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Volumn 28, Issue SUPPL 1, 2013, Pages 105-111

Family with sequence similarity 3 gene family and nonalcoholic fatty liver disease

Author keywords

FAM3 gene family; NAFLD; PANDER; Steatosis

Indexed keywords

CYTOKINE; FAMILY WITH SEQUENCE SIMILARITY 3 PROTEIN; FAMILY WITH SEQUENCE SIMILARITY 3A PROTEIN; FAMILY WITH SEQUENCE SIMILARITY 3B PROTEIN; FAMILY WITH SEQUENCE SIMILARITY 3C PROTEIN; FAMILY WITH SEQUENCE SIMILARITY 3D PROTEIN; FAS ANTIGEN; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

EID: 84880402879     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/jgh.12033     Document Type: Review
Times cited : (25)

References (73)
  • 1
    • 34547460043 scopus 로고    scopus 로고
    • Metabolic liver disease of obesity and role of adipose tissue in the pathogenesis of nonalcoholic fatty liver disease
    • Qureshi K, Abrams GA. Metabolic liver disease of obesity and role of adipose tissue in the pathogenesis of nonalcoholic fatty liver disease. World J. Gastroenterol. 2007; 13: 3540-3553.
    • (2007) World J. Gastroenterol. , vol.13 , pp. 3540-3553
    • Qureshi, K.1    Abrams, G.A.2
  • 2
    • 77950858243 scopus 로고    scopus 로고
    • Pathology of nonalcoholic fatty liver disease
    • Brunt EM. Pathology of nonalcoholic fatty liver disease. Nat. Rev. 2010; 7: 195-203.
    • (2010) Nat. Rev. , vol.7 , pp. 195-203
    • Brunt, E.M.1
  • 3
    • 77951456114 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection
    • Starley BQ, Calcagno CJ, Harrison SA. Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection. Hepatology (Baltimore, Md.) 2010; 51: 1820-1832.
    • (2010) Hepatology (Baltimore, Md.) , vol.51 , pp. 1820-1832
    • Starley, B.Q.1    Calcagno, C.J.2    Harrison, S.A.3
  • 4
    • 80052558297 scopus 로고    scopus 로고
    • Prevalence of non-alcoholic fatty liver disease and its relation to hypoadiponectinaemia in the middle-aged and elderly Chinese population
    • Yang Z, Wang X, Wen J etal. Prevalence of non-alcoholic fatty liver disease and its relation to hypoadiponectinaemia in the middle-aged and elderly Chinese population. Arch. Med. Sci. 2011; 7: 665-672.
    • (2011) Arch. Med. Sci. , vol.7 , pp. 665-672
    • Yang, Z.1    Wang, X.2    Wen, J.3
  • 5
    • 56949097660 scopus 로고    scopus 로고
    • Epidemiology of non-alcoholic fatty liver disease in China
    • Fan JG, Farrell GC. Epidemiology of non-alcoholic fatty liver disease in China. J. Hepatol. 2009; 50: 204-210.
    • (2009) J. Hepatol. , vol.50 , pp. 204-210
    • Fan, J.G.1    Farrell, G.C.2
  • 6
    • 77951900252 scopus 로고    scopus 로고
    • Emerging molecular targets for the treatment of nonalcoholic fatty liver disease
    • Musso G, Gambino R, Cassader M. Emerging molecular targets for the treatment of nonalcoholic fatty liver disease. Annu. Rev. Med. 2010; 61: 375-392.
    • (2010) Annu. Rev. Med. , vol.61 , pp. 375-392
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 9
    • 79961002859 scopus 로고    scopus 로고
    • Adipose triglyceride lipase: a new target in the regulation of lipolysis by insulin
    • Chakrabarti P, Kandror KV. Adipose triglyceride lipase: a new target in the regulation of lipolysis by insulin. Curr. Diabetes Rev. 2011; 7: 270-277.
    • (2011) Curr. Diabetes Rev. , vol.7 , pp. 270-277
    • Chakrabarti, P.1    Kandror, K.V.2
  • 10
    • 52649158262 scopus 로고    scopus 로고
    • Ectopic fat and insulin resistance
    • Lettner A, Roden M. Ectopic fat and insulin resistance. Curr. Diab. Rep. 2008; 8: 185-191.
