Atorvastatin reduces tissue factor expression in adipose tissue of atherosclerotic rabbits

International Journal of Cardiology

Volumn 115, Issue 2, 2007, Pages 229-234

  Li, Jie Qi ^a   Zhao, Shui Ping ^b   Li, Quan Zhong ^c   Cai, Yun Chang ^d   Wu, Li Rong ^a   Fang, Ying ^a   Li, Ping ^a  

^a GUIZHOU MEDICAL UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c GUILIN MEDICAL UNIVERSITY   (China)

^d Department of Cardiology   (China)

Author keywords

Adipose tissue adipocyte; Atherosclerosis; Atorvastatin; Mevalonate; Tissue factor

Indexed keywords

ATORVASTATIN; CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; MEVALONIC ACID; STARCH; THROMBOPLASTIN;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CELL CULTURE; CHOLESTEROL DIET; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RABBIT; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ATHEROSCLEROSIS; HEPTANOIC ACIDS; MALE; PYRROLES; RABBITS; SUBCUTANEOUS FAT; THROMBOPLASTIN;

EID: 33846344918     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2006.02.007     Document Type: Article

References (27)

1. Juhan-Vague I., and Alessi M.C. PAI-1, obesity, insulin resistance and risk of cardiovascular events. Thromb Haemost 78 (1997) 656-660
2. Avellone G., Di Garbo V., Cordova R., et al. Blood coagulation and fibrinolysis in obese NIDDM patients. Diabetes Res (1994) 85-92
3. Samad F., Pandey M., and Loskutoff D.J. Tissue factor gene expression in the adipose tissues of obese mice. Proc Natl Acad Sci USA 95 13 (1998) 7591-7596
4. Loskutoff D.J., Fujisawa K., and Samad F. The fat mouse. A powerful genetic model to study hemostatic gene expression in obesity/NIDDM. Ann N Y Acad Sci 902 (2000) 272-281
5. Samad F., Pandey M., and Loskutoff D.J. Regulation of tissue factor gene expression in obesity. Blood 98 12 (2001) 3353-3358
6. Loskutoff D., and Samad F. The adipocyte and hemostatin balance in obesity. Aterioscler Thromb Vasc Biol 18 1 (1998) 1-6
7. Zhao S.P., Li J., Xu Z., Wu J., Li Q., and Ye H. Fenofibrate inhibits thrombogenic and fibrinolytic factors expression in adipose tissue of atherosclerotic rabbits. Clin Chim Acta 349 1-2 (2004) 81-86
8. Tremoli E., Camera M., Toschi V., and Colli S. Tissue factor in atherosclerosis. Atherosclerosis 144 (1999) 273-283
9. Taubman M.B., Fallon J.T., Schecter A.D., et al. Tissue factor in the pathogenesis of atherosclerosis. Thromb Haemost 78 (1997) 200-204
10. Khechai F., Ollivier F., Bridey M., Amar M., Hakim J., and Prost D. Effect of advanced glycation end product-modified albumin on tissue factor expression by monocytes. Arterioscler Thromb Vasc Biol 17 (1997) 2885-2890
11. Key N.S., Slungaard A., and Dandelet L. Whole blood tissue factor procoagulant activity is elevated in patients with sickle cell disease. Blood 91 (1998) 4216-4223
12. Krysiak R., Okopien B., and Herman Z. Effects of HMG-CoA reductase inhibitors on coagulation and fibrinolysis processes. Drug 63 17 (2003) 1821-1854
13. Sacks F.M., Pfeffer M.A., and Moye L.A. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and recurrent events trial investigators. N Engl J Med 335 (1996) 1001-1009
14. Baetta R., Camera M., Comparato C., Altana C., Ezekowitz M.D., and Tremoli E. Fluvastatin reduces tissue factor expression and macrophage accumulation in carotid lesions of cholesterol-fed rabbits in the absence of lipid lowering. Arterioscler Thromb Vasc Biol 22 (2002) 692-698
15. Sukhova G.K., Williams J.K., and Libby P. Statins reduce inflammation in atheroma of nonhuman primates independent of effects on serum cholesterol. Aterioscler Thromb Vasc Biol 22 (2002) 1452-1458
16. Brandes R.P., Beer S., and Ha T. Withdrawal of cerivastatin induces monocyte chemoattractant protein 1 and tissue factor expression in cultured vascular smooth muscle cells. Aterioscler Thromb Vasc Biol 23 (2003) 1794-1800
17. Eto M., Kozai T., and Cosentino F. Statin prevents tissue factor expression in human endothelial cells. Circulation 105 (2002) 1756-1759
18. Bea F., Blessing E., Shelley M.I., et al. Simvastatin inhibits expression of tissue factor in advanced atherosclerotic lesions of apolipoprotein E deficient mice independently of lipid lowering: potential role of simvastatin-mediated inhibition of Egr-1 expression and activation. Atherosclerosis 167 (2003) 187-194
19. Markle R.A., Han J., Summers B.D., et al. Pitavastatin alters the expression of thrombotic and fibrinolytic proteins in human vascular cells. J Cell Biochem 90 (2003) 23-32
20. Ishibashi T., Sakamoto T., Ohkawara H., et al. Intergral role of RhoA activation in monocyte adhesion-triggered tissue factor expression in endothelial cells. Arterioscler Thromb Vasc Biol 23 (2003) 681-687
21. Nagata K., Ishibashi T., Sakamoto T., et al. Rho/Rho-kinase is involved in the synthesis of tissue factor in human monocytes. Atherosclerosis 163 1 (2002) 39-47
22. Cabrero A., Alegret M., and Sanchez R.M. Bezafibrate reduces mRNA levels of adipocyte markers and increases fatty acid oxidation in primary culture of adipocytes. Diabetes 50 (2001) 1883-1890
23. Zhang H.H., Kumar S., Barnett A.H., and Eggo M.C. Ceiling culture of mature human adipocytes: use in studies of adipocyte functions. J Endocrinol 164 2 (2000) 119-128
24. Aikawa M., Voglic S.J., Sugiyama S.E., et al. Dietary lipid lowering reduces tissue factor expression in rabbit atheroma. Circulation 100 17 (1999) 1215-1222
25. Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study Group. Lancet 344 (1994) 1383-1389
26. Rosenson R.S. Non-lipid-lowering effects of statins on atherosclerosis. Curr Cardiol Rep 1 3 (1999) 225-232
27. Bettina H., Robert K., Karin H.T., et al. Simvastatin suppresses tissue factor expression and increases fibrinolytic activity in tumor necrosis factor-[alpha]-activated human peritoneal mesothelial cells. Kidney Int 63 6 (2003) 2065-2074