Platelet Glycoprotein Ibα Binds to Thrombin Anion-binding Exosite II Inducing Allosteric Changes in the Activity of Thrombin

Journal of Biological Chemistry

Volumn 276, Issue 9, 2001, Pages 6161-6168

  Li, Chester Q ^a   Vindigni, Alessandro ^a   Sadler, J Evan ^a   Wardell, Mark R ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b New Century Pharmaceuticals Incorporated   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR WEIGHT; MUTAGENESIS; PROTEINS; SODIUM CHLORIDE;

GLYCOPROTEINS;

BLOOD;

GLYCOPROTEIN IB; HIRUDIN; THROMBIN; THROMBIN RECEPTOR; DRUG DERIVATIVE; FIBRINOPEPTIDE A; GLYCOCALICIN; HIRUDIN DERIVATIVE; HIRUGEN; LOW MOLECULAR WEIGHT HEPARIN; PEPTIDE FRAGMENT; RECOMBINANT PROTEIN; SODIUM CHLORIDE;

ALLOSTERISM; ARTICLE; BINDING KINETICS; CONTROLLED STUDY; HUMAN; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; THROMBOCYTE ACTIVATION; CHEMISTRY; METABOLISM; SECRETION;

FIBRINOPEPTIDE A; HEPARIN, LOW-MOLECULAR-WEIGHT; HIRUDINS; HUMANS; PEPTIDE FRAGMENTS; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; RECOMBINANT PROTEINS; SODIUM CHLORIDE; THROMBIN;

EID: 0035794133     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M004164200     Document Type: Article

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