    • (2008) Curr. Diab. Rep. , vol.8 , pp. 185-191
    • Lettner, A.1    Roden, M.2
  • 11
    • 41849123475 scopus 로고    scopus 로고
    • Cytokines in the pathogenesis of fatty liver and disease progression to steatohepatitis: implications for treatment
    • Carter-Kent C, Zein NN, Feldstein AE. Cytokines in the pathogenesis of fatty liver and disease progression to steatohepatitis: implications for treatment. Am. J. Gastroenterol. 2008; 103: 1036-1042.
    • (2008) Am. J. Gastroenterol. , vol.103 , pp. 1036-1042
    • Carter-Kent, C.1    Zein, N.N.2    Feldstein, A.E.3
  • 13
    • 66349089511 scopus 로고    scopus 로고
    • Effects of adiponectin transgenic expression in liver of nonalcoholic steatohepatitis model mice
    • Nakayama H, Otabe S, Yuan X etal. Effects of adiponectin transgenic expression in liver of nonalcoholic steatohepatitis model mice. Metabolism 2009; 58: 901-908.
    • (2009) Metabolism , vol.58 , pp. 901-908
    • Nakayama, H.1    Otabe, S.2    Yuan, X.3
  • 14
    • 34547097768 scopus 로고    scopus 로고
    • Overexpression of human adiponectin in transgenic mice results in suppression of fat accumulation and prevention of premature death by high-calorie diet
    • Otabe S, Yuan X, Fukutani T etal. Overexpression of human adiponectin in transgenic mice results in suppression of fat accumulation and prevention of premature death by high-calorie diet. Am. J. Physiol. 2007; 293: E210-218.
    • (2007) Am. J. Physiol. , vol.293
    • Otabe, S.1    Yuan, X.2    Fukutani, T.3
  • 15
    • 54449085766 scopus 로고    scopus 로고
    • Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury
    • Zhou M, Xu A, Tam PK etal. Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury. Hepatology 2008; 48: 1087-1096.
    • (2008) Hepatology , vol.48 , pp. 1087-1096
    • Zhou, M.1    Xu, A.2    Tam, P.K.3
  • 16
    • 68549090621 scopus 로고    scopus 로고
    • Resistin is more abundant in liver than adipose tissue and is not upregulated by lipopolysaccharide
    • Szalowska E, Elferink MG, Hoek A, Groothuis GM, Vonk RJ. Resistin is more abundant in liver than adipose tissue and is not upregulated by lipopolysaccharide. J. Clin. Endocrinol. Metab. 2009; 94: 3051-3057.
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 3051-3057
    • Szalowska, E.1    Elferink, M.G.2    Hoek, A.3    Groothuis, G.M.4    Vonk, R.J.5
  • 17
    • 0036989990 scopus 로고    scopus 로고
    • Cloning, expression, and initial characterization of a novel cytokine-like gene family
    • Zhu Y, Xu G, Patel A etal. Cloning, expression, and initial characterization of a novel cytokine-like gene family. Genomics 2002; 80: 144-150.
    • (2002) Genomics , vol.80 , pp. 144-150
    • Zhu, Y.1    Xu, G.2    Patel, A.3
  • 18
    • 0042320939 scopus 로고    scopus 로고
    • Pancreatic-derived factor (FAM3B), a novel islet cytokine, induces apoptosis of insulin-secreting beta-cells
    • Cao X, Gao Z, Robert CE etal. Pancreatic-derived factor (FAM3B), a novel islet cytokine, induces apoptosis of insulin-secreting beta-cells. Diabetes 2003; 52: 2296-2303.
    • (2003) Diabetes , vol.52 , pp. 2296-2303
    • Cao, X.1    Gao, Z.2    Robert, C.E.3
  • 19
    • 33644688648 scopus 로고    scopus 로고
    • PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21)
    • Burkhardt BR, Greene SR, White P etal. PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21). Gene 2006; 369: 134-141.
    • (2006) Gene , vol.369 , pp. 134-141
    • Burkhardt, B.R.1    Greene, S.R.2    White, P.3
  • 20
    • 24944522425 scopus 로고    scopus 로고
    • Tissue-specific and glucose-responsive expression of the pancreatic derived factor (PANDER) promoter
    • Burkhardt BR, Yang MC, Robert CE etal. Tissue-specific and glucose-responsive expression of the pancreatic derived factor (PANDER) promoter. Biochim. Biophys. Acta 2005; 1730: 215-225.
