    Ferguson, D.O.5
  • 44
    • 0037100304 scopus 로고    scopus 로고
    • Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: possible role in lineage commitment decisions
    • Reddy VA, Iwama A, Iotzova G, Schulz M, Elsasser A, et al. (2002) Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: possible role in lineage commitment decisions. Blood 100: 483-490.
    • (2002) Blood , vol.100 , pp. 483-490
    • Reddy, V.A.1    Iwama, A.2    Iotzova, G.3    Schulz, M.4    Elsasser, A.5
  • 45
    • 0029793902 scopus 로고    scopus 로고
    • PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells
    • Smith LT, Hohaus S, Gonzalez DA, Dziennis SE, Tenen DG, (1996) PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells. Blood 88: 1234-1247.
    • (1996) Blood , vol.88 , pp. 1234-1247
    • Smith, L.T.1    Hohaus, S.2    Gonzalez, D.A.3    Dziennis, S.E.4    Tenen, D.G.5
  • 46
    • 84876860619 scopus 로고    scopus 로고
    • Sustained PU.1 Levels Balance Cell-Cycle Regulators to Prevent Exhaustion of Adult Hematopoietic Stem Cells
    • Staber PB, Zhang P, Ye M, Welner RS, Nombela-Arrieta C, et al. (2013) Sustained PU.1 Levels Balance Cell-Cycle Regulators to Prevent Exhaustion of Adult Hematopoietic Stem Cells. Molecular cell 49: 934-946.
    • (2013) Molecular Cell , vol.49 , pp. 934-946
    • Staber, P.B.1    Zhang, P.2    Ye, M.3    Welner, R.S.4    Nombela-Arrieta, C.5
  • 47
    • 71449125977 scopus 로고    scopus 로고
    • Forcing cells to change lineages
    • Graf T, Enver T, (2009) Forcing cells to change lineages. Nature 462: 587-594.
    • (2009) Nature , vol.462 , pp. 587-594
    • Graf, T.1    Enver, T.2
  • 48
    • 77449145533 scopus 로고    scopus 로고
    • Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1
    • Challen GA, Boles NC, Chambers SM, Goodell MA, (2010) Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell 6: 265-278.
    • (2010) Cell Stem Cell , vol.6 , pp. 265-278
    • Challen, G.A.1    Boles, N.C.2    Chambers, S.M.3    Goodell, M.A.4
  • 49
    • 34547692981 scopus 로고    scopus 로고
    • Long-term propagation of distinct hematopoietic differentiation programs in vivo
    • Dykstra B, Kent D, Bowie M, McCaffrey L, Hamilton M, et al. (2007) Long-term propagation of distinct hematopoietic differentiation programs in vivo. Cell Stem Cell 1: 218-229.
    • (2007) Cell Stem Cell , vol.1 , pp. 218-229
    • Dykstra, B.1    Kent, D.2    Bowie, M.3    McCaffrey, L.4    Hamilton, M.5
  • 51
    • 34547133494 scopus 로고    scopus 로고
    • The C/EBP family of transcription factors: a paradigm for interaction between gene expression and proliferation control
    • Nerlov C, (2007) The C/EBP family of transcription factors: a paradigm for interaction between gene expression and proliferation control. Trends in cell biology 17: 318-324.
    • (2007) Trends in Cell Biology , vol.17 , pp. 318-324
    • Nerlov, C.1
  • 52
    • 60749112787 scopus 로고    scopus 로고
    • The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells
    • Lazarevic V, Zullo AJ, Schweitzer MN, Staton TL, Gallo EM, et al. (2009) The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells. Nature immunology 10: 306-313.
    • (2009) Nature Immunology , vol.10 , pp. 306-313
    • Lazarevic, V.1    Zullo, A.J.2    Schweitzer, M.N.3    Staton, T.L.4    Gallo, E.M.5
  • 53
    • 79954992737 scopus 로고    scopus 로고
    • Early growth response gene-2 (Egr-2) regulates the development of B and T cells
    • Li S, Symonds AL, Zhu B, Liu M, Raymond MV, et al. (2011) Early growth response gene-2 (Egr-2) regulates the development of B and T cells. PLoS One 6: e18498.
    • (2011) PLoS One , vol.6
    • Li, S.1    Symonds, A.L.2    Zhu, B.3    Liu, M.4    Raymond, M.V.5
  • 55
    • 2542455620 scopus 로고    scopus 로고
    • Stepwise reprogramming of B cells into macrophages
    • Xie H, Ye M, Feng R, Graf T, (2004) Stepwise reprogramming of B cells into macrophages. Cell 117: 663-676.
    • (2004) Cell , vol.117 , pp. 663-676
    • Xie, H.1    Ye, M.2    Feng, R.3    Graf, T.4
  • 56
    • 63849197532 scopus 로고    scopus 로고
    • Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features
    • Figueroa ME, Wouters BJ, Skrabanek L, Glass J, Li Y, et al. (2009) Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features. Blood 113: 2795-2804.
    • (2009) Blood , vol.113 , pp. 2795-2804
    • Figueroa, M.E.1    Wouters, B.J.2    Skrabanek, L.3    Glass, J.4    Li, Y.5
  • 57
    • 84885692432 scopus 로고    scopus 로고
    • Lack of the p42 form of C/EBPalpha leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors
    • Schuster MB, Frank AK, Bagger FO, Rapin N, Vikesaa J, et al. (2013) Lack of the p42 form of C/EBPalpha leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors. Experimental Hematology 41: 882-e816, 882-893, e816.
    • (2013) Experimental Hematology , vol.41 , pp. 816-882
    • Schuster, M.B.1    Frank, A.K.2    Bagger, F.O.3    Rapin, N.4    Vikesaa, J.5
  • 58
    • 44149104364 scopus 로고    scopus 로고
    • NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements
    • Weischenfeldt J, Damgaard I, Bryder D, Theilgaard-Monch K, Thoren LA, et al. (2008) NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements. Genes Dev 22: 1381-1396.
    • (2008) Genes Dev , vol.22 , pp. 1381-1396
    • Weischenfeldt, J.1    Damgaard, I.2    Bryder, D.3    Theilgaard-Monch, K.4    Thoren, L.A.5
  • 60
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead B, Trapnell C, Pop M, Salzberg SL, (2009) Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome biology 10: R25.
    • (2009) Genome Biology , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.