Silymarin ameliorates fructose induced insulin resistance syndrome by reducing de novo hepatic lipogenesis in the rat

European Journal of Pharmacology

Volumn 727, Issue 1, 2014, Pages 15-28

  Prakash, Prem ^a   Singh, Vishal ^a   Jain, Manish ^a   Rana, Minakshi ^a   Khanna, Vivek ^a   Barthwal, Manoj Kumar ^a   Dikshit, Madhu ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Fatty liver diseases; Fructose diet; Hepatic de novo lipogenesis; Insulin resistance syndrome; Myocardial ischemia reperfusion injury; Silymarin

Indexed keywords

BIOLOGICAL MARKER; FRUCTOSE; SILYMARIN;

ANIMAL; BLOOD; DISEASE MODEL; DOSE RESPONSE; DOWN REGULATION; DRUG ADMINISTRATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; INSULIN RESISTANCE; LIPOGENESIS; LIVER; MALE; METABOLISM; MYOCARDIAL REPERFUSION INJURY; ORAL DRUG ADMINISTRATION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOSIS; TIME; VASCULAR ENDOTHELIUM; VASODILATATION; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL MARKERS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG ADMINISTRATION SCHEDULE; ENDOTHELIUM, VASCULAR; FRUCTOSE; GENE EXPRESSION REGULATION; INSULIN RESISTANCE; LIPOGENESIS; LIVER; MALE; MYOCARDIAL REPERFUSION INJURY; OXIDATIVE STRESS; PLATELET ADHESIVENESS; PLATELET AGGREGATION; RATS, WISTAR; SIGNAL TRANSDUCTION; SILYMARIN; THROMBOSIS; TIME FACTORS; VASODILATION;

EID: 84893461287     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.01.038     Document Type: Article

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