    • (2005) Biochim. Biophys. Acta , vol.1730 , pp. 215-225
    • Burkhardt, B.R.1    Yang, M.C.2    Robert, C.E.3
  • 21
    • 25144489035 scopus 로고    scopus 로고
    • Effects of overexpression of pancreatic derived factor (FAM3B) in isolated mouse islets and insulin-secreting betaTC3 cells
    • Cao X, Yang J, Burkhardt BR etal. Effects of overexpression of pancreatic derived factor (FAM3B) in isolated mouse islets and insulin-secreting betaTC3 cells. Am. J. Physiol. Endocrinol. Metab. 2005; 289: E543-550.
    • (2005) Am. J. Physiol. Endocrinol. Metab. , vol.289
    • Cao, X.1    Yang, J.2    Burkhardt, B.R.3
  • 22
    • 79957521884 scopus 로고    scopus 로고
    • Pancreatic-derived factor promotes lipogenesis in the mouse liver: role of the Forkhead box 1 signaling pathway
    • Li J, Chi Y, Wang C etal. Pancreatic-derived factor promotes lipogenesis in the mouse liver: role of the Forkhead box 1 signaling pathway. Hepatology 2011; 53: 1906-1916.
    • (2011) Hepatology , vol.53 , pp. 1906-1916
    • Li, J.1    Chi, Y.2    Wang, C.3
  • 23
    • 77956387230 scopus 로고    scopus 로고
    • Targeted disruption of pancreatic-derived factor (PANDER, FAM3B) impairs pancreatic beta-cell function
    • Robert-Cooperman CE, Carnegie JR, Wilson CG etal. Targeted disruption of pancreatic-derived factor (PANDER, FAM3B) impairs pancreatic beta-cell function. Diabetes 2010; 59: 2209-2218.
    • (2010) Diabetes , vol.59 , pp. 2209-2218
    • Robert-Cooperman, C.E.1    Carnegie, J.R.2    Wilson, C.G.3
  • 24
    • 84863041791 scopus 로고    scopus 로고
    • Role of pancreatic-derived factor in type 2 diabetes: evidence from pancreatic beta cells and liver
    • Wang C, Burkhardt BR, Guan Y, Yang J. Role of pancreatic-derived factor in type 2 diabetes: evidence from pancreatic beta cells and liver. Nutr. Rev. 2012; 70: 100-106.
    • (2012) Nutr. Rev. , vol.70 , pp. 100-106
    • Wang, C.1    Burkhardt, B.R.2    Guan, Y.3    Yang, J.4
  • 25
    • 33644675373 scopus 로고    scopus 로고
    • Mechanisms of glucose-induced secretion of pancreatic-derived factor (PANDER or FAM3B) in pancreatic beta-cells
    • Yang J, Robert CE, Burkhardt BR etal. Mechanisms of glucose-induced secretion of pancreatic-derived factor (PANDER or FAM3B) in pancreatic beta-cells. Diabetes 2005; 54: 3217-3228.
    • (2005) Diabetes , vol.54 , pp. 3217-3228
    • Yang, J.1    Robert, C.E.2    Burkhardt, B.R.3
  • 26
    • 69949174739 scopus 로고    scopus 로고
    • PANDER binds to the liver cell membrane and inhibits insulin signaling in HepG2 cells
    • Yang J, Wang C, Li J etal. PANDER binds to the liver cell membrane and inhibits insulin signaling in HepG2 cells. FEBS Lett. 2009; 583: 3009-3015.
    • (2009) FEBS Lett. , vol.583 , pp. 3009-3015
    • Yang, J.1    Wang, C.2    Li, J.3
  • 27
    • 84867694937 scopus 로고    scopus 로고
    • Oit1/Fam3D, a gut-secreted protein displaying nutritional status-dependent regulation
    • de Wit NJ, Ijssennagger N, Oosterink E etal. Oit1/Fam3D, a gut-secreted protein displaying nutritional status-dependent regulation. J. Nutr. Biochem. 2012; 23: 1425-1433.
    • (2012) J. Nutr. Biochem. , vol.23 , pp. 1425-1433
    • de Wit, N.J.1    Ijssennagger, N.2    Oosterink, E.3
  • 28
    • 79955589918 scopus 로고    scopus 로고
    • PANDER KO mice on high-fat diet are glucose intolerant yet resistant to fasting hyperglycemia and hyperinsulinemia
    • Robert-Cooperman CE, Wilson CG, Burkhardt BR. PANDER KO mice on high-fat diet are glucose intolerant yet resistant to fasting hyperglycemia and hyperinsulinemia. FEBS Lett. 2011; 585: 1345-1349.
