GpIbα interacts exclusively with exosite II of thrombin

Journal of Molecular Biology

Volumn 426, Issue 4, 2014, Pages 881-893

  Lechtenberg, Bernhard C ^a   Freund, Stefan M V ^b   Huntington, James A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

crystallography; exosite; haemostasis; NMR; platelet

Indexed keywords

GLYCOPROTEIN IB ALPHA; THROMBIN; ANION; PEPTIDE; PROTEINASE ACTIVATED RECEPTOR 1;

ARTICLE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; EXTRACELLULAR SPACE; MUTATIONAL ANALYSIS; PEPTIDE ANALYSIS; RECEPTOR BINDING; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE MEMBRANE;

CRYSTALLOGRAPHY; D-PHENYLALANYL-L-PROLYL-L-ARGININE CHLOROMETHYL KETONE; EXOSITE; GLYCOPROTEIN IBΑ; GPIBΑ; HAEMOSTASIS; LEUCINE-RICH REPEAT; LRR; NMR; PAR; PEG; PLATELET; POLYETHYLENE GLYCOL; PPACK; PROTEASE-ACTIVATED RECEPTOR; SPR; SURFACE PLASMON RESONANCE; THROMBOMODULIN; TM; TRANSVERSE RELAXATION OPTIMISED SPECTROSCOPY; TROSY;

AMINO ACID CHLOROMETHYL KETONES; ANTITHROMBINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PROTEIN CONFORMATION; RECEPTOR, PAR-1; THROMBIN;

EID: 84893638511     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.11.027     Document Type: Article

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