    • (2011) FEBS Lett. , vol.585 , pp. 1345-1349
    • Robert-Cooperman, C.E.1    Wilson, C.G.2    Burkhardt, B.R.3
  • 29
    • 79960370365 scopus 로고    scopus 로고
    • PANcreatic-DERived factor: novel hormone PANDERing to glucose regulation
    • Wilson CG, Robert-Cooperman CE, Burkhardt BR. PANcreatic-DERived factor: novel hormone PANDERing to glucose regulation. FEBS Lett. 2011; 585: 2137-2143.
    • (2011) FEBS Lett. , vol.585 , pp. 2137-2143
    • Wilson, C.G.1    Robert-Cooperman, C.E.2    Burkhardt, B.R.3
  • 30
    • 78049511254 scopus 로고    scopus 로고
    • Liver-specific overexpression of pancreatic-derived factor (PANDER) induces fasting hyperglycemia in mice
    • Wilson CG, Schupp M, Burkhardt BR, Wu J, Young RA, Wolf BA. Liver-specific overexpression of pancreatic-derived factor (PANDER) induces fasting hyperglycemia in mice. Endocrinology 2010; 151: 5174-5184.
    • (2010) Endocrinology , vol.151 , pp. 5174-5184
    • Wilson, C.G.1    Schupp, M.2    Burkhardt, B.R.3    Wu, J.4    Young, R.A.5    Wolf, B.A.6
  • 31
    • 81255157471 scopus 로고    scopus 로고
    • Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
    • Ellingsgaard H, Hauselmann I, Schuler B etal. Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat. Med. 2011; 17: 1481-1489.
    • (2011) Nat. Med. , vol.17 , pp. 1481-1489
    • Ellingsgaard, H.1    Hauselmann, I.2    Schuler, B.3
  • 33
    • 23644444932 scopus 로고    scopus 로고
    • Interferon-gamma-induced regulation of the pancreatic derived cytokine FAM3B in islets and insulin-secreting betaTC3 cells
    • Xu W, Gao Z, Wu J, Wolf BA. Interferon-gamma-induced regulation of the pancreatic derived cytokine FAM3B in islets and insulin-secreting betaTC3 cells. Mol. Cell. Endocrinol. 2005; 240: 74-81.
    • (2005) Mol. Cell. Endocrinol. , vol.240 , pp. 74-81
    • Xu, W.1    Gao, Z.2    Wu, J.3    Wolf, B.A.4
  • 34
    • 52049119306 scopus 로고    scopus 로고
    • PDX-1 interaction and regulation of the pancreatic derived factor (PANDER, FAM3B) promoter
    • Burkhardt BR, Cook JR, Young RA, Wolf BA. PDX-1 interaction and regulation of the pancreatic derived factor (PANDER, FAM3B) promoter. Biochim. Biophys. Acta 2008; 1779: 645-651.
    • (2008) Biochim. Biophys. Acta , vol.1779 , pp. 645-651
    • Burkhardt, B.R.1    Cook, J.R.2    Young, R.A.3    Wolf, B.A.4
  • 35
    • 38549159644 scopus 로고    scopus 로고
    • Mechanisms of glucose-induced expression of pancreatic-derived factor in pancreatic beta-cells
    • Wang O, Cai K, Pang S etal. Mechanisms of glucose-induced expression of pancreatic-derived factor in pancreatic beta-cells. Endocrinology 2008; 149: 672-680.
    • (2008) Endocrinology , vol.149 , pp. 672-680
    • Wang, O.1    Cai, K.2    Pang, S.3
  • 36
    • 80051558419 scopus 로고    scopus 로고
    • Upregulation of pancreatic derived factor (FAM3B) expression in pancreatic beta-cells by MCP-1 (CCL2)
    • Hou X, Wang O, Li Z etal. Upregulation of pancreatic derived factor (FAM3B) expression in pancreatic beta-cells by MCP-1 (CCL2). Mol. Cell. Endocrinol. 2011; 343: 18-24.
    • (2011) Mol. Cell. Endocrinol. , vol.343 , pp. 18-24
    • Hou, X.1    Wang, O.2    Li, Z.3
  • 37
    • 84861225959 scopus 로고    scopus 로고
    • Effect of PANDER in betaTC6-cell lipoapoptosis and the protective role of exendin-4
    • Xiang JN, Chen DL, Yang LY. Effect of PANDER in betaTC6-cell lipoapoptosis and the protective role of exendin-4. Biochem. Biophys. Res. Commun. 2012; 421: 701-706.
    • (2012) Biochem. Biophys. Res. Commun. , vol.421 , pp. 701-706
    • Xiang, J.N.1    Chen, D.L.2    Yang, L.Y.3
  • 38
    • 84895652183 scopus 로고    scopus 로고
    • Expression of PANDER in the pancreas of diabetic mice
    • Zhou Y, Wang C, Li J etal. Expression of PANDER in the pancreas of diabetic mice. Basic Clin. Med. 2012; 32: 756-760.
    • (2012) Basic Clin. Med. , vol.32 , pp. 756-760
    • Zhou, Y.1    Wang, C.2    Li, J.3
  • 39
    • 0033050114 scopus 로고    scopus 로고
    • Regulation of the insulin gene by glucose: stimulation of trans-activation potency of human PDX-1 N-terminal domain
    • Shushan EB, Cerasi E, Melloul D. Regulation of the insulin gene by glucose: stimulation of trans-activation potency of human PDX-1 N-terminal domain. DNA Cell Biol. 1999; 18: 471-479.
    • (1999) DNA Cell Biol. , vol.18 , pp. 471-479
    • Shushan, E.B.1    Cerasi, E.2    Melloul, D.3
  • 40
    • 77956359867 scopus 로고    scopus 로고
    • Transgenic mice overexpressing the novel islet specific cytokine, PANDER, exhibit glucose intolerance
    • Robert C, Wu J, Burkhardt BR, Wolf B. Transgenic mice overexpressing the novel islet specific cytokine, PANDER, exhibit glucose intolerance. Diabetes 2005; 54 (Suppl. 1): A400.
    • (2005) Diabetes , vol.54 , Issue.SUPPL. 1
    • Robert, C.1    Wu, J.2    Burkhardt, B.R.3    Wolf, B.4
  • 42
    • 23944511121 scopus 로고    scopus 로고
    • Structure-function studies of PANDER, an islet specific cytokine inducing cell death of insulin-secreting beta cells
    • Yang J, Gao Z, Robert CE etal. Structure-function studies of PANDER, an islet specific cytokine inducing cell death of insulin-secreting beta cells. Biochemistry 2005; 44: 11342-11352.
    • (2005) Biochemistry , vol.44 , pp. 11342-11352
    • Yang, J.1    Gao, Z.2    Robert, C.E.3
  • 43
    • 84863064760 scopus 로고    scopus 로고
    • Levels of serum pancreatic derived factor (PANDER) and their correlations with islet β cell function in newly diagnosed type 2 diabetic patients
    • Zhuang F, Guan Q, Gao L etal. Levels of serum pancreatic derived factor (PANDER) and their correlations with islet β cell function in newly diagnosed type 2 diabetic patients. J. Shandong Univ. (Health Sci.) 2010; 48: 1-4.
    • (2010) J. Shandong Univ. (Health Sci.) , vol.48 , pp. 1-4
    • Zhuang, F.1    Guan, Q.2    Gao, L.3
  • 44
    • 0025302287 scopus 로고
    • Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells
    • Kahn SE, D'Alessio DA, Schwartz MW etal. Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells. Diabetes 1990; 39: 634-638.
    • (1990) Diabetes , vol.39 , pp. 634-638
    • Kahn, S.E.1    D'Alessio, D.A.2    Schwartz, M.W.3
  • 45
    • 77955715434 scopus 로고    scopus 로고
    • Serum levels of proamylin and amylin in normal subjects and patients with impaired glucose regulation and type 2 diabetes mellitus
    • Zheng X, Ren W, Zhang S etal. Serum levels of proamylin and amylin in normal subjects and patients with impaired glucose regulation and type 2 diabetes mellitus. Acta Diabetol. 2010; 47: 265-270.
    • (2010) Acta Diabetol. , vol.47 , pp. 265-270
    • Zheng, X.1    Ren, W.2    Zhang, S.3
  • 46
    • 9444257636 scopus 로고    scopus 로고
    • Amylin agonists: a novel approach in the treatment of diabetes
    • Schmitz O, Brock B, Rungby J. Amylin agonists: a novel approach in the treatment of diabetes. Diabetes 2004; 53 (Suppl. 3): S233-238.
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 3
    • Schmitz, O.1    Brock, B.2    Rungby, J.3
  • 47
    • 84862902637 scopus 로고    scopus 로고
    • Control of energy homeostasis by amylin
    • Lutz TA. Control of energy homeostasis by amylin. Cell. Mol. Life Sci. 2012; 69: 1947-1965.
    • (2012) Cell. Mol. Life Sci. , vol.69 , pp. 1947-1965
    • Lutz, T.A.1
  • 48
    • 79956109928 scopus 로고    scopus 로고
    • Pramlintide and the treatment of diabetes: a review of the data since its introduction
    • Younk LM, Mikeladze M, Davis SN. Pramlintide and the treatment of diabetes: a review of the data since its introduction. Expert Opin. Pharmacother. 2010; 12: 1439-1451.
    • (2010) Expert Opin. Pharmacother. , vol.12 , pp. 1439-1451
    • Younk, L.M.1    Mikeladze, M.2    Davis, S.N.3
  • 49
    • 78651081169 scopus 로고    scopus 로고
    • Islet amyloid polypeptide acts on glucose-stimulated beta cells to reduce voltage-gated calcium channel activation, intracellular Ca(2+) concentration, and insulin secretion
    • Zhu T, Wang Y, He B, Zang J, He Q, Zhang W. Islet amyloid polypeptide acts on glucose-stimulated beta cells to reduce voltage-gated calcium channel activation, intracellular Ca(2+) concentration, and insulin secretion. Diabetes Metab. Res. Rev. 2011; 27: 28-34.
    • (2011) Diabetes Metab. Res. Rev. , vol.27 , pp. 28-34
    • Zhu, T.1    Wang, Y.2    He, B.3    Zang, J.4    He, Q.5    Zhang, W.6
  • 50
    • 79952101635 scopus 로고    scopus 로고
    • Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: an effect attenuated by phycocyanin
    • Li XL, Chen T, Wong YS etal. Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: an effect attenuated by phycocyanin. Int. J. Biochem. Cell Biol. 2011; 43: 525-534.
    • (2011) Int. J. Biochem. Cell Biol. , vol.43 , pp. 525-534
    • Li, X.L.1    Chen, T.2    Wong, Y.S.3
  • 51
    • 0029901739 scopus 로고    scopus 로고
    • Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide
    • Janson J, Soeller WC, Roche PC etal. Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide. Proc. Natl Acad. Sci. U. S. A. 1996; 93: 7283-7288.
    • (1996) Proc. Natl Acad. Sci. U. S. A. , vol.93 , pp. 7283-7288
    • Janson, J.1    Soeller, W.C.2    Roche, P.C.3
  • 52
    • 2542581025 scopus 로고    scopus 로고
    • Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes
    • Butler AE, Jang J, Gurlo T, Carty MD, Soeller WC, Butler PC. Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes. Diabetes 2004; 53: 1509-1516.
    • (2004) Diabetes , vol.53 , pp. 1509-1516
    • Butler, A.E.1    Jang, J.2    Gurlo, T.3    Carty, M.D.4    Soeller, W.C.5    Butler, P.C.6
  • 53
    • 0032544715 scopus 로고    scopus 로고
    • Increased insulin secretion and glucose tolerance in mice lacking islet amyloid polypeptide (amylin)
    • Gebre-Medhin S, Mulder H, Pekny M etal. Increased insulin secretion and glucose tolerance in mice lacking islet amyloid polypeptide (amylin). Biochem. Biophys. Res. Commun. 1998; 250: 271-277.
    • (1998) Biochem. Biophys. Res. Commun. , vol.250 , pp. 271-277
    • Gebre-Medhin, S.1    Mulder, H.2    Pekny, M.3
  • 54
    • 0034999864 scopus 로고    scopus 로고
    • Evidence that amylin stimulates lipolysis in vivo: a possible mediator of induced insulin resistance
    • Ye JM, Lim-Fraser M, Cooney GJ etal. Evidence that amylin stimulates lipolysis in vivo: a possible mediator of induced insulin resistance. Am. J. Physiol. Endocrinol. Metab. 2001; 280: E562-569.
    • (2001) Am. J. Physiol. Endocrinol. Metab. , vol.280
    • Ye, J.M.1    Lim-Fraser, M.2    Cooney, G.J.3
  • 55
    • 0029009485 scopus 로고
    • Amylin-mediated reduction in insulin sensitivity corresponds to reduced insulin receptor kinase activity in the rat in vivo
    • Bryer-Ash M, Follett L, Hodges N, Wimalawansa S. Amylin-mediated reduction in insulin sensitivity corresponds to reduced insulin receptor kinase activity in the rat in vivo. Metabolism 1995; 44: 705-711.
    • (1995) Metabolism , vol.44 , pp. 705-711
    • Bryer-Ash, M.1    Follett, L.2    Hodges, N.3    Wimalawansa, S.4
  • 56
    • 47949110973 scopus 로고    scopus 로고
    • White matter lesions in the brain with frontotemporal lobar degeneration with motor neuron disease: TDP-43-immunopositive inclusions co-localize with p62, but not ubiquitin
    • Hiji M, Takahashi T, Fukuba H, Yamashita H, Kohriyama T, Matsumoto M. White matter lesions in the brain with frontotemporal lobar degeneration with motor neuron disease: TDP-43-immunopositive inclusions co-localize with p62, but not ubiquitin. Acta Neuropathol. 2008; 116: 183-191.
    • (2008) Acta Neuropathol. , vol.116 , pp. 183-191
    • Hiji, M.1    Takahashi, T.2    Fukuba, H.3    Yamashita, H.4    Kohriyama, T.5    Matsumoto, M.6
  • 57
    • 67049143907 scopus 로고    scopus 로고
    • FoxO1 and hepatic lipid metabolism
    • Sparks JD, Dong HH. FoxO1 and hepatic lipid metabolism. Curr. Opin. Lipidol. 2009; 20: 217-226.
    • (2009) Curr. Opin. Lipidol. , vol.20 , pp. 217-226
    • Sparks, J.D.1    Dong, H.H.2
  • 58
    • 45749133797 scopus 로고    scopus 로고
    • FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice
    • Kamagate A, Qu S, Perdomo G etal. FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice. J. Clin. Invest. 2008; 118: 2347-2364.
    • (2008) J. Clin. Invest. , vol.118 , pp. 2347-2364
    • Kamagate, A.1    Qu, S.2    Perdomo, G.3
  • 59
    • 45749114635 scopus 로고    scopus 로고
    • Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis
    • Valenti L, Rametta R, Dongiovanni P etal. Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis. Diabetes 2008; 57: 1355-1362.
    • (2008) Diabetes , vol.57 , pp. 1355-1362
    • Valenti, L.1    Rametta, R.2    Dongiovanni, P.3
  • 60
    • 80052098833 scopus 로고    scopus 로고
    • Suppression of FoxO1 activity by long-chain fatty acyl analogs
    • Zatara G, Hertz R, Shaked M etal. Suppression of FoxO1 activity by long-chain fatty acyl analogs. Diabetes 2011; 60: 1872-1881.
    • (2011) Diabetes , vol.60 , pp. 1872-1881
    • Zatara, G.1    Hertz, R.2    Shaked, M.3
  • 61
    • 67650914230 scopus 로고    scopus 로고
    • AMPK in health and disease
    • Steinberg GR, Kemp BE. AMPK in health and disease. Physiol. Rev. 2009; 89: 1025-1078.
    • (2009) Physiol. Rev. , vol.89 , pp. 1025-1078
    • Steinberg, G.R.1    Kemp, B.E.2
  • 62
    • 80051706346 scopus 로고    scopus 로고
    • Role for PPARgamma in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts
    • Moran-Salvador E, Lopez-Parra M, Garcia-Alonso V etal. Role for PPARgamma in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts. FASEB J. 2011; 25: 2538-2550.
    • (2011) FASEB J. , vol.25 , pp. 2538-2550
    • Moran-Salvador, E.1    Lopez-Parra, M.2    Garcia-Alonso, V.3
  • 63
    • 0141446024 scopus 로고    scopus 로고
    • Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass
    • Gavrilova O, Haluzik M, Matsusue K etal. Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. J. Biol. Chem. 2003; 278: 34268-34276.
    • (2003) J. Biol. Chem. , vol.278 , pp. 34268-34276
    • Gavrilova, O.1    Haluzik, M.2    Matsusue, K.3
  • 64
    • 0037373008 scopus 로고    scopus 로고
    • Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes
    • Matsusue K, Haluzik M, Lambert G etal. Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes. J. Clin. Invest. 2003; 111: 737-747.
    • (2003) J. Clin. Invest. , vol.111 , pp. 737-747
    • Matsusue, K.1    Haluzik, M.2    Lambert, G.3
  • 65
    • 38649096259 scopus 로고    scopus 로고
    • Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis
    • Zhou J, Febbraio M, Wada T etal. Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis. Gastroenterology 2008; 134: 556-567.
    • (2008) Gastroenterology , vol.134 , pp. 556-567
    • Zhou, J.1    Febbraio, M.2    Wada, T.3
  • 66
    • 80053450975 scopus 로고    scopus 로고
    • The emerging roles of fatty acid translocase/CD36 and the aryl hydrocarbon receptor in fatty liver disease
    • He J, Lee JH, Febbraio M, Xie W. The emerging roles of fatty acid translocase/CD36 and the aryl hydrocarbon receptor in fatty liver disease. Exp. Biol. Med. (Maywood) 2011; 236: 1116-1121.
    • (2011) Exp. Biol. Med. (Maywood) , vol.236 , pp. 1116-1121
    • He, J.1    Lee, J.H.2    Febbraio, M.3    Xie, W.4
  • 67
    • 36849037401 scopus 로고    scopus 로고
    • Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity
    • Koonen DP, Jacobs RL, Febbraio M etal. Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity. Diabetes 2007; 56: 2863-2871.
    • (2007) Diabetes , vol.56 , pp. 2863-2871
    • Koonen, D.P.1    Jacobs, R.L.2    Febbraio, M.3
  • 68
    • 0032887065 scopus 로고    scopus 로고
    • Human liver-specific very-long-chain acyl-coenzyme A synthetase: cDNA cloning and characterization of a second enzymatically active protein
    • Steinberg SJ, Wang SJ, McGuinness MC, Watkins PA. Human liver-specific very-long-chain acyl-coenzyme A synthetase: cDNA cloning and characterization of a second enzymatically active protein. Mol. Genet. Metab. 1999; 68: 32-42.
    • (1999) Mol. Genet. Metab. , vol.68 , pp. 32-42
    • Steinberg, S.J.1    Wang, S.J.2    McGuinness, M.C.3    Watkins, P.A.4
  • 69
    • 80054745073 scopus 로고    scopus 로고
    • Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells
    • Krammer J, Digel M, Ehehalt F, Stremmel W, Fullekrug J, Ehehalt R. Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells. Int. J. Med. Sci. 2011; 8: 599-614.
    • (2011) Int. J. Med. Sci. , vol.8 , pp. 599-614
    • Krammer, J.1    Digel, M.2    Ehehalt, F.3    Stremmel, W.4    Fullekrug, J.5    Ehehalt, R.6
  • 70
    • 16644375635 scopus 로고    scopus 로고
    • Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR
    • Solmi R, De Sanctis P, Zucchini C etal. Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR. Int. J. Oncol. 2004; 25: 1049-1056.
    • (2004) Int. J. Oncol. , vol.25 , pp. 1049-1056
    • Solmi, R.1    De Sanctis, P.2    Zucchini, C.3
  • 71
    • 33748168727 scopus 로고    scopus 로고
    • ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells
    • Waerner T, Alacakaptan M, Tamir I etal. ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells. Cancer Cell 2006; 10: 227-239.
    • (2006) Cancer Cell , vol.10 , pp. 227-239
    • Waerner, T.1    Alacakaptan, M.2    Tamir, I.3
  • 72
    • 31644434206 scopus 로고    scopus 로고
    • Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach
    • Gronborg M, Kristiansen TZ, Iwahori A etal. Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach. Mol. Cell. Proteomics 2006; 5: 157-171.
    • (2006) Mol. Cell. Proteomics , vol.5 , pp. 157-171
    • Gronborg, M.1    Kristiansen, T.Z.2    Iwahori, A.3
  • 73
    • 2942513139 scopus 로고    scopus 로고
    • Genomic organization and expression analysis of the murine Fam3c gene
    • Pilipenko VV, Reece A, Choo DI, Greinwald JH Jr. Genomic organization and expression analysis of the murine Fam3c gene. Gene 2004; 335: 159-168.
    • (2004) Gene , vol.335 , pp. 159-168
    • Pilipenko, V.V.1    Reece, A.2    Choo, D.I.3    Greinwald Jr, J.H.4


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